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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

Authors:
Sebastian-Perez R, Nakagawa S, Tu X, Aranda S, Pesaresi M, Gomez-Garcia PA, Alcoverro-Bertran M, Gomez-Vazquez JL, Carnevali D, Borràs E, Sabidó E, Martin L, Nissim-Rafinia M, Meshorer E, Neguembor MV, Croce LD. Cosma MP
Citation:
eLife. 2023;12:RP87742 doi:10.7554/eLife.87742.1
Epub:
Not Epub
Abstract:
Chromocenters are established after the 2-cell (2C) stage during mouse embryonic development, but the factors that mediate...
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Sebastian-Perez R, Nakagawa S, Tu X, Aranda S, Pesaresi M, Gomez-Garcia PA, Alcoverro-Bertran M, Gomez-Vazquez JL, Carnevali D, Borràs E, Sabidó E, Martin L, Nissim-Rafinia M, Meshorer E, Neguembor MV, Croce LD. Cosma MP. SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state. eLife. 2023;12:RP87742 doi:10.7554/eLife.87742.1.

A spatiotemporal barrier formed by Follistatin is required for left-right patterning

Authors:
Fu XX, Zhuo DH, Zhang YJ, Li YF, Liu X, Xing YY, Huang Y, Wang YF, Cheng T, Wang D, Chen SH, Chen YJ, Jiang GN, Lu FI, Feng Y, Huang X, Ma J, Liu W, Bai G, Xu PF
Citation:
Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2219649120. doi: 10.1073/pnas.2219649120. Epub 2023
Epub:
Not Epub
Abstract:
How left-right (LR) asymmetry emerges in a patterning field along the anterior-posterior axis remains an unresolved problem in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fu XX, Zhuo DH, Zhang YJ, Li YF, Liu X, Xing YY, Huang Y, Wang YF, Cheng T, Wang D, Chen SH, Chen YJ, Jiang GN, Lu FI, Feng Y, Huang X, Ma J, Liu W, Bai G, Xu PF. A spatiotemporal barrier formed by Follistatin is required for left-right patterning. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2219649120. doi: 10.1073/pnas.2219649120. Epub 2023.

Fusobacterium nucleatum dissemination by neutrophils

Authors:
Ellett F, Kacamak NI, Alvarez CR, Oliveira EHS, Hasturk H, Paster BJ, Kantarci A, Irimia D
Citation:
J Oral Microbiol. 2023 Jun 4;15(1):2217067. doi: 10.1080/20002297.2023.2217067. eCollection 2023
Epub:
Not Epub
Abstract:
Recent studies uncovered that Fusobacterium nucleatum (Fn), a common, opportunistic bacterium in the oral cavity, is associated...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ellett F, Kacamak NI, Alvarez CR, Oliveira EHS, Hasturk H, Paster BJ, Kantarci A, Irimia D. Fusobacterium nucleatum dissemination by neutrophils. J Oral Microbiol. 2023 Jun 4;15(1):2217067. doi: 10.1080/20002297.2023.2217067. eCollection 2023.

Transcriptome analysis reveals an Atoh1b-dependent gene set downstream of Dlx3b/4b during early inner ear development in zebrafish

Authors:
Ezhkova D, Schwarzer S, Spieß S, Geffarth M, Machate A, Zöller D, Stucke J, Alexopoulou D, Lesche M, Dahl A, Hans S
Citation:
Biol Open. 2023 Jun 15;12(6):bio059911. doi: 10.1242/bio.059911. Epub 2023 Jun 5
Epub:
Not Epub
Abstract:
The vertebrate inner ear is the sensory organ mediating hearing and balance. The entire organ develops from the otic placode,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ezhkova D, Schwarzer S, Spieß S, Geffarth M, Machate A, Zöller D, Stucke J, Alexopoulou D, Lesche M, Dahl A, Hans S. Transcriptome analysis reveals an Atoh1b-dependent gene set downstream of Dlx3b/4b during early inner ear development in zebrafish. Biol Open. 2023 Jun 15;12(6):bio059911. doi: 10.1242/bio.059911. Epub 2023 Jun 5.

Overlapping Targets of Shh and Gata3 during Craniofacial Development

Authors:
Kar RD, Eberhart JK
Citation:
Res Sq. 2023 Jun 12:rs.3.rs-2973064 [preprint]. doi:10.21203/rs.3.rs-2973064/v1
Epub:
Not Epub
Abstract:
Background Congenital birth defects are among the leading causes of infant mortality. Phenotypic variation in these defects...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kar RD, Eberhart JK. Overlapping Targets of Shh and Gata3 during Craniofacial Development. Res Sq. 2023 Jun 12:rs.3.rs-2973064 [preprint]. doi:10.21203/rs.3.rs-2973064/v1.

Role of maternal spiralian-specific homeobox gene SPILE-E in the specification of blastomeres along the animal-vegetal axis during the early cleavage stages of mollusks

Authors:
Morino Y, Yoshikawa H
Citation:
Dev Growth Differ. 2023 Jul 1. doi: 10.1111/dgd.12874. Online ahead of print
Epub:
Yes
Abstract:
Spiralians, one of the major clades of bilaterians, share a unique development known as spiralian development, characterized by...
Delivery Method:
microinjection
Organism or Cell Type:
Nipponacmea fuscoviridis (limpet)
Citation Extract:
Morino Y, Yoshikawa H. Role of maternal spiralian-specific homeobox gene SPILE-E in the specification of blastomeres along the animal-vegetal axis during the early cleavage stages of mollusks. Dev Growth Differ. 2023 Jul 1. doi: 10.1111/dgd.12874. Online ahead of print.

Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex

Authors:
Katahira J, Ohmae T, Yasugi M, Sasaki R, Itoh Y, Kohda T, Hieda M, Yokota Hirai M, Okamoto T, Miyamoto Y
Citation:
Nucleic Acids Res. 2023 Jun 1:gkad483. doi: 10.1093/nar/gkad483. Online ahead of print
Epub:
Yes
Abstract:
To facilitate selfish replication, viruses halt host gene expression in various ways. The nuclear export of mRNA is one such...
Organism or Cell Type:
cell culture: 293F_Nsp14_wt2
Citation Extract:
Katahira J, Ohmae T, Yasugi M, Sasaki R, Itoh Y, Kohda T, Hieda M, Yokota Hirai M, Okamoto T, Miyamoto Y. Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex. Nucleic Acids Res. 2023 Jun 1:gkad483. doi: 10.1093/nar/gkad483. Online ahead of print.

Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling-dependent neurogenesis in the embryonic neural tube

Authors:
Shim S, Goyal R, Panoutsopoulos AA, Balashova OA, Lee D, Borodinsky LN
Citation:
Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2220037120. doi: 10.1073/pnas.2220037120. Epub 2023 May 30
Epub:
Not Epub
Abstract:
The balance between neural stem cell proliferation and neuronal differentiation is paramount for the appropriate development of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shim S, Goyal R, Panoutsopoulos AA, Balashova OA, Lee D, Borodinsky LN. Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling-dependent neurogenesis in the embryonic neural tube. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2220037120. doi: 10.1073/pnas.2220037120. Epub 2023 May 30.

Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound

Authors:
Sekine S, Mayama S, Nishijima N, Kojima T, Endo-Takahashi Y, Ishii Y, Shiono H, Akiyama S, Sakurai A, Sashida S, Hamano N, Tada R, Suzuki R, Maruyama K, Negishi Y
Citation:
Pharmaceutics. 2023 Jun 6;15(6):1665. doi: 10.3390/pharmaceutics15061665
Epub:
Not Epub
Abstract:
Strategies for gene and nucleic acid delivery to skeletal muscles have been extensively explored to treat Duchenne muscular...
Delivery Method:
nanobubbles and ultrasound
Organism or Cell Type:
mice
Citation Extract:
Sekine S, Mayama S, Nishijima N, Kojima T, Endo-Takahashi Y, Ishii Y, Shiono H, Akiyama S, Sakurai A, Sashida S, Hamano N, Tada R, Suzuki R, Maruyama K, Negishi Y. Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound. Pharmaceutics. 2023 Jun 6;15(6):1665. doi: 10.3390/pharmaceutics15061665.

Jak2 and Jaw Muscles Are Required for Buccopharyngeal Membrane Perforation during Mouth Development

Authors:
Dickinson AJG
Citation:
J Dev Biol. 2023 May 31;11(2):24. doi: 10.3390/jdb11020024
Epub:
Not Epub
Abstract:
The mouth is a central feature of our face, without which we could not eat, breathe, or communicate. A critical and early event...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Dickinson AJG. Jak2 and Jaw Muscles Are Required for Buccopharyngeal Membrane Perforation during Mouth Development. J Dev Biol. 2023 May 31;11(2):24. doi: 10.3390/jdb11020024.

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