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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Wnt signalling controls the response to mechanical loading during zebrafish joint development

Authors:
Brunt LH, Begg K, Kague E, Cross S, Hammond CL
Citation:
Development. 2017 Aug 1;144(15):2798-2809. doi: 10.1242/dev.153528. Epub 2017 Jul 6
Epub:
Not Epub
Abstract:
Joint morphogenesis requires mechanical activity during development. Loss of mechanical strain causes abnormal joint...
Link:
http://dev.biologists.org/content/144/15/2798
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brunt LH, Begg K, Kague E, Cross S, Hammond CL. Wnt signalling controls the response to mechanical loading during zebrafish joint development. Development. 2017 Aug 1;144(15):2798-2809. doi: 10.1242/dev.153528. Epub 2017 Jul 6.

Ikk2 regulates cytokinesis during vertebrate development

Authors:
Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V
Citation:
Sci Rep. 2017;7:8094. doi:10.1038/s41598-017-06904-7
Epub:
Not Epub
Abstract:
NFκB signaling has a pivotal role in regulation of development, innate immunity, and inflammation. Ikk2 is one of the two...
Link:
https://www.nature.com/articles/s41598-017-06904-7
Organism or Cell Type:
zebrafish
Citation Extract:
Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V. Ikk2 regulates cytokinesis during vertebrate development. Sci Rep. 2017;7:8094. doi:10.1038/s41598-017-06904-7.

A Functional Assay for Sick Sinus Syndrome Genetic Variants

Authors:
Jou CJ, Arrington CB, Barnett S, Shen J, Cho S, Sheng X, McCullagh PC, Bowles NE, Pribble CM, Saarel EV, Pilcher TA, Etheridge SP, Tristani-Firouzi M
Citation:
Cell Phys Biochem. 2017;42:2021-9. doi:10.1159/000479897
Epub:
Not Epub
Abstract:
Background/Aims: Congenital Sick Sinus Syndrome (SSS) is a disorder associated with sudden cardiac death due to severe...
Link:
https://www.karger.com/Article/FullText/479897
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jou CJ, Arrington CB, Barnett S, Shen J, Cho S, Sheng X, McCullagh PC, Bowles NE, Pribble CM, Saarel EV, Pilcher TA, Etheridge SP, Tristani-Firouzi M. A Functional Assay for Sick Sinus Syndrome Genetic Variants. Cell Phys Biochem. 2017;42:2021-9. doi:10.1159/000479897.

The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b

Authors:
Yuanyuan Xue Y, Lv J, Zhang C, Wang L, Ma D, Liu F
Citation:
Dev Cell. 2017;[Epub ahead of print] doi:10.1016/j.devcel.2017.07.012
Epub:
Not Epub
Abstract:
In mammals, hematopoietic stem and progenitor cells (HSPCs) rapidly expand in the fetal liver (FL), but the underlying...
Link:
http://www.cell.com/developmental-cell/abstract/S1534-5807(17)30554-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuanyuan Xue Y, Lv J, Zhang C, Wang L, Ma D, Liu F. The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b. Dev Cell. 2017;[Epub ahead of print] doi:10.1016/j.devcel.2017.07.012.

TNF signaling and macrophages govern fin regeneration in zebrafish larvae

Authors:
Nguyen-Chi M, Laplace-Builhé B, Travnickova J, Luz-Crawford P, Tejedor G, Lutfalla G, Kissa K, Jorgensen C, Djouad F
Citation:
Cell Death Dis. 2017 Aug 10;8(8):e2979. doi: 10.1038/cddis.2017.374
Epub:
Not Epub
Abstract:
Macrophages are essential for appendage regeneration after amputation in regenerative species. The molecular mechanisms through...
Link:
https://www.nature.com/cddis/journal/v8/n8/full/cddis2017374a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nguyen-Chi M, Laplace-Builhé B, Travnickova J, Luz-Crawford P, Tejedor G, Lutfalla G, Kissa K, Jorgensen C, Djouad F. TNF signaling and macrophages govern fin regeneration in zebrafish larvae. Cell Death Dis. 2017 Aug 10;8(8):e2979. doi: 10.1038/cddis.2017.374.

Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system

Authors:
Han Y, Xiong Y, Shi X, Wu J, Zhao Y, Jiang J
Citation:
PLoS Biol. 2017 Aug 4;15(8):e2002063. doi: 10.1371/journal.pbio.2002063. eCollection 2017 Aug
Epub:
Not Epub
Abstract:
Hedgehog (Hh) signaling in vertebrates depends on primary cilia. Upon stimulation, Hh pathway components, including Gli...
Link:
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2002063
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Han Y, Xiong Y, Shi X, Wu J, Zhao Y, Jiang J. Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system. PLoS Biol. 2017 Aug 4;15(8):e2002063. doi: 10.1371/journal.pbio.2002063. eCollection 2017 Aug.

CBFβ initiates the hematopoietic stem cell program without obligatory binding to RUNX

Authors:
Ciau-Uitz A, Pinheiro P, Kirmizitas A, Fernandez C, Patient R
Citation:
bioRxiv. 2017;[preprint] doi:10.1101/172957
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) emerge from hemogenic endothelium (HE) localised in the embryonic dorsal aorta (DA). Here we...
Link:
http://www.biorxiv.org/content/biorxiv/early/2017/08/05/172957.full.pdf
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ciau-Uitz A, Pinheiro P, Kirmizitas A, Fernandez C, Patient R. CBFβ initiates the hematopoietic stem cell program without obligatory binding to RUNX. bioRxiv. 2017;[preprint] doi:10.1101/172957.

Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes

Authors:
Dong X, Li J, He L, Gu C, Jia W, Yue Y, Li J, Zhang Q, Chu L, Zhao Q
Citation:
J Biol Chem. 2017 Aug 4;292(31):13045-13055. doi: 10.1074/jbc.M117.777094. Epub 2017 Jun 16
Epub:
Not Epub
Abstract:
Transcription factors play crucial roles in patterning posterior neuroectoderm. Previously, zinc finger transcription factor...
Link:
http://www.jbc.org/content/292/31/13045.short
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dong X, Li J, He L, Gu C, Jia W, Yue Y, Li J, Zhang Q, Chu L, Zhao Q. Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes. J Biol Chem. 2017 Aug 4;292(31):13045-13055. doi: 10.1074/jbc.M117.777094. Epub 2017 Jun 16.

hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus

Authors:
Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K
Citation:
Dev Biol. 2017 Aug 1. pii: S0012-1606(17)30032-5. doi: 10.1016/j.ydbio.2017.07.020. [Epub ahead of print]
Epub:
Yes
Abstract:
Development of the central nervous system requires orchestration of morphogenetic processes which drive elevation and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160617300325
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Prager A, Hagenlocher C, Ott T, Schambony A, Feistel K. hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus. Dev Biol. 2017 Aug 1. pii: S0012-1606(17)30032-5. doi: 10.1016/j.ydbio.2017.07.020. [Epub ahead of print].

Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality

Authors:
Kim JG, Bae SJ, Lee HS, Park JH, Kim KW
Citation:
PLoS One. 2017 Aug 3;12(8):e0182047. doi: 10.1371/journal.pone.0182047. eCollection 2017
Epub:
Not Epub
Abstract:
Left-right asymmetric organ development is critical to establish a proper body plan of vertebrates. In zebrafish, the Kupffer...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182047
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim JG, Bae SJ, Lee HS, Park JH, Kim KW. Claudin5a is required for proper inflation of Kupffer's vesicle lumen and organ laterality. PLoS One. 2017 Aug 3;12(8):e0182047. doi: 10.1371/journal.pone.0182047. eCollection 2017.

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