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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

The Male-Biased Expression of miR-2954 Is Involved in the Male Pathway of Chicken Sex Differentiation

Authors:
Cheng Y, Zhang Z, Zhang G, Chen L, Zeng C, Liu X, Feng Y
Citation:
Cells. 2022 Dec 20;12(1):4. doi: 10.3390/cells12010004
Epub:
Not Epub
Abstract:
Many expression data showed miRNAs have a potential function on regulating gonadal differentiation in animals, but their...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Cheng Y, Zhang Z, Zhang G, Chen L, Zeng C, Liu X, Feng Y. The Male-Biased Expression of miR-2954 Is Involved in the Male Pathway of Chicken Sex Differentiation. Cells. 2022 Dec 20;12(1):4. doi: 10.3390/cells12010004.

Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier

Authors:
Jonusaite S, Oulhen N, Izumi Y, Furuse M, Yamamoto T, Sakamoto N, Wessel G, Heyland A
Citation:
Dev Biol. 2022 Dec 29;495:21-34. doi: 10.1016/j.ydbio.2022.12.007. Online ahead of print
Epub:
Not Epub
Abstract:
Septate junctions (SJs) evolved as cell-cell junctions that regulate the paracellular barrier and integrity of epithelia in...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Jonusaite S, Oulhen N, Izumi Y, Furuse M, Yamamoto T, Sakamoto N, Wessel G, Heyland A. Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier. Dev Biol. 2022 Dec 29;495:21-34. doi: 10.1016/j.ydbio.2022.12.007. Online ahead of print.

Ste20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes

Authors:
Song K, Jiang X, Xu X, Chen Y, Zhang J, Tian Y, Wang Q, Weng J, Liang Y, Ma W
Citation:
Cell Prolif. 2022 Dec 29:e13391. doi: 10.1111/cpr.13391. Online ahead of print
Epub:
Not Epub
Abstract:
Ste20-like kinase (SLK) is involved in cell proliferation and migration in somatic cells. This study aims to explore SLK...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Song K, Jiang X, Xu X, Chen Y, Zhang J, Tian Y, Wang Q, Weng J, Liang Y, Ma W. Ste20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes. Cell Prolif. 2022 Dec 29:e13391. doi: 10.1111/cpr.13391. Online ahead of print.

Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development

Authors:
Li W, Wen L, Rathod B, Gingras AC, Ley K, Lee HS
Citation:
Life Sci Alliance. 2022 Dec 27;6(3):e202201800. doi: 10.26508/lsa.202201800. Print 2023 Mar
Epub:
Not Epub
Abstract:
Direct contact between cells expressing either ephrin ligands or Eph receptor tyrosine kinase produces diverse developmental...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li W, Wen L, Rathod B, Gingras AC, Ley K, Lee HS. Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development. Life Sci Alliance. 2022 Dec 27;6(3):e202201800. doi: 10.26508/lsa.202201800. Print 2023 Mar.

Nuclear-cytoplasmic compartmentalization of cyclin B1-Cdk1 promotes robust timing of mitotic events

Authors:
Maryu G, Yang Q
Citation:
Cell Rep. 2022 Dec 27;41(13):111870. doi: 10.1016/j.celrep.2022.111870
Epub:
Not Epub
Abstract:
The cyclin-dependent kinase (Cdk1) oscillator is widely characterized in homogenized cytosolic extracts, leaving unclear the...
Delivery Method:
mixing into cycling egg extracts in microemulsion droplets
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Maryu G, Yang Q. Nuclear-cytoplasmic compartmentalization of cyclin B1-Cdk1 promotes robust timing of mitotic events. Cell Rep. 2022 Dec 27;41(13):111870. doi: 10.1016/j.celrep.2022.111870.

Lasp1 Expression Is Implicated in Embryonic Development of Zebrafish

Authors:
Grossi I, Schiavone M, Cannone E, Grejdan OA, Tobia C, Bonomini F, Rezzani R, Salvi A, De Petro G
Citation:
Genes. 2023;14(1):35. doi:10.3390/genes14010035
Epub:
Not Epub
Abstract:
The LIM and SH3 domain protein 1 (LASP1) was originally identified in metastatic breast cancer and mainly characterized as a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grossi I, Schiavone M, Cannone E, Grejdan OA, Tobia C, Bonomini F, Rezzani R, Salvi A, De Petro G. Lasp1 Expression Is Implicated in Embryonic Development of Zebrafish. Genes. 2023;14(1):35. doi:10.3390/genes14010035.

Functional screening of congenital heart disease risk loci identifies 5 genes essential for heart development in zebrafish

Authors:
Ma J, Gu Y, Liu J, Song J, Zhou T, Jiang M, Wen Y, Guo X, Zhou Z, Sha J, He J, Hu Z, Luo L, Liu M
Citation:
Cell Mol Life Sci. 2022 Dec 27;80(1):19. doi: 10.1007/s00018-022-04669-5
Epub:
Not Epub
Abstract:
Congenital heart disease (CHD) is the most common birth defect worldwide and a main cause of perinatal and infant mortality....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma J, Gu Y, Liu J, Song J, Zhou T, Jiang M, Wen Y, Guo X, Zhou Z, Sha J, He J, Hu Z, Luo L, Liu M. Functional screening of congenital heart disease risk loci identifies 5 genes essential for heart development in zebrafish. Cell Mol Life Sci. 2022 Dec 27;80(1):19. doi: 10.1007/s00018-022-04669-5.

Phosphorylation of adducin-1 by TPX2 promotes interpolar microtubule homeostasis and precise chromosome segregation in mouse oocytes

Authors:
Zhang Y, Fan B, Li X, Tang Y, Shao J, Liu L, Ren Y, Yang Y, Xu B
Citation:
Cell Biosci. 2022 Dec 20;12(1):205. doi: 10.1186/s13578-022-00943-y
Epub:
Not Epub
Abstract:
Background: ADD1 (adducin-1) and TPX2 (targeting protein for Xklp2) are centrosomal proteins and regulate mitotic spindle...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Zhang Y, Fan B, Li X, Tang Y, Shao J, Liu L, Ren Y, Yang Y, Xu B. Phosphorylation of adducin-1 by TPX2 promotes interpolar microtubule homeostasis and precise chromosome segregation in mouse oocytes. Cell Biosci. 2022 Dec 20;12(1):205. doi: 10.1186/s13578-022-00943-y.

Evaluation of Cardiovascular Toxicity of Folic Acid and 6S-5-Methyltetrahydrofolate-Calcium in Early Embryonic Development

Authors:
Lian Z, Wu Z, Gu R, Wang Y, Wu C, Cheng Z, He M, Wang Y, Cheng Y, Gu HF
Citation:
Cells. 2022 Dec 7;11(24):3946. doi: 10.3390/cells11243946
Epub:
Not Epub
Abstract:
Folic acid (FA) is a synthetic and highly stable version of folate, while 6S-5-methyltetrahydrofolate is the predominant form...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lian Z, Wu Z, Gu R, Wang Y, Wu C, Cheng Z, He M, Wang Y, Cheng Y, Gu HF. Evaluation of Cardiovascular Toxicity of Folic Acid and 6S-5-Methyltetrahydrofolate-Calcium in Early Embryonic Development. Cells. 2022 Dec 7;11(24):3946. doi: 10.3390/cells11243946.

Synthesis of 5′-Thiol Functionalized Morpholino Oligo-Nucleotide and Subsequent Conjugation with IGT to Improve Delivery and Antisense Efficacy In Vitro

Authors:
Ghosh U, Gupta S, Sinha S
Citation:
Bioconjugate Chem. 2023;34(1):174-80 doi:10.1021/acs.bioconjchem.2c00587
Epub:
Not Epub
Abstract:
Thiol functionalized oligonucleotides are useful intermediates for a wide range of applications including DNA nanobiotechnology...
Delivery Method:
IGT-linked
Organism or Cell Type:
cell culture: MCF7
Citation Extract:
Ghosh U, Gupta S, Sinha S. Synthesis of 5′-Thiol Functionalized Morpholino Oligo-Nucleotide and Subsequent Conjugation with IGT to Improve Delivery and Antisense Efficacy In Vitro. Bioconjugate Chem. 2023;34(1):174-80 doi:10.1021/acs.bioconjchem.2c00587.

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