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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin
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Citation:
Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print] Epub:
Not Epub Abstract:
Germ-layer formation during gastrulation is both a fundamental step of development and a paradigm for tissue formation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Giger FA, David NB. Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin. Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print]. |
A right-handed signalling pathway drives heart looping in vertebrates
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Citation:
Nature. 2017;549:86-90. doi:doi:10.1038/nature23454 Epub:
Not Epub Abstract:
Most animals show external bilateral symmetry, which hinders the observation of multiple internal left–right (L/R) asymmetries... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ocaña OH, Coskun H, Minguillón C, Murawala P, Tanaka AM, Galcerán J, Muñoz-Chápuli R, Nieto MA. A right-handed signalling pathway drives heart looping in vertebrates. Nature. 2017;549:86-90. doi:doi:10.1038/nature23454. |
NQO2 inhibition relieves ROS effects on mouse oocyte meiotic maturation and embryo development
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Citation:
Biol Reproduc. 2017;[Accepted manuscript] doi:10.1093/biolre/iox098 Epub:
Yes Abstract:
NRH: quinone oxidoreductase 2 (NQO2) is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron... Organism or Cell Type:
mouse oocyte Citation Extract: Chen D, Li X, Xiaoyun Liu X, Liu X, Jiang X, Du J, Wang Q, Liang Y, Ma W. NQO2 inhibition relieves ROS effects on mouse oocyte meiotic maturation and embryo development. Biol Reproduc. 2017;[Accepted manuscript] doi:10.1093/biolre/iox098. |
A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants
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Citation:
Sci Rep. 2017 Sep 4;7(1):10381. doi: 10.1038/s41598-017-10968-w Epub:
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Conventional genetic screens for recessive mutants are inadequate for studying biological processes in the adult vertebrate due... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ma Z, Zhu P, Pang M, Guo L, Chang N, Zheng J, Zhu X, Gao C, Huang H, Cui Z, Xiong JW, Peng J, Chen J. A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants. Sci Rep. 2017 Sep 4;7(1):10381. doi: 10.1038/s41598-017-10968-w. |
Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina
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Citation:
Neural Dev. 2017 Sep 1;12(1):16. doi: 10.1186/s13064-017-0093-2 Epub:
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BACKGROUND: Amacrine interneurons that modulate synaptic plasticity between bipolar and ganglion cells constitute the most... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Bessodes N, Parain K, Bronchain O, Bellefroid EJ, Perron M. Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina. Neural Dev. 2017 Sep 1;12(1):16. doi: 10.1186/s13064-017-0093-2. |
Amphiphilic lipopeptide significantly enhances uptake of charge-neutral splice switching morpholino oligonucleotide in spinal muscular atrophy patient-derived fibroblasts
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Citation:
Int J Pharmaceutics. 2017;[Epub ahead of print] doi:10.1016/j.ijpharm.2017.08.116 Epub:
Yes Abstract:
Splice-switching antisense oligonucleotides (SSOs) are emerging therapeutics with two SSOs recently approved by the FDA for... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: patient-derived SMA fibroblasts Citation Extract: Tajik-Ahmadabad B, Polyzos A, Separovic F, Shabanpoor F. Amphiphilic lipopeptide significantly enhances uptake of charge-neutral splice switching morpholino oligonucleotide in spinal muscular atrophy patient-derived fibroblasts. Int J Pharmaceutics. 2017;[Epub ahead of print] doi:10.1016/j.ijpharm.2017.08.116. |
Neurotransmitter Switching Regulated by miRNAs Controls Changes in Social Preference
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Citation:
Neuron. 2017;95:1-15. doi:j.neuron.2017.08.023 Epub:
Not Epub Abstract:
Changes in social preference of amphibian larvae result from sustained exposure to kinship odorants. To understand the... Delivery Method:
electroporation Organism or Cell Type:
Xenopus laevis Citation Extract: Dulcis D, Lippi G, Stark CJ, Do LH, Berg DK, Spitzer NC. Neurotransmitter Switching Regulated by miRNAs Controls Changes in Social Preference. Neuron. 2017;95:1-15. doi:j.neuron.2017.08.023. |
MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus
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Citation:
PLoS Genet. 2017 Aug 31;13(8):e1006957. doi: 10.1371/journal.pgen.1006957. [Epub ahead of print] Epub:
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Deletions at chromosome 2p25.3 are associated with a syndrome consisting of intellectual disability and obesity. The smallest... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Blanchet P, Bebin M, Bruet S, Cooper GM, Thompson ML, Duban-Bedu B, Gerard B, Piton A, Suckno S, Deshpande C, Clowes V, Vogt J, Turnpenny P, Williamson MP, Alembik Y; Clinical Sequencing Exploratory Research Study Consortium; Deciphering Developmental Disorders Consortium, Glasgow E, McNeill A. MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus. PLoS Genet. 2017 Aug 31;13(8):e1006957. doi: 10.1371/journal.pgen.1006957. [Epub ahead of print]. |
Functional validation of novel MKS3/TMEM67 mutations in COACH syndrome
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Citation:
Sci Rep. 2017;7:10222. doi:10.1038/s41598-017-10652-z Epub:
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COACH syndrome is an autosomal recessive developmental disorder, a subtype of Joubert syndrome and related disorders,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee S-H, Nam T-S, Li W, Kim JH, Yoon W, Choi Y-D, Kim K-H, Cai H, Kim MJ, Kim C, Choy HE, Kim N, Chay KO, Kim M-K, Choi S-Y. Functional validation of novel MKS3/TMEM67 mutations in COACH syndrome. Sci Rep. 2017;7:10222. doi:10.1038/s41598-017-10652-z. |
RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
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Citation:
Neuron. 2017 Aug 16;95(4):852-868.e8. doi: 10.1016/j.neuron.2017.07.016. Epub 2017 Aug 3 Epub:
Not Epub Abstract:
Nascent proteins can be positioned rapidly at precise subcellular locations by local protein synthesis (LPS) to facilitate... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Wong HH, Lin JQ, Ströhl F, Roque CG, Cioni JM, Cagnetta R, Turner-Bridger B, Laine RF, Harris WA, Kaminski CF, Holt CE. RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo. Neuron. 2017 Aug 16;95(4):852-868.e8. doi: 10.1016/j.neuron.2017.07.016. Epub 2017 Aug 3. |