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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry

Authors:
Karasawa K, Duchoslav E, Burton L, Kawakami J, Baba T
Citation:
Anal Chem. 2023 Oct 23. doi: 10.1021/acs.analchem.3c03621. Online ahead of print
Epub:
Yes
Abstract:
We report the first sequencing of morpholino antisense oligonucleotides (phosphorodiamidate morpholino oligomers, PMOs) using...
Link:
https://pubs.acs.org/doi/10.1021/acs.analchem.3c03621
Citation Extract:
Karasawa K, Duchoslav E, Burton L, Kawakami J, Baba T. Sequencing of Morpholino Antisense Oligonucleotides Using Electron Capture Dissociation Mass Spectrometry. Anal Chem. 2023 Oct 23. doi: 10.1021/acs.analchem.3c03621. Online ahead of print.

Specific CaMKIIs mediate convergent extension cell movements in early zebrafish development

Authors:
McLeod JJ, Rothschild SC, Francescatto L, Kim H, Tombes RM
Citation:
Dev Dyn. 2023 Oct 20. doi: 10.1002/dvdy.665. Online ahead of print
Epub:
Yes
Abstract:
Background: Noncanonical Wnts are morphogens that can elevate intracellular Ca2+ , activate the Ca2+ /calmodulin-dependent...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.665
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McLeod JJ, Rothschild SC, Francescatto L, Kim H, Tombes RM. Specific CaMKIIs mediate convergent extension cell movements in early zebrafish development. Dev Dyn. 2023 Oct 20. doi: 10.1002/dvdy.665. Online ahead of print.

Zmym4 is required for early cranial gene expression and craniofacial cartilage formation

Authors:
Jourdeuil K, Neilson KM, Cousin H, Tavares ALP, Majumdar HD, Alfandari D, Moody SA
Citation:
Front Cell Dev Biol. 2023 Oct 3;11:1274788. doi: 10.3389/fcell.2023.1274788. eCollection 2023
Epub:
Not Epub
Abstract:
Introduction: The Six1 transcription factor plays important roles in the development of cranial sensory organs, and point...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2023.1274788/full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Jourdeuil K, Neilson KM, Cousin H, Tavares ALP, Majumdar HD, Alfandari D, Moody SA. Zmym4 is required for early cranial gene expression and craniofacial cartilage formation. Front Cell Dev Biol. 2023 Oct 3;11:1274788. doi: 10.3389/fcell.2023.1274788. eCollection 2023.

Two novel CHN1 variants identified in Duane retraction syndrome pedigrees disrupt development of ocular motor nerves in zebrafish

Authors:
Zhang R, Jia H, Chang Q, Zhang Z, Peng C, Ma Q, Liang Y, Yang S, Jiao Y
Citation:
J Hum Genet. 2023;[Epub ahead of print] doi:10.1038/s10038-023-01201-w
Epub:
Yes
Abstract:
Duane retraction syndrome (DRS) is a rare congenital eye movement disorder causing by the dysplasia of abducens nerve, and has...
Link:
https://www.nature.com/articles/s10038-023-01201-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang R, Jia H, Chang Q, Zhang Z, Peng C, Ma Q, Liang Y, Yang S, Jiao Y. Two novel CHN1 variants identified in Duane retraction syndrome pedigrees disrupt development of ocular motor nerves in zebrafish. J Hum Genet. 2023;[Epub ahead of print] doi:10.1038/s10038-023-01201-w.

Ciliary localization of a light-activated neuronal GPCR shapes behavior

Authors:
Winans AM, Friedmann D, Stanley C, Xiao T, Liu TL, Chang CJ, Isacoff EY
Citation:
Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2311131120. doi: 10.1073/pnas.2311131120. Epub 2023 Oct 16
Epub:
Not Epub
Abstract:
Many neurons in the central nervous system produce a single primary cilium that serves as a specialized signaling organelle....
Link:
https://www.pnas.org/doi/10.1073/pnas.2311131120
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Winans AM, Friedmann D, Stanley C, Xiao T, Liu TL, Chang CJ, Isacoff EY. Ciliary localization of a light-activated neuronal GPCR shapes behavior. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2311131120. doi: 10.1073/pnas.2311131120. Epub 2023 Oct 16.

A novel role for the chloride intracellular channel protein Clic5 in ciliary function

Authors:
Ott E, Hoff S, Indorf L, Ditengou FA, Müller J, Renschler G, Lienkamp SS, Kramer-Zucker A, Bergmann C, Epting D
Citation:
Sci Rep. 2023 Oct 17;13(1):17647. doi: 10.1038/s41598-023-44235-y
Epub:
Not Epub
Abstract:
CLIC5 belongs to a family of ion channels with six members reported so far. In vertebrates, the CLIC5 gene encodes two...
Link:
https://www.nature.com/articles/s41598-023-44235-y
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ott E, Hoff S, Indorf L, Ditengou FA, Müller J, Renschler G, Lienkamp SS, Kramer-Zucker A, Bergmann C, Epting D. A novel role for the chloride intracellular channel protein Clic5 in ciliary function. Sci Rep. 2023 Oct 17;13(1):17647. doi: 10.1038/s41598-023-44235-y.

Xbra modulates the activity of linker region phosporlated Smad1 during Xenopus somitogenesis

Authors:
Kim J, Kumar S, Umair Z, Goutam RS, Lee U
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.10.11.561863
Epub:
Not Epub
Abstract:
The Bmp/Smad1 pathway plays a crucial role in developmental processes and tissue homeostasis. Mitogen-activated protein kinase...
Link:
https://www.biorxiv.org/content/10.1101/2023.10.11.561863v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kim J, Kumar S, Umair Z, Goutam RS, Lee U. Xbra modulates the activity of linker region phosporlated Smad1 during Xenopus somitogenesis. bioRxiv. 2023;[preprint] doi:10.1101/2023.10.11.561863.

Rtf1-dependent transcriptional pausing regulates cardiogenesis

Authors:
Langenbacher AD, Fei Lu, Tsang L, Yi Z, Huang S, Keer B, Tian X, Eide A, Pellegrini M, Nakano H, Nakano A, Chen J-N
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.10.13.562296
Epub:
Not Epub
Abstract:
During heart development, a well-characterized network of transcription factors initiates cardiac gene expression and defines...
Link:
https://www.biorxiv.org/content/10.1101/2023.10.13.562296v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langenbacher AD, Fei Lu, Tsang L, Yi Z, Huang S, Keer B, Tian X, Eide A, Pellegrini M, Nakano H, Nakano A, Chen J-N. Rtf1-dependent transcriptional pausing regulates cardiogenesis. bioRxiv. 2023;[preprint] doi:10.1101/2023.10.13.562296.

Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G-Clamp Analogs

Authors:
Das A, Ghosh A, Kundu J, Egli M, Manoharan M, Sinha S
Citation:
J Org Chem. 2023 Oct 16. doi: 10.1021/acs.joc.3c01658. Online ahead of print
Epub:
Yes
Abstract:
Successful syntheses of chlorophosphoramidate morpholino monomers containing tricyclic cytosine analogs phenoxazine, G-clamp,...
Link:
https://pubs.acs.org/doi/10.1021/acs.joc.3c01658
Citation Extract:
Das A, Ghosh A, Kundu J, Egli M, Manoharan M, Sinha S. Synthesis and Biophysical Studies of High-Affinity Morpholino Oligomers Containing G-Clamp Analogs. J Org Chem. 2023 Oct 16. doi: 10.1021/acs.joc.3c01658. Online ahead of print.

Crb3 is required to organize the apical domain of multiciliated cells

Authors:
Burcklé C, Raitière J, Michaux G, Kodjabachian L, Bivic AL
Citation:
J Cell Sci. 2023 Oct 16:jcs.261046. doi: 10.1242/jcs.261046. Online ahead of print
Epub:
Yes
Abstract:
Cell shape changes mainly rely on the remodeling of the actin cytoskeleton. Multiciliated cells (MCCs) of the mucociliary...
Link:
https://journals.biologists.com/jcs/article-abstract/doi/10.1242/jcs.261046/333513/Crb3-is-required-to-organize-the-apical-domain-of
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Burcklé C, Raitière J, Michaux G, Kodjabachian L, Bivic AL. Crb3 is required to organize the apical domain of multiciliated cells. J Cell Sci. 2023 Oct 16:jcs.261046. doi: 10.1242/jcs.261046. Online ahead of print.

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