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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Zebrafish Mecp2 is required for proper axonal elongation of motor neurons and synapse formation
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Citation:
Dev Neurobiol. 2017 Apr 2. doi: 10.1002/dneu.22498. [Epub ahead of print] Epub:
Yes Abstract:
Rett syndrome is a severe neurodevelopmental disorder. It is caused by a mutation in methyl-CpG binding protein 2 (MecP2), a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nozawa K, Lin Y, Kubodera R, Shimizu Y, Tanaka H, Ohshima T. Zebrafish Mecp2 is required for proper axonal elongation of motor neurons and synapse formation. Dev Neurobiol. 2017 Apr 2. doi: 10.1002/dneu.22498. [Epub ahead of print]. |
The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5)
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Citation:
Gene. 2017 Mar 30. pii: S0378-1119(17)30217-2. doi: 10.1016/j.gene.2017.03.037. [Epub ahead of print] Epub:
Yes Abstract:
Insulin-like growth factor (IGF) binding proteins (IGFBPs) constitute a family of six secreted proteins that regulate the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse kidney explant Citation Extract: Müller M, Persson AB, Krueger K, Kirschner KM, Scholz H. The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5). Gene. 2017 Mar 30. pii: S0378-1119(17)30217-2. doi: 10.1016/j.gene.2017.03.037. [Epub ahead of print]. |
In Vivo Imaging of Transgenic Gene Expression in Individual Retinal Progenitors in Chimeric Zebrafish Embryos to Study Cell Nonautonomous Influences
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Citation:
J Vis Exp. 2017 Mar 22;(121). doi: 10.3791/55490 Epub:
Not Epub Abstract:
The genetic and technical strengths have made the zebrafish vertebrate a key model organism in which the consequences of gene... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dudczig S, Currie PD, Poggi L, Jusuf PR. In Vivo Imaging of Transgenic Gene Expression in Individual Retinal Progenitors in Chimeric Zebrafish Embryos to Study Cell Nonautonomous Influences. J Vis Exp. 2017 Mar 22;(121). doi: 10.3791/55490. |
Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects
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Citation:
J Mol Cell Cardiol. 2017 Mar 27;106:1-13. doi: 10.1016/j.yjmcc.2017.03.006. [Epub ahead of print] Epub:
Not Epub Abstract:
Tropomyosin 1 (TPM1) is an essential sarcomeric component, stabilising the thin filament and facilitating actin's... Delivery Method:
pluronic gel Organism or Cell Type:
Gallus gallus (chick) Citation Extract: England J, Granados-Riveron J, Polo-Parada L, Kuriakose D, Moore C, Brook JD, Rutland CS, Setchfield K, Gell C, Ghosh TK, Bu'Lock F, Thornborough C, Ehler E, Loughna S. Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects. J Mol Cell Cardiol. 2017 Mar 27;106:1-13. doi: 10.1016/j.yjmcc.2017.03.006. [Epub ahead of print]. |
Wnt8a expands the pool of embryonic kidney progenitors in zebrafish
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Citation:
Dev Biol. 2017 Mar 27. pii: S0012-1606(16)30674-1. doi: 10.1016/j.ydbio.2017.03.027. [Epub ahead of print] Epub:
Yes Abstract:
During zebrafish embryogenesis the pronephric kidney arises from a small population of posterior mesoderm cells that then... Organism or Cell Type:
zebrafish Citation Extract: Naylor RW, Han HI, Hukriede NA, Davidson AJ. Wnt8a expands the pool of embryonic kidney progenitors in zebrafish. Dev Biol. 2017 Mar 27. pii: S0012-1606(16)30674-1. doi: 10.1016/j.ydbio.2017.03.027. [Epub ahead of print]. |
Semaphorin4D promotes axon regrowth and swimming ability during recovery following zebrafish spinal cord injury
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Citation:
Neuroscience. 2017 Mar 25. pii: S0306-4522(17)30196-3. doi: 10.1016/j.neuroscience.2017.03.030. [Epub ahead of print] Epub:
Not Epub Abstract:
Semaphorins comprise a family of proteins involved in axon guidance during development. Semaphorin4D (Sema4D) has both... Organism or Cell Type:
zebrafish Citation Extract: Peng SX, Yao L, Cui C, Zhao HD, Liu CJ, Li YH, Wang LF, Huang SB, Shen YQ. Semaphorin4D promotes axon regrowth and swimming ability during recovery following zebrafish spinal cord injury. Neuroscience. 2017 Mar 25. pii: S0306-4522(17)30196-3. doi: 10.1016/j.neuroscience.2017.03.030. [Epub ahead of print]. |
Ultrasensitive Hybridization-Based ELISA Method for the Determination of Phosphorodiamidate Morpholino Oligonucleotides in Biological samples
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Citation:
Methods Mol Biol. 2017;1565:265-277. doi: 10.1007/978-1-4939-6817-6_22 Epub:
Not Epub Abstract:
Determining the concentration of oligonucleotide in biological samples such as tissue lysate and serum is essential for... Citation Extract: Burki U, Straub V. Ultrasensitive Hybridization-Based ELISA Method for the Determination of Phosphorodiamidate Morpholino Oligonucleotides in Biological samples. Methods Mol Biol. 2017;1565:265-277. doi: 10.1007/978-1-4939-6817-6_22. |
Surface Plasmon Resonance-Based Concentration Determination Assay: Label-Free and Antibody-Free Quantification of Morpholinos
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Citation:
Methods Mol Biol. 2017;1565:251-263. doi: 10.1007/978-1-4939-6817-6_21 Epub:
Not Epub Abstract:
Surface plasmon resonance (SPR) is a physical process that allows label-free and real-time detection of biomolecular... Citation Extract: Boutilier J, Moulton HM. Surface Plasmon Resonance-Based Concentration Determination Assay: Label-Free and Antibody-Free Quantification of Morpholinos. Methods Mol Biol. 2017;1565:251-263. doi: 10.1007/978-1-4939-6817-6_21. |
Delivery of Morpholino Antisense Oligonucleotides to a Developing Ovine Conceptus via Luminal Injection into a Ligated Uterine Horn
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Citation:
Methods Mol Biol. 2017;1565:241-250. doi: 10.1007/978-1-4939-6817-6_20 Epub:
Not Epub Abstract:
In vivo delivery of morpholino antisense oligonucleotides (MAO) directly into the uterine lumen of a peri-implantation period... Delivery Method:
Endo-Porter Organism or Cell Type:
Ovis aries (sheep) Citation Extract: Wang X, Dunlap KA. Delivery of Morpholino Antisense Oligonucleotides to a Developing Ovine Conceptus via Luminal Injection into a Ligated Uterine Horn. Methods Mol Biol. 2017;1565:241-250. doi: 10.1007/978-1-4939-6817-6_20. |
Intracerebroventricular Delivery in Mice for Motor Neuron Diseases
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Citation:
Methods Mol Biol. 2017;1565:229-239. doi: 10.1007/978-1-4939-6817-6_19 Epub:
Not Epub Abstract:
The use of antisense oligonucleotides to target specific mRNA sequences represents a promising therapeutic strategy for... Delivery Method:
intracerebroventricular injection Organism or Cell Type:
mice Citation Extract: Nizzardo M, Rizzuti M. Intracerebroventricular Delivery in Mice for Motor Neuron Diseases. Methods Mol Biol. 2017;1565:229-239. doi: 10.1007/978-1-4939-6817-6_19. |