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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
FARS2 Deficiency Causes Cardiomyopathy by Disrupting Mitochondrial Homeostasis and the Mitochondrial Quality Control System. Circulation
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Citation:
2024 Apr 16;149(16):1268-1284. doi: 10.1161/CIRCULATIONAHA.123.064489. Epub 2024 Feb 16. PMID: 38362779; PMCID: PMC11017836 Epub:
Yes Abstract:
Background: Hypertrophic cardiomyopathy (HCM) is a common heritable heart disease. Although HCM has been reported to be... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li B, Liu F, Chen X, Chen T, Zhang J, Liu Y, Yao Y, Hu W, Zhang M, Wang B, Liu L, Chen K, Wu Y. FARS2 Deficiency Causes Cardiomyopathy by Disrupting Mitochondrial Homeostasis and the Mitochondrial Quality Control System. Circulation. 2024 Apr 16;149(16):1268-1284. doi: 10.1161/CIRCULATIONAHA.123.064489. Epub 2024 Feb 16. PMID: 38362779; PMCID: PMC11017836. |
Clinical, immunohistochemical, and genetic characterization of splice-altering biallelic DES variants: Therapeutic implications
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Citation:
HGG Adv. 2024 Feb 2;5(2):100274. doi: 10.1016/j.xhgg.2024.100274. Online ahead of print Epub:
Not Epub Abstract:
Pathogenic variants in the DES gene clinically manifest as progressive skeletal muscle weakness, cardiomyopathy with associated... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: P1 Citation Extract: Geist Hauserman J, Laverty CG, Donkervoort S, Hu Y, Silverstein S, Neuhaus SB, Saade D, Vaughn G, Malicki D, Kaur R, Li Y, Luo Y, Liu P, Burr P, Foley AR, Mohassel P, Bönnemann CG. Clinical, immunohistochemical, and genetic characterization of splice-altering biallelic DES variants: Therapeutic implications. HGG Adv. 2024 Feb 2;5(2):100274. doi: 10.1016/j.xhgg.2024.100274. Online ahead of print. |
Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia
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Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.02.14.580281 Epub:
Not Epub Abstract:
Vertebrate motile cilia are broadly classified as (9+2) or (9+0), based on the presence or absence of the central pair... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roy S, Lu H, Twan WK, Ikawa Y, Khare VP, Mukherjee I, Chua KX, Chakrabarti S, Hamada H. Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia. bioRxiv. 2024;[preprint] doi:10.1101/2024.02.14.580281. |
Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior
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Citation:
Nucleic Acids Res. 2024;[Epub]:gkae093. doi:10.1093/nar/gkae093 Epub:
Not Epub Abstract:
Complex biological processes are regulated by both genetic and epigenetic programs. One class of epigenetic modifications is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Guo J, Zou Z, Dou X, Zhao X, Wang Y, Wei L, Pi Y, Wang Y, He C, Guo S. Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior. Nucleic Acids Res. 2024;[Epub]:gkae093. doi:10.1093/nar/gkae093. |
Apela promotes blood vessel regeneration and remodeling in zebrafish
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Citation:
Sci Rep. 2024 Feb 14;14(1):3718. doi: 10.1038/s41598-023-50677-1 Epub:
Not Epub Abstract:
In contrast to adult mammals, zebrafish display a high capacity to heal injuries and repair damage to various organs. One of... Delivery Method:
microinjection, injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Nys N, Khatib AM, Siegfried G. Apela promotes blood vessel regeneration and remodeling in zebrafish. Sci Rep. 2024 Feb 14;14(1):3718. doi: 10.1038/s41598-023-50677-1. |
Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm
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Citation:
PLoS One. 2024 Feb 12;19(2):e0297420. doi: 10.1371/journal.pone.0297420. eCollection 2024 Epub:
Not Epub Abstract:
Convergent extension of the chordamesoderm is the best-examined gastrulation movement in Xenopus. Here we study general... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Luu O, Barua D, Winklbauer R. Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm. PLoS One. 2024 Feb 12;19(2):e0297420. doi: 10.1371/journal.pone.0297420. eCollection 2024. |
Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos
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Citation:
J Physiol. 2024 Feb 12. doi: 10.1113/JP285490. Online ahead of print Epub:
Yes Abstract:
Cardiac trabeculae are uneven ventricular muscular structures that develop during early embryonic heart development at the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cairelli AG, Gendernalik A, Chan WX, Nguyen P, Vermot J, Lee J, Bark D Jr, Yap CH. Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos. J Physiol. 2024 Feb 12. doi: 10.1113/JP285490. Online ahead of print. |
An alternative strategy to increasing influenza virus replication for vaccine production in chicken embryo fibroblast (DF-1) cells by inhibiting interferon alpha and beta using peptide-conjugated phosphorodiamidate morpholino oligomers
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Citation:
J Med Microbiol. 2024 Feb;73(2). doi: 10.1099/jmm.0.001807 Epub:
Not Epub Abstract:
Introduction. Influenza is a global health issue causing substantial health and economic burdens on affected populations.... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: DF-1 chick embryo fibroblasts Citation Extract: Prescott MA, Moulton H, Pastey MK. An alternative strategy to increasing influenza virus replication for vaccine production in chicken embryo fibroblast (DF-1) cells by inhibiting interferon alpha and beta using peptide-conjugated phosphorodiamidate morpholino oligomers. J Med Microbiol. 2024 Feb;73(2). doi: 10.1099/jmm.0.001807. |
Comprehensive analysis of diel rhythmic expression of the medaka toll-like receptor gene family
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Citation:
Dev Comp Immunol. 2024;[Epub] doi:10.1016/j.dci.2024.105143 Epub:
Not Epub Abstract:
Several immune-related genes, including Toll-like receptors (TLR), are associated with circadian rhythms in mammals. However,... Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Hata T, Shimawaki H, Setoguchi S, Morimoto N, Hikima J-i, Sakai M, Kono T. Comprehensive analysis of diel rhythmic expression of the medaka toll-like receptor gene family. Dev Comp Immunol. 2024;[Epub] doi:10.1016/j.dci.2024.105143. |
Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance
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Citation:
Int J Mol Sci. 2024;25(4):2079; doi:10.3390/ijms25042079 Epub:
Not Epub Abstract:
The hypoxic pattern of glioblastoma (GBM) is known to be a primary cause of radioresistance. Our study explored the possibility... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: U87 human glioblastoma Citation Extract: Pucci G, Minafra L, Bravatà V, Calvaruso M, Turturici G, Cammarata FP, Savoca G, Abbate B, Russo G, Cavalieri V, Forte GI. Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance. Int J Mol Sci. 2024;25(4):2079; doi:10.3390/ijms25042079. |