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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Systemic Antisense Therapeutics for Dystrophin and Myostatin Exon Splice Modulation Improve Muscle Pathology of Adult mdx Mice
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Citation:
Mol Ther Nucleic Acids. 2017 Mar 17;6:15-28. doi: 10.1016/j.omtn.2016.11.009 Epub:
Not Epub Abstract:
Antisense-mediated exon skipping is a promising approach for the treatment of Duchenne muscular dystrophy (DMD), a rare life-... Delivery Method:
peptide-linked Organism or Cell Type:
mouse mdx Citation Extract: Lu-Nguyen N, Malerba A, Popplewell L, Schnell F, Hanson G, Dickson G. Systemic Antisense Therapeutics for Dystrophin and Myostatin Exon Splice Modulation Improve Muscle Pathology of Adult mdx Mice. Mol Ther Nucleic Acids. 2017 Mar 17;6:15-28. doi: 10.1016/j.omtn.2016.11.009. |
Molecular physiology of the hypocalcemic action of fibroblast growth factor 23 in zebrafish (Danio rerio)
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Citation:
Endocrinology. 2017 Mar 1. doi: 10.1210/en.2016-1883. [Epub ahead of print] Epub:
Yes Abstract:
Fibroblast growth factor 23 (FGF23), a hormone required for phosphorus metabolism, was recently proposed to act on Ca2+ uptake... Organism or Cell Type:
zebrafish Citation Extract: Lin CH, Hu HJ, Hwang PP. Molecular physiology of the hypocalcemic action of fibroblast growth factor 23 in zebrafish (Danio rerio). Endocrinology. 2017 Mar 1. doi: 10.1210/en.2016-1883. [Epub ahead of print]. |
sall1 and sall4 repress pou5f3 family expression to allow neural patterning, differentiation, and morphogenesis in Xenopus laevis
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Citation:
Dev Biol. 2017 Mar 18. pii: S0012-1606(16)30754-0. doi: 10.1016/j.ydbio.2017.03.015. [Epub ahead of print] Epub:
Yes Abstract:
The embryonic precursor of the vertebrate central nervous system, the neural plate, is patterned along the anterior-posterior... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Exner CR, Kim AY, Mardjuki SM, Harland RM. sall1 and sall4 repress pou5f3 family expression to allow neural patterning, differentiation, and morphogenesis in Xenopus laevis. Dev Biol. 2017 Mar 18. pii: S0012-1606(16)30754-0. doi: 10.1016/j.ydbio.2017.03.015. [Epub ahead of print]. |
Discovery of Novel Determinants of Endothelial Lineage using Chimeric Heterokaryons
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Citation:
eLife. 2017; doi:10.7554/eLife.23588 Epub:
Not Epub Abstract:
We wish to identify determinants of endothelial lineage. Murine embryonic stem cells (mESC) were fused with human endothelial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wong WT, Matrone G, Tian XY, Tomoiaga SA, Au KF, Meng S, Yamazoe S, Sieveking D, Chen K, Burns DM, Chen JK, Blau HM, Cooke JP. Discovery of Novel Determinants of Endothelial Lineage using Chimeric Heterokaryons. eLife. 2017; doi:10.7554/eLife.23588. |
Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos
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Citation:
Sci Rep. 2017;7:45058 doi:10.1038/srep45058 Epub:
Not Epub Abstract:
Epithelia represent a unique situation where polarized cells must maintain sufficiently strong cell-cell contacts to guarantee... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Herbomel G, Hatte G, Roul J, Padilla-Parra S, Tassan J-P, Tramier M. Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos. Sci Rep. 2017;7:45058 doi:10.1038/srep45058. |
Paxillin Genes and Actomyosin Contractility Regulate Myotome Morphogenesis in Zebrafish
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Citation:
Dev Biol. 2017 Mar 14. pii: S0012-1606(16)30694-7. doi: 10.1016/j.ydbio.2017.03.012. [Epub ahead of print] Epub:
Yes Abstract:
Paxillin (Pxn) is a key adapter protein and signaling regulator at sites of cell-extracellular matrix (ECM) adhesion. Here, we... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jacob AE, Amack JD, Turner CE. Paxillin Genes and Actomyosin Contractility Regulate Myotome Morphogenesis in Zebrafish. Dev Biol. 2017 Mar 14. pii: S0012-1606(16)30694-7. doi: 10.1016/j.ydbio.2017.03.012. [Epub ahead of print]. |
Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine
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Citation:
J Clin Invest. 2017;[Epub ahead of print] doi:10.1172/JCI88760 Epub:
Yes Abstract:
Extensive 3′ alternative splicing of the mu opioid receptor gene OPRM1 creates multiple C-terminal splice variants. However,... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse Citation Extract: Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, Pan Y-X. Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine. J Clin Invest. 2017;[Epub ahead of print] doi:10.1172/JCI88760. |
Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes
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Citation:
Oncotarget. 2017 Feb 4. doi: 10.18632/oncotarget.15097. [Epub ahead of print] Epub:
Yes Abstract:
Mammalian oocyte meiotic maturation is the precondition of early embryo development. Lots of microtubules (MT)-associated... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Lu A, Zhou CJ, Wang DH, Han Z, Kong XW, Ma YZ, Yun ZZ, Liang CG. Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes. Oncotarget. 2017 Feb 4. doi: 10.18632/oncotarget.15097. [Epub ahead of print]. |
Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy
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Citation:
JCI Insight. 2016 Jul 21;1(11):e87908 Epub:
Not Epub Abstract:
The autosomal recessive neuromuscular disease spinal muscular atrophy (SMA) is caused by loss of survival motor neuron (SMN)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Powis RA, Karyka E, Boyd P, Côme J, Jones RA, Zheng Y, Szunyogova E, Groen EJ, Hunter G, Thomson D, Wishart TM, Becker CG, Parson SH, Martinat C, Azzouz M, Gillingwater TH. Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy. JCI Insight. 2016 Jul 21;1(11):e87908. |
c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor
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Citation:
J Immunol. 2016 Sep 1;197(5):1650-62. doi: 10.4049/jimmunol.1600104 Epub:
Not Epub Abstract:
The enhanced expression of T cell Ig and mucin protein-3 (TIM-3) on tumor-associated dendritic cells (DCs) attenuates antitumor... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice (B6 and BALB/c) Citation Extract: Gujar R, Maurya N, Yadav V, Gupta M, Arora S, Khatri N, Sen P. c-Src Suppresses Dendritic Cell Antitumor Activity via T Cell Ig and Mucin Protein-3 Receptor. J Immunol. 2016 Sep 1;197(5):1650-62. doi: 10.4049/jimmunol.1600104. |