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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation

Authors:
Chen X, Li Y, Xu J, Cui Y, Wu Q, Yin H, Li Y, Gao C, Jiang L, Wang H, Wen Z, Yao Z, Wu Z
Citation:
Elife. 2024 Jun 3;12:RP87434. doi: 10.7554/eLife.87434. PMID: 38829202.
Epub:
Not Epub
Abstract:
Styxl2, a poorly characterized pseudophosphatase, was identified as a transcriptional target of the Jak1-Stat1 pathway during...
Link:
https://elifesciences.org/articles/87434
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Li Y, Xu J, Cui Y, Wu Q, Yin H, Li Y, Gao C, Jiang L, Wang H, Wen Z, Yao Z, Wu Z. Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation. Elife. 2024 Jun 3;12:RP87434. doi: 10.7554/eLife.87434. PMID: 38829202..

UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis

Authors:
Kim J, Kim BY, Lee JS, Jeong YM, Cho HJ, Park E, Kim D, Kim SS, Kim BT, Choi YJ, Won YY, Jin HS, Chung YS, Jeong SY
Citation:
Nat Commun. 2023 Jun 20;14(1):3668. doi: 10.1038/s41467-023-39448-8
Epub:
Not Epub
Abstract:
Osteoporosis is a condition characterized by decreased bone mineral density (BMD) and reduced bone strength, leading to an...
Link:
https://www.nature.com/articles/s41467-023-39448-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim J, Kim BY, Lee JS, Jeong YM, Cho HJ, Park E, Kim D, Kim SS, Kim BT, Choi YJ, Won YY, Jin HS, Chung YS, Jeong SY. UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis. Nat Commun. 2023 Jun 20;14(1):3668. doi: 10.1038/s41467-023-39448-8.

Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport

Authors:
Roca FJ, Whitworth LJ, Prag HA, Murphy MP, Ramakrishnan L
Citation:
Science. 2022 Jun 24;376(6600):eabh2841. doi: 10.1126/science.abh2841. Epub 2022 Jun 24
Epub:
Not Epub
Abstract:
Tumor necrosis factor (TNF) is a critical host resistance factor against tuberculosis. However, excess TNF produces...
Link:
https://www.science.org/doi/10.1126/science.abh2841
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roca FJ, Whitworth LJ, Prag HA, Murphy MP, Ramakrishnan L. Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport. Science. 2022 Jun 24;376(6600):eabh2841. doi: 10.1126/science.abh2841. Epub 2022 Jun 24.

Transmembrane protein 150b attenuates BMP signaling in the Xenopus organizer

Authors:
Keum BR, Yeo I, Koo Y, Han W, Choi SC, Kim GH, Han JK
Citation:
J Cell Physiol. 2023 Jul 12. doi: 10.1002/jcp.31059. Online ahead of print
Epub:
Yes
Abstract:
The vertebrate organizer is a specified embryonic tissue that regulates dorsoventral patterning and axis formation. Although...
Link:
https://onlinelibrary.wiley.com/doi/10.1002/jcp.31059
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Keum BR, Yeo I, Koo Y, Han W, Choi SC, Kim GH, Han JK. Transmembrane protein 150b attenuates BMP signaling in the Xenopus organizer. J Cell Physiol. 2023 Jul 12. doi: 10.1002/jcp.31059. Online ahead of print.

The Crucial Role of CTCF in Mitotic Progression during Early Development of Sea Urchin

Authors:
Watanabe K, Fujita M, Okamoto K, Yoshioka H, Moriwaki M, Tagashira H, Awazu A, Yamamoto T, Sakamoto N
Citation:
Dev Growth Differ. 2023 Jul 8. doi: 10.1111/dgd.12875. Online ahead of print
Epub:
Yes
Abstract:
CCCTC-binding factor (CTCF), an insulator protein with 11 zinc fingers, is enriched at the boundaries of topologically...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/dgd.12875
Organism or Cell Type:
Hemicentrotus pulcherrimus (urchin)
Citation Extract:
Watanabe K, Fujita M, Okamoto K, Yoshioka H, Moriwaki M, Tagashira H, Awazu A, Yamamoto T, Sakamoto N. The Crucial Role of CTCF in Mitotic Progression during Early Development of Sea Urchin. Dev Growth Differ. 2023 Jul 8. doi: 10.1111/dgd.12875. Online ahead of print.

Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice

Authors:
Hu M, Bodnar B, Zhang Y, Xie F, Li F, Li S, Zhao J, Zhao R, Gedupoori N, Mo Y, Lin L, Li X, Meng W, Yang X, Wang H, Barbe MF, Srinivasan S, Bethea JR, Mo X, Xu H, Hu W
Citation:
Int J Biol Sci. 2023 Jun 19;19(10):3226-3248. doi: 10.7150/ijbs.78489. eCollection 2023
Epub:
Not Epub
Abstract:
Loss of function in transport protein particles (TRAPP) links a new set of emerging genetic disorders called "...
Link:
https://www.ijbs.com/v19p3226.htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu M, Bodnar B, Zhang Y, Xie F, Li F, Li S, Zhao J, Zhao R, Gedupoori N, Mo Y, Lin L, Li X, Meng W, Yang X, Wang H, Barbe MF, Srinivasan S, Bethea JR, Mo X, Xu H, Hu W. Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice. Int J Biol Sci. 2023 Jun 19;19(10):3226-3248. doi: 10.7150/ijbs.78489. eCollection 2023.

Cell competition for neuron-derived trophic factor controls the turnover and lifespan of microglia

Authors:
Yu T, Kuang H, Wu X, Huang Y, Wang J, Wen Z
Citation:
Sci Adv. 2023 Jun 16;9(24):eadf9790. doi: 10.1126/sciadv.adf9790. Epub 2023 Jun 16
Epub:
Not Epub
Abstract:
Microglia are brain-resident macrophages capable of long-term maintenance through self-renewal. Yet the mechanism governing the...
Link:
https://www.science.org/doi/10.1126/sciadv.adf9790
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu T, Kuang H, Wu X, Huang Y, Wang J, Wen Z. Cell competition for neuron-derived trophic factor controls the turnover and lifespan of microglia. Sci Adv. 2023 Jun 16;9(24):eadf9790. doi: 10.1126/sciadv.adf9790. Epub 2023 Jun 16.

ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer

Authors:
Pandey A, Cousin H, Horr B, Alfandari D
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.06.13.544797
Epub:
Not Epub
Abstract:
Cranial neural crest (CNC) cells are induced at the border of the neural plate by a combination of FGF, Wnt, and BMP4 signaling...
Link:
https://www.biorxiv.org/content/10.1101/2023.06.13.544797v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pandey A, Cousin H, Horr B, Alfandari D. ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer. bioRxiv. 2023;[preprint] doi:10.1101/2023.06.13.544797.

Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis

Authors:
Lv P, Liu F
Citation:
Development. 2023 Oct 15;150(20):dev201690. doi: 10.1242/dev.201690. Epub 2023 Jun 15
Epub:
Not Epub
Abstract:
The crosstalk between hematopoietic lineages is important for developmental hematopoiesis. However, the role of primitive red...
Link:
https://journals.biologists.com/dev/article/150/20/dev201690/316750/Heme-deficient-primitive-red-blood-cells-induce
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lv P, Liu F. Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis. Development. 2023 Oct 15;150(20):dev201690. doi: 10.1242/dev.201690. Epub 2023 Jun 15.

Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1

Authors:
Hipke K, Pitter B, Hruscha A, van Bebber F, Modic M, Bansal V, Lewandowski SA, Orozco D, Edbauer D, Bonn S, Haass C, Pohl U, Montanez E, Schmid B
Citation:
Front Cell Dev Biol. 2023 Jun 13;11:1169962. doi: 10.3389/fcell.2023.1169962. eCollection 2023
Epub:
Not Epub
Abstract:
Aggregation of the Tar DNA-binding protein of 43 kDa (TDP-43) is a pathological hallmark of amyotrophic lateral sclerosis and...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2023.1169962/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hipke K, Pitter B, Hruscha A, van Bebber F, Modic M, Bansal V, Lewandowski SA, Orozco D, Edbauer D, Bonn S, Haass C, Pohl U, Montanez E, Schmid B. Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1. Front Cell Dev Biol. 2023 Jun 13;11:1169962. doi: 10.3389/fcell.2023.1169962. eCollection 2023.

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