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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication
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Citation:
PLoS Pathog. 2017;13(10):e1006700. doi:10.1371/journal.ppat.1006700 Epub:
Not Epub Abstract:
Salmonella enterica serovar typhimurium extensively remodels the host late endocytic compartments to establish its vacuolar... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Sindhwani A, Arya SB, Kaur H, Jagga D, Tuli A, Sharma M. Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication. PLoS Pathog. 2017;13(10):e1006700. doi:10.1371/journal.ppat.1006700. |
Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
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Citation:
Nat Comm. 2017;8:1185. doi:10.1038/s41467-017-01107-0 Epub:
Not Epub Abstract:
Following epithelial-mesenchymal transition, acquisition of avian trunk neural crest cell (NCC) polarity is prerequisite for... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Liu JA, Rao Y, Cheung MPL, Hui M-N, Wu M-H, Chan L-K, Ng IO-L, Niu B, Cheah KSE, Sharma R, Hodgson L, Cheung M. Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration. Nat Comm. 2017;8:1185. doi:10.1038/s41467-017-01107-0. |
A method to quantify mechanobiologic forces during zebrafish cardiac development using 4-D light sheet imaging and computational modeling
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Citation:
PLoS Comput Biol. 2017;13(10):e1005828. doi:journal.pcbi.1005828 Epub:
Not Epub Abstract:
Blood flow and mechanical forces in the ventricle are implicated in cardiac development and trabeculation. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vedula V, Lee J, Xu H, Kuo C-CJ, Hsiai TK, Marsden AL. A method to quantify mechanobiologic forces during zebrafish cardiac development using 4-D light sheet imaging and computational modeling. PLoS Comput Biol. 2017;13(10):e1005828. doi:journal.pcbi.1005828. |
Sirt2-BubR1 acetylation pathway mediates the effects of advanced maternal age on oocyte quality
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Citation:
Aging Cell. 2017 Oct 25. doi: 10.1111/acel.12698. [Epub ahead of print] Epub:
Yes Abstract:
The level of Sirt2 protein is reduced in oocytes from aged mice, while exogenous expression of Sirt2 could ameliorate the... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Qiu D, Hou X, Han L, Li X, Ge J, Wang Q. Sirt2-BubR1 acetylation pathway mediates the effects of advanced maternal age on oocyte quality. Aging Cell. 2017 Oct 25. doi: 10.1111/acel.12698. [Epub ahead of print]. |
PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment
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Citation:
Methods Mol Biol. 2018;1687:185-192. doi: 10.1007/978-1-4939-7374-3_13 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration, caused by nonsense or... Delivery Method:
bubble liposome & ultrasound Organism or Cell Type:
mice Citation Extract: Negishi Y, Ishii Y, Nirasawa K, Sasaki E, Endo-Takahashi Y, Suzuki R, Maruyama K. PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment. Methods Mol Biol. 2018;1687:185-192. doi: 10.1007/978-1-4939-7374-3_13. |
Designing Effective Antisense Oligonucleotides for Exon Skipping
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Citation:
Methods Mol Biol. 2018;1687:143-155. doi: 10.1007/978-1-4939-7374-3_10 Epub:
Not Epub Abstract:
During the past 10 years, antisense oligonucleotide-mediated exon skipping and splice modulation have proven to be powerful... Citation Extract: Shimo T, Maruyama R, Yokota T.. Designing Effective Antisense Oligonucleotides for Exon Skipping. Methods Mol Biol. 2018;1687:143-155. doi: 10.1007/978-1-4939-7374-3_10. |
Exon Skipping Therapy Using Phosphorodiamidate Morpholino Oligomers in the mdx52 Mouse Model of Duchenne Muscular Dystrophy
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Citation:
Methods Mol Biol. 2018;1687:123-141. doi: 10.1007/978-1-4939-7374-3_9 Epub:
Not Epub Abstract:
Exon skipping therapy using synthetic DNA-like molecules called antisense oligonucleotides (ASOs) is a promising therapeutic... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Miyatake S, Mizobe Y, Takizawa H, Hara Y, Yokota T, Takeda S, Aoki Y. Exon Skipping Therapy Using Phosphorodiamidate Morpholino Oligomers in the mdx52 Mouse Model of Duchenne Muscular Dystrophy. Methods Mol Biol. 2018;1687:123-141. doi: 10.1007/978-1-4939-7374-3_9. |
GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency
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Citation:
PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1708341114 Epub:
Yes Abstract:
To elucidate the molecular basis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with... Delivery Method:
microinjection Organism or Cell Type:
Rhesus macaque (monkey) Citation Extract: Krendl C, Shaposhnikov D, Rishko V, Ori C, Ziegenhain C, Sass S, Simon L, Müller NS, Straub T, Brooks KE, Chavez SL, Enard W, Theis FJ, Drukker M. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. PNAS USA. 2017;[Epub ahead of print] doi:10.1073/pnas.1708341114. |
The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle
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Citation:
Sci Rep. 2017;7:14077 doi:10.1038/s41598-017-13688-3 Epub:
Not Epub Abstract:
Control of protein turnover is critical for meiotic progression. Using RiboTag immunoprecipitation, RNA binding protein... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Han SJ, Martins JPS, Yang Y, Kang MK, Daldello EMD, Conti M. The Translation of Cyclin B1 and B2 is Differentially Regulated during Mouse Oocyte Reentry into the Meiotic Cell Cycle. Sci Rep. 2017;7:14077 doi:10.1038/s41598-017-13688-3. |
In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology
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Citation:
Cell Rep. 2017;21:953-965. doi:10.1016/j.celrep.2017.10.010 Epub:
Not Epub Abstract:
Genetic alterations impacting ubiquitously expressed proteins involved in RNA metabolism often result in neurodegenerative... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Bernabo P, Tebaldi T, Groen EJN, Lane FM, Perenthaler E, Mattedi F, Newbery HJ, Zhou H, Zuccotti P, Potrich V, Shorrock HK, Muntoni F, Quattrone A, Gillingwater TH, Viero G. In Vivo Translatome Profiling in Spinal Muscular Atrophy Reveals a Role for SMN Protein in Ribosome Biology. Cell Rep. 2017;21:953-965. doi:10.1016/j.celrep.2017.10.010. |