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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis
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Citation:
Cells. 2023;12:2379. doi:10.3390/cells12192379 Epub:
Not Epub Abstract:
Purines are required for fundamental biological processes and alterations in their metabolism lead to severe genetic diseases... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Duperray M, Hardet F, Henriet E, Saint-Marc C, Boué-Grabot E, Daignan-Fornier B, Massé K, Pinson B. Purine Biosynthesis Pathways Are Required for Myogenesis in Xenopus laevis. Cells. 2023;12:2379. doi:10.3390/cells12192379 . |
A digital twin reproducing gene regulatory network dynamics of early Ciona embryos indicates robust buffers in the network
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Citation:
PLoS Genet. 2023 Sep 27;19(9):e1010953. doi: 10.1371/journal.pgen.1010953. eCollection 2023 Sep Epub:
Not Epub Abstract:
How gene regulatory networks (GRNs) encode gene expression dynamics and how GRNs evolve are not well understood, although these... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Tokuoka M, Satou Y. A digital twin reproducing gene regulatory network dynamics of early Ciona embryos indicates robust buffers in the network. PLoS Genet. 2023 Sep 27;19(9):e1010953. doi: 10.1371/journal.pgen.1010953. eCollection 2023 Sep. |
Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension
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Citation:
eLife. 2023;12:RP91199 doi:10.7554/eLife.91199.1 Epub:
Not Epub Abstract:
Convergent extension (CE) is a fundamental morphogenetic process where oriented cell behaviors lead to polarized extension of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Seo H-s, Yu D, Popov I, Tao J, Angermeier A, Sha B, Axelrod J, Chang C, Wang J. Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension. eLife. 2023;12:RP91199 doi:10.7554/eLife.91199.1. |
A bioelectrical phase transition patterns the first vertebrate heartbeats
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Citation:
Nature. 2023 Sep 27. doi: 10.1038/s41586-023-06561-z. Online ahead of print Epub:
Yes Abstract:
A regular heartbeat is essential to vertebrate life. In the mature heart, this function is driven by an anatomically localized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jia BZ, Qi Y, Wong-Campos JD, Megason SG, Cohen AE. A bioelectrical phase transition patterns the first vertebrate heartbeats. Nature. 2023 Sep 27. doi: 10.1038/s41586-023-06561-z. Online ahead of print. |
Lymphatic Defects in Zebrafish sox18 Mutants Are Exacerbated by Perturbed VEGFC Signaling, While Masked by Elevated sox7 Expression
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Citation:
Cells. 2023 Sep 19;12(18):2309. doi: 10.3390/cells12182309 Epub:
Not Epub Abstract:
Mutations in the transcription factor-coding gene SOX18, the growth factor-coding gene VEGFC and its receptor-coding gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Moleri S, Mercurio S, Pezzotta A, D'Angelo D, Brix A, Plebani A, Lini G, Di Fuorti M, Beltrame M. Lymphatic Defects in Zebrafish sox18 Mutants Are Exacerbated by Perturbed VEGFC Signaling, While Masked by Elevated sox7 Expression. Cells. 2023 Sep 19;12(18):2309. doi: 10.3390/cells12182309. |
Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in Adipocytes
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Citation:
Int J Mol Sci. 2023 Sep 20;24(18):14324. doi: 10.3390/ijms241814324 Epub:
Not Epub Abstract:
Type 2 diabetes mellitus is a chronic metabolic disease with no cure. Adipose tissue is a major site of systemic insulin... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human diabetic pre-adipocytes Citation Extract: Lui A, Patel RS, Krause-Hauch M, Sparks RP, Patel NA. Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in Adipocytes. Int J Mol Sci. 2023 Sep 20;24(18):14324. doi: 10.3390/ijms241814324. |
Hand2 represses non-cardiac cell fates through chromatin remodeling at cis-regulatory elements
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.09.23.559156 Epub:
Not Epub Abstract:
Developmental studies have revealed the importance of the transcription factor Hand2 in cardiac development. Hand2 promotes... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Komatsu V, Cooper B, Yim P, Chan K, Gong W, Wheatley L, Rohs R, Fraser SE, Trinh LA. Hand2 represses non-cardiac cell fates through chromatin remodeling at cis-regulatory elements. bioRxiv. 2023;[preprint] doi:10.1101/2023.09.23.559156. |
Defective quality control autophagy in Hyperhomocysteinemia promotes ER stress and consequent neuronal apoptosis through proteotoxicity
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Citation:
Cell Commun Signal. 2023 Sep 25;21(1):258. doi: 10.1186/s12964-023-01288-w Epub:
Not Epub Abstract:
Homocysteine (Hcy), produced physiologically in all cells, is an intermediate metabolite of methionine and cysteine metabolism... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kaur B, Sharma PK, Chatterjee B, Bissa B, Nattarayan V, Ramasamy S, Bhat A, Lal M, Samaddar S, Banerjee S, Roy SS. Defective quality control autophagy in Hyperhomocysteinemia promotes ER stress and consequent neuronal apoptosis through proteotoxicity. Cell Commun Signal. 2023 Sep 25;21(1):258. doi: 10.1186/s12964-023-01288-w. |
Role of microRNAs and their downstream target transcription factors in zebrafish thrombopoiesis
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Citation:
Sci Rep. 2023 Sep 26;13(1):16066. doi: 10.1038/s41598-023-42868-7 Epub:
Not Epub Abstract:
Previous studies have shown that human platelets and megakaryocytes carry microRNAs suggesting their role in platelet function... Delivery Method:
Vivo-Morpholino piggyback Organism or Cell Type:
zebrafish Citation Extract: Al Qaryoute A, Fallatah W, Dhinoja S, Raman R, Jagadeeswaran P. Role of microRNAs and their downstream target transcription factors in zebrafish thrombopoiesis. Sci Rep. 2023 Sep 26;13(1):16066. doi: 10.1038/s41598-023-42868-7. |
Maintenance of pluripotency-like signature in the entire ectoderm leads to neural crest stem cell potential
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Citation:
Nat Commun. 2023 Sep 23;14(1):5941. doi: 10.1038/s41467-023-41384-6 Epub:
Not Epub Abstract:
The ability of the pluripotent epiblast to contribute progeny to all three germ layers is thought to be lost after gastrulation... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Pajanoja C, Hsin J, Olinger B, Schiffmacher A, Yazejian R, Abrams S, Dapkunas A, Zainul Z, Doyle AD, Martin D, Kerosuo L. Maintenance of pluripotency-like signature in the entire ectoderm leads to neural crest stem cell potential. Nat Commun. 2023 Sep 23;14(1):5941. doi: 10.1038/s41467-023-41384-6. |