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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
ftr82 is necessary for hair cell morphogenesis and auditory function during zebrafish development
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Citation:
J Genet Genomics. 2022 Dec 1:S1673-8527(22)00252-1. doi: 10.1016/j.jgg.2022.11.008. Online ahead of print Epub:
Yes Abstract:
Damages of sensory hair cells (HCs) are mainly responsible for sensorineural hearing loss, while the pathological mechanism... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yin G, Qian F, Yao J, Wang Z, Wang X, Liu D, Wang C. ftr82 is necessary for hair cell morphogenesis and auditory function during zebrafish development. J Genet Genomics. 2022 Dec 1:S1673-8527(22)00252-1. doi: 10.1016/j.jgg.2022.11.008. Online ahead of print. |
PPMOs: A Case Study for Cell-Penetrating Peptide Application
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Citation:
In Cell-Penetrating Peptides (eds M. Oba and Y. Demizu). 2023:ch 15. doi:10.1002/9783527835997.ch15 Epub:
Not Epub Abstract:
The current state of the art for in vivo antisense morpholino technology is peptide-conjugated phosphorodiamidate morpholino... Delivery Method:
peptide-linked Citation Extract: Bittner S, Moulton ZX, Moulton HM. PPMOs: A Case Study for Cell-Penetrating Peptide Application. In Cell-Penetrating Peptides (eds M. Oba and Y. Demizu). 2023:ch 15. doi:10.1002/9783527835997.ch15. |
LOF variants identifying candidate genes of laterality defects patients with congenital heart disease
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Citation:
PLoS Genet. 2022;18(12):e1010530. doi:10.1371/journal.pgen.1010530 Epub:
Not Epub Abstract:
Defects in laterality pattern can result in abnormal positioning of the internal organs during the early stages of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu S, Wei W, Wang P, Liu C, Jiang X, Li T, Li F, Wu Y, Chen S, Sun K, Xu R. LOF variants identifying candidate genes of laterality defects patients with congenital heart disease. PLoS Genet. 2022;18(12):e1010530. doi:10.1371/journal.pgen.1010530. |
Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates
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Citation:
Cells. 2022; 11(23):3902. doi:10.3390/cells11233902 Epub:
Not Epub Abstract:
.Attention deficit and hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by alterations in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Faustini G, Longhena F, Muscò A, Bono F, Parrella E, La Via L, Barbon A, Pizzi M, Onofri F, Benfenati F, Missale C, Memo M, Zizioli D, Bellucci A. Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates. Cells. 2022; 11(23):3902. doi:10.3390/cells11233902. |
Viral-induced alternative splicing of host genes promotes influenza replication
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Citation:
Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500 Epub:
Not Epub Abstract:
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here, we show that... Delivery Method:
electroporation Organism or Cell Type:
cell culture: A549 Citation Extract: Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BM, Cherry S, Lynch KW. Viral-induced alternative splicing of host genes promotes influenza replication. Elife. 2020 Dec 3;9:e55500. doi: 10.7554/eLife.55500. |
Transposable elements drive the evolution of metazoan zinc finger genes
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.11.29.518450 Epub:
Not Epub Abstract:
Cys2-His2 Zinc finger genes (ZNFs) form the largest family of transcription factors in metazoans. ZNF evolution is highly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wells JN, Chang N-C, McCormick J, Coleman C, Ramos N, Jin B, Feschotte C. Transposable elements drive the evolution of metazoan zinc finger genes. bioRxiv. 2022;[preprint] doi:10.1101/2022.11.29.518450. |
Parental mutations influence wild-type offspring via transcriptional adaptation
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Citation:
Sci Adv. 2022 Nov 25;8(47):eabj2029. doi: 10.1126/sciadv.abj2029. Epub 2022 Nov 25 Epub:
Not Epub Abstract:
Transgenerational epigenetic inheritance (TEI) is mostly discussed in the context of physiological or environmental factors.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jiang Z, El-Brolosy MA, Serobyan V, Welker JM, Retzer N, Dooley CM, Jakutis G, Juan T, Fukuda N, Maischein HM, Balciunas D, Stainier DYR. Parental mutations influence wild-type offspring via transcriptional adaptation. Sci Adv. 2022 Nov 25;8(47):eabj2029. doi: 10.1126/sciadv.abj2029. Epub 2022 Nov 25. |
Top2a promotes the development of social behavior via PRC2 and H3K27me3
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Citation:
Sci Adv. 2022 Nov 25;8(47):eabm7069. doi: 10.1126/sciadv.abm7069. Epub 2022 Nov 23 Epub:
Not Epub Abstract:
Little is understood about the embryonic development of sociality. We screened 1120 known drugs and found that embryonic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Geng Y, Zhang T, Alonzo IG, Godar SC, Yates C, Pluimer BR, Harrison DL, Nath AK, Yeh JJ, Drummond IA, Bortolato M, Peterson RT. Top2a promotes the development of social behavior via PRC2 and H3K27me3. Sci Adv. 2022 Nov 25;8(47):eabm7069. doi: 10.1126/sciadv.abm7069. Epub 2022 Nov 23. |
Chromosome segregation fidelity requires microtubule polyglutamylation by the cancer downregulated enzyme TTLL11
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Citation:
Nat Commun. 2022 Nov 21;13(1):7147. doi: 10.1038/s41467-022-34909-y Epub:
Not Epub Abstract:
Regulation of microtubule (MT) dynamics is key for mitotic spindle assembly and faithful chromosome segregation. Here we show... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zadra I, Jimenez-Delgado S, Anglada-Girotto M, Segura-Morales C, Compton ZJ, Janke C, Serrano L, Ruprecht V, Vernos I. Chromosome segregation fidelity requires microtubule polyglutamylation by the cancer downregulated enzyme TTLL11. Nat Commun. 2022 Nov 21;13(1):7147. doi: 10.1038/s41467-022-34909-y. |
Microenvironmental Snail1 is a driver of immunosuppression in melanoma
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.11.23.517623 Epub:
Not Epub Abstract:
Melanoma is an aggressive form of skin cancer due to its high metastatic abilities and resistance to therapies. Melanoma cells... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Arumi-Planas M, Rodriguez-Baena FJ, Cabello-Torres F, Gracia F, Lopez-Blau C, Nieto MA, Sanchez-Laorden B. Microenvironmental Snail1 is a driver of immunosuppression in melanoma. bioRxiv. 2022;[preprint] doi:10.1101/2022.11.23.517623 . |