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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects
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Citation:
PLoS Genet. 2023;19(8):e1010873. doi:10.1371/journal.pgen.1010873 Epub:
Not Epub Abstract:
Aberrantly up-regulated activity of the type II transmembrane protease Matriptase-1 has been associated with the development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hatzold J, Nett V, Brantsch S, Zhang J-L, Armistead J, Wessendorf H, Stephens R, Humbert RO, Iden S, Hammerschmidt M. Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects. PLoS Genet. 2023;19(8):e1010873. doi:10.1371/journal.pgen.1010873. |
[Prickle planar cell polarity protein 1 involved in the pathogenesis of skeletal class Ⅲ malocclusion]
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Citation:
Zhonghua Kou Qiang Yi Xue Za Zhi. 2023 Aug 3;58(8):799-808. doi: 10.3760/cma.j.cn112144-20230404-00135. Online ahead of print Epub:
Not Epub Abstract:
Objective: To explore the mechanisms of prickle planar cell polarity protein 1 (PRICKLE1) involved in the occurrence of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang CC, Ma L, Zhou X, Fan LW, Pan YC. [Prickle planar cell polarity protein 1 involved in the pathogenesis of skeletal class Ⅲ malocclusion]. Zhonghua Kou Qiang Yi Xue Za Zhi. 2023 Aug 3;58(8):799-808. doi: 10.3760/cma.j.cn112144-20230404-00135. Online ahead of print. |
Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping
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Citation:
Mol Ther Nucleic Acids. 2024 May 24;35(3):102228. doi: 10.1016/j.omtn.2024.102228. eCollection 2024 Sep 10. PMID: 38975000 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a progressive muscle disease caused by the absence of dystrophin protein. One current DMD... Delivery Method:
intramuscular (i.m.) injection Organism or Cell Type:
mice Citation Extract: McCormack NM, Calabrese KA, Sun CM, Tully CB, Heier CR, Fiorillo AA. Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping. Mol Ther Nucleic Acids. 2024 May 24;35(3):102228. doi: 10.1016/j.omtn.2024.102228. eCollection 2024 Sep 10. PMID: 38975000. |
Neuronal migration prevents spatial competition in retinal morphogenesis
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Citation:
Nature. 2023:[Epub ahead of print]. doi:10.1038/s41586-023-06392-y Epub:
Yes Abstract:
The concomitant occurrence of tissue growth and organization is a hallmark of organismal development. This often means that... Organism or Cell Type:
zebrafish Citation Extract: Rocha-Martins M, Nerli E, Kretzschmar J, Weigert M, Icha J, Myers EW, Norden C. Neuronal migration prevents spatial competition in retinal morphogenesis. Nature. 2023:[Epub ahead of print]. doi:10.1038/s41586-023-06392-y. |
Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos
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Citation:
Nat Commun. 2023;14:4807. doi:10.1038/s41467-023-40496-3 Epub:
Not Epub Abstract:
Somatic cell nuclear transfer (SCNT) can be used to reprogram differentiated somatic cells to a totipotent state but has poor... Delivery Method:
microinjection Organism or Cell Type:
mouse zygote Citation Extract: Xu R, Zhu Q, Zhao Y, Chen M, Yang L, Shen S, Yang G, Shi Z, Zhang X, Shi Q, Kou X, Zhao Y, Wang H, Jiang C, Li C, Gao S, Liu X. Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos. Nat Commun. 2023;14:4807. doi:10.1038/s41467-023-40496-3. |
An integeative GWAS followed by functional investigation reveals possible involvement of CNTNAP5 in glaucomatous neurodegeneration
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Citation:
J Neurochem. Poster Sessions A. 2023;166: 30-88. Poster 3A. doi:10.1111/jnc.15896 Epub:
Not Epub Abstract:
Primary angle closure glaucoma (PACG) is one of the major leading causes of blindness. In India, ~30% of people show a narrow... Organism or Cell Type:
zebrafish Citation Extract: Chakraborty S, Roy SS, Sarma J, Das S, Saha S, Bhattacharjee S, Acharya M. An integeative GWAS followed by functional investigation reveals possible involvement of CNTNAP5 in glaucomatous neurodegeneration. J Neurochem. Poster Sessions A. 2023;166: 30-88. Poster 3A. doi:10.1111/jnc.15896. |
Ribo-On and Ribo-Off tools using a self-cleaving ribozyme allow manipulation of endogenous gene expression in C. elegans
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Citation:
Commun Biol. 2023;6:816. doi:10.1038/s42003-023-05184-4 Epub:
Not Epub Abstract:
Investigating gene function relies on the efficient manipulation of endogenous gene expression. Currently, a limited number of... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Caenorhabditis elegans (roundworm) Citation Extract: Fang J, Wang J, Wang Y, Liu X, Chen B, Zou W. Ribo-On and Ribo-Off tools using a self-cleaving ribozyme allow manipulation of endogenous gene expression in C. elegans. Commun Biol. 2023;6:816. doi:10.1038/s42003-023-05184-4. |
The endosomal escape vehicle platform enhances delivery of oligonucleotides in preclinical models of neuromuscular disorders
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Citation:
Mol Ther Nucleic Acids. 2023 Jun 29;33:273-285. doi: 10.1016/j.omtn.2023.06.022. eCollection 2023 Sep 12 Epub:
Not Epub Abstract:
Biological therapeutic agents are highly targeted and potent but limited in their ability to reach intracellular targets. These... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Li X, Kheirabadi M, Dougherty PG, Kamer KJ, Shen X, Estrella NL, Peddigari S, Pathak A, Blake SL, Sizensky E, Genio CD, Gaur AB, Dhanabal M, Girgenrath M, Sethuraman N, Qian Z. The endosomal escape vehicle platform enhances delivery of oligonucleotides in preclinical models of neuromuscular disorders. Mol Ther Nucleic Acids. 2023 Jun 29;33:273-285. doi: 10.1016/j.omtn.2023.06.022. eCollection 2023 Sep 12. |
Convergent synthesis of phosphorodiamidate morpholino oligonucleotides (PMOs) by the H-phosphonate approach
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Citation:
Sci Rep. 2023;13:12576. doi:10.1038/s41598-023-38698-2 Epub:
Not Epub Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMOs) are a promising type of antisense oligonucleotides, but their challenging... Citation Extract: Tsurusaki T, Sato K, Imai H, Hirai K, Takahashi D, Wada T. Convergent synthesis of phosphorodiamidate morpholino oligonucleotides (PMOs) by the H-phosphonate approach. Sci Rep. 2023;13:12576. doi:10.1038/s41598-023-38698-2. |
Alternative splicing of CEACAM1 by hypoxia-inducible factor-1α enhances tolerance to hepatic ischemia in mice and humans
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Citation:
Sci Transl Med. 2023 Aug 2;15(707):eadf2059. doi: 10.1126/scitranslmed.adf2059. Epub 2023 Aug 2. PMID: 37531413 Epub:
Not Epub Abstract:
Although alternative splicing (AS) drives transcriptional responses and cellular adaptation to environmental stresses, its... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Dery KJ, Kojima H, Kageyama S, Kadono K, Hirao H, Cheng B, Zhai Y, Farmer DG, Kaldas FM, Yuan X, Eltzschig HK, Kupiec-Weglinski JW. Alternative splicing of CEACAM1 by hypoxia-inducible factor-1α enhances tolerance to hepatic ischemia in mice and humans. Sci Transl Med. 2023 Aug 2;15(707):eadf2059. doi: 10.1126/scitranslmed.adf2059. Epub 2023 Aug 2. PMID: 37531413. |