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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

Authors:
Gong B, Shen W, Xiao W, Meng Y, Meng A, Jia S
Citation:
Elife. 2017 May 2;6. pii: e26362. doi: 10.7554/eLife.26362. [Epub ahead of print]
Epub:
Yes
Abstract:
The non-canonical Wnt/Ca2+ signaling pathway plays important roles in embryonic development, tissue formation and diseases....
Link:
https://elifesciences.org/content/6/e26362/article-data
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gong B, Shen W, Xiao W, Meng Y, Meng A, Jia S. The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling. Elife. 2017 May 2;6. pii: e26362. doi: 10.7554/eLife.26362. [Epub ahead of print].

An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations

Authors:
Stayner C, Poole CA, McGlashan SR, Pilanthananond M, Brauning R, Markie D, Lett B, Slobbe L, Chae A, Johnstone AC, Jensen CG, McEwan JC, Dittmer K, Parker K, Wiles A, Blackburne W, Leichter A, Leask M, Pinnapureddy A, Jennings M, Horsfield JA, Walker RJ, Eccles MR
Citation:
Sci Rep. 2017;7:1601. doi:10.1038/s41598-017-01519-4
Epub:
Not Epub
Abstract:
Meckel syndrome (MKS) is an inherited autosomal recessive hepatorenal fibrocystic syndrome, caused by mutations in TMEM67,...
Link:
https://www.nature.com/articles/s41598-017-01519-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stayner C, Poole CA, McGlashan SR, Pilanthananond M, Brauning R, Markie D, Lett B, Slobbe L, Chae A, Johnstone AC, Jensen CG, McEwan JC, Dittmer K, Parker K, Wiles A, Blackburne W, Leichter A, Leask M, Pinnapureddy A, Jennings M, Horsfield JA, Walker RJ, Eccles MR. An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations. Sci Rep. 2017;7:1601. doi:10.1038/s41598-017-01519-4.

Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling

Authors:
Rasouli SJ, Stainier DYR
Citation:
Nat Comm. 2017;8:15281 doi:10.1038/ncomms15281
Epub:
Not Epub
Abstract:
Trabeculation is crucial for cardiac muscle growth in vertebrates. This process requires the Erbb2/4 ligand Neuregulin (Nrg),...
Link:
https://www.nature.com/articles/ncomms15281
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rasouli SJ, Stainier DYR. Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling. Nat Comm. 2017;8:15281 doi:10.1038/ncomms15281.

The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells

Authors:
Pires PW, Ko E-A, Pritchard HAT, Rudokas M, Yamasaki E, Earley S
Citation:
J Physiol. 2017;[Epub ahead of print] doi:10.1113/JP274310
Epub:
Yes
Abstract:
Myogenic vasoconstriction, which reflects the intrinsic ability of smooth muscle cells to contract in response to increases in...
Link:
http://onlinelibrary.wiley.com/doi/10.1113/JP274310/abstract
Organism or Cell Type:
cell culture
Citation Extract:
Pires PW, Ko E-A, Pritchard HAT, Rudokas M, Yamasaki E, Earley S. The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells. J Physiol. 2017;[Epub ahead of print] doi:10.1113/JP274310.

Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following tdp-43 depletion

Authors:
Dzieciolowska S, Drapeau P, Armstrong GAB
Citation:
PLoS One. 2017 May 4;12(5):e0177005. doi: 10.1371/journal.pone.0177005. eCollection 2017
Epub:
Not Epub
Abstract:
TAR DNA binding protein (TDP-43) is a 43 kD, predominately nuclear, protein involved in RNA metabolism. Of clinical...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177005
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dzieciolowska S, Drapeau P, Armstrong GAB. Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following tdp-43 depletion. PLoS One. 2017 May 4;12(5):e0177005. doi: 10.1371/journal.pone.0177005. eCollection 2017.

Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish

Authors:
Bower NI, Koltowska K, Pichol-Thievend C, Virshup I, Paterson S, Lagendijk AK, Wang W, Lindsey BW, Bent SJ, Baek S, Rondon-Galeano M, Hurley DG, Mochizuki N, Simons C, Francois M, Wells CA, Kaslin J, Hogan BM
Citation:
Nat Neurosci. 2017 May 1. doi: 10.1038/nn.4558. [Epub ahead of print]
Epub:
Yes
Abstract:
Mural cells of the vertebrate brain maintain vascular integrity and function, play roles in stroke and are involved in...
Link:
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.4558.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bower NI, Koltowska K, Pichol-Thievend C, Virshup I, Paterson S, Lagendijk AK, Wang W, Lindsey BW, Bent SJ, Baek S, Rondon-Galeano M, Hurley DG, Mochizuki N, Simons C, Francois M, Wells CA, Kaslin J, Hogan BM. Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish. Nat Neurosci. 2017 May 1. doi: 10.1038/nn.4558. [Epub ahead of print].

USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling

Authors:
Zhou F, Xie F, Jin K, Zhang Z, Clerici M, Gao R, van Dinther M, Sixma TK, Huang H, Zhang L, ten Dijke P
Citation:
EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201695372
Epub:
Yes
Abstract:
SMAD4 is a common intracellular effector for TGF-β family cytokines, but the mechanism by which its activity is dynamically...
Link:
http://onlinelibrary.wiley.com/wol1/doi/10.15252/embj.201695372/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou F, Xie F, Jin K, Zhang Z, Clerici M, Gao R, van Dinther M, Sixma TK, Huang H, Zhang L, ten Dijke P. USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling. EMBO J. 2017;[Epub ahead of print] doi:10.15252/embj.201695372.

The Role of Oxytocin Neurons in the Bed Nucleus of the Stria Terminalis in Mediating Social Withdrawal

Authors:
Duque-Wilckens N, Steinman M, Grinevich V, Trainor B
Citation:
Biol Psychiat. 2017;81(10)suppl:S44-S45
Epub:
Not Epub
Abstract:
See link
Link:
http://www.biologicalpsychiatryjournal.com/article/S0006-3223(17)30238-X/abstract
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Duque-Wilckens N, Steinman M, Grinevich V, Trainor B. The Role of Oxytocin Neurons in the Bed Nucleus of the Stria Terminalis in Mediating Social Withdrawal. Biol Psychiat. 2017;81(10)suppl:S44-S45.

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

Authors:
Wiemann P, Perevitsky A, Lim FY, Shadkchan Y, Knox BP, Landero Figueora JA, Choera T, Niu M, Steinberger AJ, Wüthrich M, Idol RA, Klein BS, Dinauer MC, Huttenlocher A, Osherov N, Keller NP
Citation:
Cell Rep. 2017 May 2;19(5):1008-1021. doi: 10.1016/j.celrep.2017.04.019
Epub:
Not Epub
Abstract:
The Fenton-chemistry-generating properties of copper ions are considered a potent phagolysosome defense against pathogenic...
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(17)30494-1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wiemann P, Perevitsky A, Lim FY, Shadkchan Y, Knox BP, Landero Figueora JA, Choera T, Niu M, Steinberger AJ, Wüthrich M, Idol RA, Klein BS, Dinauer MC, Huttenlocher A, Osherov N, Keller NP. Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense. Cell Rep. 2017 May 2;19(5):1008-1021. doi: 10.1016/j.celrep.2017.04.019.

Importance of deubiquitinases in zebrafish craniofacial development

Authors:
Tse WKF
Citation:
Biochem Biophys Res Commun. 2017 Apr 24. pii: S0006-291X(17)30814-8. doi: 10.1016/j.bbrc.2017.04.132. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Deconjugation of ubiquitin and/or ubiqutin-like modified substrates is essential to maintain a sufficient free ubiquitin within...
Link:
http://www.sciencedirect.com/science/article/pii/S0006291X17308148
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tse WKF. Importance of deubiquitinases in zebrafish craniofacial development. Biochem Biophys Res Commun. 2017 Apr 24. pii: S0006-291X(17)30814-8. doi: 10.1016/j.bbrc.2017.04.132. [Epub ahead of print].

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