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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis.

Authors:
Serres MP, Shaughnessy R, Escot S, Hammich H, Cuvelier F, Salles A, Rocancourt M, Verdon Q, Gaffuri A-L, Sourigues Y, Malherbe G, Velikovsky L, Chardon F, Sassoon N, Tinevez J-Y, Callebaut I, Formstecher E, Houdusse A, David NB, Pylypenko O, Echard A
Citation:
Dev Cell. 2023;[Epub ahead of print] doi:10.1016/j.devcel.2023.09.010
Epub:
Not Epub
Abstract:
Cilia protrude from the cell surface and play critical roles in intracellular signaling, environmental sensing, and development...
Link:
https://www.cell.com/developmental-cell/pdf/S1534-5807(23)00512-9.pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serres MP, Shaughnessy R, Escot S, Hammich H, Cuvelier F, Salles A, Rocancourt M, Verdon Q, Gaffuri A-L, Sourigues Y, Malherbe G, Velikovsky L, Chardon F, Sassoon N, Tinevez J-Y, Callebaut I, Formstecher E, Houdusse A, David NB, Pylypenko O, Echard A. MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis.. Dev Cell. 2023;[Epub ahead of print] doi:10.1016/j.devcel.2023.09.010.

Direct TGF-ß signaling via alk4/5/7 pathway is involved in gut bending in sea urchin embryos

Authors:
Suzuki H, Yaguchi S
Citation:
Dev Dyn. 2022 Jan;251(1):226-234. doi: 10.1002/dvdy.442. Epub 2021 Nov 27
Epub:
Not Epub
Abstract:
Background: Precise gastrulation is essential for formation of functional bodies in cnidarians and bilaterians. Previously, by...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.442
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Suzuki H, Yaguchi S. Direct TGF-ß signaling via alk4/5/7 pathway is involved in gut bending in sea urchin embryos. Dev Dyn. 2022 Jan;251(1):226-234. doi: 10.1002/dvdy.442. Epub 2021 Nov 27.

The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling

Authors:
Li Y, Li C, Liu M, Liu S, Liu F, Wang L
Citation:
Development. 2023 Nov 1;150(21):dev201890. doi: 10.1242/dev.201890. Epub 2023 Oct 24
Epub:
Not Epub
Abstract:
In vertebrates, the earliest hematopoietic stem and progenitor cells (HSPCs) are derived from a subset of specialized...
Link:
https://journals.biologists.com/dev/article/150/21/dev201890/334149/The-RNA-binding-protein-CSDE1-promotes
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Li C, Liu M, Liu S, Liu F, Wang L. The RNA-binding protein CSDE1 promotes hematopoietic stem and progenitor cell generation via translational control of Wnt signaling. Development. 2023 Nov 1;150(21):dev201890. doi: 10.1242/dev.201890. Epub 2023 Oct 24.

Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry

Authors:
Karasawa K, Duchoslav E, Burton L, Kawakami J, Baba T
Citation:
Anal Chem. 2023 Oct 23. doi: 10.1021/acs.analchem.3c03621. Online ahead of print
Epub:
Yes
Abstract:
We report the first sequencing of morpholino antisense oligonucleotides (phosphorodiamidate morpholino oligomers, PMOs) using...
Link:
https://pubs.acs.org/doi/10.1021/acs.analchem.3c03621
Citation Extract:
Karasawa K, Duchoslav E, Burton L, Kawakami J, Baba T. Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry. Anal Chem. 2023 Oct 23. doi: 10.1021/acs.analchem.3c03621. Online ahead of print.

Specific CaMKIIs mediate convergent extension cell movements in early zebrafish development

Authors:
McLeod JJ, Rothschild SC, Francescatto L, Kim H, Tombes RM
Citation:
Dev Dyn. 2023 Oct 20. doi: 10.1002/dvdy.665. Online ahead of print
Epub:
Yes
Abstract:
Background: Noncanonical Wnts are morphogens that can elevate intracellular Ca2+ , activate the Ca2+ /calmodulin-dependent...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.665
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McLeod JJ, Rothschild SC, Francescatto L, Kim H, Tombes RM. Specific CaMKIIs mediate convergent extension cell movements in early zebrafish development. Dev Dyn. 2023 Oct 20. doi: 10.1002/dvdy.665. Online ahead of print.

Zmym4 is required for early cranial gene expression and craniofacial cartilage formation

Authors:
Jourdeuil K, Neilson KM, Cousin H, Tavares ALP, Majumdar HD, Alfandari D, Moody SA
Citation:
Front Cell Dev Biol. 2023 Oct 3;11:1274788. doi: 10.3389/fcell.2023.1274788. eCollection 2023
Epub:
Not Epub
Abstract:
Introduction: The Six1 transcription factor plays important roles in the development of cranial sensory organs, and point...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2023.1274788/full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Jourdeuil K, Neilson KM, Cousin H, Tavares ALP, Majumdar HD, Alfandari D, Moody SA. Zmym4 is required for early cranial gene expression and craniofacial cartilage formation. Front Cell Dev Biol. 2023 Oct 3;11:1274788. doi: 10.3389/fcell.2023.1274788. eCollection 2023.

Two novel CHN1 variants identified in Duane retraction syndrome pedigrees disrupt development of ocular motor nerves in zebrafish

Authors:
Zhang R, Jia H, Chang Q, Zhang Z, Peng C, Ma Q, Liang Y, Yang S, Jiao Y
Citation:
J Hum Genet. 2023;[Epub ahead of print] doi:10.1038/s10038-023-01201-w
Epub:
Yes
Abstract:
Duane retraction syndrome (DRS) is a rare congenital eye movement disorder causing by the dysplasia of abducens nerve, and has...
Link:
https://www.nature.com/articles/s10038-023-01201-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang R, Jia H, Chang Q, Zhang Z, Peng C, Ma Q, Liang Y, Yang S, Jiao Y. Two novel CHN1 variants identified in Duane retraction syndrome pedigrees disrupt development of ocular motor nerves in zebrafish. J Hum Genet. 2023;[Epub ahead of print] doi:10.1038/s10038-023-01201-w.

Ciliary localization of a light-activated neuronal GPCR shapes behavior

Authors:
Winans AM, Friedmann D, Stanley C, Xiao T, Liu TL, Chang CJ, Isacoff EY
Citation:
Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2311131120. doi: 10.1073/pnas.2311131120. Epub 2023 Oct 16
Epub:
Not Epub
Abstract:
Many neurons in the central nervous system produce a single primary cilium that serves as a specialized signaling organelle....
Link:
https://www.pnas.org/doi/10.1073/pnas.2311131120
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Winans AM, Friedmann D, Stanley C, Xiao T, Liu TL, Chang CJ, Isacoff EY. Ciliary localization of a light-activated neuronal GPCR shapes behavior. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2311131120. doi: 10.1073/pnas.2311131120. Epub 2023 Oct 16.

A novel role for the chloride intracellular channel protein Clic5 in ciliary function

Authors:
Ott E, Hoff S, Indorf L, Ditengou FA, Müller J, Renschler G, Lienkamp SS, Kramer-Zucker A, Bergmann C, Epting D
Citation:
Sci Rep. 2023 Oct 17;13(1):17647. doi: 10.1038/s41598-023-44235-y
Epub:
Not Epub
Abstract:
CLIC5 belongs to a family of ion channels with six members reported so far. In vertebrates, the CLIC5 gene encodes two...
Link:
https://www.nature.com/articles/s41598-023-44235-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ott E, Hoff S, Indorf L, Ditengou FA, Müller J, Renschler G, Lienkamp SS, Kramer-Zucker A, Bergmann C, Epting D. A novel role for the chloride intracellular channel protein Clic5 in ciliary function. Sci Rep. 2023 Oct 17;13(1):17647. doi: 10.1038/s41598-023-44235-y.

Xbra modulates the activity of linker region phosporlated Smad1 during Xenopus somitogenesis

Authors:
Kim J, Kumar S, Umair Z, Goutam RS, Lee U
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.10.11.561863
Epub:
Not Epub
Abstract:
The Bmp/Smad1 pathway plays a crucial role in developmental processes and tissue homeostasis. Mitogen-activated protein kinase...
Link:
https://www.biorxiv.org/content/10.1101/2023.10.11.561863v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kim J, Kumar S, Umair Z, Goutam RS, Lee U. Xbra modulates the activity of linker region phosporlated Smad1 during Xenopus somitogenesis. bioRxiv. 2023;[preprint] doi:10.1101/2023.10.11.561863.

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