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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Obinutuzumab-Based Drug-Free Macromolecular Therapeutics Synergizes with Topoisomerase Inhibitors
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Citation:
Macromol Biosci. 2023 Oct 15:e2300375. doi: 10.1002/mabi.202300375. Online ahead of print Epub:
Yes Abstract:
Drug-Free Macromolecular Therapeutics (DFMT) utilizes modified monoclonal antibodies (or antibody fragments) to generate... Delivery Method:
cell bathing; injection Organism or Cell Type:
cell culture: Raji (B cells); mice Citation Extract: Gambles MT, Sborov D, Shami P, Yang J, Kopeček J. Obinutuzumab-Based Drug-Free Macromolecular Therapeutics Synergizes with Topoisomerase Inhibitors. Macromol Biosci. 2023 Oct 15:e2300375. doi: 10.1002/mabi.202300375. Online ahead of print. |
Chaperone-mediated autophagy protects against hyperglycemic stress
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Citation:
Autophagy. 2023 Oct 5:[Epub ahead of print]. doi:10.1080/15548627.2023.2267415 Epub:
Yes Abstract:
Chaperone-mediated autophagy (CMA) is a major pathway of lysosomal proteolysis critical for cellular homeostasis and metabolism... Organism or Cell Type:
Oncorhynchus mykiss (rainbow trout) Citation Extract: Vélez EJ, Schnebert S, Goguet M, Balbuena-Pecino S, Dias K, Beauclair L, Fontagné-Dicharry S, Véron V, Depincé A, Beaumatin F, Herpin A, Seiliez I. Chaperone-mediated autophagy protects against hyperglycemic stress. Autophagy. 2023 Oct 5:[Epub ahead of print]. doi:10.1080/15548627.2023.2267415. |
Modeling of large-scale hoxbb cluster deletions in zebrafish uncovers a role for segmentation pathways in atrioventricular boundary specification
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Citation:
Cell Mol Life Sci. 2023;80:317. doi:10.1007/s00018-023-04933-2 Epub:
Not Epub Abstract:
Hox genes orchestrate the segmental specification of the muscular circulatory system in invertebrates but it has not proven... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu P, Wang B, Jin D, Gu Y, He H, Meng X, Zhu W, Chiang DY, Li W, MacRae CA, Zu Y. Modeling of large-scale hoxbb cluster deletions in zebrafish uncovers a role for segmentation pathways in atrioventricular boundary specification. Cell Mol Life Sci. 2023;80:317. doi:10.1007/s00018-023-04933-2. |
An in vivo drug screen reveals that cyclooxygenase 2-derived prostaglandin D2 promotes spinal cord neurogenesis
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.10.05.561099 Epub:
Not Epub Abstract:
The study of neurogenesis is essential to understand fundamental developmental processes and for the development of cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: González-Llera L, Sobrido-Cameán D, Quelle-Regaldie A, Sánchez L, Barreiro-Iglesias A. An in vivo drug screen reveals that cyclooxygenase 2-derived prostaglandin D2 promotes spinal cord neurogenesis. bioRxiv. 2023;[preprint] doi:10.1101/2023.10.05.561099. |
P29 DMD transcript imbalance and nuclear trafficking evaluation in muscle biopsies from baseline and golodirsen treated 4053-101 clinical trial patients
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Citation:
Neuromuscul Disord. 2023;33(Supp 1):S104. doi:10.1016/j.nmd.2023.07.156 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is an X-linked, rare, neuromuscular disease caused by mutations in the DMD gene affecting its... Delivery Method:
intravenous (i.v.) infusion Organism or Cell Type:
human Citation Extract: Rossi R, Singh S, Torelli S, Catapano F, Chambers D, Morgan J, Malhotra J, Muntoni F. P29 DMD transcript imbalance and nuclear trafficking evaluation in muscle biopsies from baseline and golodirsen treated 4053-101 clinical trial patients. Neuromuscul Disord. 2023;33(Supp 1):S104. doi:10.1016/j.nmd.2023.07.156. |
P23 Evaluation of safety parameters and dystrophin expression by sequential administration of exon-skipping and gene therapy in a DMDmdx mouse model
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Citation:
Neuromuscul Disord. 2023;33(Supp 1):S102-3. doi:10.1016/j.nmd.2023.07.150 Epub:
Not Epub Abstract:
There are promising treatment approaches emerging for Duchenne muscular dystrophy (DMD): exon skipping with peptide-conjugated... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Potter R, Cooper Olson GC, Smith L, Greve J, Haile A, Wier C, Snedeker J, Burch P, Hunter B, Malmberg A, Rodino-Klapac L. P23 Evaluation of safety parameters and dystrophin expression by sequential administration of exon-skipping and gene therapy in a DMDmdx mouse model. Neuromuscul Disord. 2023;33(Supp 1):S102-3. doi:10.1016/j.nmd.2023.07.150. |
Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon
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Citation:
Development. 2003 Oct;130(20):4881-93. doi: 10.1242/dev.00683. Epub 2003 Aug 13 Epub:
Not Epub Abstract:
Specification of the forebrain, midbrain and hindbrain primordia occurs during gastrulation in response to signals that pattern... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Scholpp S, Lohs C, Brand M. Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon. Development. 2003 Oct;130(20):4881-93. doi: 10.1242/dev.00683. Epub 2003 Aug 13. |
SAT066 Leukotriene B4 Receptor 2 Mediates Macrophage Migration To Injured β Cells
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Citation:
J Endocrinol 2023;7(Supp1):bvad114.933. doi:10.1210/jendso/bvad114.933 Epub:
Not Epub Abstract:
Type 1 diabetes (T1D) is an autoimmune disease, characterized in part by islet inflammation and macrophage infiltration leading... Organism or Cell Type:
zebrafish Citation Extract: Ermis E, Nargis T, Kulkarni A, May S, Tersey SA, Mirmira RG, Anderson RM. SAT066 Leukotriene B4 Receptor 2 Mediates Macrophage Migration To Injured β Cells. J Endocrinol 2023;7(Supp1):bvad114.933. doi:10.1210/jendso/bvad114.933. |
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling
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Citation:
Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z Epub:
Not Epub Abstract:
The relative abundance of Wnt receptors plays a crucial role in controlling Wnt signaling in tissue homeostasis and human... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ng VH, Spencer Z, Neitzel LR, Nayak A, Loberg MA, Shen C, Kassel SN, Kroh HK, An Z, Anthony CC, Bryant JM, Lawson A, Goldsmith L, Benchabane H, Hansen AG, Li J, D'Souza S, Lebensohn AM, Rohatgi R, Weiss WA, Weiss VL, Williams C, Hong CC, Robbins DJ, Ahmed Y, Lee E. The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. Nat Commun. 2023 Oct 5;14(1):6173. doi: 10.1038/s41467-023-41836-z. |
Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation
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Citation:
Sci Rep. 2023 Oct 4;13(1):16671. doi: 10.1038/s41598-023-43662-1 Epub:
Not Epub Abstract:
The nephron, functional unit of the vertebrate kidney, is specialized in metabolic wastes excretion and body fluids... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Cervino AS, Collodel MG, Lopez IA, Roa C, Hochbaum D, Hukriede NA, Cirio MC. Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation. Sci Rep. 2023 Oct 4;13(1):16671. doi: 10.1038/s41598-023-43662-1. |