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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish

Authors:
Chiba A, Watanabe-Takano H, Terai K, Fukui H, Miyazaki T, Uemura M, Hashimoto H, Hibi M, Fukuhara S, Mochizuki N
Citation:
Development. 2016 Dec 19. pii: dev.143354. [Epub ahead of print]
Epub:
Yes
Abstract:
The heart is an endocrine organ, because cardiomyocytes (CMs) secrete natriuretic peptide (NP) hormones. Since the discovery of...
Link:
http://dev.biologists.org/content/early/2016/12/17/dev.143354.long
Organism or Cell Type:
zebrafish
Citation Extract:
Chiba A, Watanabe-Takano H, Terai K, Fukui H, Miyazaki T, Uemura M, Hashimoto H, Hibi M, Fukuhara S, Mochizuki N. Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish. Development. 2016 Dec 19. pii: dev.143354. [Epub ahead of print].

Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells

Authors:
Zhang L, Fang Y, Yang J, Kopeček J
Citation:
J Control Release. 2016 Dec 23. pii: S0168-3659(16)31273-1. doi: 10.1016/j.jconrel.2016.12.025. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Recently, we developed a new paradigm in macromolecular therapeutics that avoids the use of low molecular weight drugs. The...
Link:
http://www.sciencedirect.com/science/article/pii/S0168365916312731
Organism or Cell Type:
cell culture: Raji B cells
Citation Extract:
Zhang L, Fang Y, Yang J, Kopeček J. Drug-free macromolecular therapeutics: Impact of structure on induction of apoptosis in Raji B cells. J Control Release. 2016 Dec 23. pii: S0168-3659(16)31273-1. doi: 10.1016/j.jconrel.2016.12.025. [Epub ahead of print].

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

Authors:
van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, Lange L, Floyd JS, Ghanbari M, Zonderman AB, Jukema JW, Hofman A, van Duijn CM, Desch KC, Saba Y, Ozel AB, Snively BM, Wu JY, Schmidt R, Fornage M, Klein RJ, Fox CS, Matsuda K, Kamatani N, Wild PS, Stott DJ, Ford I, Slagboom PE, Yang J, Chu AY, Lambert AJ, Uitterlinden AG, Franco OH, Hofer E, Ginsburg D, Hu B, Keating B, Schick UM, Brody JA, Li JZ, Chen Z, Zeller T, <authors deleted - database limit> Yang Q, Psaty BM, Boerwinkle E, Becker LC, Mook-Kanamori DO, Wilson JG, Gudnason V, O'Donnell CJ, Dehghan A, Cupples LA, Nalls MA, Morris AP, Okada Y, Reiner AP, Zon LI, Ganesh SK
Citation:
Am J Hum Genet. 2016 Dec 19. pii: S0002-9297(16)30520-1. doi: 10.1016/j.ajhg.2016.11.016. [Epub ahead of print]
Epub:
Yes
Abstract:
Genome-wide association studies (GWASs) have identified loci for erythrocyte traits in primarily European ancestry populations...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(16)30520-1
Organism or Cell Type:
zebrafish
Citation Extract:
van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, Lange L, Floyd JS, Ghanbari M, Zonderman AB, Jukema JW, Hofman A, van Duijn CM, Desch KC, Saba Y, Ozel AB, Snively BM, Wu JY, Schmidt R, Fornage M, Klein RJ, Fox CS, Matsuda K, Kamatani N, Wild PS, Stott DJ, Ford I, Slagboom PE, Yang J, Chu AY, Lambert AJ, Uitterlinden AG, Franco OH, Hofer E, Ginsburg D, Hu B, Keating B, Schick UM, Brody JA, Li JZ, Chen Z, Zeller T, <authors deleted - database limit> Yang Q, Psaty BM, Boerwinkle E, Becker LC, Mook-Kanamori DO, Wilson JG, Gudnason V, O'Donnell CJ, Dehghan A, Cupples LA, Nalls MA, Morris AP, Okada Y, Reiner AP, Zon LI, Ganesh SK. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Am J Hum Genet. 2016 Dec 19. pii: S0002-9297(16)30520-1. doi: 10.1016/j.ajhg.2016.11.016. [Epub ahead of print].

SLC44A4 Mutation Causes Autosomal Dominant Hereditary Postlingual Non-syndromic Mid-frequency Hearing loss

Authors:
Ma Z, Xia W, Liu F, Ma J, Sun S, Zhang J, Jiang N, Wang X, Hu J, Ma D
Citation:
Hum Mol Genet. 2016 Dec 23. pii: ddw394. doi: 10.1093/hmg/ddw394. [Epub ahead of print]
Epub:
Yes
Abstract:
Clinical, genetic, and functional investigations were performed to identify the causative mutation in a distinctive Chinese...
Link:
http://hmg.oxfordjournals.org/content/early/2016/12/22/hmg.ddw394.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Ma Z, Xia W, Liu F, Ma J, Sun S, Zhang J, Jiang N, Wang X, Hu J, Ma D. SLC44A4 Mutation Causes Autosomal Dominant Hereditary Postlingual Non-syndromic Mid-frequency Hearing loss. Hum Mol Genet. 2016 Dec 23. pii: ddw394. doi: 10.1093/hmg/ddw394. [Epub ahead of print].

FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy

Authors:
Begay RL, Tharp CA, Martin A, Graw SL, Sinagra G, Miani D, Sweet ME, Slavov DB, Stafford N, Zeller MJ, Alnefaie R, Rowland TJ, Brun F, Jones KL, Gowan K, Mestroni L, Garrity DM, Taylor MR
Citation:
JACC Basic Transl Sci. 2016 Aug;1(5):344-359. doi: 10.1016/j.jacbts.2016.05.004
Epub:
Not Epub
Abstract:
OBJECTIVE: To identify novel dilated cardiomyopathy (DCM) causing genes, and to elucidate the pathological mechanism leading to...
Link:
http://www.basictranslational.onlinejacc.org/content/early/2016/06/29/j.jacbts.2016.05.004
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Begay RL, Tharp CA, Martin A, Graw SL, Sinagra G, Miani D, Sweet ME, Slavov DB, Stafford N, Zeller MJ, Alnefaie R, Rowland TJ, Brun F, Jones KL, Gowan K, Mestroni L, Garrity DM, Taylor MR. FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy. JACC Basic Transl Sci. 2016 Aug;1(5):344-359. doi: 10.1016/j.jacbts.2016.05.004.

Neural Crest Migration and Survival Are Susceptible to Morpholino-Induced Artifacts

Authors:
Boer EF, Jette CA, Stewart RA
Citation:
PLoS One. 2016 Dec 22;11(12):e0167278. doi: 10.1371/journal.pone.0167278
Epub:
Not Epub
Abstract:
The neural crest (NC) is a stem cell-like embryonic population that is essential for generating and patterning the vertebrate...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167278
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boer EF, Jette CA, Stewart RA. Neural Crest Migration and Survival Are Susceptible to Morpholino-Induced Artifacts. PLoS One. 2016 Dec 22;11(12):e0167278. doi: 10.1371/journal.pone.0167278.

Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo

Authors:
Sully EK, Geller BL, Li L, Moody CM, Bailey SM, Moore AL, Wong M, Nordmann P, Daly SM, Sturge CR, Greenberg DE
Citation:
J Antimicrob Chemother. 2016 Dec 20. pii: dkw476. doi: 10.1093/jac/dkw476. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVES: The objective of this study was to test the efficacy of an inhibitor of the New Delhi metallo-β- lactamase (NDM-1...
Link:
http://jac.oxfordjournals.org/content/early/2016/12/02/jac.dkw476.abstract
Delivery Method:
peptide-linked
Organism or Cell Type:
Escherichia coli
Citation Extract:
Sully EK, Geller BL, Li L, Moody CM, Bailey SM, Moore AL, Wong M, Nordmann P, Daly SM, Sturge CR, Greenberg DE. Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo. J Antimicrob Chemother. 2016 Dec 20. pii: dkw476. doi: 10.1093/jac/dkw476. [Epub ahead of print].

CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes

Authors:
Zhang T, Zhou Y, Li L, Wang ZB, Shen W, Schatten H, Sun QY
Citation:
Development. 2016 Dec 19. pii: dev.141135. [Epub ahead of print]
Epub:
Yes
Abstract:
Meiotic resumption (G2/M transition) and progression through meiosis I (MI) are two critical stages for producing fertilization...
Link:
http://dev.biologists.org/content/early/2016/12/17/dev.141135.long
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Zhang T, Zhou Y, Li L, Wang ZB, Shen W, Schatten H, Sun QY. CenpH regulates meiotic G2/M transition by modulating the APC/CCdh1-cyclin B1 pathway in oocytes. Development. 2016 Dec 19. pii: dev.141135. [Epub ahead of print].

Sema3d controls collective endothelial cell migration by distinct mechanisms via Nrp1 and PlxnD1

Authors:
Hamm MJ, Kirchmaier BC, Herzog W
Citation:
J Cell Biol. 2016 Nov 7;215(3):415-430
Epub:
Not Epub
Abstract:
During cardiovascular development, tight spatiotemporal regulation of molecular cues is essential for controlling endothelial...
Link:
http://jcb.rupress.org/content/215/3/415.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hamm MJ, Kirchmaier BC, Herzog W. Sema3d controls collective endothelial cell migration by distinct mechanisms via Nrp1 and PlxnD1. J Cell Biol. 2016 Nov 7;215(3):415-430.

Regulator of G protein signaling 2 (Rgs2) regulates neural crest development through Pparδ-Sox10 cascade

Authors:
Lin SJ, Chiang MC, Shih HY, Hsu LS, Yeh TH, Huang YC, Lin CY, Cheng YC
Citation:
Biochim Biophys Acta. 2016 Dec 12. pii: S0167-4889(16)30338-X. doi: 10.1016/j.bbamcr.2016.12.013. [Epub ahead of print]
Epub:
Yes
Abstract:
Neural crest cells are multipotent progenitors that migrate extensively and differentiate into numerous derivatives. The...
Link:
http://www.sciencedirect.com/science/article/pii/S016748891630338X
Organism or Cell Type:
zebrafish
Citation Extract:
Lin SJ, Chiang MC, Shih HY, Hsu LS, Yeh TH, Huang YC, Lin CY, Cheng YC. Regulator of G protein signaling 2 (Rgs2) regulates neural crest development through Pparδ-Sox10 cascade. Biochim Biophys Acta. 2016 Dec 12. pii: S0167-4889(16)30338-X. doi: 10.1016/j.bbamcr.2016.12.013. [Epub ahead of print].

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