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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation
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Citation:
EMBO Mol Med. 2017 Jul 3. pii: e201607315. doi: 10.15252/emmm.201607315. [Epub ahead of print] Epub:
Yes Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is a lethal premature and accelerated aging disease caused by a de novo point... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary dermal fibroblasts Citation Extract: Harhouri K, Navarro C, Depetris D, Mattei MG, Nissan X, Cau P, De Sandre-Giovannoli A, Lévy N. MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation. EMBO Mol Med. 2017 Jul 3. pii: e201607315. doi: 10.15252/emmm.201607315. [Epub ahead of print]. |
A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome
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Citation:
Nat Comm. 2017;8:16077. doi:10.1038/ncomms16077 Epub:
Not Epub Abstract:
Multinucleate cellular syncytial formation is a hallmark of skeletal muscle differentiation. Myomaker, encoded by Mymk (Tmem8c... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Di Gioia SA, Connors S, Matsunami N, Cannavino J, Rose MF, Gilette NM, Artoni P, de Macena Sobreira NL, Chan W-M, Webb BD, Robson CD, Cheng L, Van Ryzin C, Ramirez-Martinez A, Payam Mohassel, Leppert M, Scholand MB, Grunseich C, Ferreira CR, Hartman T, Hayes IM, Morgan T, Markie DM, Fagiolini M, Swift A, Chines PS, Speck-Martins CE, Collins FS, Jabs EW, Bönnemann CG, Olson EN, Moebius Syndrome Research Consortium, Carey JC, Robertson SP, Manoli I, Engle EC. A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome. Nat Comm. 2017;8:16077. doi:10.1038/ncomms16077. |
Myosin-independent cytokinesis in Giardia utilizes flagella to coordinate force generation and direct membrane trafficking
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Citation:
Proc Natl Acad Sci USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1705096114 Epub:
Yes Abstract:
Devoid of all known canonical actin-binding proteins, the prevalent parasite Giardia lamblia uses an alternative mechanism for... Organism or Cell Type:
Giardia lamblia Citation Extract: Hardin WR, Li R, Xu J, Shelton AM, Alas GCM, Minin VN, Paredez AR. Myosin-independent cytokinesis in Giardia utilizes flagella to coordinate force generation and direct membrane trafficking. Proc Natl Acad Sci USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1705096114. |
New role of LRP5, associated with non-syndromic autosomal recessive hereditary hearing loss
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Citation:
Hum Mutat. 2017 Jul 4. doi: 10.1002/humu.23285. [Epub ahead of print] Epub:
Yes Abstract:
Human hearing loss is a common neurosensory disorder about which many basic research and clinically relevant questions are... Organism or Cell Type:
zebrafish Citation Extract: Xia W, Hu J, Liu F, Ma J, Sun S, Zhang J, Jin K, Huang J, Jiang N, Wang X, Li W, Ma Z, Ma D. New role of LRP5, associated with non-syndromic autosomal recessive hereditary hearing loss. Hum Mutat. 2017 Jul 4. doi: 10.1002/humu.23285. [Epub ahead of print]. |
In Vivo Regulation of the Zebrafish Endoderm Progenitor Niche by T-Box Transcription Factors
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Citation:
Cell Rep. 2017 Jun 27;19(13):2782-2795. doi: 10.1016/j.celrep.2017.06.011 Epub:
Not Epub Abstract:
T-box transcription factors T/Brachyury homolog A (Ta) and Tbx16 are essential for correct mesoderm development in zebrafish.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nelson AC, Cutty SJ, Gasiunas SN, Deplae I, Stemple DL, Wardle FC. In Vivo Regulation of the Zebrafish Endoderm Progenitor Niche by T-Box Transcription Factors. Cell Rep. 2017 Jun 27;19(13):2782-2795. doi: 10.1016/j.celrep.2017.06.011. |
Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2
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Citation:
Elife. 2017 Jun 27;6. pii: e21526. doi: 10.7554/eLife.21526 Epub:
Not Epub Abstract:
During early embryogenesis, cells must exit pluripotency and commit to multiple lineages in all germ-layers. How this... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Scerbo P, Marchal L, Kodjabachian L. Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2. Elife. 2017 Jun 27;6. pii: e21526. doi: 10.7554/eLife.21526. |
E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP
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Citation:
Nat Commun. 2017 Jun 28;8:15865. doi: 10.1038/ncomms15865 Epub:
Not Epub Abstract:
Optimal regulation of the innate immune receptor nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice C57BL/6J Citation Extract: Bist P, Cheong WS, Ng A, Dikshit N, Kim BH, Pulloor NK, Khameneh HJ, Hedl M, Shenoy AR, Balamuralidhar V, Malik NBA, Hong M, Neutzner A, Chin KC, Kobayashi KS, Bertoletti A, Mortellaro A, Abraham C, MacMicking JD, Xavier RJ, Sukumaran B. E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP. Nat Commun. 2017 Jun 28;8:15865. doi: 10.1038/ncomms15865. |
Neutrophil derived LTB4 induces macrophage aggregation in response to encapsulated Streptococcus iniae infection
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Citation:
PLoS ONE. 2017:12(6):e0179574. doi:10.1371/journal.pone.0179574 Epub:
Not Epub Abstract:
Immune cells sense and react to a multitude of factors including both host and microbe-derived signals. Understanding how cells... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vincent WJB, Harvie EA, Sauer J-D, Huttenlocher A. Neutrophil derived LTB4 induces macrophage aggregation in response to encapsulated Streptococcus iniae infection. PLoS ONE. 2017:12(6):e0179574. doi:10.1371/journal.pone.0179574. |
Septins restrict inflammation and protect zebrafish larvae from Shigella infection
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Citation:
PLoS Pathog. 2017;13(6):e1006467. https://doi.org/10.1371/journal.ppat.1006467 Epub:
Not Epub Abstract:
Shigella flexneri, a Gram-negative enteroinvasive pathogen, causes inflammatory destruction of the human colonic epithelium.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mazon-Moya MJ, Willis AR, Torraca V, Boucontet L, Shenoy AR, Colucci-Guyon E, Mostowy S. Septins restrict inflammation and protect zebrafish larvae from Shigella infection. PLoS Pathog. 2017;13(6):e1006467. https://doi.org/10.1371/journal.ppat.1006467. |
Antagonistic BMP-cWNT signaling in the cnidarian Nematostella vectensis reveals insight into the evolution of mesoderm
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Citation:
Proc Natl Acad Sci U S A. 2017 Jun 26. pii: 201701607. doi: 10.1073/pnas.1701607114. [Epub ahead of print] Epub:
Yes Abstract:
Gastrulation was arguably the key evolutionary innovation that enabled metazoan diversification, leading to the formation of... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Wijesena N, Simmons DK, Martindale MQ. Antagonistic BMP-cWNT signaling in the cnidarian Nematostella vectensis reveals insight into the evolution of mesoderm. Proc Natl Acad Sci U S A. 2017 Jun 26. pii: 201701607. doi: 10.1073/pnas.1701607114. [Epub ahead of print]. |