You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation

Authors:
Gallagher TL, Tietz KT, Morrow ZT, McCammon JM, Goldrich ML, Derr NL, Amacher SL
Citation:
Dev Biol. 2017 Jun 22. pii: S0012-1606(17)30265-8. doi: 10.1016/j.ydbio.2017.06.024. [Epub ahead of print]
Epub:
Yes
Abstract:
Vertebrate segmentation is controlled by the segmentation clock, a molecular oscillator that regulates gene expression and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160617302658
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gallagher TL, Tietz KT, Morrow ZT, McCammon JM, Goldrich ML, Derr NL, Amacher SL. Pnrc2 regulates 3'UTR-mediated decay of segmentation clock-associated transcripts during zebrafish segmentation. Dev Biol. 2017 Jun 22. pii: S0012-1606(17)30265-8. doi: 10.1016/j.ydbio.2017.06.024. [Epub ahead of print].

Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation

Authors:
Pünzeler S, Link S, Wagner G, Keilhauer EC, Kronbeck N, Spitzer RM, Leidescher S, Markaki Y, Mentele E, Regnard C, Schneider K, Takahashi D, Kusakabe M, Vardabasso C, Zink LM, Straub T, Bernstein E, Harata M, Leonhardt H, Mann M, Rupp RA, Hake SB
Citation:
EMBO J. 2017 Jun 23. pii: e201695757. doi: 10.15252/embj.201695757. [Epub ahead of print]
Epub:
Yes
Abstract:
Replacement of canonical histones with specialized histone variants promotes altering of chromatin structure and function. The...
Link:
http://emboj.embopress.org/content/early/2017/06/23/embj.201695757
Organism or Cell Type:
Xenopus
Citation Extract:
Pünzeler S, Link S, Wagner G, Keilhauer EC, Kronbeck N, Spitzer RM, Leidescher S, Markaki Y, Mentele E, Regnard C, Schneider K, Takahashi D, Kusakabe M, Vardabasso C, Zink LM, Straub T, Bernstein E, Harata M, Leonhardt H, Mann M, Rupp RA, Hake SB. Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation. EMBO J. 2017 Jun 23. pii: e201695757. doi: 10.15252/embj.201695757. [Epub ahead of print].

RAPGEF5 regulates nuclear translocation of β-catenin

Authors:
Griffin JN, del Viso F, Duncan AR, Robson A, Kulkarni S, Liu KJ, Khokha MK
Citation:
bioRXiv. 2017. doi:10.1101/152892
Epub:
Not Epub
Abstract:
Canonical Wnt signaling coordinates many critical aspects of embryonic development, while dysregulated Wnt signaling...
Link:
http://www.biorxiv.org/content/early/2017/06/20/152892
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Griffin JN, del Viso F, Duncan AR, Robson A, Kulkarni S, Liu KJ, Khokha MK. RAPGEF5 regulates nuclear translocation of β-catenin. bioRXiv. 2017. doi:10.1101/152892.

Melatonin protects against maternal obesity-associated oxidative stress and meiotic defects in oocytes via the SIRT3-SOD2 dependent pathway

Authors:
Han L, Wang H, Li L, Li X, Ge J, Reiter RJ, Wang Q
Citation:
J Pineal Res. 2017 Jun 28. doi: 10.1111/jpi.12431. [Epub ahead of print]
Epub:
Yes
Abstract:
Maternal obesity in humans is associated with poor outcomes across the reproductive spectrum. Emerging evidence indicates that...
Link:
http://onlinelibrary.wiley.com/doi/10.1111/jpi.12431/abstract
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Han L, Wang H, Li L, Li X, Ge J, Reiter RJ, Wang Q . Melatonin protects against maternal obesity-associated oxidative stress and meiotic defects in oocytes via the SIRT3-SOD2 dependent pathway. J Pineal Res. 2017 Jun 28. doi: 10.1111/jpi.12431. [Epub ahead of print].

In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression

Authors:
Garcia GR, Goodale BC, Wiley MW, La Du JK, Hendrix DA, Tanguay RL
Citation:
Mol Pharmacol. 2017 Jun; 91(6): 609-19. Published online 2017 Jun. doi: 10.1124/mol.117.108233
Epub:
Not Epub
Abstract:
Xenobiotic activation of the aryl hydrocarbon receptor (AHR) by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) prevents the proper...
Link:
http://molpharm.aspetjournals.org/content/91/6/609
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garcia GR, Goodale BC, Wiley MW, La Du JK, Hendrix DA, Tanguay RL. In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression. Mol Pharmacol. 2017 Jun; 91(6): 609-19. Published online 2017 Jun. doi: 10.1124/mol.117.108233.

Contrasting the Role of xCT and GLT-1 Upregulation in the Ability of Ceftriaxone to Attenuate the Cue-Induced Reinstatement of Cocaine Seeking and Normalize AMPA Receptor Subunit Expression

Authors:
LaCrosse AL, O'Donovan SM, Sepulveda-Orengo MT, McCullumsmith RE, Reissner KJ, Schwendt M, Knackstedt LA
Citation:
J Neurosci. 2017 Jun 14;37(24):5809-5821. doi: 10.1523/JNEUROSCI.3717-16.2017. Epub 2017 May 11
Epub:
Not Epub
Abstract:
Long-term treatment with ceftriaxone attenuates the reinstatement of cocaine seeking while increasing the function of the...
Link:
http://www.jneurosci.org/content/37/24/5809
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
LaCrosse AL, O'Donovan SM, Sepulveda-Orengo MT, McCullumsmith RE, Reissner KJ, Schwendt M, Knackstedt LA. Contrasting the Role of xCT and GLT-1 Upregulation in the Ability of Ceftriaxone to Attenuate the Cue-Induced Reinstatement of Cocaine Seeking and Normalize AMPA Receptor Subunit Expression. J Neurosci. 2017 Jun 14;37(24):5809-5821. doi: 10.1523/JNEUROSCI.3717-16.2017. Epub 2017 May 11.

Electrostatic Cycling of Hybridization Using Nonionic DNA Mimics

Authors:
Ruffin S, Hung IA, Koniges UM, Levicky R
Citation:
ACS Sens. 2017 Jul 28;2(7):892-896. doi: 10.1021/acssensors.7b00100. Epub 2017 Jun 20.
Epub:
Not Epub
Abstract:
This study demonstrates efficient electrostatic control of surface hybridization through use of morpholinos, a charge-neutral...
Link:
http://pubs.acs.org/doi/abs/10.1021/acssensors.7b00100?journalCode=ascefj
Citation Extract:
Ruffin S, Hung IA, Koniges UM, Levicky R. Electrostatic Cycling of Hybridization Using Nonionic DNA Mimics. ACS Sens. 2017 Jul 28;2(7):892-896. doi: 10.1021/acssensors.7b00100. Epub 2017 Jun 20..

Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos

Authors:
Wu Y, Lou QY, Ge F, Xiong Q
Citation:
Sci Rep. 2017 Jun 22;7(1):4022. doi: 10.1038/s41598-017-04166-x
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are noncoding RNAs which control gene expression by the suppression of translation or the degradation of...
Link:
https://www.nature.com/articles/s41598-017-04166-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Y, Lou QY, Ge F, Xiong Q. Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos. Sci Rep. 2017 Jun 22;7(1):4022. doi: 10.1038/s41598-017-04166-x.

A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features

Authors:
Marin-Valencia I, Novarino G, Johansen A, Rosti B, Issa MY, Musaev D, Bhat G, Scott E, Silhavy JL, Stanley V, Rosti RO, Gleeson JW, Imam FB, Zaki MS, Gleeson JG
Citation:
J Med Genet. 2017 Jun 16. pii: jmedgenet-2017-104627. doi: 10.1136/jmedgenet-2017-104627. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Transport protein particle (TRAPP) is a multisubunit complex that regulates membrane trafficking through the Golgi...
Link:
http://jmg.bmj.com/content/early/2017/06/16/jmedgenet-2017-104627.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marin-Valencia I, Novarino G, Johansen A, Rosti B, Issa MY, Musaev D, Bhat G, Scott E, Silhavy JL, Stanley V, Rosti RO, Gleeson JW, Imam FB, Zaki MS, Gleeson JG. A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features. J Med Genet. 2017 Jun 16. pii: jmedgenet-2017-104627. doi: 10.1136/jmedgenet-2017-104627. [Epub ahead of print].

miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development

Authors:
Kara N, Wei C, Commanday AC, Patton JG
Citation:
Dev Biol. 2017 Jun 16. pii: S0012-1606(16)30850-8. doi: 10.1016/j.ydbio.2017.06.013. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cranial neural crest cells are a multipotent cell population that generate all the elements of the pharyngeal cartilage with...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616308508
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kara N, Wei C, Commanday AC, Patton JG. miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development. Dev Biol. 2017 Jun 16. pii: S0012-1606(16)30850-8. doi: 10.1016/j.ydbio.2017.06.013. [Epub ahead of print].

Pages