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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12351 scientific papers returned from the database with the search filters currently being used below.

Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation

Authors:
Pan H-C, Lo K-C, Wang Y-H, Huang H-T, Cheng S-C, Sun C-Y, Chen Y-H
Citation:
Fishes. 2023;8(9):440.doi:10.3390/fishes8090440
Epub:
Not Epub
Abstract:
(1) Background: Klotho is a multifunctional protein, but its biophysiological roles during fish early development are unclear...
Link:
https://www.mdpi.com/2410-3888/8/9/440
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pan H-C, Lo K-C, Wang Y-H, Huang H-T, Cheng S-C, Sun C-Y, Chen Y-H. Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation. Fishes. 2023;8(9):440.doi:10.3390/fishes8090440.

DRAM1 confers resistance to Salmonella infection

Authors:
Masud S, Xie J, Grijmans BJM, van der Kooij S, Zhang R, Prajsnar TK, Meijer AH
Citation:
Autophagy Rep. 2023;2(1):2242715. doi:10.1080/27694127.2023.2242715
Epub:
Not Epub
Abstract:
DRAM1 is an infection inducible autophagy modulator, previously shown to promote autophagic and lysosomal defense responses...
Link:
https://www.tandfonline.com/doi/full/10.1080/27694127.2023.2242715
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Masud S, Xie J, Grijmans BJM, van der Kooij S, Zhang R, Prajsnar TK, Meijer AH. DRAM1 confers resistance to Salmonella infection. Autophagy Rep. 2023;2(1):2242715. doi:10.1080/27694127.2023.2242715.

Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome

Authors:
Blue EE, White JJ, Dush MK, Gordon WW, Wyatt BH, White P, Marvin CT, Helle E, Ojala T, Priest JR, Jenkins MM, Almli LM, Reefhuis J, Pangilinan F, Brody LC, McBride KL, Garg V, Shaw GM, Romitti PA, Nembhard WN, Browne ML, Werler MM, Kay DM, Mital S, Chong JX, Nascone-Yoder NM, Bamshad MJ
Citation:
Hum Genet Genom Adv. 2023;4(4):100232. doi:10.1016/j.xhgg.2023.100232
Epub:
Not Epub
Abstract:
Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect (CHD) characterized by hypoplasia of the left...
Link:
https://www.cell.com/cms/10.1016/j.xhgg.2023.100232/attachment/21afb3a1-a16f-418d-9d4a-525c460d1bd8/mmc1.pdf
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Blue EE, White JJ, Dush MK, Gordon WW, Wyatt BH, White P, Marvin CT, Helle E, Ojala T, Priest JR, Jenkins MM, Almli LM, Reefhuis J, Pangilinan F, Brody LC, McBride KL, Garg V, Shaw GM, Romitti PA, Nembhard WN, Browne ML, Werler MM, Kay DM, Mital S, Chong JX, Nascone-Yoder NM, Bamshad MJ . Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome. Hum Genet Genom Adv. 2023;4(4):100232. doi:10.1016/j.xhgg.2023.100232.

Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy

Authors:
Karolczak S, Deshwar AR, Aristegui E, Kamath BM, Lawlor MW, Andreoletti G, Volpatti JR, Ellis JL, Yin C, Dowling JJ
Citation:
J Clin Invest. 2023 Jul 25:e166275. doi: 10.1172/JCI166275. Online ahead of print
Epub:
Yes
Abstract:
X-linked myotubular myopathy (XLMTM) is a fatal congenital disorder caused by mutations in the MTM1 gene. Currently, there are...
Link:
https://www.jci.org/articles/view/166275
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Karolczak S, Deshwar AR, Aristegui E, Kamath BM, Lawlor MW, Andreoletti G, Volpatti JR, Ellis JL, Yin C, Dowling JJ. Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy. J Clin Invest. 2023 Jul 25:e166275. doi: 10.1172/JCI166275. Online ahead of print.

Paracrine regulation of neural crest EMT by placodal MMP28

Authors:
Gouignard N, Bibonne A, Mata JF, Bajanca F, Berki B, Barriga EH, Saint-Jeannet JP, Theveneau E
Citation:
PLoS Biol. 2023 Aug 17;21(8):e3002261. doi: 10.1371/journal.pbio.3002261. Online ahead of print
Epub:
Not Epub
Abstract:
Epithelial–mesenchymal transition (EMT) is an early event in cell dissemination from epithelial tissues. EMT endows cells with...
Link:
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002261
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gouignard N, Bibonne A, Mata JF, Bajanca F, Berki B, Barriga EH, Saint-Jeannet JP, Theveneau E. Paracrine regulation of neural crest EMT by placodal MMP28. PLoS Biol. 2023 Aug 17;21(8):e3002261. doi: 10.1371/journal.pbio.3002261. Online ahead of print.

“Plod2” a Lysyl Hydroxylase Required for HSC Specification

Authors:
Khoury H, Clements W
Citation:
Exp. Hematol. 2023;124 supplement:S101. doi:10.1016/j.exphem.2023.06.209
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) are self-renewing precursors that continuously renew hematopoietic lineages during life and...
Link:
https://www.exphem.org/article/S0301-472X(23)01483-2/pdf
Organism or Cell Type:
zebrafish
Citation Extract:
Khoury H, Clements W. “Plod2” a Lysyl Hydroxylase Required for HSC Specification. Exp. Hematol. 2023;124 supplement:S101. doi:10.1016/j.exphem.2023.06.209.

Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons

Authors:
Fu CY, Chen HY, Lin CY, Chen SJ, Sheu JC, Tsai HJ
Citation:
Commun Biol. 2023 Aug 15;6(1):849. doi: 10.1038/s42003-023-05223-0
Epub:
Not Epub
Abstract:
Understanding the molecular interaction between ligand and receptor is important for providing the basis for the development of...
Link:
https://www.nature.com/articles/s42003-023-05223-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fu CY, Chen HY, Lin CY, Chen SJ, Sheu JC, Tsai HJ. Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons. Commun Biol. 2023 Aug 15;6(1):849. doi: 10.1038/s42003-023-05223-0.

Ontogenetically distinct neutrophils differ in function and transcriptional profile in zebrafish

Authors:
García-López JP, Grimaldi A, Chen Z, Meneses C, Bravo-Tello K, Bresciani E, Banderas A, Burgess SM, Hernández PP, Feijoo CG
Citation:
Nat Commun. 2023 Aug 15;14(1):4942. doi: 10.1038/s41467-023-40662-7
Epub:
Not Epub
Abstract:
The current view of hematopoiesis considers leukocytes on a continuum with distinct developmental origins, and which exert non-...
Link:
https://www.nature.com/articles/s41467-023-40662-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
García-López JP, Grimaldi A, Chen Z, Meneses C, Bravo-Tello K, Bresciani E, Banderas A, Burgess SM, Hernández PP, Feijoo CG. Ontogenetically distinct neutrophils differ in function and transcriptional profile in zebrafish. Nat Commun. 2023 Aug 15;14(1):4942. doi: 10.1038/s41467-023-40662-7.

Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle

Authors:
Pollitt EJG, Sánchez-Posada J, Snashall CM, Derrick CJ, Noël ES
Citation:
Development. 2024 Jul 1;151(13):dev202482. doi: 10.1242/dev.202482. Epub 2024 Jun 28. PMID: 38940292.
Epub:
Not Epub
Abstract:
During heart development, the embryonic ventricle becomes enveloped by the epicardium, which adheres to the outer apical...
Link:
https://journals.biologists.com/dev/article/151/13/dev202482/358952/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pollitt EJG, Sánchez-Posada J, Snashall CM, Derrick CJ, Noël ES. Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle. Development. 2024 Jul 1;151(13):dev202482. doi: 10.1242/dev.202482. Epub 2024 Jun 28. PMID: 38940292..

Lymphocyte pathway analysis using naturally lymphocyte-deficient fish

Authors:
Zhang G, Swann J, Felder M, O'Meara C, Boehm T
Citation:
Eur J Immunol. 2023 Aug 18:e2350577. doi: 10.1002/eji.202350577. Online ahead of print
Epub:
Yes
Abstract:
Comparative phylogenetic analyses are of potential value to establish the essential components of genetic networks underlying...
Link:
https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.202350577
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang G, Swann J, Felder M, O'Meara C, Boehm T. Lymphocyte pathway analysis using naturally lymphocyte-deficient fish. Eur J Immunol. 2023 Aug 18:e2350577. doi: 10.1002/eji.202350577. Online ahead of print.

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