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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex

Authors:
Zhang P, Bai Y, Lu L, Li Y, Duan C
Citation:
Elife. 2016 Jan 14;5. pii: e08996. doi: 10.7554/eLife.08996
Epub:
Not Epub
Abstract:
Hypoxia-inducible factors (HIFs), while best known for their roles in the hypoxic response, have oxygen-independent roles in...
Link:
https://elifesciences.org/articles/08996
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang P, Bai Y, Lu L, Li Y, Duan C. An oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex. Elife. 2016 Jan 14;5. pii: e08996. doi: 10.7554/eLife.08996.

SPOP mutation leads to genomic instability in prostate cancer

Authors:
Boysen G, Barbieri CE, Prandi D, Blattner M, Chae SS, Dahija A, Nataraj S, Huang D, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Liu D, Zhou P, Sboner A, de Bono JS, Demichelis F, Houvras Y, Rubin MA
Citation:
Elife. 2015 Sep 16;4. pii: e09207. doi: 10.7554/eLife.09207
Epub:
Not Epub
Abstract:
Genomic instability is a fundamental feature of human cancer often resulting from impaired genome maintenance. In prostate...
Link:
https://elifesciences.org/articles/09207
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boysen G, Barbieri CE, Prandi D, Blattner M, Chae SS, Dahija A, Nataraj S, Huang D, Marotz C, Xu L, Huang J, Lecca P, Chhangawala S, Liu D, Zhou P, Sboner A, de Bono JS, Demichelis F, Houvras Y, Rubin MA. SPOP mutation leads to genomic instability in prostate cancer. Elife. 2015 Sep 16;4. pii: e09207. doi: 10.7554/eLife.09207.

Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit

Authors:
Hatzold J, Beleggia F, Herzig H, Altmüller J, Nürnberg P, Bloch W, Wollnik B, Hammerschmidt M
Citation:
Elife. 2016 May 30;5. pii: e14277. doi: 10.7554/eLife.14277
Epub:
Not Epub
Abstract:
The molecular pathways underlying tumor suppression are incompletely understood. Here, we identify cooperative non-cell-...
Link:
https://elifesciences.org/articles/14277v3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hatzold J, Beleggia F, Herzig H, Altmüller J, Nürnberg P, Bloch W, Wollnik B, Hammerschmidt M. Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit. Elife. 2016 May 30;5. pii: e14277. doi: 10.7554/eLife.14277.

IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva

Authors:
Buckley KM, Ho ECH, Hibino T, Schrankel CS, Schuh NW, Wang G, Rast JP
Citation:
Elife. 2017 Apr 27;6. pii: e23481. doi: 10.7554/eLife.23481
Epub:
Not Epub
Abstract:
IL17 cytokines are central mediators of mammalian immunity. In vertebrates, these factors derive from diverse cellular sources...
Link:
https://elifesciences.org/articles/23481
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Buckley KM, Ho ECH, Hibino T, Schrankel CS, Schuh NW, Wang G, Rast JP. IL17 factors are early regulators in the gut epithelium during inflammatory response to Vibrio in the sea urchin larva. Elife. 2017 Apr 27;6. pii: e23481. doi: 10.7554/eLife.23481.

The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo

Authors:
Sant KE, Hansen JM, Williams LM, Tran NL, Goldstone JV, Stegeman JJ, Hahn ME, Timme-Laragy A
Citation:
Redox Biol. 2017 May 30;13:207-218. doi: 10.1016/j.redox.2017.05.023. [Epub ahead of print]
Epub:
Yes
Abstract:
Redox signaling is important for embryogenesis, guiding pathways that govern processes crucial for embryo patterning, including...
Link:
http://www.sciencedirect.com/science/article/pii/S2213231717302409
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sant KE, Hansen JM, Williams LM, Tran NL, Goldstone JV, Stegeman JJ, Hahn ME, Timme-Laragy A. The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo. Redox Biol. 2017 May 30;13:207-218. doi: 10.1016/j.redox.2017.05.023. [Epub ahead of print].

The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development

Authors:
Kroeger PT Jr, Drummond BE, Miceli R, McKernan M, Gerlach GF, Marra AN, Fox A, McCampbell KK, Leshchiner I, Rodriguez-Mari A, BreMiller R, Thummel R, Davidson AJ, Postlethwait J, Goessling W, Wingert RA
Citation:
Dev Biol. 2017 Jun 1. pii: S0012-1606(16)30468-7. doi: 10.1016/j.ydbio.2017.05.025. [Epub ahead of print]
Epub:
Yes
Abstract:
The zebrafish kidney is conserved with other vertebrates, making it an excellent genetic model to study renal development. The...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160616304687
Organism or Cell Type:
zebrafish
Citation Extract:
Kroeger PT Jr, Drummond BE, Miceli R, McKernan M, Gerlach GF, Marra AN, Fox A, McCampbell KK, Leshchiner I, Rodriguez-Mari A, BreMiller R, Thummel R, Davidson AJ, Postlethwait J, Goessling W, Wingert RA. The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development. Dev Biol. 2017 Jun 1. pii: S0012-1606(16)30468-7. doi: 10.1016/j.ydbio.2017.05.025. [Epub ahead of print].

Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a

Authors:
Gorsuch RA, Lahne M, Yarka CE, Petravick ME, Li J, Hyde DR
Citation:
Exp Eye Res. 2017 May 31. pii: S0014-4835(16)30265-2. doi: 10.1016/j.exer.2017.05.012. [Epub ahead of print]
Epub:
Yes
Abstract:
Sox2 is a well-established neuronal stem cell-associated transcription factor that regulates neural development and adult...
Link:
http://www.sciencedirect.com/science/article/pii/S0014483516302652
Organism or Cell Type:
zebrafish
Citation Extract:
Gorsuch RA, Lahne M, Yarka CE, Petravick ME, Li J, Hyde DR. Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a. Exp Eye Res. 2017 May 31. pii: S0014-4835(16)30265-2. doi: 10.1016/j.exer.2017.05.012. [Epub ahead of print].

Complement component C3aR constitutes a novel regulator for chick eye morphogenesis

Authors:
Grajales-Esquivel E, Luz-Madrigal A, Bierly J, Haynes T, Reis ES, Han Z, Gutierrez C, McKinney Z, Tzekou A, Lambris JD, Tsonis PA, Del Rio-Tsonis K
Citation:
Dev Biol. 2017 May 30. pii: S0012-1606(15)30062-2. doi: 10.1016/j.ydbio.2017.05.019. [Epub ahead of print]
Epub:
Yes
Abstract:
Complement components have been implicated in a wide variety of functions including neurogenesis, proliferation, cell migration...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160615300622
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Grajales-Esquivel E, Luz-Madrigal A, Bierly J, Haynes T, Reis ES, Han Z, Gutierrez C, McKinney Z, Tzekou A, Lambris JD, Tsonis PA, Del Rio-Tsonis K. Complement component C3aR constitutes a novel regulator for chick eye morphogenesis. Dev Biol. 2017 May 30. pii: S0012-1606(15)30062-2. doi: 10.1016/j.ydbio.2017.05.019. [Epub ahead of print].

Boron Nitride Nanotubes for Gene Silencing

Authors:
Şen Ö, Çobandede Z, Emanet M, Bayrak ÖF, Çulha M
Citation:
Biochim Biophys Acta. 2017 May 29. pii: S0304-4165(17)30178-2. doi: 10.1016/j.bbagen.2017.05.026. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Non-viral gene delivery is increasingly investigated as an alternative to viral vectors due to low toxicity and...
Link:
http://www.sciencedirect.com/science/article/pii/S0304416517301782
Delivery Method:
nanotubes
Organism or Cell Type:
cell culture: MDA-MB-231-luc2
Citation Extract:
Şen Ö, Çobandede Z, Emanet M, Bayrak ÖF, Çulha M. Boron Nitride Nanotubes for Gene Silencing. Biochim Biophys Acta. 2017 May 29. pii: S0304-4165(17)30178-2. doi: 10.1016/j.bbagen.2017.05.026. [Epub ahead of print].

Substrate properties of zebrafish Rtn4b/Nogo and axon regeneration in the zebrafish optic nerve

Authors:
Bodrikov V, Welte C, Wiechers M, Weschenfelder M, Kaur G, Shypitsyna A, Pinzon-Olejua A, Bastmeyer M, Stuermer CAO
Citation:
J Comp Neurol. 2017 May 30. doi: 10.1002/cne.24253. [Epub ahead of print]
Epub:
Yes
Abstract:
This study explored why lesioned retinal ganglion cell (RGC) axons regenerate successfully in the zebrafish optic nerve despite...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/cne.24253/abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Bodrikov V, Welte C, Wiechers M, Weschenfelder M, Kaur G, Shypitsyna A, Pinzon-Olejua A, Bastmeyer M, Stuermer CAO. Substrate properties of zebrafish Rtn4b/Nogo and axon regeneration in the zebrafish optic nerve. J Comp Neurol. 2017 May 30. doi: 10.1002/cne.24253. [Epub ahead of print].

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