You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12236 scientific papers returned from the database with the search filters currently being used below.

CLN3 deficiency leads to neurological and metabolic perturbations during early development

Authors:
Heins-Marroquin U, Singh RR, Perathoner S, Gavotto F, Merino Ruiz C, Patraskaki M, Gomez-Giro G, Kleine Borgmann F, Meyer M, Carpentier A, Warmoes MO, Jäger C, Mittelbronn M, Schwamborn JC, Cordero-Maldonado ML, Crawford AD, Schymanski EL, Linster CL
Citation:
Life Sci Alliance. 2024 Jan 9;7(3):e202302057 doi: 10.26508/lsa.202302057. Print 2024 Mar
Epub:
Not Epub
Abstract:
Juvenile neuronal ceroid lipofuscinosis (or Batten disease) is an autosomal recessive, rare neurodegenerative disorder that...
Link:
https://www.life-science-alliance.org/content/7/3/e202302057
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Heins-Marroquin U, Singh RR, Perathoner S, Gavotto F, Merino Ruiz C, Patraskaki M, Gomez-Giro G, Kleine Borgmann F, Meyer M, Carpentier A, Warmoes MO, Jäger C, Mittelbronn M, Schwamborn JC, Cordero-Maldonado ML, Crawford AD, Schymanski EL, Linster CL. CLN3 deficiency leads to neurological and metabolic perturbations during early development . Life Sci Alliance. 2024 Jan 9;7(3):e202302057 doi: 10.26508/lsa.202302057. Print 2024 Mar.

Identification of End-Binding 1 Protein as Novel α-4 Giardin-Binding Partners in Giardia lamblia Trophozoites

Authors:
Zhang K, Shen H, Wang Y, Shen H, Zhang C, Zou X, Yu Y, Tian X, Wang Y
Citation:
Acta Parasitol. 2024 Jan 11. doi: 10.1007/s11686-023-00774-y. Online ahead of print
Epub:
Yes
Abstract:
Background: Giardia lamblia (syn. G. intestinalis, G. duodenalis) is a primitive opportunistic protozoon, and one of the...
Link:
https://link.springer.com/article/10.1007/s11686-023-00774-y
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Zhang K, Shen H, Wang Y, Shen H, Zhang C, Zou X, Yu Y, Tian X, Wang Y. Identification of End-Binding 1 Protein as Novel α-4 Giardin-Binding Partners in Giardia lamblia Trophozoites. Acta Parasitol. 2024 Jan 11. doi: 10.1007/s11686-023-00774-y. Online ahead of print.

Iprodione induces hepatotoxicity in zebrafish by mediating ROS generation and upregulating p53 signalling pathway

Authors:
Hu W, Chen G, Yuan W, Guo C, Liu F, Zhang S, Cao Z
Citation:
Ecotoxicol Environ Saf. 2024 Jan 4;270:115911. doi: 10.1016/j.ecoenv.2023.115911. Online ahead of print
Epub:
Not Epub
Abstract:
Iprodione is an effective and broad-spectrum fungicide commonly used for early disease control in fruit trees and vegetables....
Link:
https://www.sciencedirect.com/science/article/pii/S014765132301415X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu W, Chen G, Yuan W, Guo C, Liu F, Zhang S, Cao Z. Iprodione induces hepatotoxicity in zebrafish by mediating ROS generation and upregulating p53 signalling pathway. Ecotoxicol Environ Saf. 2024 Jan 4;270:115911. doi: 10.1016/j.ecoenv.2023.115911. Online ahead of print.

Damage-induced basal epithelial cell migration modulates the spatial organization of redox signaling and sensory neuron regeneration

Authors:
Fister AM, Horn A, Lasarev M, Huttenlocher A
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.14.532628
Epub:
Not Epub
Abstract:
Epithelial damage leads to early reactive oxygen species (ROS) signaling, which regulates sensory neuron regeneration and...
Link:
https://www.biorxiv.org/content/10.1101/2023.03.14.532628v2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fister AM, Horn A, Lasarev M, Huttenlocher A. Damage-induced basal epithelial cell migration modulates the spatial organization of redox signaling and sensory neuron regeneration. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.14.532628 .

Antagonistic regulation of homeologous uncx.L and uncx.S genes orchestrates myotome and sclerotome differentiation in the evolutionarily divergent vertebral column of Xenopus laevis

Authors:
Sánchez RS, Lazarte MA, Abdala VSL, Sánchez SS
Citation:
J Exp Zool B Mol Dev Evol. 2024 Jun;342(4):350-367. doi: 10.1002/jez.b.23235. Epub 2023 Dec 28. PMID: 38155515.
Epub:
Yes
Abstract:
In anurans, the vertebral column diverges widely from that of other tetrapods; yet the molecular mechanisms underlying its...
Link:
https://onlinelibrary.wiley.com/doi/10.1002/jez.b.23235
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sánchez RS, Lazarte MA, Abdala VSL, Sánchez SS. Antagonistic regulation of homeologous uncx.L and uncx.S genes orchestrates myotome and sclerotome differentiation in the evolutionarily divergent vertebral column of Xenopus laevis. J Exp Zool B Mol Dev Evol. 2024 Jun;342(4):350-367. doi: 10.1002/jez.b.23235. Epub 2023 Dec 28. PMID: 38155515..

An in vivo drug screen in zebrafish reveals that cyclooxygenase 2-derived prostaglandin D2 promotes spinal cord neurogenesis

Authors:
González-Llera L, Sobrido-Cameán D, Quelle-Regaldie A, Sánchez L, Barreiro-Iglesias A
Citation:
Cell Prolif. 2023 Dec 28:e13594. doi: 10.1111/cpr.13594. Online ahead of print
Epub:
Not Epub
Abstract:
The study of neurogenesis is essential to understanding fundamental developmental processes and for the development of cell...
Link:
https://onlinelibrary.wiley.com/doi/10.1111/cpr.13594
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
González-Llera L, Sobrido-Cameán D, Quelle-Regaldie A, Sánchez L, Barreiro-Iglesias A. An in vivo drug screen in zebrafish reveals that cyclooxygenase 2-derived prostaglandin D2 promotes spinal cord neurogenesis. Cell Prolif. 2023 Dec 28:e13594. doi: 10.1111/cpr.13594. Online ahead of print.

Cytoglobin regulates NO-dependent cilia motility and organ laterality during development

Authors:
Rochon ER, Xue J, Mohammed MS, Smith C, Hay-Schmidt A, DeMartino AW, Clark A, Xu Q, Lo CW, Tsang M, Tejero J, Gladwin MT, Corti P
Citation:
Nat Commun. 2023 Dec 14;14(1):8333. doi: 10.1038/s41467-023-43544-0
Epub:
Not Epub
Abstract:
Cytoglobin is a heme protein with unresolved physiological function. Genetic deletion of zebrafish cytoglobin (cygb2) causes...
Link:
https://www.nature.com/articles/s41467-023-43544-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rochon ER, Xue J, Mohammed MS, Smith C, Hay-Schmidt A, DeMartino AW, Clark A, Xu Q, Lo CW, Tsang M, Tejero J, Gladwin MT, Corti P. Cytoglobin regulates NO-dependent cilia motility and organ laterality during development. Nat Commun. 2023 Dec 14;14(1):8333. doi: 10.1038/s41467-023-43544-0.

A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus

Authors:
Singh AK, Allington G, Viviano S, McGee S, Kiziltug E, Ma S, Zhao S, Mekbib KY, Shohfi JP, Duy PQ, DeSpenza T Jr, Furey CG, Reeves BC, Smith H, Sousa AMM, Cherskov A, Allocco A, Nelson-Williams C, Haider S, Rizvi SRA, Alper SL, Sestan N, Shimelis H, Walsh LK, Lifton RP, Moreno-De-Luca A, Jin SC, Kruszka P, Deniz E, Kahle KT
Citation:
Brain. 2023 Dec 21:awad405. doi: 10.1093/brain/awad405. Online ahead of print
Epub:
Yes
Abstract:
Hydrocephalus, characterized by cerebral ventriculomegaly, is the most common disorder requiring brain surgery in children....
Link:
https://academic.oup.com/brain/advance-article-abstract/doi/10.1093/brain/awad405/7490822
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Singh AK, Allington G, Viviano S, McGee S, Kiziltug E, Ma S, Zhao S, Mekbib KY, Shohfi JP, Duy PQ, DeSpenza T Jr, Furey CG, Reeves BC, Smith H, Sousa AMM, Cherskov A, Allocco A, Nelson-Williams C, Haider S, Rizvi SRA, Alper SL, Sestan N, Shimelis H, Walsh LK, Lifton RP, Moreno-De-Luca A, Jin SC, Kruszka P, Deniz E, Kahle KT. A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus. Brain. 2023 Dec 21:awad405. doi: 10.1093/brain/awad405. Online ahead of print.

CRISPR/Cas9-mediated nexilin deficiency interferes with cardiac contractile function in zebrafish in vivo

Authors:
Hofeichner J, Gahr BM, Huber M, Boos A, Rottbauer W, Just S
Citation:
Sci Rep. 2023 Dec 19;13(1):22679. doi: 10.1038/s41598-023-50065-9
Epub:
Not Epub
Abstract:
Nexilin (NEXN) plays a crucial role in stabilizing the sarcomeric Z-disk of striated muscle fibers and, when mutated, leads to...
Link:
https://www.nature.com/articles/s41598-023-50065-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hofeichner J, Gahr BM, Huber M, Boos A, Rottbauer W, Just S. CRISPR/Cas9-mediated nexilin deficiency interferes with cardiac contractile function in zebrafish in vivo. Sci Rep. 2023 Dec 19;13(1):22679. doi: 10.1038/s41598-023-50065-9.

CLEC12A sensitizes differentially responsive breast cancer cells to the anti-cancer effects of artemisinin by repressing autophagy and inflammation

Authors:
Chatterjee R, Shukla A, Chakrabarti K, Chatterji U
Citation:
Front Oncol. 2023 Dec 8;13:1242432. doi: 10.3389/fonc.2023.1242432. eCollection 2023
Epub:
Not Epub
Abstract:
Background: Enhanced inflammatory responses promote tumor progression by activating toll-like receptors (TLRs), which in turn...
Link:
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1242432/full
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse 4T1 xenograft
Citation Extract:
Chatterjee R, Shukla A, Chakrabarti K, Chatterji U. CLEC12A sensitizes differentially responsive breast cancer cells to the anti-cancer effects of artemisinin by repressing autophagy and inflammation. Front Oncol. 2023 Dec 8;13:1242432. doi: 10.3389/fonc.2023.1242432. eCollection 2023.

Pages