You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease

Authors:
Haskell GT, Jensen BC, Samsa LA, Marchuk D, Huang W, Skrzynia C, Tilley C, Seifert BA, Rivera-Muñoz EA, Koller B, Wilhelmsen KC, Liu J, Alhosaini H, Weck KE, Evans JP, Berg JS
Citation:
Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001443. doi: 10.1161/CIRCGENETICS.116.001443
Epub:
Yes
Abstract:
BACKGROUND: The genetic variation underlying many heritable forms of cardiovascular disease is incompletely understood, even in...
Link:
http://circgenetics.ahajournals.org/content/10/3/e001443.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Haskell GT, Jensen BC, Samsa LA, Marchuk D, Huang W, Skrzynia C, Tilley C, Seifert BA, Rivera-Muñoz EA, Koller B, Wilhelmsen KC, Liu J, Alhosaini H, Weck KE, Evans JP, Berg JS. Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease. Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001443. doi: 10.1161/CIRCGENETICS.116.001443.

Targeted gene knockdown validates the essential role of lactate dehydrogenase in Cryptosporidium parvum

Authors:
Witola WH, Zhang X, Kim CY
Citation:
Int J Parasitol. 2017 Jun 9. pii: S0020-7519(17)30166-2. doi: 10.1016/j.ijpara.2017.05.002. [Epub ahead of print]
Epub:
Yes
Abstract:
Cryptosporidium parvum is a zoonotic protozoan that can cause a life-threatening gastrointestinal syndrome in children and in...
Link:
http://www.sciencedirect.com/science/article/pii/S0020751917301662
Delivery Method:
Vivo-Morpholino, Endo-Porter
Organism or Cell Type:
Cryptosporidium parvum
Citation Extract:
Witola WH, Zhang X, Kim CY. Targeted gene knockdown validates the essential role of lactate dehydrogenase in Cryptosporidium parvum. Int J Parasitol. 2017 Jun 9. pii: S0020-7519(17)30166-2. doi: 10.1016/j.ijpara.2017.05.002. [Epub ahead of print].

Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2-/- mice

Authors:
Hall C, Ehrlich L, Meng F, Invernizzi P, Bernuzzi F, Lairmore TC, Alpini G, Glaser S
Citation:
J Surg Res. 2017 May 11. pii: S0022-4804(17)30273-1. doi: 10.1016/j.jss.2017.05.020. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Liver transplantation remains the primary treatment for primary sclerosing cholangitis (PSC). Mdr2-/- mice provide...
Link:
http://www.journalofsurgicalresearch.com/article/S0022-4804(17)30273-1/fulltext
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice Mdr2-/-
Citation Extract:
Hall C, Ehrlich L, Meng F, Invernizzi P, Bernuzzi F, Lairmore TC, Alpini G, Glaser S. Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2-/- mice. J Surg Res. 2017 May 11. pii: S0022-4804(17)30273-1. doi: 10.1016/j.jss.2017.05.020. [Epub ahead of print].

Cationic Cytosine Morpholino-Based Transporters: Synthesis and Regulation of Intracellular Localization

Authors:
Nandi B, Khatra H, Khan PP, Bhadra J, Pattanayak S, Sinha S.
Citation:
ChemistrySelect. 2017;2:5059-67 doi:10.1002/slct.201700238
Epub:
Not Epub
Abstract:
Cationic guanidinium and phosphonium functionalized cytosine morpholino tetramer (G3) and trimer (P3) have been reported for...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/slct.201700238/abstract
Delivery Method:
modified cationic cytosine moieties
Organism or Cell Type:
zebrafish
Citation Extract:
Nandi B, Khatra H, Khan PP, Bhadra J, Pattanayak S, Sinha S.. Cationic Cytosine Morpholino-Based Transporters: Synthesis and Regulation of Intracellular Localization. ChemistrySelect. 2017;2:5059-67 doi:10.1002/slct.201700238.

Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

Authors:
Drew K, Lee C, Huizar RL, Tu F, Borgeson B, McWhite CD, Ma Y, Wallingford JB, Marcotte EM
Citation:
Mol Syst Biol. 2017 Jun 8;13(6):932. doi: 10.15252/msb.20167490
Epub:
Yes
Abstract:
Macromolecular protein complexes carry out many of the essential functions of cells, and many genetic diseases arise from...
Link:
http://msb.embopress.org/content/13/6/932
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Drew K, Lee C, Huizar RL, Tu F, Borgeson B, McWhite CD, Ma Y, Wallingford JB, Marcotte EM. Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes. Mol Syst Biol. 2017 Jun 8;13(6):932. doi: 10.15252/msb.20167490.

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis

Authors:
Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X
Citation:
Nat Commun. 2017 Jun 7;8:15279. doi: 10.1038/ncomms15279
Epub:
Yes
Abstract:
The apical-basal (AB) polarity and planar cell polarity (PCP) provide an animal cell population with different phenotypes...
Link:
https://www.nature.com/articles/ncomms15279
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish and Xenopus laevis
Citation Extract:
Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X. The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis. Nat Commun. 2017 Jun 7;8:15279. doi: 10.1038/ncomms15279.

Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart

Authors:
Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS
Citation:
Cell Death Dis. 2017 Jun 8;8(6):e2861. doi: 10.1038/cddis.2017.185
Epub:
Not Epub
Abstract:
Congenital heart defects contribute to embryonic or neonatal lethality but due to the complexity of cardiac development, the...
Link:
https://www.nature.com/cddis/journal/v8/n6/full/cddis2017185a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS. Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart. Cell Death Dis. 2017 Jun 8;8(6):e2861. doi: 10.1038/cddis.2017.185.

Bsx in Neuroendocrine and Pineal Complex Development

Authors:
Schredelseker S, Driever W
Citation:
Mech Dev. 2017;145(Suppl):S124(PS4.31). doi:doi.org/10.1016/j.mod.2017.04.338
Epub:
Not Epub
Abstract:
No abstract available
Link:
http://www.sciencedirect.com/science/article/pii/S0925477317304215
Organism or Cell Type:
zebrafish
Citation Extract:
Schredelseker S, Driever W. Bsx in Neuroendocrine and Pineal Complex Development. Mech Dev. 2017;145(Suppl):S124(PS4.31). doi:doi.org/10.1016/j.mod.2017.04.338.

Glycogen reduction in myotubes of late-onset Pompe disease patients using antisense technology

Authors:
Goina E, Peruzzo P, Bembi B, Dardis A, Buratti E
Citation:
Mol Ther. 2017;[Epub ahead of print] doi:10.1016/j.ymthe.2017.05.019
Epub:
Yes
Abstract:
Glycogen storage disease type II (GSDII) is a lysosomal disorder caused by the deficient activity of acid alpha-glucosidase (...
Link:
http://www.cell.com/molecular-therapy-family/molecular-therapy/abstract/S1525-0016(17)30253-8
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HeLa, primary myoblasts differentiated to myotubes
Citation Extract:
Goina E, Peruzzo P, Bembi B, Dardis A, Buratti E. Glycogen reduction in myotubes of late-onset Pompe disease patients using antisense technology. Mol Ther. 2017;[Epub ahead of print] doi:10.1016/j.ymthe.2017.05.019.

Hif-1 stabilization in zebrafish neural crest

Authors:
Espina J, Marchant C, Reys A
Citation:
Mech Dev. 2017;145(Suppl):S129-30(PS4.50). doi:10.1016/j.mod.2017.04.357
Epub:
Not Epub
Abstract:
No abstract available
Link:
http://www.sciencedirect.com/science/article/pii/S0925477317304409
Organism or Cell Type:
zebrafish
Citation Extract:
Espina J, Marchant C, Reys A. Hif-1 stabilization in zebrafish neural crest. Mech Dev. 2017;145(Suppl):S129-30(PS4.50). doi:10.1016/j.mod.2017.04.357.

Pages