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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction
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Citation:
Development. 2023 Jan 1;150(1):dev201058. doi: 10.1242/dev.201058. Epub 2023 Jan 12 Epub:
Not Epub Abstract:
Many animals achieve sperm chromatin compaction and stabilisation by replacing canonical histones with sperm nuclear basic... Delivery Method:
microinjection Organism or Cell Type:
Hydractinia symbiolongicarpus (cnidarian) Citation Extract: Török A, Browne MJG, Vilar JC, Patwal I, DuBuc TQ, Febrimarsa, Atcheson E, Frank U, Gornik SG, Flaus A. Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction. Development. 2023 Jan 1;150(1):dev201058. doi: 10.1242/dev.201058. Epub 2023 Jan 12. |
C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity
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Citation:
Org Biomol Chem. 2023 Jan 12. doi: 10.1039/d2ob01759h. Online ahead of print Epub:
Not Epub Abstract:
C5-substituted uridine and cytidine morpholino chlorophosphoramidate monomers were synthesized and incorporated into a 12-mer... Citation Extract: Das A, Ghosh A, Sinha S. C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity. Org Biomol Chem. 2023 Jan 12. doi: 10.1039/d2ob01759h. Online ahead of print. |
Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs
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Citation:
Sci Rep. 2023 Jan 11;13(1):94. doi: 10.1038/s41598-022-26614-z Epub:
Not Epub Abstract:
Myotonic dystrophy type 1 (DM1) is caused by expanded CTG repeats (CTGexp) in the dystrophia myotonica protein kinase (DMPK)... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: patient-derived iPSCs differentiated to myotubes Citation Extract: Kawada R, Jonouchi T, Kagita A, Sato M, Hotta A, Sakurai H. Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs. Sci Rep. 2023 Jan 11;13(1):94. doi: 10.1038/s41598-022-26614-z. |
maea affects head formation through ß-catenin degradation during early Xenopus laevis development
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Citation:
Dev Growth Differ. 2022 Nov 28. doi: 10.1111/dgd.12828. Online ahead of print Epub:
Not Epub Abstract:
Canonical Wnt signalling plays important roles in early embryogenesis, such as axis formation due to its activation and head... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Goto T, Shibuya H. maea affects head formation through ß-catenin degradation during early Xenopus laevis development. Dev Growth Differ. 2022 Nov 28. doi: 10.1111/dgd.12828. Online ahead of print. |
Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA
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Citation:
EMBO Rep. 2022 Dec 19:e54350. doi: 10.15252/embr.202154350. Online ahead of print Epub:
Not Epub Abstract:
Stable intronic sequence RNAs (sisRNAs) are stable, long noncoding RNAs containing intronic sequences. While sisRNAs have been... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: MDA-MB-231 and HEK293T Citation Extract: Chan SN, Pek JW. Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA. EMBO Rep. 2022 Dec 19:e54350. doi: 10.15252/embr.202154350. Online ahead of print. |
SCGN deficiency is a risk factor for autism spectrum disorder
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Citation:
Signal Transduct Target Ther. 2023 Jan 2;8(1):3. doi: 10.1038/s41392-022-01225-2 Epub:
Not Epub Abstract:
Autism spectrum disorder (ASD) affects 1-2% of all children and poses a great social and economic challenge for the globe. As a... Organism or Cell Type:
zebrafish Citation Extract: Liu Z, Tan S, Zhou L, Chen L, Liu M, Wang W, Tang Y, Yang Q, Chi S, Jiang P, Zhang Y, Cui Y, Qin J, Hu X, Li S, Liu Q, Chen L, Li S, Burstein E, Li W, Zhang X, Mo X, Jia D. SCGN deficiency is a risk factor for autism spectrum disorder. Signal Transduct Target Ther. 2023 Jan 2;8(1):3. doi: 10.1038/s41392-022-01225-2. |
Morpholino Mediated Gene Editing: A Gene Knockdown Technique Using Translational Blocking Morpholino Oligonucleotides in Single-Celled Cavefish Eggs
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Citation:
JoVE Encyclopedia of Experiments: Biological Techniques. JoVE, Cambridge, MA, (2022?) Epub:
Not Epub Abstract:
paywalled Delivery Method:
microinjection Organism or Cell Type:
cavefish Citation Extract: JoVE staff (?) - this information paywalled. Morpholino Mediated Gene Editing: A Gene Knockdown Technique Using Translational Blocking Morpholino Oligonucleotides in Single-Celled Cavefish Eggs. JoVE Encyclopedia of Experiments: Biological Techniques. JoVE, Cambridge, MA, (2022?). |
Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells
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Citation:
Cell Biosci. 2022 Dec 31;12(1):212. doi: 10.1186/s13578-022-00939-8 Epub:
Not Epub Abstract:
Background: Pathogenic mutations in WRN are a cause of premature aging disease Werner syndrome (WS). Besides accelerated aging... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Leung AO, Yiu TC, Liu L, Tam HY, Gu S, Tu J, Pei D, Cheung HH. Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells. Cell Biosci. 2022 Dec 31;12(1):212. doi: 10.1186/s13578-022-00939-8. |
Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish
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Citation:
PLoS Genet. 2023;19(1):e1010586. doi:10.1371/journal.pgen.1010586 Epub:
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Streptococcus pneumoniae (pneumococcus) is one of the most frequent causes of pneumonia, sepsis and meningitis in humans, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Saralahti AK, Harjula S-KE, Rantapero T, Uusi-Mäkelä MIE, Kaasinen M, Junno M, Piippo H, Nykter M, Lohi O, Rounioja S, Parikka M, Rämet M. Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish. PLoS Genet. 2023;19(1):e1010586. doi:10.1371/journal.pgen.1010586. |
α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish
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Citation:
Cells. 2022 Dec 29;12(1):144. doi: 10.3390/cells12010144 Epub:
Not Epub Abstract:
Glycosylation is an important mechanism regulating various biological processes, including intercellular signaling and adhesion... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hayashiji N, Kawahara G, Xu X, Fukuda T, Kerever A, Gu J, Hayashi YK, Arikawa-Hirasawa E. α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish. Cells. 2022 Dec 29;12(1):144. doi: 10.3390/cells12010144. |