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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model
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Citation:
Int J Cancer. 2017;[Accepted Manuscript] doi10.1002/ijc.31075 Epub:
Yes Abstract:
The protein bcl-xL is able to enhance the secretion of the pro-inflammatory chemokine interleukin 8 (CXCL8) in human melanoma... Organism or Cell Type:
zebrafish Citation Extract: Gabellini C, Gómez-Abenza E, Ibáñez-Molero S, Tupone MG, Pérez-Oliva AB, de Oliveira S, Del Bufalo D, Mulero V. Interleukin 8 mediates bcl-xL-induced enhancement of human melanoma cell dissemination and angiogenesis in a zebrafish xenograft model. Int J Cancer. 2017;[Accepted Manuscript] doi10.1002/ijc.31075. |
Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I
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Citation:
Nat Comm. 2017;8:694. doi:10.1038/s41467-017-00774-3 Epub:
Not Epub Abstract:
A key feature of meiosis is the step-wise removal of cohesin, the protein complex holding sister chromatids together, first... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: El Yakoubi W, Buffin E, Cladière D, Gryaznova Y, Berengue I, Touati SA, Gómez R, Suja JA, van Deursen JM, Wassmann K. Mps1 kinase-dependent Sgo2 centromere localisation mediates cohesin protection in mouse oocyte meiosis I. Nat Comm. 2017;8:694. doi:10.1038/s41467-017-00774-3. |
Bacterial DnaB helicase interacts with the excluded strand to regulate unwinding
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Citation:
J Biol Chem. 2017 Sep 22. pii: jbc.M117.814178. doi: 10.1074/jbc.M117.814178. [Epub ahead of print] Epub:
Yes Abstract:
Replicative hexameric helicases are thought to unwind duplex DNA by steric exclusion (SE), where one DNA strand is encircled by... Citation Extract: Carney SM, Gomathinayagam S, Leuba SH, Trakselis MA. Bacterial DnaB helicase interacts with the excluded strand to regulate unwinding. J Biol Chem. 2017 Sep 22. pii: jbc.M117.814178. doi: 10.1074/jbc.M117.814178. [Epub ahead of print]. |
Cohesin acetyltransferase Esco2 regulates SAC and kinetochore functions via maintaining H4K16 acetylation during mouse oocyte meiosis
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Citation:
Nucleic Acids Res. 2017 Sep 19;45(16):9388-9397. doi: 10.1093/nar/gkx563 Epub:
Not Epub Abstract:
Sister chromatid cohesion, mediated by cohesin complex and established by the acetyltransferases Esco1 and Esco2, is essential... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Lu Y, Dai X, Zhang M, Miao Y, Zhou C, Cui Z, Xiong B. Cohesin acetyltransferase Esco2 regulates SAC and kinetochore functions via maintaining H4K16 acetylation during mouse oocyte meiosis. Nucleic Acids Res. 2017 Sep 19;45(16):9388-9397. doi: 10.1093/nar/gkx563. |
Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100), an antisense oligonucleotide targeting influenza a M1/M2 translation
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Citation:
Br J Clin Pharmacol. 2017 Sep 20. doi: 10.1111/bcp.13405. [Epub ahead of print] Epub:
Yes Abstract:
AIMS: The aims of the present study were to assess the safety, tolerability and pharmacokinetics of radavirsen following single... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Beigel JH, Voell J, Muñoz P, Kumar P, Brooks KM, Zhang J, Iversen P, Heald A, Wong M, Davey RT. Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100), an antisense oligonucleotide targeting influenza a M1/M2 translation. Br J Clin Pharmacol. 2017 Sep 20. doi: 10.1111/bcp.13405. [Epub ahead of print]. |
The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development
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Citation:
Exp Neurol. 2017 Sep 16. pii: S0014-4886(17)30239-X. doi: 10.1016/j.expneurol.2017.09.009. [Epub ahead of print] Review Epub:
Yes Abstract:
Macrophage migration inhibitory factor (MIF) is a neurotrophic cytokine essential for inner ear hair cell (HC) development and... Delivery Method:
electroporation Organism or Cell Type:
zebrafish Citation Extract: Weber LJ, Marcy HK, Shen YC, Tomkovich SE, Brooks KM, Hilk KE, Barald KF. The role of jab1, a putative downstream effector of the neurotrophic cytokine macrophage migration inhibitory factor (MIF) in zebrafish inner ear hair cell development. Exp Neurol. 2017 Sep 16. pii: S0014-4886(17)30239-X. doi: 10.1016/j.expneurol.2017.09.009. [Epub ahead of print] Review. |
Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin
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Citation:
Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print] Epub:
Yes Abstract:
Germ-layer formation during gastrulation is both a fundamental step of development and a paradigm for tissue formation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Giger FA, David NB. Endodermal germ-layer formation through active actin-driven migration triggered by N-cadherin. Proc Natl Acad Sci U S A. 2017 Sep 5. pii: 201708116. doi: 10.1073/pnas.1708116114. [Epub ahead of print]. |
Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly
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Citation:
Int J Biol Sci. 2017 Sep 2;13(8):1051-1066. doi: 10.7150/ijbs.19203. eCollection 2017 Epub:
Not Epub Abstract:
During embryonic gastrulation, coordinated cell movements occur to bring cells to their correct position. Among them, epiboly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun Q, Liu X, Gong B, Wu D, Meng A, Jia S. Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly. Int J Biol Sci. 2017 Sep 2;13(8):1051-1066. doi: 10.7150/ijbs.19203. eCollection 2017. |
Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing
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Citation:
Proc Natl Acad Sci U S A. 2017 Aug 30. pii: 201711158. doi: 10.1073/pnas.1711158114. [Epub ahead of print] Epub:
Yes Abstract:
Posttranslational histone modifications play important roles in regulating chromatin-based nuclear processes. Histone H2AK119... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Z, Jones AE, Wu W, Kim J, Kang Y, Bi X, Gu Y, Popov IK, Renfrow MB, Vassylyeva MN, Vassylyev DG, Giles KE, Chen D, Kumar A, Fan Y, Tong Y, Liu CF, An W, Chang C, Luo J, Chow LT, Wang H. Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing. Proc Natl Acad Sci U S A. 2017 Aug 30. pii: 201711158. doi: 10.1073/pnas.1711158114. [Epub ahead of print]. |
Cavin-2 regulates the activity and stability of endothelial nitric oxide synthase (eNOS) in angiogenesis
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Citation:
J Biol Chem. 2017 Sep 14. pii: jbc.M117.794743. doi: 10.1074/jbc.M117.794743. [Epub ahead of print] Epub:
Yes Abstract:
Angiogenesis is a highly regulated process for formation of new blood vessels from pre-existing ones. Angiogenesis is... Organism or Cell Type:
zebrafish Citation Extract: Boopathy GTK, Kulkarni M, Ho SY, Boey A, Chua EWM, Barathi VA, Carney TJ, Wang X, Hong W. Cavin-2 regulates the activity and stability of endothelial nitric oxide synthase (eNOS) in angiogenesis. J Biol Chem. 2017 Sep 14. pii: jbc.M117.794743. doi: 10.1074/jbc.M117.794743. [Epub ahead of print]. |