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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

USP40 gene knockdown disrupts glomerular permeability in zebrafish

Authors:
Takagi H, Nishibori Y, Katayama K, Katada T, Takahashi S, Kiuchi Z, Takahashi SI, Kamei H, Kawakami H, Akimoto Y, Kudo A, Asanuma K, Takematsu H, Yan K
Citation:
Am J Physiol Renal Physiol. 2017 Feb 1:ajprenal.00197.2016. doi: 10.1152/ajprenal.00197.2016. [Epub ahead of print]
Epub:
Yes
Abstract:
Unbiased transcriptome profiling and functional genomics approaches have identified ubiquitin specific protease 40 (USP40) as a...
Link:
http://ajprenal.physiology.org/content/early/2017/01/25/ajprenal.00197.2016
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Takagi H, Nishibori Y, Katayama K, Katada T, Takahashi S, Kiuchi Z, Takahashi SI, Kamei H, Kawakami H, Akimoto Y, Kudo A, Asanuma K, Takematsu H, Yan K. USP40 gene knockdown disrupts glomerular permeability in zebrafish. Am J Physiol Renal Physiol. 2017 Feb 1:ajprenal.00197.2016. doi: 10.1152/ajprenal.00197.2016. [Epub ahead of print].

Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development

Authors:
Bower NI, Vogrin AJ, Le Guen L, Chen H, Stacker SA, Achen MG, Hogan BM
Citation:
Development. 2017 Feb 1;144(3):507-518. doi: 10.1242/dev.146969
Epub:
Not Epub
Abstract:
Vascular endothelial growth factors (VEGFs) control angiogenesis and lymphangiogenesis during development and in pathological...
Link:
http://dev.biologists.org/content/144/3/507
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bower NI, Vogrin AJ, Le Guen L, Chen H, Stacker SA, Achen MG, Hogan BM. Vegfd modulates both angiogenesis and lymphangiogenesis during zebrafish embryonic development. Development. 2017 Feb 1;144(3):507-518. doi: 10.1242/dev.146969.

miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA

Authors:
Bellon A, Iyer A, Bridi S, Lee FC, Ovando-Vázquez C, Corradi E, Longhi S, Roccuzzo M, Strohbuecker S, Naik S, Sarkies P, Miska E, Abreu-Goodger C, Holt CE, Baudet ML
Citation:
Cell Rep. 2017 Jan 31;18(5):1171-1186. doi: 10.1016/j.celrep.2016.12.093
Epub:
Not Epub
Abstract:
During brain wiring, cue-induced axon behaviors such as directional steering and branching are aided by localized mRNA...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30003-7
Delivery Method:
microinjection, electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bellon A, Iyer A, Bridi S, Lee FC, Ovando-Vázquez C, Corradi E, Longhi S, Roccuzzo M, Strohbuecker S, Naik S, Sarkies P, Miska E, Abreu-Goodger C, Holt CE, Baudet ML. miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA. Cell Rep. 2017 Jan 31;18(5):1171-1186. doi: 10.1016/j.celrep.2016.12.093.

Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts

Authors:
Straubinger J, Boldt K, Kuret A, Deng L, Krattenmacher D, Bork N, Desch M, Feil R, Feil S, Nemer M, Ueffing M, Ruth P, Just S, Lukowski R
Citation:
FASEB J. 2017 Jan 30. pii: fj.201601186. doi: 10.1096/fj.201601186. [Epub ahead of print]
Epub:
Yes
Abstract:
LIM domain proteins have been identified as essential modulators of cardiac biology and pathology; however, it is unclear which...
Link:
http://www.fasebj.org/content/early/2017/01/30/fj.201601186.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Straubinger J, Boldt K, Kuret A, Deng L, Krattenmacher D, Bork N, Desch M, Feil R, Feil S, Nemer M, Ueffing M, Ruth P, Just S, Lukowski R. Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts. FASEB J. 2017 Jan 30. pii: fj.201601186. doi: 10.1096/fj.201601186. [Epub ahead of print].

Inhibition of Pseudomonas aeruginosa by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers

Authors:
Howard JJ, Sturge CR, Moustafa DA, Daly SM, Marshall-Batty KR, Felder CF, Zamora D, Yabe-Gill M, Labandeira-Rey M, Bailey SM, Wong M, Goldberg JB, Geller BL, Greenberg DE
Citation:
Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.01938-16. doi: 10.1128/AAC.01938-16. [Epub ahead of print]
Epub:
Yes
Abstract:
Pseudomonas aeruginosa is a highly virulent, multidrug-resistant pathogen that causes significant morbidity and mortality in...
Link:
http://aac.asm.org/content/early/2017/01/24/AAC.01938-16.abstract
Delivery Method:
peptide-linked
Organism or Cell Type:
Pseudomonas aeruginosa
Citation Extract:
Howard JJ, Sturge CR, Moustafa DA, Daly SM, Marshall-Batty KR, Felder CF, Zamora D, Yabe-Gill M, Labandeira-Rey M, Bailey SM, Wong M, Goldberg JB, Geller BL, Greenberg DE. Inhibition of Pseudomonas aeruginosa by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers. Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.01938-16. doi: 10.1128/AAC.01938-16. [Epub ahead of print].

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice

Authors:
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, AB Robertson AAB, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Smyth MJ, Cooper MA, Gambin Y, Francois M
Citation:
eLife. 2017;6:e21221 doi:10.7554/eLife.21221
Epub:
Not Epub
Abstract:
Pharmacological targeting of transcription factors holds great promise for the development of new therapeutics, but strategies...
Link:
https://elifesciences.org/content/6/e21221
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, AB Robertson AAB, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Smyth MJ, Cooper MA, Gambin Y, Francois M. Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice. eLife. 2017;6:e21221 doi:10.7554/eLife.21221.

Identification of Mutant Genes and Introgressed Tiger Salamander DNA in the Laboratory Axolotl, Ambystoma mexicanum

Authors:
Woodcock MR, Vaughn-Wolfe J, Elias A, Kump DK, Kendall KD, Timoshevskaya N, Timoshevskiy V, Perry DW, Smith JJ, Spiewak JE, Parichy DM, Voss SR
Citation:
Sci Rep. 2017 Dec;7(1):6. doi: 10.1038/s41598-017-00059-1
Epub:
Not Epub
Abstract:
The molecular genetic toolkit of the Mexican axolotl, a classic model organism, has matured to the point where it is now...
Link:
http://www.nature.com/articles/s41598-017-00059-1
Delivery Method:
microinjection
Organism or Cell Type:
Ambystoma mexicanum (Axolotl)
Citation Extract:
Woodcock MR, Vaughn-Wolfe J, Elias A, Kump DK, Kendall KD, Timoshevskaya N, Timoshevskiy V, Perry DW, Smith JJ, Spiewak JE, Parichy DM, Voss SR. Identification of Mutant Genes and Introgressed Tiger Salamander DNA in the Laboratory Axolotl, Ambystoma mexicanum. Sci Rep. 2017 Dec;7(1):6. doi: 10.1038/s41598-017-00059-1.

Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity

Authors:
He X, Zhang W, Yan C, Nie F, Li C, Liu X, Fei C, Li D, Song X, Jia Y, Zeng R, Wu D, Pan W, Hao X, Li L
Citation:
Cell Disc. 2017;3:17003. doi:10.1038/celldisc.2017.3
Epub:
Not Epub
Abstract:
Wnt/β-catenin signaling regulates multiple biological processes and aberration of this pathway is frequently observed in human...
Link:
http://www.nature.com/articles/celldisc20173
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He X, Zhang W, Yan C, Nie F, Li C, Liu X, Fei C, Li D, Song X, Jia Y, Zeng R, Wu D, Pan W, Hao X, Li L. Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity. Cell Disc. 2017;3:17003. doi:10.1038/celldisc.2017.3.

Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis

Authors:
Riessland M, Kaczmarek A, Schneider S, Swoboda KJ, Löhr H, Bradler C, Grysko V, Dimitriadi M, Hosseinibarkooie S, Torres-Benito L, Peters M, Upadhyay A, Biglari N, Kröber S, Hölker I, Garbes L, Gilissen C, Hoischen A, Nürnberg G, Nürnberg P, Walter M, Rigo F, Bennett CF, Kye MJ, Hart AC, Hammerschmidt M, Kloppenburg P, Wirth B
Citation:
Am J Hum Genet. 2017 Jan 20. pii: S0002-9297(17)30005-8. doi: 10.1016/j.ajhg.2017.01.005. [Epub ahead of print]
Epub:
Yes
Abstract:
Homozygous SMN1 loss causes spinal muscular atrophy (SMA), the most common lethal genetic childhood motor neuron disease. SMN1...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(17)30005-8
Organism or Cell Type:
zebrafish
Citation Extract:
Riessland M, Kaczmarek A, Schneider S, Swoboda KJ, Löhr H, Bradler C, Grysko V, Dimitriadi M, Hosseinibarkooie S, Torres-Benito L, Peters M, Upadhyay A, Biglari N, Kröber S, Hölker I, Garbes L, Gilissen C, Hoischen A, Nürnberg G, Nürnberg P, Walter M, Rigo F, Bennett CF, Kye MJ, Hart AC, Hammerschmidt M, Kloppenburg P, Wirth B. Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. Am J Hum Genet. 2017 Jan 20. pii: S0002-9297(17)30005-8. doi: 10.1016/j.ajhg.2017.01.005. [Epub ahead of print].

The translational blocking of α5 and α6 integrin subunits affects migration and invasion, and increases sensitivity to carboplatin of SKOV-3 ovarian cancer cell line

Authors:
Villegas-Pineda JC, Toledo-Leyva A, Osorio-Trujillo JC, Hernández-Ramírez VI, Talamás-Rohana P
Citation:
Exp Cell Res. 2017 Jan 25. pii: S0014-4827(17)30019-8. doi: 10.1016/j.yexcr.2017.01.010. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Epithelial ovarian cancer is the most lethal gynecologic malignancy. Integrins, overexpressed in cancer, are involved in...
Link:
http://www.sciencedirect.com/science/article/pii/S0014482717300198
Organism or Cell Type:
cell culture: SKOV-3 ovarian cancer
Citation Extract:
Villegas-Pineda JC, Toledo-Leyva A, Osorio-Trujillo JC, Hernández-Ramírez VI, Talamás-Rohana P. The translational blocking of α5 and α6 integrin subunits affects migration and invasion, and increases sensitivity to carboplatin of SKOV-3 ovarian cancer cell line. Exp Cell Res. 2017 Jan 25. pii: S0014-4827(17)30019-8. doi: 10.1016/j.yexcr.2017.01.010. [Epub ahead of print].

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