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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
In Vitro Modulation of Endogenous Alternative Splicing Using Splice-Switching Antisense Oligonucleotides
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Citation:
Methods Mol Biol. 2017;1648:39-52. doi: 10.1007/978-1-4939-7204-3_4 Epub:
Not Epub Abstract:
Regulation of alternative splicing can be harnessed by antisense-based compounds to control gene expression. Antisense-mediated... Organism or Cell Type:
cell culture Citation Extract: Park JE, Cartegni L. In Vitro Modulation of Endogenous Alternative Splicing Using Splice-Switching Antisense Oligonucleotides. Methods Mol Biol. 2017;1648:39-52. doi: 10.1007/978-1-4939-7204-3_4. |
N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis
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Citation:
J Neurosci. 2017;[Published online] doi:10.1523/JNEUROSCI.3881-16.2017 Epub:
Not Epub Abstract:
The presence of the neuronal-specific N1-Src splice variant of the C-Src tyrosine kinase is conserved through vertebrate... Organism or Cell Type:
Xenopus tropicalis Citation Extract: Lewis PA, Bradley IC, Pizzey AR, Isaacs HV, Evans GJO. N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis. J Neurosci. 2017;[Published online] doi:10.1523/JNEUROSCI.3881-16.2017. |
Metformin Inhibits Cyst Formation in a Zebrafish Model of Polycystin-2 Deficiency
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Citation:
Sci Rep. 2017;7:7161. doi:10.1038/s41598-017-07300-x Epub:
Not Epub Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is a common kidney disease caused by mutations in PKD1 or PKD2. Metformin... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chang M-Y, Ma T-L, Hung C-C, Tian Y-C, Chen Y-C, Yang C-W, Cheng Y-C. Metformin Inhibits Cyst Formation in a Zebrafish Model of Polycystin-2 Deficiency. Sci Rep. 2017;7:7161. doi:10.1038/s41598-017-07300-x. |
Flow-Responsive VEGFR-PKCɛ Signaling Mediates Glycolytic Metabolites for Vascular Repair
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Citation:
Antioxid Redox Signal. 2017 Aug 1. doi: 10.1089/ars.2017.7044. [Epub ahead of print] Epub:
Yes Abstract:
Aims - Hemodynamic shear stress participates in maintaining vascular redox status. Elucidating flow-mediated endothelial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Baek KI, Li R, Jen N, Choi H, Kaboodrangi A, Ping P, Liem D, Beebe T, Hsiai TK. Flow-Responsive VEGFR-PKCɛ Signaling Mediates Glycolytic Metabolites for Vascular Repair. Antioxid Redox Signal. 2017 Aug 1. doi: 10.1089/ars.2017.7044. [Epub ahead of print]. |
Nanog suppresses the expression of vasa by directly regulating nlk1 in the early zebrafish embryo
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Citation:
Biochimie. 2017 Jul 28. pii: S0300-9084(17)30185-2. doi: 10.1016/j.biochi.2017.07.014. [Epub ahead of print] Epub:
Yes Abstract:
Nanog is a homeodomain transcription factor that is essential for maintenance of pluripotency and self-renewal of embryonic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Liu Y, Xue W, Zhu L, Ye D, Zhu X, Wang H, Sun Y, Deng F. Nanog suppresses the expression of vasa by directly regulating nlk1 in the early zebrafish embryo. Biochimie. 2017 Jul 28. pii: S0300-9084(17)30185-2. doi: 10.1016/j.biochi.2017.07.014. [Epub ahead of print]. |
Tensile forces govern germ-layer organization in zebrafish
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Citation:
Nat Cell Biol. 2008 Apr;10(4):429-36. doi: 10.1038/ncb1705. Epub 2008 Mar 23 Epub:
Not Epub Abstract:
Understanding the factors that direct tissue organization during development is one of the most fundamental goals in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Krieg M, Arboleda-Estudillo Y, Puech PH, Käfer J, Graner F, Müller DJ, Heisenberg CP. Tensile forces govern germ-layer organization in zebrafish. Nat Cell Biol. 2008 Apr;10(4):429-36. doi: 10.1038/ncb1705. Epub 2008 Mar 23. |
Sorting at embryonic boundaries requires high heterotypic interfacial tension
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Citation:
Nat Comm. 2017;8:157 doi:10.1038/s41467-017-00146-x Epub:
Not Epub Abstract:
The establishment of sharp boundaries is essential for segregation of embryonic tissues during development, but the underlying... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Canty L, Zarour E, Kashkooli L, François P, Fagotto F. Sorting at embryonic boundaries requires high heterotypic interfacial tension. Nat Comm. 2017;8:157 doi:10.1038/s41467-017-00146-x. |
Pituitary adenylate cyclase-activating polypeptide (PACAP) in zebrafish models of nephrotic syndrome
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Citation:
PLoS ONE. 2017;12(7):e0182100. doi:journal.pone.0182100 Epub:
Not Epub Abstract:
Pituitary adenylate cyclase-activating polypeptide (PACAP) is an inhibitor of megakaryopoiesis and platelet function. Recently... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Eneman B, Elmonem MA, van den Heuvel LP, Khodaparast L, Khodaparast L, van Geet C, Freson K, Levtchenko E. Pituitary adenylate cyclase-activating polypeptide (PACAP) in zebrafish models of nephrotic syndrome. PLoS ONE. 2017;12(7):e0182100. doi:journal.pone.0182100. |
Quantitative antisense screening and optimization for exon 51 skipping in Duchenne muscular dystrophy
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Citation:
Molec Ther. 2017:[Accepted manucsript] doi:10.1016/j.ymthe.2017.07.014 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD), the most common lethal genetic disorder, is caused by mutations in the dystrophin (DMD) gene... Organism or Cell Type:
cell culture: immortalized DMD muscle cells, humanized DMD mice Citation Extract: Echigoya Y, Rowel Q. Lim KRQ, Trieu N, Bao B, Miskew B, Vila MC, Novak JS, Hara Y, Lee J, Touznik A, Mamchaoui K, Aoki Y, Takeda S, Nagaraju K, Mouly V, Maruyama R, Duddy W, Yokota T. Quantitative antisense screening and optimization for exon 51 skipping in Duchenne muscular dystrophy. Molec Ther. 2017:[Accepted manucsript] doi:10.1016/j.ymthe.2017.07.014. |
Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors
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Citation:
Cancer Gene Ther. 2017:[Advance publication] doi:10.1038/cgt.2017.27 Epub:
Not Epub Abstract:
The DNA repair enzyme O6-methylguanine DNA methyltransferase (MGMT) is epigenetically silenced in some tumors by MGMT gene... Delivery Method:
scrape, DharmaFECT, ionizing radiation Organism or Cell Type:
cell culture: T98G glioma, H460 and A549 non-small cell lung carcinoma, xenograft mice Citation Extract: Ambady P, Wu YJ, Walker JM, Kersch C, Pagel MA, Woltjer RL, Fu R, Muldoon LL, Neuwelt EA. Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors. Cancer Gene Ther. 2017:[Advance publication] doi:10.1038/cgt.2017.27. |