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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
A truncating mutation in CEP55 is the likely cause of MARCH, a novel syndrome affecting neuronal mitosis
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Citation:
J Med Genet. 2017;[Epub ahead of print] doi:10.1136/jmedgenet-2016-104296 Epub:
Yes Abstract:
Background Hydranencephaly is a congenital anomaly leading to replacement of the cerebral hemispheres with a fluid-filled cyst... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Frosk P, Arts HH, Philippe J, Gunn CS, Brown EL, Chodirker B, Simard L, Majewski J, Fahiminiya S, Russell C, Liu YP, FORGE Canada Consortium, Canadian Rare Diseases: Models & Mechanisms Network, Hegele R, Katsanis N, Goerz C, Del Bigio MR, Davis EE. A truncating mutation in CEP55 is the likely cause of MARCH, a novel syndrome affecting neuronal mitosis. J Med Genet. 2017;[Epub ahead of print] doi:10.1136/jmedgenet-2016-104296. |
Uncoupling of neurogenesis and differentiation during retinal development
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Citation:
EMBO J. 2017 Mar 3. pii: e201694230. doi: 10.15252/embj.201694230. [Epub ahead of print] Epub:
Not Epub Abstract:
Conventionally, neuronal development is regarded to follow a stereotypic sequence of neurogenesis, migration, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Engerer P, Suzuki SC, Yoshimatsu T, Chapouton P, Obeng N, Odermatt B, Williams PR, Misgeld T, Godinho L. Uncoupling of neurogenesis and differentiation during retinal development. EMBO J. 2017 Mar 3. pii: e201694230. doi: 10.15252/embj.201694230. [Epub ahead of print]. |
Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation
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Citation:
Development. 2017;144:1518-30. doi: 10.1242/dev.137315 Epub:
Not Epub Abstract:
Folate supplementation prevents up to 70% of neural tube defects (NTDs), which result from a failure of neural tube closure... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Balashova OA, Visina O, Borodinsky LN. Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation. Development. 2017;144:1518-30. doi: 10.1242/dev.137315. |
Antisense Oligonucleotides Used to Target the DUX4 mRNA as Therapeutic Approaches in FaciosScapuloHumeral Muscular Dystrophy (FSHD)
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Citation:
Genes. 2017;8(3):93 doi:10.3390/genes8030093 Epub:
Not Epub Abstract:
FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent hereditary myopathies and is generally characterized... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse Citation Extract: Ansseau E, Vanderplanck C, Wauters A, Harper SQ, Coppée F, Belayew A. Antisense Oligonucleotides Used to Target the DUX4 mRNA as Therapeutic Approaches in FaciosScapuloHumeral Muscular Dystrophy (FSHD). Genes. 2017;8(3):93 doi:10.3390/genes8030093. |
The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues
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Citation:
npj Regen Med. 2017;2:4. doi:10.1038/s41536-017-0008-1 Epub:
Not Epub Abstract:
Regenerative medicine holds substantial promise for repairing or replacing tissues and organs damaged by disease, injury, and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Smith AM, Maguire-Nguyen KK, Rando TA, Zasloff MA, Strange KB, Yin VP. The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues. npj Regen Med. 2017;2:4. doi:10.1038/s41536-017-0008-1. |
The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors
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Citation:
Nat Comm. 2017;8:14640 doi:10.1038/ncomms14640 Epub:
Not Epub Abstract:
Vasculogenic defects of great vessels (GVs) are a major cause of congenital cardiovascular diseases. However, genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meng Z-Z, Liu W, Xia Y, Yin H-M, Zhang C-Y, Su D, Yan L-F, Gu A-H, Zhou Y. The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors. Nat Comm. 2017;8:14640 doi:10.1038/ncomms14640. |
Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors
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Citation:
PLoS One. 2017 Mar 2;12(3):e0172947. doi: 10.1371/journal.pone.0172947 Epub:
Not Epub Abstract:
The development of functional peripheral ganglia requires a balance of specification of both neuronal and glial components. In... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Delfino-Machín M, Madelaine R, Busolin G, Nikaido M, Colanesi S, Camargo-Sosa K, Law EW, Toppo S, Blader P, Tiso N, Kelsh RN. Sox10 contributes to the balance of fate choice in dorsal root ganglion progenitors. PLoS One. 2017 Mar 2;12(3):e0172947. doi: 10.1371/journal.pone.0172947. |
Using Morpholinos to Control Gene Expression
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Citation:
Curr Protoc Nucleic Acid Chem. 2017 Mar 2;68:4.30.1-4.30.29. doi: 10.1002/cpnc.21 Epub:
Not Epub Abstract:
Morpholino oligonucleotides are stable, uncharged, water-soluble molecules used to block complementary sequences of RNA,... Citation Extract: Moulton JD. Using Morpholinos to Control Gene Expression. Curr Protoc Nucleic Acid Chem. 2017 Mar 2;68:4.30.1-4.30.29. doi: 10.1002/cpnc.21. |
tomm22 knockdown-mediated hepatocyte damages elicit both the formation of hybrid hepatocytes and biliary conversion to hepatocytes in zebrafish larvae
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Citation:
Gene Expr. 2017 Mar 1. doi: 10.3727/105221617X695195. [Epub ahead of print] Epub:
Yes Abstract:
The liver has a highly regenerative capacity. In the normal liver, hepatocytes proliferate to restore lost liver mass. However... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu J, Choi TY, Shin D. tomm22 knockdown-mediated hepatocyte damages elicit both the formation of hybrid hepatocytes and biliary conversion to hepatocytes in zebrafish larvae. Gene Expr. 2017 Mar 1. doi: 10.3727/105221617X695195. [Epub ahead of print]. |
Myeloid and erythroid hematopoietic transcription factor expression decline after knockdown of lmna genes in zebrafish embryos
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Citation:
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25;45(6):620-625. Chinese Epub:
Not Epub Abstract:
Objective: To investigate the effect of lmna gene down-regulation on early hematopoietic development of zebrafish. Methods:... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hou S, Wang Z, Wang J, He Z, Shu L. Myeloid and erythroid hematopoietic transcription factor expression decline after knockdown of lmna genes in zebrafish embryos. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 May 25;45(6):620-625. Chinese. |