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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma
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Citation:
Blood. 2022;139(15):2316-37. doi:10.1182/blood.2021014011 Epub:
Not Epub Abstract:
The differentiation of B cells into plasmablasts (PBs) and then plasma cells (PCs) is associated with extensive cell... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: Plasmoblasts (PBs) and CD23+ post-activated B cells Citation Extract: Haas M, Caron G, Chatonnet F, Manenti S, Alaterre E, Devin J, Delaloy C, Bertolin G, Viel R, Pignarre A, Llamas-Gutierrez F, Marchalot A, Decaux O, Tarte K, Delpy L, Moreaux J, Fest T. PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma. Blood. 2022;139(15):2316-37. doi:10.1182/blood.2021014011. |
Deciphering the pathogenesis of retinopathy associated with carnitine palmitoyltransferase I deficiency in zebrafish model
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Citation:
Biochem Biophys Res Commun. 2023;664:100-7. doi:10.1016/j.bbrc.2023.04.096 Epub:
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Abstract: Fatty acid oxidation disorders (FAODs) are a group of rare genetic metabolic disorders caused by mutations in genes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ulhaq ZS, Ogino Y, Tse WKF. Deciphering the pathogenesis of retinopathy associated with carnitine palmitoyltransferase I deficiency in zebrafish model. Biochem Biophys Res Commun. 2023;664:100-7. doi:10.1016/j.bbrc.2023.04.096. |
Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish
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Citation:
Sci Adv. 2023 Apr 28;9(17):eade0631. doi: 10.1126/sciadv.ade0631. Epub 2023 Apr 26 Epub:
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We report 21 families displaying neurodevelopmental differences and multiple congenital anomalies while bearing a series of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Patterson V, Ullah F, Bryant L, Griffin JN, Sidhu A, Saliganan S, Blaile M, Saenz MS, Smith R, Ellingwood S, Grange DK, Hu X, Mireguli M, Luo Y, Shen Y, Mulhern M, Zackai E, Ritter A, Izumi K, Hoefele J, Wagner M, Riedhammer KM, Seitz B, Robin NH, Goodloe D, Mignot C, Keren B, Cox H, Jarvis J, Hempel M, Gibson CF, Tran Mau-Them F, Vitobello A, Bruel AL, Sorlin A, Mehta S, Raymond FL, Gilmore K, Powell BC, Weck K, Li C, Vulto-van Silfhout AT, Giacomini T, Mancardi MM, Accogli A, Salpietro V, Zara F, Vora NL, Davis EE, Burdine R, Bhoj E. Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish. Sci Adv. 2023 Apr 28;9(17):eade0631. doi: 10.1126/sciadv.ade0631. Epub 2023 Apr 26. |
Voltage-gated sodium channel activity mediates sea urchin larval skeletal patterning through spatial regulation of Wnt5 expression
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Citation:
Development. 2023 May 4:dev.201460. doi: 10.1242/dev.201460. Online ahead of print Epub:
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Defining pattern formation mechanisms during embryonic development is important for understanding the etiology of birth defects... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Thomas CF, Hawkins DY, Skidanova V, Marrujo SR, Gibson J, Ye Z, Bradham CA. Voltage-gated sodium channel activity mediates sea urchin larval skeletal patterning through spatial regulation of Wnt5 expression. Development. 2023 May 4:dev.201460. doi: 10.1242/dev.201460. Online ahead of print. |
BMP signaling is required to form the anterior neural plate border in ascidian embryos
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Citation:
Dev Genes Evol. 2023;[Epub] doi:10.1007/s00427-023-00702-0 Epub:
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Cranial neurogenic placodes have been considered vertebrate innovations. However, anterior neural plate border (ANB) cells of... Organism or Cell Type:
ascidian Citation Extract: Liu B, Ren X, Satou Y. BMP signaling is required to form the anterior neural plate border in ascidian embryos. Dev Genes Evol. 2023;[Epub] doi:10.1007/s00427-023-00702-0. |
The histone H4K20 methyltransferase SUV4-20H1/KMT5B is required for multiciliated cell differentiation in Xenopus
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Citation:
Life Sci Alliance. 2023 Apr 28;6(7):e202302023. doi: 10.26508/lsa.202302023. Print 2023 Jul Epub:
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H4 lysine 20 dimethylation (H4K20me2) is the most abundant histone modification in vertebrate chromatin. It arises from... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis Citation Extract: Angerilli A, Tait J, Berges J, Shcherbakova I, Pokrovsky D, Schauer T, Smialowski P, Hsam O, Mentele E, Nicetto D, Rupp RA. The histone H4K20 methyltransferase SUV4-20H1/KMT5B is required for multiciliated cell differentiation in Xenopus. Life Sci Alliance. 2023 Apr 28;6(7):e202302023. doi: 10.26508/lsa.202302023. Print 2023 Jul. |
Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex differentiation and reproduction
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Citation:
Biol Res. 2023 Apr 28;56(1):19. doi: 10.1186/s40659-023-00430-9 Epub:
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Background: AMBRA1 is an intrinsically disordered protein, working as a scaffold molecule to coordinate, by protein-protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fontana CM, Terrin F, Facchinello N, Meneghetti G, Dinarello A, Gambarotto L, Zuccarotto A, Caichiolo M, Brocca G, Verin R, Nazio F, Carnevali O, Cecconi F, Bonaldo P, Dalla Valle L. Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex differentiation and reproduction. Biol Res. 2023 Apr 28;56(1):19. doi: 10.1186/s40659-023-00430-9. |
Proprotein Convertase Furin Regulates Melanogenesis via the Notch Signaling Pathway
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Citation:
Discov Med. 2023 Apr 1;35(175):144-156. doi: 10.24976/Discov.Med.202335175.15 Epub:
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Background: Furin is a calcium-dependent serine protease found in almost all mammals. It plays an important role in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Luo L, Jia W, Zhang Y, Guo Y, Zhu J, Li C. Proprotein Convertase Furin Regulates Melanogenesis via the Notch Signaling Pathway. Discov Med. 2023 Apr 1;35(175):144-156. doi: 10.24976/Discov.Med.202335175.15. |
Efficient manipulation of gene expression using Natronobacterium gregoryi Argonaute in zebrafish
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Citation:
BMC Biol. 2023 Apr 24;21(1):95. doi: 10.1186/s12915-023-01599-x Epub:
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Background: Natronobacterium gregoryi Argonaute (NgAgo) was found to reduce mRNA without generating detectable DNA double-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dong Z, Chen X, Zhuo R, Li Y, Zhou Z, Sun Y, Liu Y, Liu M. Efficient manipulation of gene expression using Natronobacterium gregoryi Argonaute in zebrafish. BMC Biol. 2023 Apr 24;21(1):95. doi: 10.1186/s12915-023-01599-x. |
Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in C9ORF72 FTD/ALS
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Citation:
Elife. 2023 Apr 19;12:e85902. doi: 10.7554/eLife.85902. Online ahead of print Epub:
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GGGGCC (G4C2) hexanucleotide repeat expansion in the C9ORF72 gene is the most common genetic cause of frontotemporal dementia (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Parameswaran J, Zhang N, Braems E, Tilahun K, Pant DC, Yin K, Asress S, Heeren K, Banerjee A, Davis E, Schwartz SL, Conn GL, Bassell GJ, Van Den Bosch L, Jiang J. Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in C9ORF72 FTD/ALS. Elife. 2023 Apr 19;12:e85902. doi: 10.7554/eLife.85902. Online ahead of print. |