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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

In Vivo and Explant Electroporation of Morpholinos in the Developing Mouse Retina

Authors:
Karunakaran DK, Kanadia R
Citation:
Methods Mol Biol. 2017;1565:215-227. doi: 10.1007/978-1-4939-6817-6_18
Epub:
Not Epub
Abstract:
Neonatal in vivo electroporations and retinal explant electroporations have been widely employed in understanding the effects...
Delivery Method:
electroporation
Organism or Cell Type:
mice
Citation Extract:
Karunakaran DK, Kanadia R. In Vivo and Explant Electroporation of Morpholinos in the Developing Mouse Retina. Methods Mol Biol. 2017;1565:215-227. doi: 10.1007/978-1-4939-6817-6_18.

Systemic Delivery of Morpholinos to Skip Multiple Exons in a Dog Model of Duchenne Muscular Dystrophy

Authors:
Maruyama R, Echigoya Y, Caluseriu O, Aoki Y, Takeda S, Yokota T
Citation:
Methods Mol Biol. 2017;1565:201-213. doi: 10.1007/978-1-4939-6817-6_17
Epub:
Not Epub
Abstract:
Exon-skipping therapy is an emerging approach that uses synthetic DNA-like molecules called antisense oligonucleotides (AONs)...
Delivery Method:
injection, peptide-linked
Organism or Cell Type:
Canis familiaris (dog)
Citation Extract:
Maruyama R, Echigoya Y, Caluseriu O, Aoki Y, Takeda S, Yokota T. Systemic Delivery of Morpholinos to Skip Multiple Exons in a Dog Model of Duchenne Muscular Dystrophy. Methods Mol Biol. 2017;1565:201-213. doi: 10.1007/978-1-4939-6817-6_17.

Intranasal Delivery of Peptide-Morpholinos to Knockdown Influenza Host Factors in Mice

Authors:
Rajsbaum R
Citation:
Methods Mol Biol. 2017;1565:191-199. doi: 10.1007/978-1-4939-6817-6_16
Epub:
Not Epub
Abstract:
Influenza viruses replicate primarily in the lung tissue of different host species. For efficient replication the virus...
Delivery Method:
peptide-linked
Organism or Cell Type:
mice
Citation Extract:
Rajsbaum R. Intranasal Delivery of Peptide-Morpholinos to Knockdown Influenza Host Factors in Mice. Methods Mol Biol. 2017;1565:191-199. doi: 10.1007/978-1-4939-6817-6_16.

Diagnostic Applications of Morpholinos and Label-Free Electrochemical Detection of Nucleic Acids

Authors:
Levicky R, Koniges U, Tercero N
Citation:
Methods Mol Biol. 2017;1565:181-190. doi: 10.1007/978-1-4939-6817-6_15
Epub:
Not Epub
Abstract:
Diagnostic applications of morpholinos take advantage of their unique properties including backbone charge neutrality, a weak...
Citation Extract:
Levicky R, Koniges U, Tercero N. Diagnostic Applications of Morpholinos and Label-Free Electrochemical Detection of Nucleic Acids. Methods Mol Biol. 2017;1565:181-190. doi: 10.1007/978-1-4939-6817-6_15.

Use of Morpholino Oligomers for Pretargeting

Authors:
Liu G
Citation:
Methods Mol Biol. 2017;1565:161-179. doi: 10.1007/978-1-4939-6817-6_14
Epub:
Not Epub
Abstract:
Differing from the conventional direct-targeting strategy in which a probe or payload is directly loaded onto a targeting...
Delivery Method:
injection
Organism or Cell Type:
mice
Citation Extract:
Liu G. Use of Morpholino Oligomers for Pretargeting. Methods Mol Biol. 2017;1565:161-179. doi: 10.1007/978-1-4939-6817-6_14.

Targeting Functional Noncoding RNAs

Authors:
Crossley MP, Krude T
Citation:
Methods Mol Biol. 2017;1565:151-160. doi: 10.1007/978-1-4939-6817-6_13
Epub:
Not Epub
Abstract:
Noncoding RNAs have essential biochemical functions in different areas of cellular metabolism, including protein synthesis, RNA...
Organism or Cell Type:
Danio rerio, Xenopus laevis, Caenorhabditis elegans
Citation Extract:
Crossley MP, Krude T. Targeting Functional Noncoding RNAs. Methods Mol Biol. 2017;1565:151-160. doi: 10.1007/978-1-4939-6817-6_13.

Regulation of Isoform Expression by Blocking Polyadenylation Signal Sequences with Morpholinos

Authors:
Gong Q, Zhou Z
Citation:
Methods Mol Biol. 2017;1565:141-150. doi: 10.1007/978-1-4939-6817-6_12
Epub:
Not Epub
Abstract:
Alternative polyadenylation is increasingly being recognized as an important layer of gene regulation. Antisense-mediated...
Citation Extract:
Gong Q, Zhou Z. Regulation of Isoform Expression by Blocking Polyadenylation Signal Sequences with Morpholinos. Methods Mol Biol. 2017;1565:141-150. doi: 10.1007/978-1-4939-6817-6_12.

Use of Translation Blocking Morpholinos for Gene Knockdown in Giardia lamblia

Authors:
Krtková J, Paredez AR
Citation:
Methods Mol Biol. 2017;1565:123-140. doi: 10.1007/978-1-4939-6817-6_11
Epub:
Not Epub
Abstract:
Giardia lamblia, a major parasite, is an emerging model organism due to its compact genomic arrangement and composition. The...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Krtková J, Paredez AR. Use of Translation Blocking Morpholinos for Gene Knockdown in Giardia lamblia. Methods Mol Biol. 2017;1565:123-140. doi: 10.1007/978-1-4939-6817-6_11.

Inhibition of Bacterial Growth by Peptide-Conjugated Morpholino Oligomers

Authors:
Daly SM, Sturge CR, Greenberg DE
Citation:
Methods Mol Biol. 2017;1565:115-122. doi: 10.1007/978-1-4939-6817-6_10
Epub:
Not Epub
Abstract:
Morpholino oligomers (MOs) are antisense molecules designed for sequence-specific binding of target mRNA. In bacteria,...
Delivery Method:
peptide-linked
Organism or Cell Type:
bacteria
Citation Extract:
Daly SM, Sturge CR, Greenberg DE. Inhibition of Bacterial Growth by Peptide-Conjugated Morpholino Oligomers. Methods Mol Biol. 2017;1565:115-122. doi: 10.1007/978-1-4939-6817-6_10.

Manipulating Gene Expression in the Chick Embryo

Authors:
Voiculescu O, Stern CD
Citation:
Methods Mol Biol. 2017;1565:105-114. doi: 10.1007/978-1-4939-6817-6_9
Epub:
Not Epub
Abstract:
The chick embryo is a well-established representative of amniote embryos, which has been used to make many discoveries,...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Voiculescu O, Stern CD. Manipulating Gene Expression in the Chick Embryo. Methods Mol Biol. 2017;1565:105-114. doi: 10.1007/978-1-4939-6817-6_9.

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