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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

NeuroD1 localizes to the presumptive ganglia and gut of the sea urchin larvae

Authors:
Konrad KD, Song JL
Citation:
microPubl Biol. 2022;[Epub] doi:10.17912/micropub.biology.000682
Epub:
Not Epub
Abstract:
NeuroD is a transcription factor (TF) that plays a dual role in vertebrate neurogenesis and glucose homeostasis in the pancreas...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Konrad KD, Song JL. NeuroD1 localizes to the presumptive ganglia and gut of the sea urchin larvae. microPubl Biol. 2022;[Epub] doi:10.17912/micropub.biology.000682.

Requirement of Zebrafish Adcy3a and Adcy5 in Melanosome Dispersion and Melanocyte Stripe Formation

Authors:
Zhang L, Wan M, Tohti R, Jin D, Zhong TP
Citation:
Int J Mol Sci. 2022;23:14182. doi:/10.3390/ijms232214182
Epub:
Not Epub
Abstract:
cAMP-PKA signaling plays a pivotal role in melanin synthesis and melanosome transport by responding to the binding of the α-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang L, Wan M, Tohti R, Jin D, Zhong TP. Requirement of Zebrafish Adcy3a and Adcy5 in Melanosome Dispersion and Melanocyte Stripe Formation. Int J Mol Sci. 2022;23:14182. doi:/10.3390/ijms232214182.

Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration

Authors:
Porpiglia E, Mai T, Kraft P, Holbrook CA, de Morree A, Gonzalez VD, Hilgendorf KI, Frésard L, Trejo A, Bhimaraju S, Jackson PK, Fantl WJ, Blau HM
Citation:
Cell Stem Cell. 2022;[Epub] doi:10.1016/j.stem.2022.10.009
Epub:
Yes
Abstract:
In aging, skeletal muscle strength and regenerative capacity decline, due in part to functional impairment of muscle stem cells...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse muscle stem cells
Citation Extract:
Porpiglia E, Mai T, Kraft P, Holbrook CA, de Morree A, Gonzalez VD, Hilgendorf KI, Frésard L, Trejo A, Bhimaraju S, Jackson PK, Fantl WJ, Blau HM. Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration. Cell Stem Cell. 2022;[Epub] doi:10.1016/j.stem.2022.10.009.

X-linked variations in SHROOM4 are implicated in congenital anomalies of the urinary tract and the anorectal, cardiovascular and central nervous systems

Authors:
Kolvenbach CM, Felger T, Schierbaum L, Thiffault I, Pastinen T, Szczepańska M, Zaniew M, Adamczyk P, Bayat A, Yilmaz Ö, Lindenberg TT, Thiele H, Hildebrandt F, Hinderhofer K, Moog U, Hilger AC, Sullivan B, Bartik L, Gnyś P, Grote P, Odermatt B, Reutter HM, Dworschak GC
Citation:
J Med Genet. 2022 Nov 15:jmedgenet-2022-108738. doi: 10.1136/jmg-2022-108738. Online ahead of print
Epub:
Yes
Abstract:
Background: SHROOM4 is thought to play an important role in cytoskeletal modification and development of the early nervous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kolvenbach CM, Felger T, Schierbaum L, Thiffault I, Pastinen T, Szczepańska M, Zaniew M, Adamczyk P, Bayat A, Yilmaz Ö, Lindenberg TT, Thiele H, Hildebrandt F, Hinderhofer K, Moog U, Hilger AC, Sullivan B, Bartik L, Gnyś P, Grote P, Odermatt B, Reutter HM, Dworschak GC. X-linked variations in SHROOM4 are implicated in congenital anomalies of the urinary tract and the anorectal, cardiovascular and central nervous systems. J Med Genet. 2022 Nov 15:jmedgenet-2022-108738. doi: 10.1136/jmg-2022-108738. Online ahead of print.

Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction

Authors:
Pegge J, Tatsinkam AJ, Rider CC, Bell E
Citation:
Dev Biol. 2020 Apr 15;460(2):108-114. doi: 10.1016/j.ydbio.2019.12.015. Epub 2019 Dec 25
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP) signalling is key to many developmental processes, including early regionalisation of the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pegge J, Tatsinkam AJ, Rider CC, Bell E. Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction. Dev Biol. 2020 Apr 15;460(2):108-114. doi: 10.1016/j.ydbio.2019.12.015. Epub 2019 Dec 25.

Zebrafish: A Tractable Model for Analysis of T Cell Development

Authors:
Sertori R, Zhang Y, Wiest DL
Citation:
In: Bosselut, R., Vacchio, M.S. (eds) T-Cell Development. Methods Mol Biol. 2023;vol 2580. Humana, New York, NY. doi:10.1007/978-1-0716-2740-2_22
Epub:
Not Epub
Abstract:
While the zebrafish has for some time been regarded as a powerful model organism with which to study early events in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sertori R, Zhang Y, Wiest DL. Zebrafish: A Tractable Model for Analysis of T Cell Development. In: Bosselut, R., Vacchio, M.S. (eds) T-Cell Development. Methods Mol Biol. 2023;vol 2580. Humana, New York, NY. doi:10.1007/978-1-0716-2740-2_22.

Noncanonical protease-activated receptor 1 regulates lymphatic differentiation in zebrafish

Authors:
Lei D, Zhang X, Rouf MA, Mahendra Y, Wen L, Li Y, Zhang X, Li L, Wang L, Zhang T, Wang G, Wang Y
Citation:
iScience. 2021 Oct 30;24(11):103386. doi: 10.1016/j.isci.2021.103386. eCollection 2021 Nov 19
Epub:
Not Epub
Abstract:
The differentiation of lymphatic progenitors is a crucial step in lymphangiogenesis. However, its underlying mechanism remains...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lei D, Zhang X, Rouf MA, Mahendra Y, Wen L, Li Y, Zhang X, Li L, Wang L, Zhang T, Wang G, Wang Y. Noncanonical protease-activated receptor 1 regulates lymphatic differentiation in zebrafish. iScience. 2021 Oct 30;24(11):103386. doi: 10.1016/j.isci.2021.103386. eCollection 2021 Nov 19.

Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish

Authors:
Fasano G, Muto V, Radio FC, Venditti M, Mosaddeghzadeh N, Coppola S, Paradisi G, Zara E, Bazgir F, Ziegler A, Chillemi G, Bertuccini L, Tinari A, Vetro A, Pantaleoni F, Pizzi S, Conti LA, Petrini S, Bruselles A, Prandi IG, Mancini C, Chandramouli B, Barth M, Bris C, Milani D, Selicorni A, Macchiaiolo M, Gonfiantini MV, Bartuli A, Mariani R, Curry CJ, Guerrini R, Slavotinek A, Iascone M, Dallapiccola B, Ahmadian MR, Lauri A, Tartaglia M
Citation:
Nat Commun. 2022 Nov 11;13(1):6841. doi: 10.1038/s41467-022-34354-x
Epub:
Not Epub
Abstract:
Vesicle biogenesis, trafficking and signaling via Endoplasmic reticulum-Golgi network support essential developmental processes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fasano G, Muto V, Radio FC, Venditti M, Mosaddeghzadeh N, Coppola S, Paradisi G, Zara E, Bazgir F, Ziegler A, Chillemi G, Bertuccini L, Tinari A, Vetro A, Pantaleoni F, Pizzi S, Conti LA, Petrini S, Bruselles A, Prandi IG, Mancini C, Chandramouli B, Barth M, Bris C, Milani D, Selicorni A, Macchiaiolo M, Gonfiantini MV, Bartuli A, Mariani R, Curry CJ, Guerrini R, Slavotinek A, Iascone M, Dallapiccola B, Ahmadian MR, Lauri A, Tartaglia M. Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish. Nat Commun. 2022 Nov 11;13(1):6841. doi: 10.1038/s41467-022-34354-x.

The circadian rhythm regulates branched-chain amino acids metabolism in fast muscle of Chinese perch (Siniperca chuatsi) during short-term fasting by Clock-KLF15-Bcat2 pathway

Authors:
Zhu X, Liu J, Cai M, Bao L, Pan Y, Wu P, Chu W, Zhang J
Citation:
Br J Nutr. 2022 Nov 14:1-31. doi: 10.1017/S0007114522003646. Online ahead of print
Epub:
Not Epub
Abstract:
As an internal time keeping mechanism, circadian rhythm plays crucial role in maintaining homeostasis when in response to...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Siniperca chuatsi (Chinese perch)
Citation Extract:
Zhu X, Liu J, Cai M, Bao L, Pan Y, Wu P, Chu W, Zhang J. The circadian rhythm regulates branched-chain amino acids metabolism in fast muscle of Chinese perch (Siniperca chuatsi) during short-term fasting by Clock-KLF15-Bcat2 pathway. Br J Nutr. 2022 Nov 14:1-31. doi: 10.1017/S0007114522003646. Online ahead of print.

A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience

Authors:
Wang C, Wang B, Pandey T, Long Y, Zhang J, Oh F, Sima J, Guo R, Liu Y, Zhang C, Mukherjee S, Bassik M, Lin W, Deng H, Vale G, McDonald J, Shen K, Ma DK
Citation:
Nat Comm. 2022;13:6805. doi:10.1038/s41467-022-34450-y
Epub:
Not Epub
Abstract:
Cells adapt to cold by increasing levels of unsaturated phospholipids and membrane fluidity through conserved homeostatic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang C, Wang B, Pandey T, Long Y, Zhang J, Oh F, Sima J, Guo R, Liu Y, Zhang C, Mukherjee S, Bassik M, Lin W, Deng H, Vale G, McDonald J, Shen K, Ma DK. A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience. Nat Comm. 2022;13:6805. doi:10.1038/s41467-022-34450-y.

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