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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling-dependent neurogenesis in the embryonic neural tube
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Citation:
Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2220037120. doi: 10.1073/pnas.2220037120. Epub 2023 May 30 Epub:
Not Epub Abstract:
The balance between neural stem cell proliferation and neuronal differentiation is paramount for the appropriate development of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Shim S, Goyal R, Panoutsopoulos AA, Balashova OA, Lee D, Borodinsky LN. Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling-dependent neurogenesis in the embryonic neural tube. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2220037120. doi: 10.1073/pnas.2220037120. Epub 2023 May 30. |
Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound
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Citation:
Pharmaceutics. 2023 Jun 6;15(6):1665. doi: 10.3390/pharmaceutics15061665 Epub:
Not Epub Abstract:
Strategies for gene and nucleic acid delivery to skeletal muscles have been extensively explored to treat Duchenne muscular... Delivery Method:
nanobubbles and ultrasound Organism or Cell Type:
mice Citation Extract: Sekine S, Mayama S, Nishijima N, Kojima T, Endo-Takahashi Y, Ishii Y, Shiono H, Akiyama S, Sakurai A, Sashida S, Hamano N, Tada R, Suzuki R, Maruyama K, Negishi Y. Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound. Pharmaceutics. 2023 Jun 6;15(6):1665. doi: 10.3390/pharmaceutics15061665. |
Jak2 and Jaw Muscles Are Required for Buccopharyngeal Membrane Perforation during Mouth Development
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Citation:
J Dev Biol. 2023 May 31;11(2):24. doi: 10.3390/jdb11020024 Epub:
Not Epub Abstract:
The mouth is a central feature of our face, without which we could not eat, breathe, or communicate. A critical and early event... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Dickinson AJG. Jak2 and Jaw Muscles Are Required for Buccopharyngeal Membrane Perforation during Mouth Development. J Dev Biol. 2023 May 31;11(2):24. doi: 10.3390/jdb11020024. |
Mitochondrial calcium signaling mediated transcriptional regulation of keratin filaments is a critical determinant of melanogenesis
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.05.26.542250 Epub:
Not Epub Abstract:
Mitochondria are versatile organelles that regulate several physiological functions. Many mitochondria-controlled processes are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tanwar J, Ahuja K, Sharma A, Sehgal P, Ranjan G, Sultan F, Priya A, Venkatesan M, Yenamandra VK, Singh A, Madesh M, Sivasubbu S, Motiani RK. Mitochondrial calcium signaling mediated transcriptional regulation of keratin filaments is a critical determinant of melanogenesis. bioRxiv. 2023;[preprint] doi:10.1101/2023.05.26.542250. |
Directionality of developing skeletal muscles is set by mechanical forces
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Citation:
Nat Commun. 2023 May 27;14(1):3060. doi: 10.1038/s41467-023-38647-7 Epub:
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Formation of oriented myofibrils is a key event in musculoskeletal development. However, the mechanisms that drive myocyte... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sunadome K, Erickson AG, Kah D, Fabry B, Adori C, Kameneva P, Faure L, Kanatani S, Kaucka M, Dehnisch Ellström I, Tesarova M, Zikmund T, Kaiser J, Edwards S, Maki K, Adachi T, Yamamoto T, Fried K, Adameyko I. Directionality of developing skeletal muscles is set by mechanical forces. Nat Commun. 2023 May 27;14(1):3060. doi: 10.1038/s41467-023-38647-7. |
Esrrγa regulates nephron and ciliary development by controlling prostaglandin synthesis
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Citation:
Development. 2023 May 15;150(10):dev201411. doi: 10.1242/dev.201411. Epub 2023 May 26 Epub:
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Cilia are essential for the ontogeny and function of many tissues, including the kidney. Here, we report that transcription... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wesselman HM, Flores-Mireles AL, Bauer A, Pei L, Wingert RA. Esrrγa regulates nephron and ciliary development by controlling prostaglandin synthesis. Development. 2023 May 15;150(10):dev201411. doi: 10.1242/dev.201411. Epub 2023 May 26. |
Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2
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Citation:
BMC Mol Cell Biol. 2023 May 26;24(1):20. doi: 10.1186/s12860-023-00483-4 Epub:
Not Epub Abstract:
Background: DYX1C1 (DNAAF4) and DCDC2 are two of the most replicated dyslexia candidate genes in genetic studies. They both... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bieder A, Chandrasekar G, Wason A, Erkelenz S, Gopalakrishnan J, Kere J, Tapia-Páez I. Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2. BMC Mol Cell Biol. 2023 May 26;24(1):20. doi: 10.1186/s12860-023-00483-4. |
Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation
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Citation:
Biochem Biophys Res Commun. 2023 Jun 19;673:9-15. doi: 10.1016/j.bbrc.2023.06.058. Online ahead of print Epub:
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Nephronophthisis (NPH), an autosomal recessive ciliopathy, results from mutations in more than 20 different genes (NPHPs).... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang H, Zaiser F, Eckert P, Ruf J, Kayser N, Veenstra AC, Müller M, Haas R, Walz G, Yakulov TA. Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation. Biochem Biophys Res Commun. 2023 Jun 19;673:9-15. doi: 10.1016/j.bbrc.2023.06.058. Online ahead of print. |
Etv5a suppresses neural progenitor cell proliferation by inhibiting sox2 transcription
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Citation:
Stem Cells Dev. 2023 Jun 26. doi: 10.1089/scd.2023.0005. Online ahead of print Epub:
Yes Abstract:
Neural progenitor cells are self-renewable, proliferative, and multipotent cell populations that generate diverse types of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shih HY, Chen HY, Huang YC, Yeh TH, Chen YC, Cheng YC. Etv5a suppresses neural progenitor cell proliferation by inhibiting sox2 transcription. Stem Cells Dev. 2023 Jun 26. doi: 10.1089/scd.2023.0005. Online ahead of print. |
Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.05.24.542079 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a progressive and fatal muscle degenerating disease caused by dystrophin deficiency.... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: healthy and DMD myotubes Citation Extract: Hariharan S, Lorintiu O, Lee C-C, Duchemin-Pelletier E, Li X, Healy A, Doyonnas R, Selig L, Poydenot P, Ventre E, Weston A, Owens J, Christoforou N. Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients. bioRxiv. 2023;[preprint] doi:10.1101/2023.05.24.542079. |