You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Brorin is required for neurogenesis, gliogenesis, and commissural axon guidance in the zebrafish forebrain

Authors:
Miyake A, Mekata Y, Fujibayashi H, Nakanishi K, Konishi M, Itoh N
Citation:
PLoS One. 2017 Apr 27;12(4):e0176036. doi: 10.1371/journal.pone.0176036. eCollection 2017
Epub:
Not Epub
Abstract:
Bmps regulate numerous neural functions with their regulators. We previously identified Brorin, a neural-specific secreted...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176036
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyake A, Mekata Y, Fujibayashi H, Nakanishi K, Konishi M, Itoh N. Brorin is required for neurogenesis, gliogenesis, and commissural axon guidance in the zebrafish forebrain. PLoS One. 2017 Apr 27;12(4):e0176036. doi: 10.1371/journal.pone.0176036. eCollection 2017.

Role of CC Cytokines in Spatial Arrangement of the Inner Cell Mass of the Bovine Embryo

Authors:
Negrón-Pérez VM, Vargas-Franco D, Hansen PJ
Citation:
Biol Reprod. 2017 Apr 25. doi: 10.1093/biolre/iox037. [Epub ahead of print]
Epub:
Yes
Abstract:
The process of spatial rearrangement of cells of the inner cell mass (ICM) that are destined to become hypoblast is not well...
Link:
https://academic.oup.com/biolreprod/article-abstract/doi/10.1093/biolre/iox037/3752503/Role-of-CC-Cytokines-in-Spatial-Arrangement-of-the
Delivery Method:
microinjection
Organism or Cell Type:
Bos taurus (cattle)
Citation Extract:
Negrón-Pérez VM, Vargas-Franco D, Hansen PJ. Role of CC Cytokines in Spatial Arrangement of the Inner Cell Mass of the Bovine Embryo. Biol Reprod. 2017 Apr 25. doi: 10.1093/biolre/iox037. [Epub ahead of print].

Characterization and expression analysis of Galnts in developing Strongylocentrotus purpuratus embryos

Authors:
Famiglietti AL, Wei Z, Beres TM, Milac AL, Tran DT, Patel D, Angerer RC, Angerer LM, Tabak LA
Citation:
PLoS One. 2017 Apr 27;12(4):e0176479. doi: 10.1371/journal.pone.0176479. eCollection 2017
Epub:
Not Epub
Abstract:
Mucin-type O-glycosylation is a ubiquitous posttranslational modification in which N-Acetylgalactosamine (GalNAc) is added to...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176479
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Famiglietti AL, Wei Z, Beres TM, Milac AL, Tran DT, Patel D, Angerer RC, Angerer LM, Tabak LA. Characterization and expression analysis of Galnts in developing Strongylocentrotus purpuratus embryos. PLoS One. 2017 Apr 27;12(4):e0176479. doi: 10.1371/journal.pone.0176479. eCollection 2017.

CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder

Authors:
Wortmann SB, Ziętkiewicz S, Kousi M, Szklarczyk R, Haack TB, Gersting SW, Muntau AC, Rakovic A, Renkema GH, Rodenburg RJ, Strom TM, Meitinger T, Rubio-Gozalbo ME, Chrusciel E, Distelmaier F, Golzio C, Jansen JH, van Karnebeek C, Lillquist Y, Lücke T, Õunap K, Zordania R, Yaplito-Lee J, van Bokhoven H, Spelbrink JN, Vaz FM, Pras-Raves M, Ploski R, Pronicka E, Klein C, Willemsen MA, de Brouwer AP, Prokisch H, Katsanis N, Wevers RA.
Citation:
Am J Hum Genet. 2015 Feb 5;96(2):245-57. doi: 10.1016/j.ajhg.2014.12.013. Epub 2015 Jan 15
Epub:
Not Epub
Abstract:
We studied a group of individuals with elevated urinary excretion of 3-methylglutaconic acid, neutropenia that can develop into...
Link:
http://www.cell.com/ajhg/fulltext/S0002-9297(14)00519-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wortmann SB, Ziętkiewicz S, Kousi M, Szklarczyk R, Haack TB, Gersting SW, Muntau AC, Rakovic A, Renkema GH, Rodenburg RJ, Strom TM, Meitinger T, Rubio-Gozalbo ME, Chrusciel E, Distelmaier F, Golzio C, Jansen JH, van Karnebeek C, Lillquist Y, Lücke T, Õunap K, Zordania R, Yaplito-Lee J, van Bokhoven H, Spelbrink JN, Vaz FM, Pras-Raves M, Ploski R, Pronicka E, Klein C, Willemsen MA, de Brouwer AP, Prokisch H, Katsanis N, Wevers RA.. CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder. Am J Hum Genet. 2015 Feb 5;96(2):245-57. doi: 10.1016/j.ajhg.2014.12.013. Epub 2015 Jan 15.

Identification of target genes downstream of Semaphorin6A/PlexinA2 signaling in zebrafish

Authors:
Emerson SE, St Clair RM, Waldron AL, Bruno SR, Duong A, Driscoll HE, Ballif BA, McFarlane S, Ebert AM
Citation:
Dev Dyn. 2017 Apr 25. doi: 10.1002/dvdy.24512. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Semaphorin (Sema)/Plexin (Plxn) signaling is important for many aspects of neuronal development, however the...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24512/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Emerson SE, St Clair RM, Waldron AL, Bruno SR, Duong A, Driscoll HE, Ballif BA, McFarlane S, Ebert AM. Identification of target genes downstream of Semaphorin6A/PlexinA2 signaling in zebrafish. Dev Dyn. 2017 Apr 25. doi: 10.1002/dvdy.24512. [Epub ahead of print].

Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish

Authors:
Welch EL, Eno CC, Nair S, Lindeman RE, Pelegri F
Citation:
JoVE. 2017;122:e55213. doi:10.3791/55213
Epub:
Not Epub
Abstract:
Cellular events that take place during the earliest stages of animal embryonic development are driven by maternally derived...
Link:
https://www.jove.com/video/55213/functional-manipulation-maternal-gene-products-using-vitro-oocyte
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Welch EL, Eno CC, Nair S, Lindeman RE, Pelegri F. Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish. JoVE. 2017;122:e55213. doi:10.3791/55213.

Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity

Authors:
Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL
Citation:
Cell Res. 2017 Apr 21. doi: 10.1038/cr.2017.62. [Epub ahead of print]
Epub:
Yes
Abstract:
Vascular integrity helps maintain brain microenvironment homeostasis, which is critical for the normal development and function...
Link:
http://www.nature.com/cr/journal/vaop/ncurrent/full/cr201762a.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL. Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity. Cell Res. 2017 Apr 21. doi: 10.1038/cr.2017.62. [Epub ahead of print].

CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions

Authors:
Chrifi I, Louzao-Martinez L, Brandt M, van Dijk CGM, Burgisser P, Zhu C, Kros JM, Duncker DJ, Cheng C
Citation:
Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1098-1114. doi: 10.1161/ATVBAHA.116.308792. Epub 2017 Apr 20. PMID: 28428220
Epub:
Yes
Abstract:
Objective: Decrease in VE-cadherin adherens junctions reduces vascular stability, whereas disruption of adherens junctions is a...
Link:
https://www.ahajournals.org/doi/10.1161/ATVBAHA.116.308792
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chrifi I, Louzao-Martinez L, Brandt M, van Dijk CGM, Burgisser P, Zhu C, Kros JM, Duncker DJ, Cheng C. CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions. Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1098-1114. doi: 10.1161/ATVBAHA.116.308792. Epub 2017 Apr 20. PMID: 28428220.

Ultrasensitive Detection of MicroRNAs with Morpholino-Functionalized Nanochannel Biosensor

Authors:
Liao T, Li X, Tong Q, Zou K, Zhang H, Tang L, Sun Z, Zhang G-J
Citation:
Anal Chem. 2017;[Just accepted] doi:10.1021/acs.analchem.7b00487
Epub:
Yes
Abstract:
Here we demonstrate a phosphorodiamidate morpholino oligos (PMO)-functionlized nanochannel biosensor for label-free detection...
Link:
http://pubs.acs.org/doi/abs/10.1021/acs.analchem.7b00487
Citation Extract:
Liao T, Li X, Tong Q, Zou K, Zhang H, Tang L, Sun Z, Zhang G-J. Ultrasensitive Detection of MicroRNAs with Morpholino-Functionalized Nanochannel Biosensor. Anal Chem. 2017;[Just accepted] doi:10.1021/acs.analchem.7b00487.

Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation

Authors:
Rudigier LJ, Dame C, Scholz H, Kirschner KM
Citation:
PLoS ONE. 2017;12(4):e0176296. doi:10.1371/journal.pone.0176296
Epub:
Not Epub
Abstract:
Gonad morphogenesis relies on the correct spatiotemporal expression of a number of genes that together fulfill the...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176296
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse gonad explants
Citation Extract:
Rudigier LJ, Dame C, Scholz H, Kirschner KM. Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation. PLoS ONE. 2017;12(4):e0176296. doi:10.1371/journal.pone.0176296.

Pages