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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Proliferation-independent regulation of organ size by Fgf/Notch signaling

Authors:
Kozlovskaja-Gumbrienė A, Yi R, Alexander R, Aman A, Jiskra R, Nagelberg D, Knaut H, McClain M, Piotrowski T
Citation:
Elife. 2017 Jan 13;6. pii: e21049. doi: 10.7554/eLife.21049
Epub:
Not Epub
Abstract:
Organ morphogenesis depends on the precise orchestration of cell migration, cell shape changes and cell adhesion. We...
Link:
https://elifesciences.org/content/6/e21049
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kozlovskaja-Gumbrienė A, Yi R, Alexander R, Aman A, Jiskra R, Nagelberg D, Knaut H, McClain M, Piotrowski T. Proliferation-independent regulation of organ size by Fgf/Notch signaling. Elife. 2017 Jan 13;6. pii: e21049. doi: 10.7554/eLife.21049.

Spinal cord regeneration in Xenopus laevis

Authors:
Edwards-Faret G, Muñoz R, Méndez-Olivos EE, Lee-Liu D, Tapia VS, Larraín J
Citation:
Nat Protoc. 2017 Feb;12(2):372-389. doi: 10.1038/nprot.2016.177
Epub:
Not Epub
Abstract:
Here we present a protocol for the husbandry of Xenopus laevis tadpoles and froglets, and procedures to study spinal cord...
Link:
http://www.nature.com/nprot/journal/v12/n2/full/nprot.2016.177.html
Delivery Method:
electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Edwards-Faret G, Muñoz R, Méndez-Olivos EE, Lee-Liu D, Tapia VS, Larraín J. Spinal cord regeneration in Xenopus laevis. Nat Protoc. 2017 Feb;12(2):372-389. doi: 10.1038/nprot.2016.177.

Dual Functional Roles of Molecular Beacon: a MicroRNA Detector and Inhibitor

Authors:
Li WM, Chan CM, Miller AL, Lee CH
Citation:
J Biol Chem. 2017 Jan 18. pii: jbc.M116.765776. doi: 10.1074/jbc.M116.765776. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNAs are essential in many cellular processes. The ability to detect microRNAs is important for understanding its function...
Link:
http://www.jbc.org/content/early/2017/01/18/jbc.M116.765776.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li WM, Chan CM, Miller AL, Lee CH. Dual Functional Roles of Molecular Beacon: a MicroRNA Detector and Inhibitor. J Biol Chem. 2017 Jan 18. pii: jbc.M116.765776. doi: 10.1074/jbc.M116.765776. [Epub ahead of print].

Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing

Authors:
Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çağlayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG
Citation:
Nat Genet. 2017 Jan 16. doi: 10.1038/ng.3762. [Epub ahead of print]
Epub:
Yes
Abstract:
Deadenylases are best known for degrading the poly(A) tail during mRNA decay. The deadenylase family has expanded throughout...
Link:
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3762.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çağlayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG. Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet. 2017 Jan 16. doi: 10.1038/ng.3762. [Epub ahead of print].

A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors

Authors:
Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM Jr, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL
Citation:
Cell Rep. 2017 Jan 17;18(3):762-776. doi: 10.1016/j.celrep.2016.12.063
Epub:
Not Epub
Abstract:
Mammals have extremely limited regenerative capabilities; however, axolotls are profoundly regenerative and can replace entire...
Link:
http://www.cell.com/cell-reports/abstract/S2211-1247(16)31770-3
Delivery Method:
electroporation
Organism or Cell Type:
Ambystoma mexicanum (Axolotl)
Citation Extract:
Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM Jr, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL. A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors. Cell Rep. 2017 Jan 17;18(3):762-776. doi: 10.1016/j.celrep.2016.12.063.

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Authors:
Ohki Y, Wenninger-Weinzierl A, Hruscha A, Asakawa K, Kawakami K, Haass C, Edbauer D, Schmid B
Citation:
Mol Neurodegener. 2017 Jan 14;12(1):6. doi:10.1186/s13024-016-0146-8
Epub:
Not Epub
Abstract:
BACKGROUND: The most frequent genetic cause of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS...
Link:
https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-016-0146-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ohki Y, Wenninger-Weinzierl A, Hruscha A, Asakawa K, Kawakami K, Haass C, Edbauer D, Schmid B. Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration. Mol Neurodegener. 2017 Jan 14;12(1):6. doi:10.1186/s13024-016-0146-8.

The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation

Authors:
Esser JS, Charlet A, Schmidt M, Heck S, Allen A, Lother A, Epting D, Patterson C, Bode C, Moser M
Citation:
Cardiovasc Res. 2017 Jan 12. pii: cvw248. doi: 10.1093/cvr/cvw248. [Epub ahead of print]
Epub:
Yes
Abstract:
RATIONALE: Regarding branching morphogenesis, neurogenesis and angiogenesis share common principle mechanisms and make use of...
Link:
http://cardiovascres.oxfordjournals.org/content/early/2017/01/12/cvr.cvw248.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Esser JS, Charlet A, Schmidt M, Heck S, Allen A, Lother A, Epting D, Patterson C, Bode C, Moser M. The neuronal transcription factor NPAS4 is a strong inducer of sprouting angiogenesis and tip cell formation. Cardiovasc Res. 2017 Jan 12. pii: cvw248. doi: 10.1093/cvr/cvw248. [Epub ahead of print].

Ftr82 Is Critical for Vascular Patterning during Zebrafish Development

Authors:
Chang H-W, Wang W-D, Chiu C-C, Chen C-H, Wang Y-S, Chen Z-Y, Liu W, Tai M-H, Wen Z-H, Wu C-Y
Citation:
Int J Mol Sci. 2017;18(1):156. doi:10.3390/ijms18010156
Epub:
Not Epub
Abstract:
Cellular components and signaling pathways are required for the proper growth of blood vessels. Here, we report for the first...
Link:
http://www.mdpi.com/1422-0067/18/1/156
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chang H-W, Wang W-D, Chiu C-C, Chen C-H, Wang Y-S, Chen Z-Y, Liu W, Tai M-H, Wen Z-H, Wu C-Y. Ftr82 Is Critical for Vascular Patterning during Zebrafish Development. Int J Mol Sci. 2017;18(1):156. doi:10.3390/ijms18010156.

Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis

Authors:
Macia MS, Halbritter J, Delous M, Bredrup C, Gutter A, Filhol E, Mellgren AEC, Leh S, Bizet A, Braun DA, Gee HY, Silbermann F, Henry C, Krug P, Bole-Feysot C, Nitschké P, Joly D, Nicoud P, Paget A, Haugland H, Brackmann D, Ahmet N, Sandford R, Cengiz N, Knappskog PM, Boman H, Linghu B, Yang F, Oakeley EJ, Mézard SP, Sailer AW, Johansson S, Rødah E, Saunier S, Hildebrandt F, Benmerah A
Citation:
Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2016.12.011
Epub:
Yes
Abstract:
Nephronophthisis (NPH), an autosomal-recessive tubulointerstitial nephritis, is the most common cause of hereditary end-stage...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297(16)30535-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Macia MS, Halbritter J, Delous M, Bredrup C, Gutter A, Filhol E, Mellgren AEC, Leh S, Bizet A, Braun DA, Gee HY, Silbermann F, Henry C, Krug P, Bole-Feysot C, Nitschké P, Joly D, Nicoud P, Paget A, Haugland H, Brackmann D, Ahmet N, Sandford R, Cengiz N, Knappskog PM, Boman H, Linghu B, Yang F, Oakeley EJ, Mézard SP, Sailer AW, Johansson S, Rødah E, Saunier S, Hildebrandt F, Benmerah A. Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis. Am J Hum Genet. 2017;[Epub ahead of print] doi:10.1016/j.ajhg.2016.12.011.

Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes

Authors:
Sun TY, Wang HY, Kwon JW, Yuan B, Lee IW, Cui XS, Kim NH
Citation:
Cell Cycle. 2017 Jan 11:0. doi: 10.1080/15384101.2016.1264544. [Epub ahead of print]
Epub:
Yes
Abstract:
Unlike somatic cells mitosis, germ cell meiosis consists of two consecutive rounds of division that segregate homologous...
Link:
http://tandfonline.com/doi/full/10.1080/15384101.2016.1264544
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Sun TY, Wang HY, Kwon JW, Yuan B, Lee IW, Cui XS, Kim NH. Centriolin, a centriole-appendage protein, regulates peripheral spindle migration and asymmetric division in mouse meiotic oocytes. Cell Cycle. 2017 Jan 11:0. doi: 10.1080/15384101.2016.1264544. [Epub ahead of print].

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