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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation
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Citation:
Nat Commun. 2023 Apr 15;14(1):2157. doi: 10.1038/s41467-023-37928-5 Epub:
Not Epub Abstract:
Hirschsprung disease is characterized by the absence of enteric neurons caused by the defects of enteric neural crest cells,... Delivery Method:
Endo-Porter PEG Organism or Cell Type:
cell culture: Hirschsprung disease enteric neural crest cells (HSCR-ENCC) from iPSCs Citation Extract: Li Z, Lui KN, Lau ST, Lai FP, Li P, Chung PH, Wong KK, Tam PK, Garica-Barcelo MM, Hui CC, Sham PC, Ngan ES. Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation. Nat Commun. 2023 Apr 15;14(1):2157. doi: 10.1038/s41467-023-37928-5. |
Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.04.15.537039 Epub:
Not Epub Abstract:
The nephron, functional unit of the vertebrate kidney, is specialized in metabolic wastes excretion and body fluids... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Cervino AS, Collodel MG, Lopez IA, Hochbaum D, Hukriede NA, Cirio MC. Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation. bioRxiv. 2023;[preprint] doi:10.1101/2023.04.15.537039. |
Production of sterile Atlantic salmon by germ cell ablation with antisense oligonucleotides
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Citation:
bioRxiv;[preprint] doi:10.1101/2023.04.14.536849 Epub:
Not Epub Abstract:
Cultivation of sterile-only fish in aquaculture offers multiple benefits of environmental, economical, and social value. A... Delivery Method:
microinjection Organism or Cell Type:
Salmo salar (Atlantic salmon) Citation Extract: Tveiten H, Andersen Ø, Swain JK, Johnsen H, Mommens M, Slanchev K. Production of sterile Atlantic salmon by germ cell ablation with antisense oligonucleotides. bioRxiv;[preprint] doi:10.1101/2023.04.14.536849. |
Systemic administration of the antisense oligonucleotide NS-089/NCNP-02 for skipping of exon 44 in patients with Duchenne muscular dystrophy: Study protocol for a phase I/II clinical trial
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Citation:
Neuropsychopharmacol Rep. 2023 Jun;43(2):277-286. doi: 10.1002/npr2.12335. Epub 2023 Apr 3. Epub:
Not Epub Abstract:
Aim: The purpose of this study is to evaluate the safety and pharmacokinetics of the novel morpholino oligomer NS-089/NCNP-02... Delivery Method:
intravenous (i.v.) Organism or Cell Type:
human Citation Extract: Ishizuka T, Komaki H, Asahina Y, Nakamura H, Motohashi N, Takeshita E, Motohashi Y, Ishiyama A, Yonee C, Maruyama S, Hida E, Aoki Y. Systemic administration of the antisense oligonucleotide NS-089/NCNP-02 for skipping of exon 44 in patients with Duchenne muscular dystrophy: Study protocol for a phase I/II clinical trial. Neuropsychopharmacol Rep. 2023 Jun;43(2):277-286. doi: 10.1002/npr2.12335. Epub 2023 Apr 3.. |
Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation
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Citation:
Nat Commun. 2023 Apr 13;14(1):2115. doi: 10.1038/s41467-023-37745-w Epub:
Not Epub Abstract:
The metameric pattern of somites is created based on oscillatory expression of clock genes in presomitic mesoderm. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yabe T, Uriu K, Takada S. Ripply suppresses Tbx6 to induce dynamic-to-static conversion in somite segmentation. Nat Commun. 2023 Apr 13;14(1):2115. doi: 10.1038/s41467-023-37745-w. |
TAR Syndrome-associated Rbm8a deficiency causes hematopoietic defects and attenuates Wnt/PCP signaling
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.04.12.536513 Epub:
Not Epub Abstract:
Defects in blood development frequently occur among syndromic congenital anomalies. Thrombocytopenia-Absent Radius (TAR)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kocere A, Chiavacci E, Méndez-Acevedo KM, Soneson C, Hiltabidle MS, MacGowan JS, Panáková D, Williams MLK, Robinson MD, Mosimann C, Burger A. TAR Syndrome-associated Rbm8a deficiency causes hematopoietic defects and attenuates Wnt/PCP signaling. bioRxiv. 2023;[preprint] doi:10.1101/2023.04.12.536513 . |
Screening of Drosophila microRNA-degradation sequences reveals Argonaute1 mRNA's role in regulating miR-999
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Citation:
Nat Commun. 2023 Apr 13;14(1):2108. doi: 10.1038/s41467-023-37819-9 Epub:
Not Epub Abstract:
MicroRNAs (miRNA) load onto AGO proteins to target mRNAs for translational repression or degradation. However, miRNA... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: Drosophila S2 Citation Extract: Sheng P, Li L, Li T, Wang Y, Hiers NM, Mejia JS, Sanchez JS, Zhou L, Xie M. Screening of Drosophila microRNA-degradation sequences reveals Argonaute1 mRNA's role in regulating miR-999. Nat Commun. 2023 Apr 13;14(1):2108. doi: 10.1038/s41467-023-37819-9. |
A Realistic Mixture of Persistent Organic Pollutants Affects Zebrafish Development, Behavior, and Specifically Eye Formation by Inhibiting the Condensin I Complex
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Citation:
Toxics. 2023;11(4):357. doi:10.3390/toxics11040357 Epub:
Not Epub Abstract:
Persistent organic pollutants (POPs) are posing major environmental and health threats due to their stability, ubiquity, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guerrero-Limón G, Nivelle R, Bich-Ngoc N, Duy-Thanh D, Muller M. A Realistic Mixture of Persistent Organic Pollutants Affects Zebrafish Development, Behavior, and Specifically Eye Formation by Inhibiting the Condensin I Complex. Toxics. 2023;11(4):357. doi:10.3390/toxics11040357. |
Zebrafish dnm1a gene plays a role in the formation of axons and synapses in the nervous tissue
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Citation:
J Neurosci Res. 2023 Apr 9. doi: 10.1002/jnr.25197. Online ahead of print Epub:
Yes Abstract:
Classical dynamins (DNMs) are GTPase proteins engaged in endocytosis, a fundamental process for cargo internalization from the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bragato C, Pistocchi A, Bellipanni G, Confalonieri S, Balciunie J, Monastra FM, Carra S, Vitale G, Mantecca P, Cotelli F, Gaudenzi G. Zebrafish dnm1a gene plays a role in the formation of axons and synapses in the nervous tissue. J Neurosci Res. 2023 Apr 9. doi: 10.1002/jnr.25197. Online ahead of print. |
Enhancement of zebrafish sperm production via a large body-sized surrogate with germ cell transplantation
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Citation:
Commun Biol. 2023 Apr 14;6(1):412. doi: 10.1038/s42003-023-04800-7 Epub:
Not Epub Abstract:
Zebrafish (Danio rerio) is a commonly-used vertebrate model species for many research areas. However, its low milt volume... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nayak R, Franěk R, Šindelka R, Pšenička M.. Enhancement of zebrafish sperm production via a large body-sized surrogate with germ cell transplantation. Commun Biol. 2023 Apr 14;6(1):412. doi: 10.1038/s42003-023-04800-7. |