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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Homozygous EEF1A2 mutation causes dilated cardiomyopathy, failure to thrive, global developmental delay, epilepsy and early death
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Citation:
Hum Mol Genet. 2017 Sep 15;26(18):3545-3552. doi: 10.1093/hmg/ddx239 Epub:
Not Epub Abstract:
Eukaryotic elongation factor 1A (EEF1A), is encoded by two distinct isoforms, EEF1A1 and EEF1A2; whereas EEF1A1 is expressed... Organism or Cell Type:
zebrafish Citation Extract: Cao S, Smith LL, Padilla-Lopez SR, Guida BS, Blume E, Shi J, Morton SU, Brownstein CA, Beggs AH, Kruer MC, Agrawal PB. Homozygous EEF1A2 mutation causes dilated cardiomyopathy, failure to thrive, global developmental delay, epilepsy and early death. Hum Mol Genet. 2017 Sep 15;26(18):3545-3552. doi: 10.1093/hmg/ddx239. |
Quaking RNA-Binding Proteins Control Early Myofibril Formation by Modulating Tropomyosin
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Citation:
Dev Cell. 2017 Aug 28. pii: S1534-5807(17)30632-9. doi: 10.1016/j.devcel.2017.08.004. [Epub ahead of print] Epub:
Yes Abstract:
Skeletal muscle contraction is mediated by myofibrils, complex multi-molecular scaffolds structured into repeated units, the... Organism or Cell Type:
zebrafish Citation Extract: Bonnet A, Lambert G, Ernest S, Dutrieux FX, Coulpier F, Lemoine S, Lobbardi R, Rosa FM. Quaking RNA-Binding Proteins Control Early Myofibril Formation by Modulating Tropomyosin. Dev Cell. 2017 Aug 28. pii: S1534-5807(17)30632-9. doi: 10.1016/j.devcel.2017.08.004. [Epub ahead of print]. |
Engrailed controls epaxial-hypaxial muscle innervation and the establishment of vertebrate three-dimensional mobility
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Citation:
Dev Biol. 2017 Aug 12. pii: S0012-1606(17)30416-5. doi: 10.1016/j.ydbio.2017.08.011. [Epub ahead of print] Epub:
Yes Abstract:
Chordates are characterised by contractile muscle on either side of the body that promotes movement by side-to-side undulation... Organism or Cell Type:
zebrafish Citation Extract: Ahmed MU, Maurya AK, Cheng L, Jorge EC, Schubert FR, Maire P, Basson MA, Ingham PW, Dietrich S. Engrailed controls epaxial-hypaxial muscle innervation and the establishment of vertebrate three-dimensional mobility. Dev Biol. 2017 Aug 12. pii: S0012-1606(17)30416-5. doi: 10.1016/j.ydbio.2017.08.011. [Epub ahead of print]. |
A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish
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Citation:
Dev Biol. 2017 Jul 28. pii: S0012-1606(17)30373-1. doi: 10.1016/j.ydbio.2017.07.017. [Epub ahead of print] Epub:
Yes Abstract:
The casper strain of zebrafish is widely used in studies ranging from cancer to neuroscience. casper offers the advantage of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: D'Agati G, Beltre R, Sessa A, Burger A, Zhou Y, Mosimann C, White RM. A defect in the mitochondrial protein Mpv17 underlies the transparent casper zebrafish. Dev Biol. 2017 Jul 28. pii: S0012-1606(17)30373-1. doi: 10.1016/j.ydbio.2017.07.017. [Epub ahead of print]. |
Calaxin establishes basal body orientation and coordinates movement of monocilia in sea urchin embryos
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Citation:
Sci Rep. 2017 Sep 7;7(1):10751. doi: 10.1038/s41598-017-10822-z Epub:
Not Epub Abstract:
Through their coordinated alignment and beating, motile cilia generate directional fluid flow and organismal movement. While... Delivery Method:
microinjection Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Mizuno K, Shiba K, Yaguchi J, Shibata D, Yaguchi S, Prulière G, Chenevert J, Inaba K. Calaxin establishes basal body orientation and coordinates movement of monocilia in sea urchin embryos. Sci Rep. 2017 Sep 7;7(1):10751. doi: 10.1038/s41598-017-10822-z. |
Epigenetic regulation of left-right asymmetry by DNA methylation
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Citation:
EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201796580 Epub:
Yes Abstract:
DNA methylation is a major epigenetic modification; however, the precise role of DNA methylation in vertebrate development is... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Wang L, Liu Z, Lin H, Ma D, Tao Q, Liu F. Epigenetic regulation of left-right asymmetry by DNA methylation. EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201796580. |
PaxA, but not PaxC, is required for cnidocyte development in the sea anemone Nematostella vectensis
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Citation:
Evodevo. 2017 Sep 4;8:14. doi: 10.1186/s13227-017-0077-7. eCollection 2017 Epub:
Not Epub Abstract:
BACKGROUND: Pax genes are a family of conserved transcription factors that regulate many aspects of developmental morphogenesis... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Babonis LS, Martindale MQ. PaxA, but not PaxC, is required for cnidocyte development in the sea anemone Nematostella vectensis. Evodevo. 2017 Sep 4;8:14. doi: 10.1186/s13227-017-0077-7. eCollection 2017. |
Identification of a new adtrp1-tfpi regulatory axis for the specification of primitive myelopoiesis and definitive hematopoiesis
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Citation:
FASEB J. 2017 Sep 6. pii: fj.201700166RR. doi: 10.1096/fj.201700166RR. [Epub ahead of print] Epub:
Yes Abstract:
A genomic variant in the human ADTRP [androgen-dependent tissue factor (TF) pathway inhibitor (TFPI) regulating protein] gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang L, Wang X, Wang L, Yousaf M, Li J, Zuo M, Yang Z, Gou D, Bao B, Li L, Xiang N, Jia H, Xu C, Chen Q, Wang QK. Identification of a new adtrp1-tfpi regulatory axis for the specification of primitive myelopoiesis and definitive hematopoiesis. FASEB J. 2017 Sep 6. pii: fj.201700166RR. doi: 10.1096/fj.201700166RR. [Epub ahead of print]. |
m6A modulates haematopoietic stem and progenitor cell specification
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Citation:
Nature. 2017 Sep 6. doi: 10.1038/nature23883. [Epub ahead of print] Epub:
Yes Abstract:
N6-methyladenosine (m6A) has been identified as the most abundant modification on eukaryote messenger RNA (mRNA). Although the... Citation Extract: Zhang C, Chen Y, Sun B, Wang L, Yang Y, Ma D, Lv J, Heng J, Ding Y, Xue Y, Lu X, Xiao W, Yang YG, Liu F. m6A modulates haematopoietic stem and progenitor cell specification. Nature. 2017 Sep 6. doi: 10.1038/nature23883. [Epub ahead of print]. |
Autogenous Cross-Regulation Of Quaking mRNA Processing And Translation Balances Quaking Functions In Splicing And Translation
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Citation:
bioRxiv. 2017. doi:doi.org/10.1101/127936 Epub:
Not Epub Abstract:
Quaking protein isoforms arise from a single Quaking gene, and bind the same RNA motif to regulate splicing, translation, decay... Organism or Cell Type:
cell culture: mouse myoblasts Citation Extract: Fagg WS, Liu N, Fair JH, Shiue L, Katzmann S, Donohue J-P, Ares M. Autogenous Cross-Regulation Of Quaking mRNA Processing And Translation Balances Quaking Functions In Splicing And Translation. bioRxiv. 2017. doi:doi.org/10.1101/127936. |