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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Mob4 is required for neurodevelopment in zebrafish
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Citation:
microPublication Biology. 2023. 10.17912/micropub.biology.000762 Epub:
Not Epub Abstract:
Mob4 is an essential evolutionary conserved protein shown to play roles in cell division and neural development. Mob4 is a core... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Florindo C, Mimoso JM, Palma SL, Gonçalves C, Silvestre D, Campinho M, Tavares A. Mob4 is required for neurodevelopment in zebrafish. microPublication Biology. 2023. 10.17912/micropub.biology.000762. |
U1 AMO (antisense morpholino oligo) disrupts U1 snRNP structure to promote intronic premature cleavage and polyadenylation (PCPA)
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.02.24.529985 Epub:
Not Epub Abstract:
Functional depletion of U1 snRNP with a 25 nt U1 AMO (antisense morpholino oligonucleotides) may lead to intronic premature... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Feng Q, Lin Z, Deng Y, Ran Y, Xiang AP, Ye C, Yao C. U1 AMO (antisense morpholino oligo) disrupts U1 snRNP structure to promote intronic premature cleavage and polyadenylation (PCPA). bioRxiv. 2023;[preprint] doi:10.1101/2023.02.24.529985. |
Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish
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Citation:
Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2102569120. doi: 10.1073/pnas.2102569120. Epub 2023 Feb 21 Epub:
Not Epub Abstract:
In the human genome, about 750 genes contain one intron excised by the minor spliceosome. This spliceosome comprises its own... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Khatri D, Putoux A, Cologne A, Kaltenbach S, Besson A, Bertiaux E, Guguin J, Fendler A, Dupont MA, Benoit-Pilven C, Qebibo L, Ahmed-Elie S, Audebert-Bellanger S, Blanc P, Rambaud T, Castelle M, Cornen G, Grotto S, Guët A, Guibaud L, Michot C, Odent S, Ruaud L, Sacaze E, Hamel V, Bordonné R, Leutenegger AL, Edery P, Burglen L, Attié-Bitach T, Mazoyer S, Delous M. Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2102569120. doi: 10.1073/pnas.2102569120. Epub 2023 Feb 21. |
Quantifying endothelial cell proliferation in the zebrafish embryo
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Citation:
F1000Res. 2021 Oct 11;10:1032. doi: 10.12688/f1000research.73130.1. eCollection 2021 Epub:
Not Epub Abstract:
Introduction: Endothelial cell (EC) proliferation is a fundamental determinant of vascular development and homeostasis, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bowley G, Chico TJ, Serbanovic-Canic J, Evans PC. Quantifying endothelial cell proliferation in the zebrafish embryo. F1000Res. 2021 Oct 11;10:1032. doi: 10.12688/f1000research.73130.1. eCollection 2021. |
Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.02.19.529123 Epub:
Not Epub Abstract:
CD20-directed immunotherapies, such as rituximab, are mainstays of clinical management of mature B-cell neoplasms, previously... Delivery Method:
electroporation of standard Morpholino; Vivo-Morpholino Organism or Cell Type:
cell culture: OCI-Ly8, Raji and MEC-1 Citation Extract: Ang Z, Hayer KE, Diz MT, Schmidt C, Zheng S, Xu F, Falkenstein CD, Loftus JP, Yang SY, Asnani M, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Schuster SJ, Thomas-Tikhonenko A. Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. bioRxiv. 2023;[preprint] doi:10.1101/2023.02.19.529123. |
Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney
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Citation:
Cells. 2023 Feb 20;12(4):666. doi:10.3390/cells12040666 Epub:
Not Epub Abstract:
Despite significant advances in understanding nephron segment patterning, many questions remain about the underlying genes and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wesselman HM, Gatz AE, Pfaff MR, Arceri L, Wingert RA. Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney. Cells. 2023 Feb 20;12(4):666. doi:10.3390/cells12040666. |
USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling
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Citation:
Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7 Epub:
Not Epub Abstract:
The Wnt-β-catenin signal transduction pathway is essential for embryonic development and adult tissue homeostasis. Wnt... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. |
FGF8 rescues motor deficits in zebrafish model of limb-girdle muscular dystrophy R18
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Citation:
Biochem Biophys Res Commun. 2023 Feb 19;652:76-83. doi: 10.1016/j.bbrc.2023.02.046. Online ahead of print Epub:
Not Epub Abstract:
Variants in the gene encoding trafficking protein particle complex 11 (TRAPPC11) cause limb-girdle muscular dystrophy R18 (LGMD... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ulhaq ZS, Ogino Y, Tse WKF. FGF8 rescues motor deficits in zebrafish model of limb-girdle muscular dystrophy R18. Biochem Biophys Res Commun. 2023 Feb 19;652:76-83. doi: 10.1016/j.bbrc.2023.02.046. Online ahead of print. |
TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease
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Citation:
Nat Commun. 2023 Feb 23;14(1):1009. doi: 10.1038/s41467-023-36277-7 Epub:
Not Epub Abstract:
Mutations in the mitochondrial or nuclear genomes are associated with a diverse group of human disorders characterized by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Van Haute L, O'Connor E, Díaz-Maldonado H, Munro B, Polavarapu K, Hock DH, Arunachal G, Athanasiou-Fragkouli A, Bardhan M, Barth M, Bonneau D, Brunetti-Pierri N, Cappuccio G, Caruana NJ, Dominik N, Goel H, Helman G, Houlden H, Lenaers G, Mention K, Murphy D, Nandeesh B, Olimpio C, Powell CA, Preethish-Kumar V, Procaccio V, Rius R, Rebelo-Guiomar P, Simons C, Vengalil S, Zaki MS, Ziegler A, Thorburn DR, Stroud DA, Maroofian R, Christodoulou J, Gustafsson C, Nalini A, Lochmüller H, Minczuk M, Horvath R. TEFM variants impair mitochondrial transcription causing childhood-onset neurological disease. Nat Commun. 2023 Feb 23;14(1):1009. doi: 10.1038/s41467-023-36277-7. |
Neurogenin 2 and Neuronal Differentiation 1 Control Proper Development of the Chick Trigeminal Ganglion and Its Nerve Branches
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Citation:
J Dev Biol. 2023 Feb 19;11(1):8. doi: 10.3390/jdb11010008 Epub:
Not Epub Abstract:
The trigeminal ganglion contains the cell bodies of sensory neurons comprising cranial nerve V, which relays information... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Bina P, Hines MA, Sanyal J, Taneyhill LA. Neurogenin 2 and Neuronal Differentiation 1 Control Proper Development of the Chick Trigeminal Ganglion and Its Nerve Branches. J Dev Biol. 2023 Feb 19;11(1):8. doi: 10.3390/jdb11010008. |