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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

R-spondin 1 is required for specification of hematopoietic stem cells through Wnt16 and Vegfa signaling pathways

Authors:
Genthe JR, Clements WK
Citation:
Development. 2017 Feb 15;144(4):590-600. doi: 10.1242/dev.139956
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) are the therapeutic component of bone marrow transplants, but finding immune-compatible donors...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Genthe JR, Clements WK. R-spondin 1 is required for specification of hematopoietic stem cells through Wnt16 and Vegfa signaling pathways. Development. 2017 Feb 15;144(4):590-600. doi: 10.1242/dev.139956.

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse

Authors:
Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ
Citation:
Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155
Epub:
Not Epub
Abstract:
Splice modulation therapy has shown great clinical promise in Duchenne muscular dystrophy, resulting in the production of...
Delivery Method:
peptide-linked
Organism or Cell Type:
mouse mdx
Citation Extract:
Godfrey C, Muses S, McClorey G, Wells KE, Coursindel T, Terry RL, Betts C, Hammond S, O'Donovan L, Hildyard J, El Andaloussi S, Gait MJ, Wood MJ, Wells DJ. How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse. Hum Mol Genet. 2015 Aug 1;24(15):4225-37. doi: 10.1093/hmg/ddv155.

Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation

Authors:
Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, Galvez F, Huffmaster NJ, Tripathi S, Balasubramaniam VRMT, Inoue A, de Castro E, Moulton H, Stein DA, Sánchez-Aparicio MT, De Jesus PD, Nguyen Q, König R, Krogan NJ, García-Sastre A, Yoh SM, Chanda SK
Citation:
Nat Microbio. 2017;2:17022. doi:10.1038/nmicrobiol.2017.22
Epub:
Not Epub
Abstract:
Retinoic acid-inducible gene I (RIG-I) receptor recognizes 5′-triphosphorylated RNA and triggers a signalling cascade that...
Delivery Method:
peptide-linked
Organism or Cell Type:
mice C57BL/6
Citation Extract:
Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, Galvez F, Huffmaster NJ, Tripathi S, Balasubramaniam VRMT, Inoue A, de Castro E, Moulton H, Stein DA, Sánchez-Aparicio MT, De Jesus PD, Nguyen Q, König R, Krogan NJ, García-Sastre A, Yoh SM, Chanda SK. Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation. Nat Microbio. 2017;2:17022. doi:10.1038/nmicrobiol.2017.22.

Dynamics of ASC speck formation during skin inflammatory responses in vivo

Authors:
Rodriguez PSK, Schieber N, Thumberger T, Wittbrodt J, Schwab Y, Leptin M
Citation:
bioRxiv. 2017. doi:10.1101/111542
Epub:
Yes
Abstract:
Activated danger or pathogen sensors trigger assembly of the inflammasome adaptor ASC into specks, large signalling platforms...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rodriguez PSK, Schieber N, Thumberger T, Wittbrodt J, Schwab Y, Leptin M. Dynamics of ASC speck formation during skin inflammatory responses in vivo. bioRxiv. 2017. doi:10.1101/111542.

Stomach curvature is generated by left-right asymmetric gut morphogenesis

Authors:
Davis A, Amin NM, Johnson C, Bagley K, Ghashghaei HT, Nascone-Yoder N
Citation:
Development, 2017;[Epub ahead of print] doi: 10.1242/dev.143701
Epub:
Yes
Abstract:
Left-right (LR) asymmetry is a fundamental feature of internal anatomy, yet the emergence of morphological asymmetry remains...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Davis A, Amin NM, Johnson C, Bagley K, Ghashghaei HT, Nascone-Yoder N. Stomach curvature is generated by left-right asymmetric gut morphogenesis. Development, 2017;[Epub ahead of print] doi: 10.1242/dev.143701.

Characterization of membrane progestin receptor α (mPRα) of the medaka and role in the induction of oocyte maturation

Authors:
Roy SR, Wang J, Rana MR, Nakashima M, Tokumoto T
Citation:
Biomed Res. 2017;38(1):79-87. doi: 10.2220/biomedres.38.79
Epub:
Not Epub
Abstract:
Oocyte maturation in medaka is induced by the maturation-inducing hormone (MIH) via its membrane receptor. The most likely...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Roy SR, Wang J, Rana MR, Nakashima M, Tokumoto T. Characterization of membrane progestin receptor α (mPRα) of the medaka and role in the induction of oocyte maturation. Biomed Res. 2017;38(1):79-87. doi: 10.2220/biomedres.38.79.

Tissue specific regulation of the chick Sox10E1 enhancer by different Sox family members

Authors:
Murko C, Bronner ME
Citation:
Dev Biol. 2017 Feb 1;422(1):47-57. doi: 10.1016/j.ydbio.2016.12.004
Epub:
Not Epub
Abstract:
The transcription factor Sox10 is a key regulator of vertebrate neural crest development and serves crucial functions in the...
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Murko C, Bronner ME. Tissue specific regulation of the chick Sox10E1 enhancer by different Sox family members. Dev Biol. 2017 Feb 1;422(1):47-57. doi: 10.1016/j.ydbio.2016.12.004.

The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis

Authors:
Hempel A, Kühl SJ, Rothe M, Rao Tata P, Ovidiu Sirbu I, Vainio S, Kühl M
Citation:
Dev Biol. 2017 Feb 22. pii: S0012-1606(16)30865-X. doi: 10.1016/j.ydbio.2017.02.014. [Epub ahead of print]
Epub:
Yes
Abstract:
Wnt proteins are critical for embryonic cardiogenesis and cardiomyogenesis by regulating different intracellular signalling...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Hempel A, Kühl SJ, Rothe M, Rao Tata P, Ovidiu Sirbu I, Vainio S, Kühl M. The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis. Dev Biol. 2017 Feb 22. pii: S0012-1606(16)30865-X. doi: 10.1016/j.ydbio.2017.02.014. [Epub ahead of print].

Cell division and cadherin-mediated adhesion regulate lens epithelial cell movement in zebrafish

Authors:
Mochizuki T, Luo YJ, Tsai HF, Hagiwara A, Masai I
Citation:
Development. 2017 Feb 15;144(4):708-719. doi: 10.1242/dev.138909
Epub:
Not Epub
Abstract:
In vertebrates, lens epithelial cells cover the anterior half of the lens fiber core. During development, lens epithelial cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mochizuki T, Luo YJ, Tsai HF, Hagiwara A, Masai I. Cell division and cadherin-mediated adhesion regulate lens epithelial cell movement in zebrafish. Development. 2017 Feb 15;144(4):708-719. doi: 10.1242/dev.138909.

Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer

Authors:
Cook KL, Soto-Pantoja DR, Clarke PA, Cruz MI, Zwart A, Wärri A, Hilakivi-Clarke L, Roberts DD, Clarke R
Citation:
Cancer Res. 2016 Oct 1;76(19):5657-5670
Epub:
Not Epub
Abstract:
The unfolded protein response is an endoplasmic reticulum stress pathway mediated by the protein chaperone glucose regulated-...
Citation Extract:
Cook KL, Soto-Pantoja DR, Clarke PA, Cruz MI, Zwart A, Wärri A, Hilakivi-Clarke L, Roberts DD, Clarke R. Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer. Cancer Res. 2016 Oct 1;76(19):5657-5670.

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