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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Zinc finger protein 365 is a new maternal LPS-binding protein that defends zebrafish embryos against gram-negative bacterial infections
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Citation:
FASEB J. 2017 Oct 17. pii: fj.201700694R. doi: 10.1096/fj.201700694R. [Epub ahead of print] Epub:
Yes Abstract:
Zinc finger protein 365 (ZNF365) is widespread in animals, but its function and mechanism remains poorly defined. Here we... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Du X, Zhou Y, Song L, Wang X, Zhang S. Zinc finger protein 365 is a new maternal LPS-binding protein that defends zebrafish embryos against gram-negative bacterial infections. FASEB J. 2017 Oct 17. pii: fj.201700694R. doi: 10.1096/fj.201700694R. [Epub ahead of print]. |
Wilms tumor protein-dependent transcription of VEGF receptor 2 and hypoxia regulate expression of the testis-promoting gene Sox9 in murine embryonic gonads
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Citation:
J Biol Chem. 2017 Dec 8;292(49):20281-20291. doi: 10.1074/jbc.M117.816751. Epub 2017 Oct 17. Epub:
Not Epub Abstract:
The Wilms tumor protein 1 (WT1) has been implicated in the control of several genes in sexual development, but its function in... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
explant culture: murine gonads, kidneys Citation Extract: Kirschner KM, Sciesielski LK, Krueger K, Scholz H. Wilms tumor protein-dependent transcription of VEGF receptor 2 and hypoxia regulate expression of the testis-promoting gene Sox9 in murine embryonic gonads. J Biol Chem. 2017 Dec 8;292(49):20281-20291. doi: 10.1074/jbc.M117.816751. Epub 2017 Oct 17.. |
Cdc42 regulates the cellular localization of Cdc42ep1 in controlling neural crest cell migration
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Citation:
J Mol Cell Biol. 2017 Oct 6. doi: 10.1093/jmcb/mjx044. [Epub ahead of print] Epub:
Yes Abstract:
The member of Rho family of small GTPases Cdc42 plays important and conserved roles in cell polarity and motility. The Cdc42ep... Citation Extract: Shlomi C, Kovari DT, Wei W, Keate R, Curtis JE, Nie S. Cdc42 regulates the cellular localization of Cdc42ep1 in controlling neural crest cell migration. J Mol Cell Biol. 2017 Oct 6. doi: 10.1093/jmcb/mjx044. [Epub ahead of print]. |
Guidelines for morpholino use in zebrafish
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Citation:
PLoS Genet. 2017 Oct 19;13(10):e1007000. doi: 10.1371/journal.pgen.1007000. eCollection 2017 Oct Epub:
Not Epub Abstract:
No abstract available. Organism or Cell Type:
zebrafish Citation Extract: Stainier DYR, Raz E, Lawson ND, Ekker SC, Burdine RD, Eisen JS, Ingham PW, Schulte-Merker S, Yelon D, Weinstein BM, Mullins MC, Wilson SW, Ramakrishnan L, Amacher SL, Neuhauss SCF, Meng A, Mochizuki N, Panula P, Moens CB. Guidelines for morpholino use in zebrafish. PLoS Genet. 2017 Oct 19;13(10):e1007000. doi: 10.1371/journal.pgen.1007000. eCollection 2017 Oct. |
Ottogi Inhibits Wnt/β-catenin Signaling by Regulating Cell Membrane Trafficking of Frizzled8
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Citation:
Sci Rep. 2017 Oct 16;7(1):13278. doi: 10.1038/s41598-017-13429-6 Epub:
Not Epub Abstract:
Wnt signaling controls critical developmental processes including tissue/body patterning. Here we report the identification of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim HT, Lee MS, Jeong YM, Ro H, Kim DI, Shin YH, Kim JE, Hwang KS, Choi JH, Bahn M, Lee JJ, Lee SH, Bae YK, Lee JS, Choi JK, Kim NS, Yeo CY, Kim CH. Ottogi Inhibits Wnt/β-catenin Signaling by Regulating Cell Membrane Trafficking of Frizzled8. Sci Rep. 2017 Oct 16;7(1):13278. doi: 10.1038/s41598-017-13429-6. |
Myoblasts and macrophages are required for therapeutic morpholino antisense oligonucleotide delivery to dystrophic muscle
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Citation:
Nat Commun. 2017 Oct 16;8(1):941. doi: 10.1038/s41467-017-00924-7 Epub:
Not Epub Abstract:
Exon skipping is a promising therapeutic strategy for Duchenne muscular dystrophy (DMD), employing morpholino antisense... Delivery Method:
injection, retro-orbital Organism or Cell Type:
Mice, C57Bl/10ScSn-mdx/J or C57Bl/10ScSnJ (Bl10 or wild-type) Citation Extract: Novak JS, Hogarth MW, Boehler JF, Nearing M, Vila MC, Heredia R, Fiorillo AA, Zhang A, Hathout Y, Hoffman EP, Jaiswal JK, Nagaraju K, Cirak S, Partridge TA. Myoblasts and macrophages are required for therapeutic morpholino antisense oligonucleotide delivery to dystrophic muscle. Nat Commun. 2017 Oct 16;8(1):941. doi: 10.1038/s41467-017-00924-7. |
Ultrafine Particles Exposure Reveals the Importance of FOXO1/Notch Activation Complex for Vascular Regeneration
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Citation:
Antioxid Redox Signal. 2017 Oct 17. doi: 10.1089/ars.2017.7166. [Epub ahead of print] Epub:
Yes Abstract:
AIMS: Redox active ultrafine particles (UFP, d < 0.2 µm) promote vascular oxidative stress and atherosclerosis. Notch... Organism or Cell Type:
zebrafish Citation Extract: Baek KI, Packard RR, Hsu JJ, Saffari A, Ma Z, Luu AP, Pietersen A, Yen H, Ren B, Ding Y, Sioutas C, Li R, Hsiai TK. Ultrafine Particles Exposure Reveals the Importance of FOXO1/Notch Activation Complex for Vascular Regeneration. Antioxid Redox Signal. 2017 Oct 17. doi: 10.1089/ars.2017.7166. [Epub ahead of print]. |
hace1 influences zebrafish cardiac development via ROS-dependent mechanisms
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Citation:
Dev Dyn. 2017 Oct 11. doi: 10.1002/dvdy.24600. [Epub ahead of print] Epub:
Yes Abstract:
BACKGROUND: In this study we reveal a previously undescribed role of the HACE1 (HECT domain and Ankyrin repeat Containing E3... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Razaghi B, Steele SL, Prykhozhij SV, Stoyek MR, Hill JA, Cooper MD, McDonald L, Lin W, Daugaard M, Crapoulet N, Chacko S, Lewis S, Scott IC, Sorensen PHB, Berman JN. hace1 influences zebrafish cardiac development via ROS-dependent mechanisms. Dev Dyn. 2017 Oct 11. doi: 10.1002/dvdy.24600. [Epub ahead of print]. |
An amphipathic trans-acting phosphorothioate RNA element delivers an uncharged phosphorodiamidate morpholino sequence in mdx mouse myotubes
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Citation:
RSC Adv. 2017;7:42519-42528. doi: 10.1039/C7RA04247G. Epub 2017 Sep 4 Epub:
Not Epub Abstract:
An efficient method for the delivery of uncharged polyA-tailed phosphorodiamidate morpholino sequences (PMO) in mammalian cells... Delivery Method:
complementary phosphorothioate oligo Organism or Cell Type:
cell culture: HeLa pLuc705, mdx myotubes Citation Extract: Jain HV, Boehler JF, Verthelyi D, Nagaraju K, Beaucage SL. An amphipathic trans-acting phosphorothioate RNA element delivers an uncharged phosphorodiamidate morpholino sequence in mdx mouse myotubes. RSC Adv. 2017;7:42519-42528. doi: 10.1039/C7RA04247G. Epub 2017 Sep 4. |
Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of mesendoderm tissue at gastrulation
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Citation:
Development. 2017 Oct 5. pii: dev.155200. doi: 10.1242/dev.155200. [Epub ahead of print] Epub:
Yes Abstract:
Coordination of individual cell behaviors is a critical step in the assembly and morphogenesis of tissues. Xenopus mesendoderm... Organism or Cell Type:
Xenopus Citation Extract: Sonavane PR, Wang C, Dzamba B, Weber GF, Periasamy A, DeSimone DW. Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of mesendoderm tissue at gastrulation. Development. 2017 Oct 5. pii: dev.155200. doi: 10.1242/dev.155200. [Epub ahead of print]. |