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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance
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Citation:
Int J Mol Sci. 2024;25(4):2079; doi:10.3390/ijms25042079 Epub:
Not Epub Abstract:
The hypoxic pattern of glioblastoma (GBM) is known to be a primary cause of radioresistance. Our study explored the possibility... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: U87 human glioblastoma Citation Extract: Pucci G, Minafra L, Bravatà V, Calvaruso M, Turturici G, Cammarata FP, Savoca G, Abbate B, Russo G, Cavalieri V, Forte GI. Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance. Int J Mol Sci. 2024;25(4):2079; doi:10.3390/ijms25042079. |
Znf687 recruits Brd4-Smrt complex to regulate gfi1aa during neutrophil development
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Citation:
Leukemia. 2024;[Epub] doi:10.1038/s41375-024-02165-2 Epub:
Not Epub Abstract:
Neutrophils are key component of the innate immune system in vertebrates. Diverse transcription factors and cofactors act in a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan L, Tan S, Wang H, Yuan H, Liu X, Chen Y, de Thé H, Zhu J, Zhou J. Znf687 recruits Brd4-Smrt complex to regulate gfi1aa during neutrophil development. Leukemia. 2024;[Epub] doi:10.1038/s41375-024-02165-2. |
Analysis of SMAD1/5 target genes in a sea anemone reveals ZSWIM4-6 as a novel BMP signaling modulator
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Citation:
Elife. 2024 Feb 7;13:e80803. doi: 10.7554/eLife.80803 Epub:
Not Epub Abstract:
BMP signaling has a conserved function in patterning the dorsal-ventral body axis in Bilateria and the directive axis in... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Knabl P, Schauer A, Pomreinke AP, Zimmermann B, Rogers KW, Čapek D, Müller P, Genikhovich G. Analysis of SMAD1/5 target genes in a sea anemone reveals ZSWIM4-6 as a novel BMP signaling modulator. Elife. 2024 Feb 7;13:e80803. doi: 10.7554/eLife.80803. |
Synthesis of Self Permeable Antisense PMO Using C5-Guanidino-Functionalized Pyrimidines at the 5'-End Enables Sox2 Downregulation in Triple Negative Breast Cancer Cells
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Citation:
Mol Pharm. 2024 Feb 7. doi: 10.1021/acs.molpharmaceut.3c00924. Online ahead of print Epub:
Not Epub Abstract:
Delivery of macromolecular drugs inside cells has been a huge challenge in the field of oligonucleotide therapeutics for the... Delivery Method:
base-linked guanidinium Organism or Cell Type:
cell culture: triple-negative breast cancer cell line MDA-MB 231 Citation Extract: Das A, Gupta S, Shaw P, Sinha S. Synthesis of Self Permeable Antisense PMO Using C5-Guanidino-Functionalized Pyrimidines at the 5'-End Enables Sox2 Downregulation in Triple Negative Breast Cancer Cells. Mol Pharm. 2024 Feb 7. doi: 10.1021/acs.molpharmaceut.3c00924. Online ahead of print. |
Genetic association and functional validation of ZFP36L2 in non-syndromic orofacial cleft subtypes
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Citation:
J Hum Genet. 2024. doi:10.1038/s10038-024-01222-z Epub:
Not Epub Abstract:
Background: Non-syndromic orofacial cleft (NSOC) is one of the most common craniofacial malformations with complex etiology.... Organism or Cell Type:
zebrafish Citation Extract: Sun J, Li M, Sun H, Lin Z, Shi B, Jia Z. Genetic association and functional validation of ZFP36L2 in non-syndromic orofacial cleft subtypes. J Hum Genet. 2024. doi:10.1038/s10038-024-01222-z. |
Knockdown of best1 Gene in Zebrafish Caused Abnormal Neuronal and Skeletal Development -A Subtype of Craniovertebral Junction Malformation
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Citation:
Neurospine. 2024 Feb 1. doi: 10.14245/ns.2347238.619. Online ahead of print Epub:
Not Epub Abstract:
Objective: To investigate the developmental defects caused by knockdown of best1 gene in zebrafish as a model for a subtype of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu Z, Li K, Wang K, Zhang L, Jia S, Wang H, Jian F, Wu H. Knockdown of best1 Gene in Zebrafish Caused Abnormal Neuronal and Skeletal Development -A Subtype of Craniovertebral Junction Malformation. Neurospine. 2024 Feb 1. doi: 10.14245/ns.2347238.619. Online ahead of print. |
TANGO2-related rhabdomyolysis symptoms are associated with abnormal autophagy functioning
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Citation:
Autophagy rep. 2024;3(1):[Epub] doi:10.1080/27694127.2024.2306766 Epub:
Not Epub Abstract:
Patients with pathogenic variants in the TANGO2 gene suffer from severe and recurrent rhabdomyolysis episodes precipitated by... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: de Calbiac H, Montealegre S, Straube M, Renault S, Debruge H, Chentout L, Ciura S, Imbard A, Le Guillou E, Marian A, Goudin N, Caccavelli L, Fabrega S, Hubas A, van Endert P, Dupont N, Diana J, Kabashi E, de Lonlay P. TANGO2-related rhabdomyolysis symptoms are associated with abnormal autophagy functioning. Autophagy rep. 2024;3(1):[Epub] doi:10.1080/27694127.2024.2306766. |
Endocardium gives rise to blood cells in zebrafish embryos
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Citation:
Cell Rep. 2024 Feb 1;43(2):113736. doi: 10.1016/j.celrep.2024.113736. Online ahead of print Epub:
Not Epub Abstract:
Previous studies have suggested that the endocardium contributes to hematopoiesis in murine embryos, although definitive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gurung S, Restrepo NK, Sumanas S. Endocardium gives rise to blood cells in zebrafish embryos. Cell Rep. 2024 Feb 1;43(2):113736. doi: 10.1016/j.celrep.2024.113736. Online ahead of print. |
R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient
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Citation:
Nat Commun. 2024 Feb 2;15(1):1003. doi: 10.1038/s41467-024-44951-7 Epub:
Not Epub Abstract:
Establishment of the left-right (LR, sinistral, dextral) body axis in many vertebrate embryos relies on cilia-driven leftward... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lee H, Camuto CM, Niehrs C. R-Spondin 2 governs Xenopus left-right body axis formation by establishing an FGF signaling gradient. Nat Commun. 2024 Feb 2;15(1):1003. doi: 10.1038/s41467-024-44951-7. |
Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis
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Citation:
Front Cell Dev Biol. 2024;12:[Epub ahead of full .pdf] doi:10.3389/fcell.2024.1316048 Epub:
Not Epub Abstract:
Mutations in PRDM15 lead to a syndromic form of holoprosencephaly (HPE) known as Galloway-Mowat syndrome (GAMOS). While a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Saumweber E, Mzoughi S, Khadra A, Werberger A, Schumann S, Guccione E, Schmeisser MJ, Kühl1 SJ. Prdm15 acts upstream of Wnt4 signaling in anterior neural development of Xenopus laevis. Front Cell Dev Biol. 2024;12:[Epub ahead of full .pdf] doi:10.3389/fcell.2024.1316048. |