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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

eif4ebp3l-A New Affector of Zebrafish Angiogenesis and Heart Regeneration?

Authors:
Born LI, Andree T, Frank S, Hübner J, Link S, Langheine M, Charlet A, Esser JS, Brehm R, Moser M
Citation:
Int J Mol Sci. 2022 Sep 3;23(17):10075. doi: 10.3390/ijms231710075
Epub:
Not Epub
Abstract:
The eukaryotic initiation factor 4E binding protein (4E-BP) family is involved in translational control of cell proliferation...
Link:
https://www.mdpi.com/1422-0067/23/17/10075
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Born LI, Andree T, Frank S, Hübner J, Link S, Langheine M, Charlet A, Esser JS, Brehm R, Moser M. eif4ebp3l-A New Affector of Zebrafish Angiogenesis and Heart Regeneration?. Int J Mol Sci. 2022 Sep 3;23(17):10075. doi: 10.3390/ijms231710075.

Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia

Authors:
Guernsey DL, Jiang H, Campagna DR, Evans SC, Ferguson M, Kellogg MD, Lachance M, Matsuoka M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman M, Dyack S, Fernandez CV, Samuels ME
Citation:
Nat Genet. 2009 Jun;41(6):651-3. doi: 10.1038/ng.359. Epub 2009 May 3
Epub:
Not Epub
Abstract:
The sideroblastic anemias are a heterogeneous group of congenital and acquired hematological disorders whose morphological...
Link:
https://www.nature.com/articles/ng.359
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guernsey DL, Jiang H, Campagna DR, Evans SC, Ferguson M, Kellogg MD, Lachance M, Matsuoka M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman M, Dyack S, Fernandez CV, Samuels ME. Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia. Nat Genet. 2009 Jun;41(6):651-3. doi: 10.1038/ng.359. Epub 2009 May 3.

Neuromuscular NMDA receptors regulate developmental synaptic depletion

Authors:
Joy E
Citation:
Mult Scler. 2022;9(5):442 doi:10.35248/2376-0389.22.9.5.442
Epub:
Not Epub
Abstract:
[no abstract]
Link:
https://www.iomcworld.org/open-access/neuromuscular-nmda-receptors-regulate-developmental-synaptic-depletion.pdf
Delivery Method:
Vivo-Morpholino
Citation Extract:
Joy E. Neuromuscular NMDA receptors regulate developmental synaptic depletion. Mult Scler. 2022;9(5):442 doi:10.35248/2376-0389.22.9.5.442.

MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis

Authors:
Gan J, Liu S, Zhang Y, He L, Bai L, Liao R, Zhao J, Guo M, Jiang W, Li J, Li Q, Mu G, Wu Y, Wang X, Zhang X, Zhou D, Lv H, Wang Z, Zhang Y, Qian C, Feng M, Chen H, Meng Q, Huang X
Citation:
Exp Mol Med. 2022 Aug;54(8):1290-1305. doi: 10.1038/s12276-022-00837-6. Epub 2022 Aug 30
Epub:
Not Epub
Abstract:
The functional role of microRNA-375 (miR-375) in the development of prostate cancer (PCa) remains controversial. Previously, we...
Link:
https://www.nature.com/articles/s12276-022-00837-6
Delivery Method:
exosomes
Organism or Cell Type:
mice BALB/c
Citation Extract:
Gan J, Liu S, Zhang Y, He L, Bai L, Liao R, Zhao J, Guo M, Jiang W, Li J, Li Q, Mu G, Wu Y, Wang X, Zhang X, Zhou D, Lv H, Wang Z, Zhang Y, Qian C, Feng M, Chen H, Meng Q, Huang X. MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis. Exp Mol Med. 2022 Aug;54(8):1290-1305. doi: 10.1038/s12276-022-00837-6. Epub 2022 Aug 30.

A lysosomal regulatory circuit essential for the development and function of microglia

Authors:
Iyer H, Shen K, Meireles AM, Talbot WS
Citation:
Sci Adv. 2022 Sep 2;8(35):eabp8321. doi: 10.1126/sciadv.abp8321. Epub 2022 Aug 31
Epub:
Not Epub
Abstract:
As the primary phagocytic cells of the central nervous system, microglia exquisitely regulate their lysosomal activity to...
Link:
https://www.science.org/doi/10.1126/sciadv.abp8321
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iyer H, Shen K, Meireles AM, Talbot WS. A lysosomal regulatory circuit essential for the development and function of microglia. Sci Adv. 2022 Sep 2;8(35):eabp8321. doi: 10.1126/sciadv.abp8321. Epub 2022 Aug 31.

Optical Control of MicroRNA Function in Zebrafish Embryos

Authors:
Brown W, Bardhan A, Darrah K, Tsang M, Deiters A
Citation:
J Am Chem Soc. 2022 Sep 8. doi: 10.1021/jacs.2c04479. Online ahead of print
Epub:
Yes
Abstract:
MicroRNAs play crucial and dynamic roles in vertebrate development and diseases. Some, like miR-430, are highly expressed...
Link:
https://pubs.acs.org/doi/10.1021/jacs.2c04479
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brown W, Bardhan A, Darrah K, Tsang M, Deiters A. Optical Control of MicroRNA Function in Zebrafish Embryos. J Am Chem Soc. 2022 Sep 8. doi: 10.1021/jacs.2c04479. Online ahead of print.

Hemifacial microsomia is linked a rare homozygous variant V162I in FRK and validated in zebrafish

Authors:
Xiong J, Wang X, Fan C, Yan J, Zhu J, Cai T
Citation:
Oral Dis. 2022 Sep 7. doi: 10.1111/odi.14372. Online ahead of print
Epub:
Yes
Abstract:
Objectives: Hemifacial microsomia (HFM) is a common birth defect involving the first and second branchial arch derivatives....
Link:
https://onlinelibrary.wiley.com/doi/10.1111/odi.14372
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiong J, Wang X, Fan C, Yan J, Zhu J, Cai T . Hemifacial microsomia is linked a rare homozygous variant V162I in FRK and validated in zebrafish. Oral Dis. 2022 Sep 7. doi: 10.1111/odi.14372. Online ahead of print.

Bicyclic Caged Morpholino Oligonucleotides for Optical Gene Silencing

Authors:
Pattanayak S, Sarode BR, Deiters A, Chen JK
Citation:
Chembiochem. 2022 Sep 6. doi: 10.1002/cbic.202200374. Online ahead of print
Epub:
Not Epub
Abstract:
Caged morpholino oligonucleotides (cMOs) are synthetic tools that allow light-inducible gene silencing in live organisms....
Link:
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202200374
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pattanayak S, Sarode BR, Deiters A, Chen JK. Bicyclic Caged Morpholino Oligonucleotides for Optical Gene Silencing. Chembiochem. 2022 Sep 6. doi: 10.1002/cbic.202200374. Online ahead of print.

[Construction of zebrafish models for screening intracranial hemorrhage associated genes]

Authors:
Yan SY, Zhang XR, Zhang RJ, Ma L, Li H, He M, Wu C, Xiao AQ, You C, Liu Y, Wang YQ, Tian R
Citation:
Zhonghua Yi Xue Za Zhi. 2022 Sep 6;102(33):2619-2623. doi:10.3760/cma.j.cn112137-20211206-02713
Epub:
Not Epub
Abstract:
Objective: To construct zebrafish models for the screening of intracranial hemorrhage (ICH) associated genes. Methods: ICH...
Link:
http://rs.yiigle.com/CN112137202233/1423148.htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yan SY, Zhang XR, Zhang RJ, Ma L, Li H, He M, Wu C, Xiao AQ, You C, Liu Y, Wang YQ, Tian R. [Construction of zebrafish models for screening intracranial hemorrhage associated genes]. Zhonghua Yi Xue Za Zhi. 2022 Sep 6;102(33):2619-2623. doi:10.3760/cma.j.cn112137-20211206-02713.

Cystathionine β-synthase is required for oocyte quality by ensuring proper meiotic spindle assembly

Authors:
Cao Y, Zhu X, Zhen P, Tian Y, Ji D, Xue K, Yan W, Chai J, Liu H, Wang W
Citation:
Cell Prolif. 2022 Aug 19:e13322. doi: 10.1111/cpr.13322. Online ahead of print
Epub:
Yes
Abstract:
Objectives: Poor oocyte quality is detrimental to fertilization and embryo development, which causes infertility. Cystathionine...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/cpr.13322
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Cao Y, Zhu X, Zhen P, Tian Y, Ji D, Xue K, Yan W, Chai J, Liu H, Wang W. Cystathionine β-synthase is required for oocyte quality by ensuring proper meiotic spindle assembly. Cell Prolif. 2022 Aug 19:e13322. doi: 10.1111/cpr.13322. Online ahead of print.

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