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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Analysis of incidental findings in Qatar genome participants reveals novel functional variants in LMNA and DSP

Authors:
Elfatih A, Da'as SI, Abdelrahman D, Mbarek H, Mohammed I, Hasan W, Fakhro KA; The Qatar Genome Program Research Consortium; Estivill X, Mifsud B
Citation:
Hum Mol Genet. 2022 Aug 23;31(16):2796-2809. doi: 10.1093/hmg/ddac073
Epub:
Not Epub
Abstract:
In order to report clinically actionable incidental findings in genetic testing, the American College of Medical Genetics and...
Link:
https://academic.oup.com/hmg/article/31/16/2796/6554582
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elfatih A, Da'as SI, Abdelrahman D, Mbarek H, Mohammed I, Hasan W, Fakhro KA; The Qatar Genome Program Research Consortium; Estivill X, Mifsud B. Analysis of incidental findings in Qatar genome participants reveals novel functional variants in LMNA and DSP. Hum Mol Genet. 2022 Aug 23;31(16):2796-2809. doi: 10.1093/hmg/ddac073.

Gold nanoparticles conjugated DNA-tile nanomaterials for simultaneous delivery of morpholino antisense oligonucleotides and doxorubicin

Authors:
Tunc CU, Culha M
Citation:
J Drug Deliv Sci Technol. 2022;74:103546. doi:10.1016/j.jddst.2022.103546
Epub:
Not Epub
Abstract:
Current therapies have limited treatment effect on cancer. Combinational delivery of multiple therapeutics has been commonly...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1773224722004579
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: breast cancer
Citation Extract:
Tunc CU, Culha M. Gold nanoparticles conjugated DNA-tile nanomaterials for simultaneous delivery of morpholino antisense oligonucleotides and doxorubicin. J Drug Deliv Sci Technol. 2022;74:103546. doi:10.1016/j.jddst.2022.103546.

Nucleolar URB1 ensures 3′ ETS rRNA removal to prevent exosome surveillance

Authors:
Shan L, Xu G, Yao R-W, Luan P-F, Huang Y, Zhang P-H, Pan Y-H, Zhang L, Gao X, Li Y, Cao S-M, Gao S-X, Yang Z-H, Li S, Yang L-Z, Wang Y, Wong CCL, Yu L, Li J, Yang L, Chen L-L
Citation:
Nature. 2023;[Epub ahead of orint]. doi:10.1038/s41586-023-05767-5
Epub:
Not Epub
Abstract:
The nucleolus is the most prominent membraneless condensate in the nucleus. It comprises hundreds of proteins with distinct...
Link:
https://www.nature.com/articles/s41586-023-05767-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shan L, Xu G, Yao R-W, Luan P-F, Huang Y, Zhang P-H, Pan Y-H, Zhang L, Gao X, Li Y, Cao S-M, Gao S-X, Yang Z-H, Li S, Yang L-Z, Wang Y, Wong CCL, Yu L, Li J, Yang L, Chen L-L. Nucleolar URB1 ensures 3′ ETS rRNA removal to prevent exosome surveillance. Nature. 2023;[Epub ahead of orint]. doi:10.1038/s41586-023-05767-5.

Mucociliary Wnt signaling promotes cilia biogenesis and beating

Authors:
Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C
Citation:
Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2
Epub:
Not Epub
Abstract:
It is widely thought that Wnt/Lrp6 signaling proceeds through the cytoplasm and that motile cilia are signaling-inert...
Link:
https://www.nature.com/articles/s41467-023-36743-2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C. Mucociliary Wnt signaling promotes cilia biogenesis and beating. Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2.

Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis

Authors:
Murayama E, Vivier C, Schmidt A, Herbomel P
Citation:
Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y
Epub:
Not Epub
Abstract:
Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC...
Link:
https://www.nature.com/articles/s41467-023-36612-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Murayama E, Vivier C, Schmidt A, Herbomel P. Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis. Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y.

Migration and establishment of progenitor pool of melanocytes is governed by SEMA3E-PLXND1 signaling

Authors:
Subramaniam Y, Sharma B, Aggarwal A, Raja DA, Gupta I, Ghazi M, Sivasubbu S, Natarajan VT
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.02.28.530560
Epub:
Not Epub
Abstract:
Vertebrate pigmentation is an outcome of an interplay of several signaling pathways that result in immense diversity of pigment...
Link:
https://www.biorxiv.org/content/10.1101/2023.02.28.530560v1.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Subramaniam Y, Sharma B, Aggarwal A, Raja DA, Gupta I, Ghazi M, Sivasubbu S, Natarajan VT. Migration and establishment of progenitor pool of melanocytes is governed by SEMA3E-PLXND1 signaling. bioRxiv. 2023;[preprint] doi:10.1101/2023.02.28.530560 .

Temporal single-cell transcriptomic analysis of the sox1a:eGFP transgenic line identified the lateral floor plate progenitor cells as the origin of intraspinal serotonergic neurons

Authors:
Chen F, Köhler M, Cucun G, Takamiya M, Kizil C, Cosacak MI, Rastegar S
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.01.530240
Epub:
Not Epub
Abstract:
The Sox family of transcription factors plays a crucial role in the development of the vertebrate nervous system. In the...
Link:
https://www.biorxiv.org/content/10.1101/2023.03.01.530240v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen F, Köhler M, Cucun G, Takamiya M, Kizil C, Cosacak MI, Rastegar S. Temporal single-cell transcriptomic analysis of the sox1a:eGFP transgenic line identified the lateral floor plate progenitor cells as the origin of intraspinal serotonergic neurons. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.01.530240.

Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia

Authors:
Kim J, Park EA, Shin MY, Park SJ
Citation:
Microbiol Spectr. 2023 Mar 6:e0491922. doi: 10.1128/spectrum.04919-22. Online ahead of print
Epub:
Not Epub
Abstract:
Cyclin-dependent kinases (CDKs) are serine/threonine kinases that control the eukaryotic cell cycle. Limited information is...
Link:
https://journals.asm.org/doi/10.1128/spectrum.04919-22
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Kim J, Park EA, Shin MY, Park SJ. Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia. Microbiol Spectr. 2023 Mar 6:e0491922. doi: 10.1128/spectrum.04919-22. Online ahead of print.

YULINK regulates vascular formation in zebrafish and HUVECs

Authors:
Lin HH, Kuo MW, Fan TC, Yu AL, Yu J
Citation:
Biol Res. 2023;56(7). doi:10.1186/s40659-023-00415-8
Epub:
Not Epub
Abstract:
Background: The distinct arterial and venous cell fates are dictated by a combination of various genetic factors which form...
Link:
https://biolres.biomedcentral.com/articles/10.1186/s40659-023-00415-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin HH, Kuo MW, Fan TC, Yu AL, Yu J. YULINK regulates vascular formation in zebrafish and HUVECs. Biol Res. 2023;56(7). doi:10.1186/s40659-023-00415-8.

In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery

Authors:
Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL
Citation:
ACS Chem Biol. 2023 Mar 1. doi: 10.1021/acschembio.2c00920. Online ahead of print
Epub:
Yes
Abstract:
Peptide-mediated delivery of macromolecules in cells has significant potential therapeutic benefits, but no therapy employing...
Link:
https://pubs.acs.org/doi/10.1021/acschembio.2c00920
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL. In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery. ACS Chem Biol. 2023 Mar 1. doi: 10.1021/acschembio.2c00920. Online ahead of print.

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