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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Ash2l, an obligatory component of H3K4 methylation complexes, regulates neural crest development
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Citation:
Dev Biol. 2022 Sep 23:S0012-1606(22)00179-8. doi: 10.1016/j.ydbio.2022.09.008. Online ahead of print Epub:
Yes Abstract:
The vertebrate nervous system develops from embryonic neural plate and neural crest. Although genetic mechanisms governing... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mohammadparast S, Chang C. Ash2l, an obligatory component of H3K4 methylation complexes, regulates neural crest development. Dev Biol. 2022 Sep 23:S0012-1606(22)00179-8. doi: 10.1016/j.ydbio.2022.09.008. Online ahead of print. |
Exon skipping induces uniform dystrophin rescue with dose-dependent restoration of serum miRNA biomarkers and muscle biophysical properties
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Citation:
Mol Ther Nucleic Acids. 2022 Aug 25;29:955-968. doi: 10.1016/j.omtn.2022.08.033. eCollection 2022 Epub:
Not Epub Abstract:
Therapies that restore dystrophin expression are presumed to correct Duchenne muscular dystrophy (DMD), with antisense-mediated... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Chwalenia K, Oieni J, Zemła J, Lekka M, Ahlskog N, Coenen-Stass AML, McClorey G, Wood MJA, Lomonosova Y, Roberts TC. Exon skipping induces uniform dystrophin rescue with dose-dependent restoration of serum miRNA biomarkers and muscle biophysical properties. Mol Ther Nucleic Acids. 2022 Aug 25;29:955-968. doi: 10.1016/j.omtn.2022.08.033. eCollection 2022. |
Regulation of Nodal signaling propagation by receptor interactions and positive feedback
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Citation:
Elife. 2022 Sep 23;11:e66397. doi: 10.7554/eLife.66397. Online ahead of print Epub:
Not Epub Abstract:
During vertebrate embryogenesis, the germ layers are patterned by secreted Nodal signals. In the classical model, Nodals elicit... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Preiß H, Kögler AC, Mörsdorf D, Čapek D, Soh GH, Rogers KW, Morales-Navarrete H, Almuedo-Castillo M, Müller P. Regulation of Nodal signaling propagation by receptor interactions and positive feedback. Elife. 2022 Sep 23;11:e66397. doi: 10.7554/eLife.66397. Online ahead of print. |
Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality
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Citation:
Science. 2022 Sep 23;377(6613):1413-1419. doi: 10.1126/science.abo4837. Epub 2022 Sep 22 Epub:
Not Epub Abstract:
Tissue-specific stem cells persist for a lifetime and can differentiate to maintain homeostasis or transform to initiate cancer... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wattrus SJ, Smith ML, Rodrigues CP, Hagedorn EJ, Kim JW, Budnik B, Zon LI. Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality. Science. 2022 Sep 23;377(6613):1413-1419. doi: 10.1126/science.abo4837. Epub 2022 Sep 22. |
Adamts10 controls transforming growth factor β family signaling that contributes to retinal ganglion cell development
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Citation:
Front Mol Biosci. 2022 Sep 6;9:989851. doi: 10.3389/fmolb.2022.989851. eCollection 2022 Epub:
Not Epub Abstract:
Although mutations in ADAMTS10 have long been known to cause autosomal recessive Weill-Marchesani Syndrome which is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wareham LK, Whitener AE, Wu HJ, Wu SY, Mchaourab HS, Mortlock DP, Kuchtey RW, Kuchtey J. Adamts10 controls transforming growth factor β family signaling that contributes to retinal ganglion cell development. Front Mol Biosci. 2022 Sep 6;9:989851. doi: 10.3389/fmolb.2022.989851. eCollection 2022. |
AMBRA1 p.Gln30Arg Mutation, Identified in a Cowden Syndrome Family, Exhibits Hyperproliferative Potential in hTERT-RPE1 Cells
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Citation:
Int J Mol Sci. 2022;23(19):11124. doi:10.3390/ijms231911124 Epub:
Not Epub Abstract:
Cowden syndrome (CS) is a rare autosomal dominant disorder associated with multiple hamartomatous and neoplastic lesions in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Revathidevi S, Hosomichi K, Natsume T, Nakaoka H, Fujito NT, Akatsuka H, Sato T, Munirajan AK, Inoue I. AMBRA1 p.Gln30Arg Mutation, Identified in a Cowden Syndrome Family, Exhibits Hyperproliferative Potential in hTERT-RPE1 Cells. Int J Mol Sci. 2022;23(19):11124. doi:10.3390/ijms231911124. |
The Shape of the Jaw - Zebrafish Col11a1a Regulates Meckel’s Cartilage Morphogenesis and Mineralization
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Citation:
J Dev Biol. 2022;10(4):40. doi:10.3390/jdb10040040 Epub:
Not Epub Abstract:
The expression of the col11a1a gene is essential for normal skeletal development, affecting both cartilage and bone. Loss of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reeck JC, Oxford JT. The Shape of the Jaw - Zebrafish Col11a1a Regulates Meckel’s Cartilage Morphogenesis and Mineralization. J Dev Biol. 2022;10(4):40. doi:10.3390/jdb10040040. |
A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish
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Citation:
Hum Molec Genet. 2022;ddac229. doi:10.1093/hmg/ddac229 Epub:
Not Epub Abstract:
Hereditary hearing loss is a highly genetically heterogeneous disorder. More than 150 genes have been identified to link to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li Y, Ning G, Kang B, Zhu J, Wang X-Y, Wang Q, Cai T. A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish. Hum Molec Genet. 2022;ddac229. doi:10.1093/hmg/ddac229. |
Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish
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Citation:
Commun Biol. 2022;5:996. doi:10.1038/s42003-022-03826-7 Epub:
Not Epub Abstract:
Clockwise rotation of the primitive heart tube, a process regulated by restricted left-sided Nodal signaling, is the first... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kidokoro H, Saijoh Y, Schoenwolf GC. Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish. Commun Biol. 2022;5:996. doi:10.1038/s42003-022-03826-7. |
Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish
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Citation:
Nat Commun. 2022;13:5520. doi:10.1038/s41467-022-33260-6 Epub:
Not Epub Abstract:
Adenosine deaminases (ADARs) catalyze the deamination of adenosine to inosine, also known as A-to-I editing, in RNA. Although A... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Niescierowicz K, Pryszcz L, Navarrete C, Tralle E, Sulej A, Abu NK, Kasprzyk ME, Misztal K, Pateria A, Pakuła A, Bochtler M, Winata C. Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish. Nat Commun. 2022;13:5520. doi:10.1038/s41467-022-33260-6. |