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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy

Authors:
Shabanpoor F, Hammond SM, Abendroth F, Hazell G, Wood MJ, Gait MJ
Citation:
Nucleic Acid Ther. 2017 Jan 24. doi: 10.1089/nat.2016.0652. [Epub ahead of print]
Epub:
Yes
Abstract:
Splice-switching antisense oligonucleotides are emerging treatments for neuromuscular diseases, with several splice-switching...
Delivery Method:
peptide-linked
Organism or Cell Type:
mouse
Citation Extract:
Shabanpoor F, Hammond SM, Abendroth F, Hazell G, Wood MJ, Gait MJ. Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy. Nucleic Acid Ther. 2017 Jan 24. doi: 10.1089/nat.2016.0652. [Epub ahead of print].

FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos

Authors:
Yasuo H, Hudson C
Citation:
Dev Biol. 2007 Feb 1;302(1):92-103
Epub:
Not Epub
Abstract:
Fibroblast growth factor (FGF) signalling has been implicated in the generation of mesoderm and neural fates in chordate...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Yasuo H, Hudson C. FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos. Dev Biol. 2007 Feb 1;302(1):92-103.

Isl2b regulates anterior second heart field development in zebrafish

Authors:
Witzel HR, Cheedipudi S, Gao R, Stainier DY, Dobreva GD
Citation:
Sci Rep. 2017 Jan 20;7:41043. doi: 10.1038/srep41043
Epub:
Not Epub
Abstract:
After initial formation, the heart tube grows by addition of second heart field progenitor cells to its poles. The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Witzel HR, Cheedipudi S, Gao R, Stainier DY, Dobreva GD. Isl2b regulates anterior second heart field development in zebrafish. Sci Rep. 2017 Jan 20;7:41043. doi: 10.1038/srep41043.

Excessive activation of ionotropic glutamate receptors induces apoptotic hair-cell death independent of afferent and efferent innervation

Authors:
Sheets L
Citation:
Sci Rep. 2017 Jan 23;7:41102. doi: 10.1038/srep41102
Epub:
Not Epub
Abstract:
Accumulation of excess glutamate plays a central role in eliciting the pathological events that follow intensely loud noise...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sheets L . Excessive activation of ionotropic glutamate receptors induces apoptotic hair-cell death independent of afferent and efferent innervation. Sci Rep. 2017 Jan 23;7:41102. doi: 10.1038/srep41102.

Suppression of Neu1 sialidase delays the absorption of yolk sac in medaka (Oryzias latipes) accompanied with the accumulation of α2-3 sialo-glycoproteins

Authors:
Ryuzono S, Takase R, Kamada Y, Ikenaga T, Chigwechokha PK, Komatsu M, Shiozaki K
Citation:
Biochimie. 2017 Jan 19. pii: S0300-9084(17)30013-5. doi: 10.1016/j.biochi.2017.01.008. [Epub ahead of print]
Epub:
Yes
Abstract:
Sialidase catalyzes the removal of sialic acids from glycoconjugates. Recently, medaka sialidase Neu1 has been cloned and its...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Ryuzono S, Takase R, Kamada Y, Ikenaga T, Chigwechokha PK, Komatsu M, Shiozaki K. Suppression of Neu1 sialidase delays the absorption of yolk sac in medaka (Oryzias latipes) accompanied with the accumulation of α2-3 sialo-glycoproteins. Biochimie. 2017 Jan 19. pii: S0300-9084(17)30013-5. doi: 10.1016/j.biochi.2017.01.008. [Epub ahead of print].

Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression

Authors:
Quigley IK, Kintner C
Citation:
PLoS Genet. 2017 Jan 19;13(1):e1006538. doi: 10.1371/journal.pgen.1006538
Epub:
Not Epub
Abstract:
Cooperative transcription factor binding at cis-regulatory sites in the genome drives robust eukaryotic gene expression, and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Quigley IK, Kintner C. Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression. PLoS Genet. 2017 Jan 19;13(1):e1006538. doi: 10.1371/journal.pgen.1006538.

Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly

Authors:
Bloomekatz J, Singh R, Prall OW, Dunn AC, Vaughan M, Loo CS, Harvey RP, Yelon D
Citation:
Elife. 2017 Jan 18;6. pii: e21172. doi: 10.7554/eLife.21172. [Epub ahead of print]
Epub:
Yes
Abstract:
Communication between neighboring tissues plays a central role in guiding organ morphogenesis. During heart tube assembly,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bloomekatz J, Singh R, Prall OW, Dunn AC, Vaughan M, Loo CS, Harvey RP, Yelon D. Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly. Elife. 2017 Jan 18;6. pii: e21172. doi: 10.7554/eLife.21172. [Epub ahead of print].

The Nedd4 binding protein 3 is required for anterior neural development in Xenopus laevis

Authors:
Kiem LM, Dietmann P, Linnemann A, Schmeisser MJ, Kühl SJ
Citation:
Dev Biol. 2017 Jan 16. pii: S0012-1606(16)30546-2. doi: 10.1016/j.ydbio.2017.01.009. [Epub ahead of print]
Epub:
Yes
Abstract:
The Fezzin family member Nedd4-binding protein 3 (N4BP3) is known to regulate axonal and dendritic branching. Here, we show...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kiem LM, Dietmann P, Linnemann A, Schmeisser MJ, Kühl SJ. The Nedd4 binding protein 3 is required for anterior neural development in Xenopus laevis. Dev Biol. 2017 Jan 16. pii: S0012-1606(16)30546-2. doi: 10.1016/j.ydbio.2017.01.009. [Epub ahead of print].

Nkx2.5 regulates Endothelin Converting Enzyme-1 during pharyngeal arch patterning

Authors:
Iklé JM, Tavares AL, King M, Ding H, Colombo S, Firulli BA, Fiulli AB, Targoff KL, Yelon D, Clouthier DE
Citation:
Genesis. 2017 Jan 20. doi: 10.1002/dvg.23021. [Epub ahead of print]
Epub:
Yes
Abstract:
In gnathostomes, dorsoventral (D-V) patterning of neural crest cells (NCC) within the pharyngeal arches is crucial for the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iklé JM, Tavares AL, King M, Ding H, Colombo S, Firulli BA, Fiulli AB, Targoff KL, Yelon D, Clouthier DE. Nkx2.5 regulates Endothelin Converting Enzyme-1 during pharyngeal arch patterning. Genesis. 2017 Jan 20. doi: 10.1002/dvg.23021. [Epub ahead of print].

ETS transcription factors Etv2 and Fli1b are required for tumor angiogenesis

Authors:
Baltrunaite K, Craig MP, Palencia Desai S, Chaturvedi P, Pandey RN, Hegde RS, Sumanas S
Citation:
Angiogenesis. 2017 Jan 20. doi: 10.1007/s10456-017-9539-8. [Epub ahead of print]
Epub:
Yes
Abstract:
ETS transcription factor ETV2/Etsrp functions as a key regulator of embryonic vascular development in multiple vertebrates....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baltrunaite K, Craig MP, Palencia Desai S, Chaturvedi P, Pandey RN, Hegde RS, Sumanas S. ETS transcription factors Etv2 and Fli1b are required for tumor angiogenesis. Angiogenesis. 2017 Jan 20. doi: 10.1007/s10456-017-9539-8. [Epub ahead of print].

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