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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

The 16p11.2 homologs fam57ba and doc2a generate certain brain and body phenotypes

Authors:
McCammon JM, Blaker-Lee A, Chen X, Sive H
Citation:
Hum Mol Genet. 2017;[Epub ahead of print] doi:10.1093/hmg/ddx255
Epub:
Yes
Abstract:
Deletion of the 16p11.2 CNV affects 25 core genes and is associated with multiple symptoms affecting brain and body, including...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McCammon JM, Blaker-Lee A, Chen X, Sive H. The 16p11.2 homologs fam57ba and doc2a generate certain brain and body phenotypes. Hum Mol Genet. 2017;[Epub ahead of print] doi:10.1093/hmg/ddx255.

Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signalings in the zebrafish embryo

Authors:
Bian SS, Zheng XL, Sun HQ, Chen JH, Lu YL, Liu YQ, Tao DC, Ma YX
Citation:
J Biol Chem. 2017 Jul 7. pii: jbc.M117.794289. doi: 10.1074/jbc.M117.794289. [Epub ahead of print]
Epub:
Yes
Abstract:
Circadian clock and Smad2/3/4-mediated Nodal signaling regulate multiple physiological and pathological processes. However, it...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bian SS, Zheng XL, Sun HQ, Chen JH, Lu YL, Liu YQ, Tao DC, Ma YX. Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signalings in the zebrafish embryo. J Biol Chem. 2017 Jul 7. pii: jbc.M117.794289. doi: 10.1074/jbc.M117.794289. [Epub ahead of print].

DYRK2 displays muscle fiber type specific function during zebrafish early somitogenesis

Authors:
Sun W, Jiao S, Tan X, Zhang P, You F
Citation:
Int J Dev Biol. 2017;61(6-7):459-463. doi: 10.1387/ijdb.160175sj
Epub:
Not Epub
Abstract:
Dual specificity tyrosine-phosphorylation regulated kinase 2 (DYRK2) is a serine/threonine kinase. In zebrafish, DYRK2 is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun W, Jiao S, Tan X, Zhang P, You F. DYRK2 displays muscle fiber type specific function during zebrafish early somitogenesis. Int J Dev Biol. 2017;61(6-7):459-463. doi: 10.1387/ijdb.160175sj.

Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy

Authors:
Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B
Citation:
J Am Soc Nephrol. 2017 Jul 10. pii: ASN.2016101123. doi: 10.1681/ASN.2016101123. [Epub ahead of print]
Epub:
Yes
Abstract:
Established therapies for diabetic nephropathy (dNP) delay but do not prevent its progression. The shortage of established...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B. Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy. J Am Soc Nephrol. 2017 Jul 10. pii: ASN.2016101123. doi: 10.1681/ASN.2016101123. [Epub ahead of print].

Role of Mad2 expression during the early development of the sea urchin

Authors:
Bronchain O, Jdey W, Caraty L, Ciapa
Citation:
Int J Dev Biol. B2017;61(6-7):451-457. doi: 10.1387/ijdb.170053bc
Epub:
Not Epub
Abstract:
Mitotic arrest deficient 2 (Mad2) belongs to the spindle assembly checkpoint (SAC), a mechanism that blocks progression of the...
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Bronchain O, Jdey W, Caraty L, Ciapa. Role of Mad2 expression during the early development of the sea urchin. Int J Dev Biol. B2017;61(6-7):451-457. doi: 10.1387/ijdb.170053bc.

A functional approach to understanding the role of NCKX5 in Xenopus pigmentation

Authors:
Williams RM, Winkfein RJ, Ginger RS, Green MR, Schnetkamp PP, Wheeler GN
Citation:
PLoS One. 2017 Jul 10;12(7):e0180465. doi: 10.1371/journal.pone.0180465. eCollection 2017
Epub:
Not Epub
Abstract:
NCKX5 is an ion exchanger expressed mostly in pigment cells; however, the functional role for this protein in melanogenesis is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Williams RM, Winkfein RJ, Ginger RS, Green MR, Schnetkamp PP, Wheeler GN. A functional approach to understanding the role of NCKX5 in Xenopus pigmentation. PLoS One. 2017 Jul 10;12(7):e0180465. doi: 10.1371/journal.pone.0180465. eCollection 2017.

Acetylcholinesterase plays a non-neuronal, non-esterase role in organogenesis

Authors:
Pickett MA, Dush MK, Nascone-Yoder NM
Citation:
Development. 2017 Jul 6. pii: dev.149831. doi: 10.1242/dev.149831. [Epub ahead of print]
Epub:
Yes
Abstract:
Acetylcholinesterase (AChE) is crucial for degrading acetylcholine at cholinergic synapses. In vitro studies suggest that, in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pickett MA, Dush MK, Nascone-Yoder NM. Acetylcholinesterase plays a non-neuronal, non-esterase role in organogenesis. Development. 2017 Jul 6. pii: dev.149831. doi: 10.1242/dev.149831. [Epub ahead of print].

Frizzled 3 acts upstream of Alcam during embryonic eye development

Authors:
Seigfried FA, Cizelsky W, Pfister AS, Dietmann P, Walther P, Kühl M, Kühl SJ
Citation:
Dev Biol. 2017 Jun 1;426(1):69-83. doi: 10.1016/j.ydbio.2017.04.004. Epub 2017 Apr 17
Epub:
Not Epub
Abstract:
Formation of a functional eye during vertebrate embryogenesis requires different processes such as cell differentiation, cell...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Seigfried FA, Cizelsky W, Pfister AS, Dietmann P, Walther P, Kühl M, Kühl SJ. Frizzled 3 acts upstream of Alcam during embryonic eye development. Dev Biol. 2017 Jun 1;426(1):69-83. doi: 10.1016/j.ydbio.2017.04.004. Epub 2017 Apr 17.

PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration

Authors:
Bahm I, Barriga EH, Frolov A, Theveneau E, Frankel P, Mayor R.
Citation:
Development. 2017 Jul 1;144(13):2456-2468. doi: 10.1242/dev.147926. Epub 2017 May 19
Epub:
Not Epub
Abstract:
A fundamental property of neural crest (NC) migration is contact inhibition of locomotion (CIL), a process by which cells...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bahm I, Barriga EH, Frolov A, Theveneau E, Frankel P, Mayor R.. PDGF controls contact inhibition of locomotion by regulating N-cadherin during neural crest migration. Development. 2017 Jul 1;144(13):2456-2468. doi: 10.1242/dev.147926. Epub 2017 May 19.

Daam1 regulates fascin for actin assembly in mouse oocyte meiosis

Authors:
Lu Y, Zhang Y, Pan MH, Kim NH, Sun SC, Cui XS
Citation:
Cell Cycle. 2017 Jul 6:0. doi: 10.1080/15384101.2017.1325045. [Epub ahead of print]
Epub:
Yes
Abstract:
As a formin protein, Daam1 (Dishevelled-associated activator of morphogenesis 1) is reported to regulate series of cell...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Lu Y, Zhang Y, Pan MH, Kim NH, Sun SC, Cui XS. Daam1 regulates fascin for actin assembly in mouse oocyte meiosis. Cell Cycle. 2017 Jul 6:0. doi: 10.1080/15384101.2017.1325045. [Epub ahead of print].

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