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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

A Novel Perivascular Cell Population in the Zebrafish Brain

Authors:
Galanternik MV, Castranova D, Gore AV, Blewett NH, Jung HM, Stratman AN, Kirby MR, Iben J, Miller MF, Kawakami K, Maraia RJ, Weinstein BM
Citation:
eLife. 2017;10.7554/eLife.24369 doi:10.7554/eLife.24369
Epub:
Not Epub
Abstract:
The blood-brain barrier is essential for the proper homeostasis and function of the CNS, but its mechanism of function is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Galanternik MV, Castranova D, Gore AV, Blewett NH, Jung HM, Stratman AN, Kirby MR, Iben J, Miller MF, Kawakami K, Maraia RJ, Weinstein BM. A Novel Perivascular Cell Population in the Zebrafish Brain. eLife. 2017;10.7554/eLife.24369 doi:10.7554/eLife.24369.

Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development

Authors:
Ferre-Fernández J-J, Aroca-Aguilar J-D, Medina-Trillo C, Bonet-Fernández J-M, Méndez-Hernández C-D, Morales-Fernández L, Corton M, Cabañero-Valera M-J, Gut M, Tonda R, Ayuso C, Coca-Prados M, García-Feijoo J, Escribano J
Citation:
Sci Rep. 2017;7:46175 doi:10.1038/srep46175
Epub:
Not Epub
Abstract:
Congenital glaucoma (CG) is a heterogeneous, inherited and severe optical neuropathy that originates from maldevelopment of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ferre-Fernández J-J, Aroca-Aguilar J-D, Medina-Trillo C, Bonet-Fernández J-M, Méndez-Hernández C-D, Morales-Fernández L, Corton M, Cabañero-Valera M-J, Gut M, Tonda R, Ayuso C, Coca-Prados M, García-Feijoo J, Escribano J. Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development. Sci Rep. 2017;7:46175 doi:10.1038/srep46175.

A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)

Authors:
Sandoval IT, Delacruz RGC, Miller BN, Hill S, Olson KA, Gabriel AE, Boyd K, Satterfield C, Van Remmen H, Rutter J, Jones DA
Citation:
eLife. 2017;6:e22706. doi:10.7554/eLife.22706
Epub:
Not Epub
Abstract:
Elucidating signaling pathways that regulate cellular metabolism is essential for a better understanding of normal development...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sandoval IT, Delacruz RGC, Miller BN, Hill S, Olson KA, Gabriel AE, Boyd K, Satterfield C, Van Remmen H, Rutter J, Jones DA. A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC). eLife. 2017;6:e22706. doi:10.7554/eLife.22706.

TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone

Authors:
Smith CJ, Wheeler MA, Marjoram L, Bagnat M, Deppmann CD, Kucenas S
Citation:
PLoS Genet. 2017 Apr 5;13(4):e1006712. doi: 10.1371/journal.pgen.1006712. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Somatosensory information from the periphery is routed to the spinal cord through centrally-projecting sensory axons that cross...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Smith CJ, Wheeler MA, Marjoram L, Bagnat M, Deppmann CD, Kucenas S. TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone. PLoS Genet. 2017 Apr 5;13(4):e1006712. doi: 10.1371/journal.pgen.1006712. [Epub ahead of print].

The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger

Authors:
Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ
Citation:
Nat Commun. 2017 Apr 6;8:14911. doi: 10.1038/ncomms14911
Epub:
Not Epub
Abstract:
In response to infection and injury, the neutrophil population rapidly expands and then quickly re-establishes the basal state...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Keightley MC, Carradice DP, Layton JE, Pase L, Bertrand JY, Wittig JG, Dakic A, Badrock AP, Cole NJ, Traver D, Nutt SL, McCoey J, Buckle AM, Heath JK, Lieschke GJ. The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger. Nat Commun. 2017 Apr 6;8:14911. doi: 10.1038/ncomms14911.

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes

Authors:
Witzel M, Petersheim D, Fan Y, Bahrami E, Racek T, Rohlfs M, Puchałka J, Mertes C, Gagneur J, Ziegenhain C, Enard W, Stray-Pedersen A, Arkwright PD, Abboud MR, Pazhakh V, Lieschke GJ, Krawitz PM, Dahlhoff M, Schneider MR, Wolf E, Horny HP, Schmidt H, Schäffer AA, Klein C
Citation:
Nat Genet. 2017 Apr 3. doi: 10.1038/ng.3833. [Epub ahead of print]
Epub:
Yes
Abstract:
We identify SMARCD2 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily D, member 2), also...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Witzel M, Petersheim D, Fan Y, Bahrami E, Racek T, Rohlfs M, Puchałka J, Mertes C, Gagneur J, Ziegenhain C, Enard W, Stray-Pedersen A, Arkwright PD, Abboud MR, Pazhakh V, Lieschke GJ, Krawitz PM, Dahlhoff M, Schneider MR, Wolf E, Horny HP, Schmidt H, Schäffer AA, Klein C. Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes. Nat Genet. 2017 Apr 3. doi: 10.1038/ng.3833. [Epub ahead of print].

Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis

Authors:
Sidhaye J, Norden C
Citation:
Elife. 2017 Apr 4;6. pii: e22689. doi: 10.7554/eLife.22689
Epub:
Not Epub
Abstract:
Organ formation is a multi-scale event that involves changes at the intracellular, cellular and tissue level. Organogenesis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sidhaye J, Norden C. Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis. Elife. 2017 Apr 4;6. pii: e22689. doi: 10.7554/eLife.22689.

In vivo characterization of an AHR-dependent long non-coding RNA required for proper Sox9b expression

Authors:
Garcia GR, Goodale BC, Wiley MW, La Du JK, Hendrix DA, Tanguay RL
Citation:
Mol Pharmacol. 2017 Apr 6. pii: mol.117.108233. doi: 10.1124/mol.117.108233. [Epub ahead of print]
Epub:
Yes
Abstract:
Xenobiotic activation of the aryl hydrocarbon receptor (AHR) by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) prevents the proper...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Garcia GR, Goodale BC, Wiley MW, La Du JK, Hendrix DA, Tanguay RL. In vivo characterization of an AHR-dependent long non-coding RNA required for proper Sox9b expression. Mol Pharmacol. 2017 Apr 6. pii: mol.117.108233. doi: 10.1124/mol.117.108233. [Epub ahead of print].

Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?

Authors:
Shi X, Verma S, Yun J, Brand-Arzamendi K, Singh KK, Liu X, Garg A, Quan A, Wen XY
Citation:
Mol Cell Biochem. 2017 Apr 8. doi: 10.1007/s11010-017-3018-9. [Epub ahead of print]
Epub:
Yes
Abstract:
The sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin was recently reported to reduce heart failure-associated...
Organism or Cell Type:
zebrafish
Citation Extract:
Shi X, Verma S, Yun J, Brand-Arzamendi K, Singh KK, Liu X, Garg A, Quan A, Wen XY. Effect of empagliflozin on cardiac biomarkers in a zebrafish model of heart failure: clues to the EMPA-REG OUTCOME trial?. Mol Cell Biochem. 2017 Apr 8. doi: 10.1007/s11010-017-3018-9. [Epub ahead of print].

Ca2+ release via two-pore channel type 2 (TPC2) is required for slow muscle cell myofibrillogenesis and myotomal patterning in intact zebrafish embryos

Authors:
Kelu JJ, Webb SE, Parrington J, Galione A, Miller AL
Citation:
Dev Biol. 2017 Apr 5. pii: S0012-1606(16)30821-1. doi: 10.1016/j.ydbio.2017.03.031. [Epub ahead of print]
Epub:
Yes
Abstract:
We recently demonstrated a critical role for two-pore channel type 2 (TPC2)-mediated Ca2+ release during the differentiation of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kelu JJ, Webb SE, Parrington J, Galione A, Miller AL. Ca2+ release via two-pore channel type 2 (TPC2) is required for slow muscle cell myofibrillogenesis and myotomal patterning in intact zebrafish embryos. Dev Biol. 2017 Apr 5. pii: S0012-1606(16)30821-1. doi: 10.1016/j.ydbio.2017.03.031. [Epub ahead of print].

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