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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation
Citation:
J Med Genet. 2023 Apr 3:jmg-2022-108888. doi: 10.1136/jmg-2022-108888. Online ahead of print Epub:
Not Epub Abstract:
Background: Although retinitis pigmentosa (RP) is the most common type of hereditary retinal dystrophy, approximately 25%-45%... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kong L, Chu G, Ma W, Liang J, Liu D, Liu Q, Wei X, Jia S, Gu H, He Y, Luo W, Cao S, Zhou X, He R, Yuan Z. Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation. J Med Genet. 2023 Apr 3:jmg-2022-108888. doi: 10.1136/jmg-2022-108888. Online ahead of print. |
Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via p53 and JAK2-STAT3 Signaling
Citation:
Biology. 2023; 12(4):538. https://doi.org/10.3390/biology12040538 Epub:
Not Epub Abstract:
Ribosomes are the vital molecular machine for protein translation in a cell. Defects in several nucleolar proteins have been... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liang F, Lu X, Wu B, Yang Y, Qin W. Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via p53 and JAK2-STAT3 Signaling. Biology. 2023; 12(4):538. https://doi.org/10.3390/biology12040538. |
Poly- and Perfluoroalkyl Substances Induce Immunotoxicity via the TLR Pathway in Zebrafish: Links to Carbon Chain Length
Citation:
Environ Sci Technol. 2023;57(15): 6139–49. doi:10.1021/acs.est.2c09716. Online ahead of print Epub:
Not Epub Abstract:
Previous studies have reported the immunotoxicity of per- and polyfluoroalkyl substances (PFASs), but it remains a significant... Organism or Cell Type:
zebrafish Citation Extract: Tang L, Qiu W, Zhang S, Wang J, Yang X, Xu B, Magnuson JT, Xu EG, Wu M, Zheng C. Poly- and Perfluoroalkyl Substances Induce Immunotoxicity via the TLR Pathway in Zebrafish: Links to Carbon Chain Length. Environ Sci Technol. 2023;57(15): 6139–49. doi:10.1021/acs.est.2c09716. Online ahead of print. |
BDNF signaling in correlation-dependent structural plasticity in the developing visual system
Citation:
PLoS Biol. 2023;21(4):e3002070. doi:10.1371/journal.pbio.3002070 Epub:
Not Epub Abstract:
During development, patterned neural activity instructs topographic map refinement. Axons with similar patterns of neural... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kutsarova E, Schohl A, Munz M, Wang A, Zhang YY, Bilash OM, Ruthazer ES. BDNF signaling in correlation-dependent structural plasticity in the developing visual system. PLoS Biol. 2023;21(4):e3002070. doi:10.1371/journal.pbio.3002070. |
Abnormal autophagy is a critical mechanism in TANGO2-related rhabdomyolysis
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.29.534583 Epub:
Not Epub Abstract:
Patients with pathogenic variants in the TANGO2 gene suffer from severe and recurrent rhabdomyolysis (RM) episodes precipitated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Montealegre S, de Calbiac H, Straube M, Debruge H, Chentout L, Ciura S, Imbard A, Le Guillou E, Marian A, Goudin N, Caccavelli L, Fabrega S, Hubas A, van Endert P, Dupont N, Diana J, Kabashi E, de Lonlay P. Abnormal autophagy is a critical mechanism in TANGO2-related rhabdomyolysis. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.29.534583. |
Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation
Citation:
eLife. 2023;12:e83652. doi:10.7554/eLife.83652 Epub:
Not Epub Abstract:
Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Buglak DB, Bougaran P, Kulikauskas MR, Liu Z, Monaghan-Benson E, Gold AL, Marvin AP, Burciu A, Tanke NT, Oatley M, Ricketts SN, Kinghorn K, Johnson BN, Shiau CE, Rogers S, Guilluy C, Bautch VL. Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation. eLife. 2023;12:e83652. doi:10.7554/eLife.83652. |
Inhibition of Interferon Alpha by a Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer Increases Influenza Virus Replication in Chicken Embryo Fibroblast (DF-1) Cells; An Alternative Strategy to Increasing Vaccine Production in Cell Culture
Citation:
SSRN. 2022:[preprint] doi:10.2139/ssrn.4057449 Epub:
Not Epub Abstract:
Influenza is a global health issue causing substantial health and economic burdens in affected populations. Routine, annual... Citation Extract: Prescott M, Moulton H, Pastey M. Inhibition of Interferon Alpha by a Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer Increases Influenza Virus Replication in Chicken Embryo Fibroblast (DF-1) Cells; An Alternative Strategy to Increasing Vaccine Production in Cell Culture. SSRN. 2022:[preprint] doi:10.2139/ssrn.4057449. |
Her6 and Prox1 are novel regulators of photoreceptor regeneration in the zebrafish retina
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.20.532714 Epub:
Not Epub Abstract:
Damage to light-sensing photoreceptors (PRs) occurs in highly prevalent retinal diseases. As humans cannot regenerate new PRs,... Delivery Method:
retinal microinjection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Veen K, Krylov A, Yu S, He J, Boyd P, Hyde DR, Mantamadiotis T, Cheng LY, Jusuf PR. Her6 and Prox1 are novel regulators of photoreceptor regeneration in the zebrafish retina. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.20.532714. |
In Vivo Evaluation of Exon 51 Skipping in hDMD/Dmd-null Mice
Citation:
Methods Mol Biol. 2023;2640:327-336. doi: 10.1007/978-1-0716-3036-5_23. PMID: 36995605 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a fatal X-linked condition that affects 1 in 3500-6000 newborn boys a year. An out-of-... Delivery Method:
intravenous (i.v.) and intramuscular (i.m.) injections Organism or Cell Type:
mice Citation Extract: Sheri N, Yokota T. In Vivo Evaluation of Exon 51 Skipping in hDMD/Dmd-null Mice. Methods Mol Biol. 2023;2640:327-336. doi: 10.1007/978-1-0716-3036-5_23. PMID: 36995605. |
Exons 45-55 Skipping Using Antisense Oligonucleotides in Immortalized Human DMD Muscle Cells
Citation:
Methods Mol Biol. 2023;2640:313-325. doi: 10.1007/978-1-0716-3036-5_22. Epub:
Not Epub Abstract:
Antisense oligonucleotides (AOs) have demonstrated high potential as a therapy for treating genetic diseases like Duchene... Organism or Cell Type:
cell culture: immortalized DMD muscle cell lines Citation Extract: He M, Yokota T. Exons 45-55 Skipping Using Antisense Oligonucleotides in Immortalized Human DMD Muscle Cells. Methods Mol Biol. 2023;2640:313-325. doi: 10.1007/978-1-0716-3036-5_22.. |