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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Sulindac selectively induces autophagic apoptosis of GABAergic neurons and alters motor behaviour in zebrafish

Authors:
Sun W, Wang M, Zhao J, Zhao S, Zhu W, Wu X, Li F, Liu W, Wang Z, Gao M, Zhang Y, Xu J, Zhang M, Wang Q, Wen Z, Shen J, Zhang W, Huang Z
Citation:
Nat Commun. 2023 Sep 2;14(1):5351. doi: 10.1038/s41467-023-41114-y
Epub:
Not Epub
Abstract:
Nonsteroidal anti-inflammatory drugs compose one of the most widely used classes of medications, but the risks for early...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun W, Wang M, Zhao J, Zhao S, Zhu W, Wu X, Li F, Liu W, Wang Z, Gao M, Zhang Y, Xu J, Zhang M, Wang Q, Wen Z, Shen J, Zhang W, Huang Z. Sulindac selectively induces autophagic apoptosis of GABAergic neurons and alters motor behaviour in zebrafish. Nat Commun. 2023 Sep 2;14(1):5351. doi: 10.1038/s41467-023-41114-y.

Characterization of Msantd4 Gene in the Development of Xenopus Laevis

Authors:
Hu Z, Liu Y, Guo C, Chen C, Tu Y, Zeng J, Ma F, Yang J
Citation:
SSRN. 2023;[preprint] doi:10.2139/ssrn.4559111
Epub:
Not Epub
Abstract:
msantd4 is a not well-characterized gene had been revealed to function as a repressor of HSPB1 and indirectly involved in the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hu Z, Liu Y, Guo C, Chen C, Tu Y, Zeng J, Ma F, Yang J. Characterization of Msantd4 Gene in the Development of Xenopus Laevis. SSRN. 2023;[preprint] doi:10.2139/ssrn.4559111 .

Disruption of fos causes craniofacial anomalies in developing zebrafish

Authors:
Maili L, Tandon B, Yuan Q, Menezes S, Chiu F, Hashmi SS, Letra A, Eisenhoffer GT, Hecht JT
Citation:
Front Cell Dev Biol. 2023 Aug 16;11:1141893. doi: 10.3389/fcell.2023.1141893. eCollection 2023
Epub:
Not Epub
Abstract:
Craniofacial development is a complex and tightly regulated process and disruptions can lead to structural birth defects, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maili L, Tandon B, Yuan Q, Menezes S, Chiu F, Hashmi SS, Letra A, Eisenhoffer GT, Hecht JT. Disruption of fos causes craniofacial anomalies in developing zebrafish. Front Cell Dev Biol. 2023 Aug 16;11:1141893. doi: 10.3389/fcell.2023.1141893. eCollection 2023.

DMD antisense oligonucleotide mediated exon skipping efficiency correlates with flanking intron retention time and target position within the exon

Authors:
Goossens R, Verwey N, Ariyurek Y, Schnell F, Aartsma-Rus A
Citation:
RNA Biol. 2023 Jan;20(1):693-702. doi: 10.1080/15476286.2023.2254041
Epub:
Not Epub
Abstract:
Mutations in the DMD gene are causative for Duchenne muscular dystrophy (DMD). Antisense oligonucleotide (AON) mediated exon...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: healthy control (KM155) and DMD patient cells (8036 and 6311) differentiated to myotubes
Citation Extract:
Goossens R, Verwey N, Ariyurek Y, Schnell F, Aartsma-Rus A. DMD antisense oligonucleotide mediated exon skipping efficiency correlates with flanking intron retention time and target position within the exon. RNA Biol. 2023 Jan;20(1):693-702. doi: 10.1080/15476286.2023.2254041.

Apical size and deltaA expression predict adult neural stem cell decisions along lineage progression

Authors:
Mancini L, Guirao B, Ortica S, Labusch M, Cheysson F, Bonnet V, Phan MS, Herbert S, Mahou P, Menant E, Bedu S, Tinevez J-Y, Baroud C, Beaurepaire E, Bellaiche Y, Bally-Cuif L, Nicolas Dray N
Citation:
Sci Adv. 2023;9,eadg7519 doi:10.1126/sciadv.adg7519
Epub:
Not Epub
Abstract:
The maintenance of neural stem cells (NSCs) in the adult brain depends on their activation frequency and division mode. Using...
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Mancini L, Guirao B, Ortica S, Labusch M, Cheysson F, Bonnet V, Phan MS, Herbert S, Mahou P, Menant E, Bedu S, Tinevez J-Y, Baroud C, Beaurepaire E, Bellaiche Y, Bally-Cuif L, Nicolas Dray N. Apical size and deltaA expression predict adult neural stem cell decisions along lineage progression. Sci Adv. 2023;9,eadg7519 doi:10.1126/sciadv.adg7519.

Downregulation of Zebrafish Cytosolic Sialidase Neu3.2 Affects Skeletal Muscle Development

Authors:
Zizioli D, Codenotti S, Benaglia G, Manzoni M, Massardi E, Fanzani A, Borsani G, Monti E
Citation:
Int J Mol Sci. 2023;24(17):13578. doi:10.3390/ijms241713578
Epub:
Not Epub
Abstract:
Sialidases remove terminal sialic acids residues from the non-reducing ends of glycoconjugates. They have been recognized as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zizioli D, Codenotti S, Benaglia G, Manzoni M, Massardi E, Fanzani A, Borsani G, Monti E. Downregulation of Zebrafish Cytosolic Sialidase Neu3.2 Affects Skeletal Muscle Development. Int J Mol Sci. 2023;24(17):13578. doi:10.3390/ijms241713578 .

YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths

Authors:
Lin J, Zhan G, Liu J, Maimaitiyiming Y, Deng Z, Li B, Su K, Chen J, Sun S, Zheng W, Yu X, He F, Cheng X, Wang L, Shen B, Yao Z, Yang X, Zhang J, He W, Wu H, Naranmandura H, Chang K-J, Min J, Ma J, Björklund M, Xu P-F, Wang F, Hsu C-H
Citation:
Natl Sci Rev. 2023;nwad227. doi:10.1093/nsr/nwad227
Epub:
Not Epub
Abstract:
N6-methyladenosine (m6A) is a critical regulator of RNA fate [1,2], but whether and how m6A executes its functions in different...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin J, Zhan G, Liu J, Maimaitiyiming Y, Deng Z, Li B, Su K, Chen J, Sun S, Zheng W, Yu X, He F, Cheng X, Wang L, Shen B, Yao Z, Yang X, Zhang J, He W, Wu H, Naranmandura H, Chang K-J, Min J, Ma J, Björklund M, Xu P-F, Wang F, Hsu C-H. YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths. Natl Sci Rev. 2023;nwad227. doi:10.1093/nsr/nwad227.

Zbtb16 mediates a switch between Fgf signalling regimes in the developing hindbrain

Authors:
Leino SA, Constable SCJ, Streit A, Wilkinson DG
Citation:
Development. 2023 Aug 28:dev.201319. doi: 10.1242/dev.201319. Online ahead of print
Epub:
Yes
Abstract:
Developing tissues are sequentially patterned by extracellular signals that are turned on and off at specific times. In the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Leino SA, Constable SCJ, Streit A, Wilkinson DG. Zbtb16 mediates a switch between Fgf signalling regimes in the developing hindbrain. Development. 2023 Aug 28:dev.201319. doi: 10.1242/dev.201319. Online ahead of print.

Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation

Authors:
Pan H-C, Lo K-C, Wang Y-H, Huang H-T, Cheng S-C, Sun C-Y, Chen Y-H
Citation:
Fishes. 2023;8(9):440.doi:10.3390/fishes8090440
Epub:
Not Epub
Abstract:
(1) Background: Klotho is a multifunctional protein, but its biophysiological roles during fish early development are unclear...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pan H-C, Lo K-C, Wang Y-H, Huang H-T, Cheng S-C, Sun C-Y, Chen Y-H. Knockdown of klotho Leads to Cell Movement Impairment during Zebrafish Gastrulation. Fishes. 2023;8(9):440.doi:10.3390/fishes8090440.

DRAM1 confers resistance to Salmonella infection

Authors:
Masud S, Xie J, Grijmans BJM, van der Kooij S, Zhang R, Prajsnar TK, Meijer AH
Citation:
Autophagy Rep. 2023;2(1):2242715. doi:10.1080/27694127.2023.2242715
Epub:
Not Epub
Abstract:
DRAM1 is an infection inducible autophagy modulator, previously shown to promote autophagic and lysosomal defense responses...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Masud S, Xie J, Grijmans BJM, van der Kooij S, Zhang R, Prajsnar TK, Meijer AH. DRAM1 confers resistance to Salmonella infection. Autophagy Rep. 2023;2(1):2242715. doi:10.1080/27694127.2023.2242715.

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