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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Combination of valproic acid and morpholino splice-switching oligonucleotide produces improved outcomes in spinal muscular atrophy patient-derived fibroblasts
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Citation:
Neurochem Int. 2017 Apr 4. pii: S0197-0186(17)30035-9. doi: 10.1016/j.neuint.2017.02.016. [Epub ahead of print] Epub:
Yes Abstract:
Spinal muscular atrophy (SMA), the leading genetic cause of infant mortality worldwide, is characterised by the homozygous loss... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: primary human fibroblasts Citation Extract: Farrelly-Rosch A, Lau CL, Patil N, Turner BJ, Shabanpoor F. Combination of valproic acid and morpholino splice-switching oligonucleotide produces improved outcomes in spinal muscular atrophy patient-derived fibroblasts. Neurochem Int. 2017 Apr 4. pii: S0197-0186(17)30035-9. doi: 10.1016/j.neuint.2017.02.016. [Epub ahead of print]. |
Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy
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Citation:
Cell Chem Biol. 2017 Mar 22. pii: S2451-9456(17)30068-5. doi: 10.1016/j.chembiol.2017.03.005. [Epub ahead of print] Epub:
Yes Abstract:
Stimulating autophagy is a promising therapeutic strategy for slowing the progression of neurodegenerative disease. Neurons are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Y, Nguyen DT, Olzomer EM, Poon GP, Cole NJ, Puvanendran A, Phillips BR, Hesselson D. Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy. Cell Chem Biol. 2017 Mar 22. pii: S2451-9456(17)30068-5. doi: 10.1016/j.chembiol.2017.03.005. [Epub ahead of print]. |
PCR artifact in testing for homologous recombination in genomic editing in zebrafish
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Citation:
PLoS One. 2017 Mar 31;12(3):e0172802. doi: 10.1371/journal.pone.0172802. eCollection 2017 Epub:
Not Epub Abstract:
We report a PCR-induced artifact in testing for homologous recombination in zebrafish. We attempted to replace the lnx2a gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Won M, Dawid IB. PCR artifact in testing for homologous recombination in genomic editing in zebrafish. PLoS One. 2017 Mar 31;12(3):e0172802. doi: 10.1371/journal.pone.0172802. eCollection 2017. |
Modulation of Endothelial BMPR2 Activity by VEGFR3 in Pulmonary Arterial Hypertension
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Citation:
Circulation. 2017 Mar 29. pii: CIRCULATIONAHA.116.025390. doi: 10.1161/CIRCULATIONAHA.116.025390. [Epub ahead of print] Epub:
Yes Abstract:
Background -Bone Morphogenetic Protein (BMP) signaling has multiple roles in the development and function of the blood vessels... Organism or Cell Type:
zebrafish Citation Extract: Hwangbo C, Lee HW, Kang H, Ju H, Wiley DS, Papangeli I, Han J, Kim JD, Dunworth WP, Hu X, Lee S, El-Hely O, Sofer A, Pak B, Peterson L, Comhair S, Hwang EM, Park JY, Thomas JL, Bautch VL, Erzurum SC, Chun HJ, Jin SW. Modulation of Endothelial BMPR2 Activity by VEGFR3 in Pulmonary Arterial Hypertension. Circulation. 2017 Mar 29. pii: CIRCULATIONAHA.116.025390. doi: 10.1161/CIRCULATIONAHA.116.025390. [Epub ahead of print]. |
Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells
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Citation:
Elife. 2017 Mar 29;6. pii: e21620. doi: 10.7554/eLife.21620 Epub:
Not Epub Abstract:
The 'neural plate border' of vertebrate embryos contains precursors of neural crest and placode cells, both defining... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Roellig D, Tan-Cabugao J, Esaian S, Bronner ME. Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells. Elife. 2017 Mar 29;6. pii: e21620. doi: 10.7554/eLife.21620. |
Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS
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Citation:
PLoS One. 2017 Mar 30;12(3):e0174784. doi: 10.1371/journal.pone.0174784. eCollection 2017 Epub:
Not Epub Abstract:
Progranulin (PGRN) is a glycoprotein with multiple roles in normal and disease states. Mutations within the GRN gene cause... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chitramuthu BP, Kay DG, Bateman A, Bennett HP. Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS. PLoS One. 2017 Mar 30;12(3):e0174784. doi: 10.1371/journal.pone.0174784. eCollection 2017. |
Correction: Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes
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Citation:
PLoS One. 2017 Apr 6;12(4):e0175608. doi: 10.1371/journal.pone.0175608. eCollection 2017 Epub:
Not Epub Abstract:
No abstract available. The correction provides missing Morpholino sequences. Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Place ES, Smith JC. Correction: Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes. PLoS One. 2017 Apr 6;12(4):e0175608. doi: 10.1371/journal.pone.0175608. eCollection 2017. |
Progranulin regulates neurogenesis in the developing vertebrate retina
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Citation:
Dev Neurobiol. 2017 Apr 5. doi: 10.1002/dneu.22499. [Epub ahead of print] Epub:
Not Epub Abstract:
We evaluated the expression and function of the microglia-specific growth factor, Progranulin-a (Pgrn-a) during developmental... Organism or Cell Type:
zebrafish Citation Extract: Walsh CE, Hitchcock PF. Progranulin regulates neurogenesis in the developing vertebrate retina. Dev Neurobiol. 2017 Apr 5. doi: 10.1002/dneu.22499. [Epub ahead of print]. |
Aipl1 is required for cone photoreceptor function and survival through the stability of Pde6c and Gc3 in zebrafish
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Citation:
Sci Rep. 2017 Apr 5;7:45962. doi: 10.1038/srep45962 Epub:
Not Epub Abstract:
Genetic mutations in aryl hydrocarbon receptor interacting protein-like 1 (AIPL1) cause photoreceptor degeneration associated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Iribarne M, Nishiwaki Y, Nakamura S, Araragi M, Oguri E, Masai I. Aipl1 is required for cone photoreceptor function and survival through the stability of Pde6c and Gc3 in zebrafish. Sci Rep. 2017 Apr 5;7:45962. doi: 10.1038/srep45962. |
Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy
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Citation:
Proc Natl Acad Sci U S A. 2017 Apr 3. pii: 201613203. doi: 10.1073/pnas.1613203114. [Epub ahead of print] Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a lethal genetic disorder caused by an absence of the dystrophin protein in bodywide... Delivery Method:
peptide-linked, bare oligo injection Organism or Cell Type:
Canis familiaris (dog) Citation Extract: Echigoya Y, Nakamura A, Nagata T, Urasawa N, Lim KR, Trieu N, Panesar D, Kuraoka M, Moulton HM, Saito T, Aoki Y, Iversen P, Sazani P, Kole R, Maruyama R, Partridge T, Takeda S, Yokota T. Effects of systemic multiexon skipping with peptide-conjugated morpholinos in the heart of a dog model of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2017 Apr 3. pii: 201613203. doi: 10.1073/pnas.1613203114. [Epub ahead of print]. |