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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy

Authors:
Boyd PJ, Tu W-Y, Shorrock HK, Groen EJN, Carter RN, Powis RA, Thomson SR, Thomson D, Graham LC, Motyl AAL, Wishart TM, Highley JR, Morton NM, Becker T, Becker CG, Heath PR, Gillingwater TH
Citation:
PLoS Genet. 2017;[uncorrected proof] doi:10.1371/journal.pgen.1006744
Epub:
Not Epub
Abstract:
Degeneration and loss of lower motor neurons is the major pathological hallmark of spinal muscular atrophy (SMA), resulting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boyd PJ, Tu W-Y, Shorrock HK, Groen EJN, Carter RN, Powis RA, Thomson SR, Thomson D, Graham LC, Motyl AAL, Wishart TM, Highley JR, Morton NM, Becker T, Becker CG, Heath PR, Gillingwater TH. Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy. PLoS Genet. 2017;[uncorrected proof] doi:10.1371/journal.pgen.1006744.

Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain

Authors:
Albuixech-Crespo B, López-Blanch L, Burguera D, Maeso I, Sánchez-Arrones L, Moreno-Bravo JA, Somorjai I, Pascual-Anaya J, Puelles E, Bovolenta P, Garcia-Fernàndez J, Puelles L, Irimia M, Ferran JL
Citation:
PLoS Biol. 2017;15(4):e2001573. doi:10.1371/journal.pbio.2001573
Epub:
Not Epub
Abstract:
All vertebrate brains develop following a common Bauplan defined by anteroposterior (AP) and dorsoventral (DV) subdivisions,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Albuixech-Crespo B, López-Blanch L, Burguera D, Maeso I, Sánchez-Arrones L, Moreno-Bravo JA, Somorjai I, Pascual-Anaya J, Puelles E, Bovolenta P, Garcia-Fernàndez J, Puelles L, Irimia M, Ferran JL. Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain. PLoS Biol. 2017;15(4):e2001573. doi:10.1371/journal.pbio.2001573.

An Integrative Developmental Genomics and Systems Biology Approach To Identify An In Vivo Sox Trio-Mediated Gene Regulatory Network In Murine Embryos

Authors:
Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PP, Prabhakar S, Lufkin T
Citation:
BioMed Res Internat. 2017;[Epub ahead of print]
Epub:
Yes
Abstract:
Embryogenesis is an intricate process involving multiple genes and pathways. Some of the key transcription factors controlling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PP, Prabhakar S, Lufkin T. An Integrative Developmental Genomics and Systems Biology Approach To Identify An In Vivo Sox Trio-Mediated Gene Regulatory Network In Murine Embryos. BioMed Res Internat. 2017;[Epub ahead of print] .

A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder

Authors:
Yang L, Chang S, Lu Q, Zhang Y, Wu Z, Sun X, Cao Q, Qian Y, Jia T, Xu B, Duan Q, Li Y, Zhang K, Schumann G, Liu D, Wang J, Wang Y, Lu L
Citation:
Molec Psychiatry. 2017;[Epub ahead of print] doi:10.1038/mp.2017.74
Epub:
Yes
Abstract:
Impaired executive inhibition is a core deficit of attention deficit hyperactivity disorder (ADHD), which is a common childhood...
Organism or Cell Type:
zebrafish
Citation Extract:
Yang L, Chang S, Lu Q, Zhang Y, Wu Z, Sun X, Cao Q, Qian Y, Jia T, Xu B, Duan Q, Li Y, Zhang K, Schumann G, Liu D, Wang J, Wang Y, Lu L. A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder. Molec Psychiatry. 2017;[Epub ahead of print] doi:10.1038/mp.2017.74.

Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos

Authors:
Joseph SR, Pálfy M, Hilbert L, Kumar M, Karschau J, Zaburdaev V, Shevchenko A, Vastenhouw NL
Citation:
bioRxiv. 2017;doi:10.1101/125716
Epub:
Not Epub
Abstract:
Upon fertilization, the genome of animal embryos remains transcriptionally inactive until the maternal-to-zygotic transition....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Joseph SR, Pálfy M, Hilbert L, Kumar M, Karschau J, Zaburdaev V, Shevchenko A, Vastenhouw NL. Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos. bioRxiv. 2017;doi:10.1101/125716.

Sequential Response to Multiple Developmental Network Circuits Encoded in an Intronic cis-Regulatory Module of Sea Urchin hox11/13b

Authors:
Cui M, Vielmas E, Davidson EH, Peter IS
Citation:
Cell Rep. 2017;19:364-74. doi:10.1016/j.celrep.2017.03.039
Epub:
Not Epub
Abstract:
Gene expression in different spatial domains is often controlled by separate cis-regulatory modules (CRMs), but regulatory...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Cui M, Vielmas E, Davidson EH, Peter IS. Sequential Response to Multiple Developmental Network Circuits Encoded in an Intronic cis-Regulatory Module of Sea Urchin hox11/13b. Cell Rep. 2017;19:364-74. doi:10.1016/j.celrep.2017.03.039.

Sexual dimorphic expression of dnd in germ cells during sex reversal and its requirement for primordial germ cell survival in protogynous hermaphroditic grouper

Authors:
Sun ZH, Zhou L, Li Z, Liu XC, Li SS, Wang Y, Gui JF
Citation:
Comp Biochem Physiol B Biochem Mol Biol. 2017 Apr 8. pii: S1096-4959(17)30050-7. doi: 10.1016/j.cbpb.2017.04.003. [Epub ahead of print]
Epub:
Yes
Abstract:
Dead end (dnd), vertebrate-specific germ cell marker, had been demonstrated to be essential for primordial germ cell (PGC)...
Organism or Cell Type:
Epinephelus coioides (orange-spotted grouper)
Citation Extract:
Sun ZH, Zhou L, Li Z, Liu XC, Li SS, Wang Y, Gui JF. Sexual dimorphic expression of dnd in germ cells during sex reversal and its requirement for primordial germ cell survival in protogynous hermaphroditic grouper. Comp Biochem Physiol B Biochem Mol Biol. 2017 Apr 8. pii: S1096-4959(17)30050-7. doi: 10.1016/j.cbpb.2017.04.003. [Epub ahead of print].

Distinct and redundant functions of Esam and VE-cadherin during vascular morphogenesis

Authors:
Sauteur L, Affolter M, Belting HG
Citation:
Development. 2017 Mar 6. pii: dev.140038. doi: 10.1242/dev.140038. [Epub ahead of print]
Epub:
Yes
Abstract:
The cardiovascular system forms during early embryogenesis and adapts to embryonic growth by sprouting angiogenesis and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sauteur L, Affolter M, Belting HG. Distinct and redundant functions of Esam and VE-cadherin during vascular morphogenesis. Development. 2017 Mar 6. pii: dev.140038. doi: 10.1242/dev.140038. [Epub ahead of print].

A systems level approach reveals new gene regulatory modules in the developing ear

Authors:
Chen J, Tambalo M, Barembaum M, Ranganathan R, Simões-Costa M, Bronner ME, Streit A
Citation:
Development. 2017 Mar 6. pii: dev.148494. doi: 10.1242/dev.148494. [Epub ahead of print]
Epub:
Yes
Abstract:
The inner ear is a complex vertebrate sense organ, yet arises from a simple epithelium, the otic placode. Specification towards...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Chen J, Tambalo M, Barembaum M, Ranganathan R, Simões-Costa M, Bronner ME, Streit A. A systems level approach reveals new gene regulatory modules in the developing ear. Development. 2017 Mar 6. pii: dev.148494. doi: 10.1242/dev.148494. [Epub ahead of print].

Xenopus Vasa Homolog XVLG1 is Essential for Migration and Survival of Primordial Germ Cells

Authors:
Shimaoka K, Mukumoto Y, Tanigawa Y, Komiya T
Citation:
Zoolog Sci. 2017 Apr;34(2):93-104. doi: 10.2108/zs160198
Epub:
Not Epub
Abstract:
Xenopus vasa-like gene 1 (XVLG1), a DEAD-Box Helicase 4 (DDX4) gene identified as a vertebrate vasa homologue, is required for...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Shimaoka K, Mukumoto Y, Tanigawa Y, Komiya T. Xenopus Vasa Homolog XVLG1 is Essential for Migration and Survival of Primordial Germ Cells. Zoolog Sci. 2017 Apr;34(2):93-104. doi: 10.2108/zs160198.

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