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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12236 scientific papers returned from the database with the search filters currently being used below.
There are 12236 scientific papers returned from the database with the search filters currently being used below.
Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS)
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Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.01.09.574075 Epub:
Not Epub Abstract:
Okur-Chung Neurodevelopmental Syndrome (OCNDS) is a rare, autosomal dominant disorder caused by heterozygous pathogenic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hassett K, Potu SS, Sankaramoorthy A, Kaneshamoorthy S, Leka K, Huentelman MJ, Narayanan V, Rangasamy S. Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS). bioRxiv. 2024;[preprint] doi:10.1101/2024.01.09.574075. |
Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
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Citation:
Curr Biol. 2024 Jan 8;34(1):171-182.e8. doi: 10.1016/j.cub.2023.11.067. Epub 2023 Dec 21 Epub:
Not Epub Abstract:
Metazoan development relies on the formation and remodeling of cell-cell contacts. Dynamic reorganization of adhesion receptors... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Arslan FN, Hannezo É, Merrin J, Loose M, Heisenberg CP. Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. Curr Biol. 2024 Jan 8;34(1):171-182.e8. doi: 10.1016/j.cub.2023.11.067. Epub 2023 Dec 21. |
amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway
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Citation:
Int J Mol Sci. 2024;25(2):734. doi:10.3390/ijms25020734 Epub:
Not Epub Abstract:
Microtia-atresia is a rare type of congenital craniofacial malformation causing severe damage to the appearance and hearing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun L, Ping L, Fan X, Fan Y, Zhang B, Chen X. amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway. Int J Mol Sci. 2024;25(2):734. doi:10.3390/ijms25020734. |
Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation
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Citation:
Nat Commun. 2024 Jan 8;15(1):365. doi: 10.1038/s41467-023-44611-2 Epub:
Not Epub Abstract:
Accogli A, Shakya S, Yang T, Insinna C, Kim SY, Bell D, Butov KR, Severino M, Niceta M, Scala M, Lee HS, Yoo T, Stauffer J,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gerard A, Potocki L, Rosenfeld JA, Lalani SR, Scott TM, Scott D, Azamian MS, Louie R, Moore HW, Champaigne NL, Hollingsworth G, Torella A, Nigro V, Ploski R, Salpietro V, Zara F, Pizzi S, Chillemi G, Ognibene M, Cooney E, Do J, Linnemann A, Larsen MJ, Specht S, Walters KJ, Choi HJ, Choi M, Tartaglia M, Youkharibache P, Chae JH, Capra V, Park SG, Westlake CJ. Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation. Nat Commun. 2024 Jan 8;15(1):365. doi: 10.1038/s41467-023-44611-2. |
Antagonistic interactions safeguard mitotic propagation of genetic and epigenetic information in zebrafish
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Citation:
Commun Biol. 2024 Jan 5;7(1):31. doi: 10.1038/s42003-023-05692-3 Epub:
Not Epub Abstract:
The stability of cellular phenotypes in developing organisms depends on error-free transmission of epigenetic and genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lawir DF, Soza-Ried C, Iwanami N, Siamishi I, Bylund GO, O Meara C, Sikora K, Kanzler B, Johansson E, Schorpp M, Cauchy P, Boehm T. Antagonistic interactions safeguard mitotic propagation of genetic and epigenetic information in zebrafish. Commun Biol. 2024 Jan 5;7(1):31. doi: 10.1038/s42003-023-05692-3. |
Macrophages inhibit extracellular hyphal growth of A. fumigatus through Rac2 GTPase signaling
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Citation:
Infect Immun. 2024 Jan 3:e0038023. doi: 10.1128/iai.00380-23. Online ahead of print Epub:
Not Epub Abstract:
Macrophages act as a first line of defense against pathogens. Against Aspergillus fumigatus, a fungus with pathogenic potential... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tanner CD, Rosowski EE. Macrophages inhibit extracellular hyphal growth of A. fumigatus through Rac2 GTPase signaling. Infect Immun. 2024 Jan 3:e0038023. doi: 10.1128/iai.00380-23. Online ahead of print. |
Piezo1-dependent regulation of pericyte proliferation by blood flow during brain vascular development
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Citation:
Cell Rep. 2024 Jan 3;43(1):113652. doi: 10.1016/j.celrep.2023.113652. Online ahead of print Epub:
Not Epub Abstract:
Blood flow is known to regulate cerebrovascular development through acting on vascular endothelial cells (ECs). As an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zi H, Peng X, Cao J, Xie T, Liu T, Li H, Bu J, Du J, Li J. Piezo1-dependent regulation of pericyte proliferation by blood flow during brain vascular development. Cell Rep. 2024 Jan 3;43(1):113652. doi: 10.1016/j.celrep.2023.113652. Online ahead of print. |
The RhoGEF Trio is transported by microtubules and affects microtubule stability in migrating neural crest cells
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Citation:
Cells Dev. 2023 Dec 30;177:203899. doi: 10.1016/j.cdev.2023.203899. Online ahead of print Epub:
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Directed cell migration requires a local fine-tuning of Rho GTPase activity to control protrusion formation, cell-cell... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Gossen S, Gerstner S, Borchers A. The RhoGEF Trio is transported by microtubules and affects microtubule stability in migrating neural crest cells. Cells Dev. 2023 Dec 30;177:203899. doi: 10.1016/j.cdev.2023.203899. Online ahead of print. |
Histone lactylation couples cellular metabolism with developmental gene regulatory networks
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Citation:
Nat Commun. 2024 Jan 2;15(1):90. doi: 10.1038/s41467-023-44121-1 Epub:
Not Epub Abstract:
Embryonic cells exhibit diverse metabolic states. Recent studies have demonstrated that metabolic reprogramming drives changes... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Merkuri F, Rothstein M, Simoes-Costa M. Histone lactylation couples cellular metabolism with developmental gene regulatory networks. Nat Commun. 2024 Jan 2;15(1):90. doi: 10.1038/s41467-023-44121-1. |
Development of FKBP5 ASOs to mitigate tau pathology
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Citation:
Alzheimers Dement. 2023;[Epub] doi:10.1002/alz.082780 Epub:
Not Epub Abstract:
Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of abnormal... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: human neuroglioma, mouse hippocampal neuron, mice Citation Extract: Gebru NT, Hill SE, Blair LJ. Development of FKBP5 ASOs to mitigate tau pathology. Alzheimers Dement. 2023;[Epub] doi:10.1002/alz.082780. |