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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
Differential cellular stiffness across tissues that contribute to Xenopus neural tube closure
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Citation:
Dev Growth Differ. 2024 Jun 26. doi: 10.1111/dgd.12936. Epub ahead of print. PMID: 38925637 Epub:
Not Epub Abstract:
During the formation of the neural tube, the primordium of the vertebrate central nervous system, the actomyosin activity of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Suzuki M, Yasue N, Ueno N. Differential cellular stiffness across tissues that contribute to Xenopus neural tube closure. Dev Growth Differ. 2024 Jun 26. doi: 10.1111/dgd.12936. Epub ahead of print. PMID: 38925637. |
U4 snRNP inhibits premature cleavage and polyadenylation of pre-mRNAs
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Citation:
Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2406710121. doi: 10.1073/pnas.2406710121. Epub 2024 Jun 25. PMID: 38917004 Epub:
Not Epub Abstract:
The essential role of U4 snRNP in pre-messenger RNA (mRNA) splicing has been well established. In this study, we utilized an... Organism or Cell Type:
cell culture: HeLa Citation Extract: Feng Q, Zhao D, Lin Z, Li M, Xiang AP, Ye C, Yao C. U4 snRNP inhibits premature cleavage and polyadenylation of pre-mRNAs. Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2406710121. doi: 10.1073/pnas.2406710121. Epub 2024 Jun 25. PMID: 38917004. |
Survival among patients receiving eteplirsen for up to 8 years for the treatment of Duchenne muscular dystrophy and contextualization with natural history controls
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Citation:
Muscle Nerve. 2024 Jul;70(1):60-70. doi: 10.1002/mus.28075. Epub 2024 Mar 14. PMID: 38482981 Epub:
Not Epub Abstract:
Eteplirsen, approved in the US for patients with Duchenne muscular dystrophy (DMD) with exon 51 skip-amenable variants, is... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Iff J, Done N, Tuttle E, Zhong Y, Wei F, Darras BT, McDonald CM, Mercuri E, Muntoni F. Survival among patients receiving eteplirsen for up to 8 years for the treatment of Duchenne muscular dystrophy and contextualization with natural history controls. Muscle Nerve. 2024 Jul;70(1):60-70. doi: 10.1002/mus.28075. Epub 2024 Mar 14. PMID: 38482981. |
Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells
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Citation:
PLoS One. 2024 Jun 28;19(6):e0304557. doi: 10.1371/journal.pone.0304557. eCollection 2024. PMID: 38941348 Epub:
Not Epub Abstract:
Prenatal alcohol exposure (PAE) causes cognitive impairment and a distinctive craniofacial dysmorphology, due in part to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Flentke GR, Wilkie TE, Baulch J, Huang Y, Smith SM. Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells. PLoS One. 2024 Jun 28;19(6):e0304557. doi: 10.1371/journal.pone.0304557. eCollection 2024. PMID: 38941348. |
Increased Netrin downstream of overactive Hedgehog signaling disrupts optic fissure formation
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Citation:
Dev Dyn. 2024 Aug 21. doi: 10.1002/dvdy.733. Online ahead of print. PMID: 39166841 Epub:
Not Epub Abstract:
Background
Uveal coloboma, a developmental eye defect, is caused by failed development of the optic fissure, a ventral... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lusk S, LaPotin S, Presnell JS, Kwan KM. Increased Netrin downstream of overactive Hedgehog signaling disrupts optic fissure formation. Dev Dyn. 2024 Aug 21. doi: 10.1002/dvdy.733. Online ahead of print. PMID: 39166841. |
3-Hydroxykynurenine targets kainate receptors to promote defense against infection
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Citation:
Nat Chem Biol. 2024 Jun 19. doi: 10.1038/s41589-024-01635-z. Epub ahead of print. PMID: 38898166 Epub:
Not Epub Abstract:
Bacterial infection involves a complex interaction between the pathogen and host where the outcome of infection is not solely... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Parada-Kusz M, Clatworthy AE, Goering ER, Blackwood SM, Shigeta JY, Mashin E, Salm EJ, Choi C, Combs S, Lee JSW, Rodriguez-Osorio C, Clish C, Tomita S, Hung DT. 3-Hydroxykynurenine targets kainate receptors to promote defense against infection. Nat Chem Biol. 2024 Jun 19. doi: 10.1038/s41589-024-01635-z. Epub ahead of print. PMID: 38898166. |
CCSer2 gates dynein activity at the cell periphery
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Citation:
J Cell Biol. 2025 Jun 2;224(6):e202406153. doi: 10.1083/jcb.202406153. Epub 2025 Apr 22. PMID: 40261303; PMCID: PMC12013514 Epub:
Not Epub Abstract:
Cytoplasmic dynein-1 (dynein) is a microtubule-associated, minus end-directed motor that traffics hundreds of different cargos... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zang JL, Gibson D, Zheng AM, Shi W, Gillies JP, Stein C, Drerup CM, DeSantis ME. CCSer2 gates dynein activity at the cell periphery. J Cell Biol. 2025 Jun 2;224(6):e202406153. doi: 10.1083/jcb.202406153. Epub 2025 Apr 22. PMID: 40261303; PMCID: PMC12013514. |
Cytokines IL-1β and IL-10 are required for Müller glia proliferation following light damage in the adult zebrafish retina
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Citation:
Front. Cell Dev. Biol., 13 June 2024. Sec. Molecular and Cellular Pathology. Volume 12 - 2024 Epub:
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Zebrafish possess the ability to regenerate dying neurons in response to retinal injury, with both Müller glia and microglia... Delivery Method:
intravitreal injection and electroporation Organism or Cell Type:
zebrafish Citation Extract: Lu C & Hyde DR. Cytokines IL-1β and IL-10 are required for Müller glia proliferation following light damage in the adult zebrafish retina. Front. Cell Dev. Biol., 13 June 2024. Sec. Molecular and Cellular Pathology. Volume 12 - 2024. |
Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions
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Citation:
EMBO J. 2024 Jun 17. doi: 10.1038/s44318-024-00142-0. Epub ahead of print. PMID: 38886581 Epub:
Not Epub Abstract:
Endothelial cell responses to fluid shear stress from blood flow are crucial for vascular development, function, and disease. A... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tanaka K, Chen M, Prendergast A, Zhuang Z, Nasiri A, Joshi D, Hintzen J, Chung M, Kumar A, Mani A, Koleske A, Crawford J, Nicoli S, Schwartz MA. Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctions. EMBO J. 2024 Jun 17. doi: 10.1038/s44318-024-00142-0. Epub ahead of print. PMID: 38886581. |
A β-catenin chromobody-based probe highlights endothelial maturation during vascular morphogenesis in vivo
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Citation:
Development. 2024 Jun 1;151(11):dev202122. doi: 10.1242/dev.202122. Epub 2024 Jun 7. PMID: 38847494. Epub:
Not Epub Abstract:
Visualization of protein dynamics is a crucial step in understanding cellular processes. Chromobodies, fluorescently labelled... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gauvrit S, Zhao S, Rothbauer U, Stainier DYR. A β-catenin chromobody-based probe highlights endothelial maturation during vascular morphogenesis in vivo. Development. 2024 Jun 1;151(11):dev202122. doi: 10.1242/dev.202122. Epub 2024 Jun 7. PMID: 38847494.. |