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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis

Authors:
Salamaga B, Prajsnar TK, Jareño-Martinez A, Willemse J, Bewley MA, Chau F, Ben Belkacem T, Meijer AH, Dockrell DH, Renshaw SA, Mesnage S
Citation:
PLoS Pathog. 2-17;13(7):e1006526. doi:10.1371/journal.ppat.1006526
Epub:
Not Epub
Abstract:
Enterococcus faecalis is an opportunistic pathogen frequently isolated in clinical settings. This organism is intrinsically...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Salamaga B, Prajsnar TK, Jareño-Martinez A, Willemse J, Bewley MA, Chau F, Ben Belkacem T, Meijer AH, Dockrell DH, Renshaw SA, Mesnage S. Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis. PLoS Pathog. 2-17;13(7):e1006526. doi:10.1371/journal.ppat.1006526.

Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish

Authors:
Wehner D, Tsarouchas TM, Michael A, Haase C, Weidinger G, Reimer MM, Becker T, Becker CG
Citation:
Nat Comm. 2017;8:126. doi:10.1038/s41467-017-00143-0
Epub:
Not Epub
Abstract:
The inhibitory extracellular matrix in a spinal lesion site is a major impediment to axonal regeneration in mammals. In...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Wehner D, Tsarouchas TM, Michael A, Haase C, Weidinger G, Reimer MM, Becker T, Becker CG. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish. Nat Comm. 2017;8:126. doi:10.1038/s41467-017-00143-0.

An Actomyosin-Arf-GEF Negative Feedback Loop for Tissue Elongation under Stress

Authors:
West JJ, Zulueta-Coarasa T, Maier JA, Lee DM, Bruce AEE, Fernandez-Gonzalez R, Harris TJC
Citation:
Curr Biol. 2017;{Epub ahead of print] doi:10.1016/j.cub.2017.06.038
Epub:
Yes
Abstract:
In response to a pulling force, a material can elongate, hold fast, or fracture. During animal development, multi-cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
West JJ, Zulueta-Coarasa T, Maier JA, Lee DM, Bruce AEE, Fernandez-Gonzalez R, Harris TJC. An Actomyosin-Arf-GEF Negative Feedback Loop for Tissue Elongation under Stress. Curr Biol. 2017;{Epub ahead of print] doi:10.1016/j.cub.2017.06.038.

Protein kinase Cϵ stabilizes β-catenin and regulates its subcellular localization in podocytes

Authors:
Duong M, Yu X, Teng B, Schroder P, Haller H, Eschenburg S, Schiffer M
Citation:
J Biol Chem. 2017;292:12100-10 doi:10.1074/jbc.M117.775700
Epub:
Not Epub
Abstract:
Kidney disease has been linked to dysregulated signaling via PKC in kidney cells such as podocytes. PKCα is a conventional...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Duong M, Yu X, Teng B, Schroder P, Haller H, Eschenburg S, Schiffer M. Protein kinase Cϵ stabilizes β-catenin and regulates its subcellular localization in podocytes. J Biol Chem. 2017;292:12100-10 doi:10.1074/jbc.M117.775700.

Number of inadvertent RNA targets for morpholino knockdown in Danio rerio is largely underestimated: evidence from the study of Ser/Arg-rich splicing factors

Authors:
Joris M, Schloesser M, Baurain D, Hanikenne M, Muller M, Motte P
Citation:
Nucleic Acids Res. 2017;[Epub ahead of print] doi:10.1093/nar/gkx638
Epub:
Yes
Abstract:
Although the involvement of Ser/Arg-rich (SR) proteins in RNA metabolism is well documented, their role in vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Joris M, Schloesser M, Baurain D, Hanikenne M, Muller M, Motte P. Number of inadvertent RNA targets for morpholino knockdown in Danio rerio is largely underestimated: evidence from the study of Ser/Arg-rich splicing factors. Nucleic Acids Res. 2017;[Epub ahead of print] doi:10.1093/nar/gkx638.

SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development

Authors:
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M
Citation:
Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15.
Epub:
Not Epub
Abstract:
Arterial specification and differentiation are influenced by a number of regulatory pathways. While it is known that the Vegfa-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M. SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15..

Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues

Authors:
Demy DL, Tauzin M, Lancino M, le Cabec V, Redd M, Murayama E, Maridonneau-Parini I, Trede N, Herbomel P
Citation:
J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.203471
Epub:
Yes
Abstract:
Macrophages infiltrate and establish in developing organs from an early stage, often before these have become vascularised....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Demy DL, Tauzin M, Lancino M, le Cabec V, Redd M, Murayama E, Maridonneau-Parini I, Trede N, Herbomel P. Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues. J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.203471.

Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells

Authors:
Egesipe AL, Blondel S, Cicero AL, Jaskowiak AL, Navarro C, Sandre-Giovannoli A, Levy N, Peschanski M, Nissan X
Citation:
NPJ Aging Mech Dis. 2016 Nov 10;2:16026. doi: 10.1038/npjamd.2016.26. eCollection 2016
Epub:
Not Epub
Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder that causes systemic accelerated aging in children. This...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HGPS MSCs
Citation Extract:
Egesipe AL, Blondel S, Cicero AL, Jaskowiak AL, Navarro C, Sandre-Giovannoli A, Levy N, Peschanski M, Nissan X. Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells. NPJ Aging Mech Dis. 2016 Nov 10;2:16026. doi: 10.1038/npjamd.2016.26. eCollection 2016.

Dexamethasone-induced hepatomegaly and steatosis in larval zebrafish

Authors:
Yin G, Cao L, Du J, Jia R, Kitazawa T, Kubota A, Teraoka H
Citation:
J Toxicol Sci. 2017;42(4):455-459. doi: 10.2131/jts.42.455
Epub:
Not Epub
Abstract:
Fish hepatobiliary syndrome, characterized by hepatomegaly and fatty liver, has been frequently reported in many cultured fish...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yin G, Cao L, Du J, Jia R, Kitazawa T, Kubota A, Teraoka H. Dexamethasone-induced hepatomegaly and steatosis in larval zebrafish. J Toxicol Sci. 2017;42(4):455-459. doi: 10.2131/jts.42.455.

Klf8 regulates left-right asymmetric patterning through modulation of Kupffer's vesicle morphogenesis and spaw expression

Authors:
Lin CY, Tsai MY, Liu YH, Lu YF, Chen YC, Lai YR, Liao HC, Lien HW, Yang CH, Huang CJ, Hwang SL
Citation:
J Biomed Sci. 2017 Jul 17;24(1):45. doi: 10.1186/s12929-017-0351-y
Epub:
Not Epub
Abstract:
BACKGROUND: Although vertebrates are bilaterally symmetric organisms, their internal organs are distributed asymmetrically...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CY, Tsai MY, Liu YH, Lu YF, Chen YC, Lai YR, Liao HC, Lien HW, Yang CH, Huang CJ, Hwang SL. Klf8 regulates left-right asymmetric patterning through modulation of Kupffer's vesicle morphogenesis and spaw expression. J Biomed Sci. 2017 Jul 17;24(1):45. doi: 10.1186/s12929-017-0351-y.

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