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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Vegfa Impacts Early Myocardium Development in Zebrafish
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Citation:
Int J Mol Sci. 2017;18(2):444 doi:10.3390/ijms18020444 Epub:
Not Epub Abstract:
Vascular endothelial growth factor A (Vegfa) signaling regulates cardiovascular development. However, the cellular mechanisms... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu D, Fang Y, Gao K, Shen J, Zhong TP, Li F. Vegfa Impacts Early Myocardium Development in Zebrafish. Int J Mol Sci. 2017;18(2):444 doi:10.3390/ijms18020444. |
Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation
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Citation:
PLoS Genet. 2017;13(2):e1006564. doi:10.1371/journal.pgen.1006564 Epub:
Not Epub Abstract:
Cell proliferation has generally been considered dispensable for anteroposterior extension of embryonic axis during vertebrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu Y, Sepich DS, Solnica-Krezel L. Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. PLoS Genet. 2017;13(2):e1006564. doi:10.1371/journal.pgen.1006564. |
A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome
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Citation:
Am J Med Genet A. 2017 Mar;173(3):712-715. doi: 10.1002/ajmg.a.37621 Epub:
Not Epub Abstract:
NDST1 encodes an enzyme involved in the first steps in the synthesis of heparan sulfate chains, proteoglycans that are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Armstrong L, Tarailo-Graovac M, Sinclair G, Seath KI, Wasserman WW, Ross CJ, van Karnebeek CD. A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome. Am J Med Genet A. 2017 Mar;173(3):712-715. doi: 10.1002/ajmg.a.37621. |
The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
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Citation:
J Vis Exp. 2017;120:e55113. doi:10.3791/55113 Epub:
Not Epub Abstract:
Remarkably few cell-to-cell signal transduction pathways are necessary during embryonic development to generate the large... Organism or Cell Type:
sea urchin Citation Extract: Range RC, Martinez-Bartolomé M, Burr SD. The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions. J Vis Exp. 2017;120:e55113. doi:10.3791/55113. |
Hyaluronic acid synthesis is required for zebrafish tail fin regeneration
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Citation:
PLoS One. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898 Epub:
Not Epub Abstract:
Using genome-wide transcriptional profiling and whole-mount expression analyses of zebrafish larvae, we have identified... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ouyang X, Panetta NJ, Talbott MD, Payumo AY, Halluin C, Longaker MT, Chen JK. Hyaluronic acid synthesis is required for zebrafish tail fin regeneration. PLoS One. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898. |
The enteric nervous system promotes intestinal health by constraining microbiota composition
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Citation:
PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689 Epub:
Not Epub Abstract:
Sustaining a balanced intestinal microbial community is critical for maintaining intestinal health and preventing chronic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rolig AS, Mittge EK, Ganz J, Troll JV, Melancon E, Wiles TJ, Alligood K, Stephens WZ, Eisen JS, Guillemin K. The enteric nervous system promotes intestinal health by constraining microbiota composition. PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689. |
Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency
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Citation:
J Allergy Clin Immunol. 2017 May;139(5):1688-1692.e10. doi: 10.1016/j.jaci.2017.02.002. Epub 2017 Feb 17. PMID: 28216435; PMCID: PMC7126384 Epub:
Yes Abstract:
An adult with hypomorphic ZAP-70 deficiency due to de novo donor splice site mutation manifested autoimmunity, infections... Citation Extract: Gavino C, Landekic M, Zeng J, Wu N, Jung S, Zhong MC, Cohen-Blanchet A, Langelier M, Neyret O, Lejtenyi D, Rochefort C, Cotton-Montpetit J, McCusker C, Mazer B, Veillette A, Vinh DC. Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency. J Allergy Clin Immunol. 2017 May;139(5):1688-1692.e10. doi: 10.1016/j.jaci.2017.02.002. Epub 2017 Feb 17. PMID: 28216435; PMCID: PMC7126384. |
Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish
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Citation:
bioRxiv. 2017. doi:10.1101/108779 Epub:
Yes Abstract:
Notch signaling plays an essential role in the proliferation, differentiation and cell fate determination of various tissues,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Veen M, van Pelt J, Mans LA, Moolenaar WH, Haramis A-PG. Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish. bioRxiv. 2017. doi:10.1101/108779. |
Mechanical stretch triggers rapid epithelial cell division through Piezo1
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Citation:
Nature. 2017;543:118–121. doi:10.1038/nature21407 Epub:
Yes Abstract:
Despite acting as a barrier for the organs they encase, epithelial cells turn over at some of the fastest rates in the body.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gudipaty SA, Lindblom J, Loftus PD, Redd MJ, Edes K, Davey CF, Krishnegowda V, Rosenblatt J. Mechanical stretch triggers rapid epithelial cell division through Piezo1. Nature. 2017;543:118–121. doi:10.1038/nature21407. |
The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection
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Citation:
Sci Signal. 2017;10(466):eaaf5185. doi:10.1126/scisignal.aaf5185 Epub:
Not Epub Abstract:
Effective recognition of viral components and the subsequent stimulation of the production of type I interferons (IFNs) is... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
BALB/c mice Citation Extract: Hazra B, Kumawat KL, Basu A. The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection. Sci Signal. 2017;10(466):eaaf5185. doi:10.1126/scisignal.aaf5185. |