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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Identification of Staphylococcus aureus Factors Required for Pathogenicity and Growth in Human Blood

Authors:
Connolly J, Boldock E, Prince LR, Renshaw SA, Whyte MK, Foster SJ
Citation:
Infect Immun. 2017 Oct 18;85(11). pii: e00337-17. doi: 10.1128/IAI.00337-17
Epub:
Not Epub
Abstract:
Staphylococcus aureus is a human commensal but also has devastating potential as an opportunistic pathogen. S. aureus...
Link:
http://iai.asm.org/content/85/11/e00337-17.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Connolly J, Boldock E, Prince LR, Renshaw SA, Whyte MK, Foster SJ. Identification of Staphylococcus aureus Factors Required for Pathogenicity and Growth in Human Blood. Infect Immun. 2017 Oct 18;85(11). pii: e00337-17. doi: 10.1128/IAI.00337-17.

Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury

Authors:
Wan Y, McDaniel K, Wu N, Ramos-Lorenzo S, Glaser T, Venter J, Francis H, Kennedy L, Sato K, Zhou T, Kyritsi K, Huang Q, Annable T, Wu C, Glaser S, Alpini G, Meng F
Citation:
Am J. Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.08.027
Epub:
Yes
Abstract:
Alcoholic liver disease remains a major cause of liver-related morbidity and mortality, which ranges from alcoholic...
Link:
http://ajp.amjpathol.org/article/S0002-9440(17)30583-7/fulltext
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Wan Y, McDaniel K, Wu N, Ramos-Lorenzo S, Glaser T, Venter J, Francis H, Kennedy L, Sato K, Zhou T, Kyritsi K, Huang Q, Annable T, Wu C, Glaser S, Alpini G, Meng F. Regulation of Cellular Senescence by miR-34a in Alcoholic Liver Injury. Am J. Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.08.027.

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

Authors:
Lagendijk AK, Gomez GA, Baek S, DHesselson D, Hughes WE, Paterson S, Conway DE, Belting H-G, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM
Citation:
Nat Comm. 2017;8:1402. doi:10.1038/s41467-017-01325-6
Epub:
Not Epub
Abstract:
Forces play diverse roles in vascular development, homeostasis and disease. VE-cadherin at endothelial cell-cell junctions...
Link:
https://www.nature.com/articles/s41467-017-01325-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lagendijk AK, Gomez GA, Baek S, DHesselson D, Hughes WE, Paterson S, Conway DE, Belting H-G, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM. Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish. Nat Comm. 2017;8:1402. doi:10.1038/s41467-017-01325-6.

Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies

Authors:
Ryan R, Failler M, Reilly ML, Garfa-Traore M, Delous M, Filhol E, Reboul T, Bole-Feysot C, Nitschké P, Baudouin V, Amselem S, Escudier E, Legendre M, Benmerah A, Saunier S
Citation:
Hum Mol Genet. 2017 Nov 7. doi: 10.1093/hmg/ddx396. [Epub ahead of print]
Epub:
Yes
Abstract:
A child presenting with Mainzer-Saldino syndrome (MZSDS), characterized by renal, retinal and skeletal involvements, was also...
Link:
https://academic.oup.com/hmg/article/doi/10.1093/hmg/ddx396/4600050
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ryan R, Failler M, Reilly ML, Garfa-Traore M, Delous M, Filhol E, Reboul T, Bole-Feysot C, Nitschké P, Baudouin V, Amselem S, Escudier E, Legendre M, Benmerah A, Saunier S. Functional characterization of tektin-1 in motile cilia and evidence for TEKT1 as a new candidate gene for motile ciliopathies. Hum Mol Genet. 2017 Nov 7. doi: 10.1093/hmg/ddx396. [Epub ahead of print].

Restoration of polr1c in early embryogenesis rescues the Type 3 Treacher Collins Syndrome facial malformation phenotype in zebrafish

Authors:
Kwong EML, Ho JCH, Lau MCC, You M-S, Jiang Y-J, Tse WKF
Citation:
Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.10.004
Epub:
Yes
Abstract:
Treacher Collins Syndrome (TCS) is a rare congenital birth disorder (1 in 50,000 live births) characterized by severe...
Link:
http://ajp.amjpathol.org/article/S0002-9440(17)30599-0/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kwong EML, Ho JCH, Lau MCC, You M-S, Jiang Y-J, Tse WKF. Restoration of polr1c in early embryogenesis rescues the Type 3 Treacher Collins Syndrome facial malformation phenotype in zebrafish. Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.10.004.

bmp3 is required for integrity of blood brain barrier by promoting pericyte coverage in zebrafish embryos

Authors:
Lei D, Jin X, Wen L, Dai H, Ye Z, Wang G
Citation:
Curr Mol Med. 2017 Nov 5. doi: 10.2174/1566524017666171106114234. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: The compromise of blood brain barrier (BBB) integrity is often associated with human hemorrhage stroke and...
Link:
http://www.eurekaselect.com/156823
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lei D, Jin X, Wen L, Dai H, Ye Z, Wang G. bmp3 is required for integrity of blood brain barrier by promoting pericyte coverage in zebrafish embryos. Curr Mol Med. 2017 Nov 5. doi: 10.2174/1566524017666171106114234. [Epub ahead of print].

Roles for Xenopus aquaporin-3b (aqp3.L) during gastrulation: fibrillar fibronectin and tissue boundary establishment in the dorsal margin

Authors:
Forecki J, Van Antwerp DJ, Lujan SM, Merzdorf CS
Citation:
Dev Biol. 2017 Nov 4. pii: S0012-1606(17)30026-X. doi: 10.1016/j.ydbio.2017.11.001. [Epub ahead of print]
Epub:
Yes
Abstract:
Aquaporins and aquaglyceroporins are a large family of membrane channel proteins that allow rapid movement of water and small,...
Link:
http://www.sciencedirect.com/science/article/pii/S001216061730026X
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Forecki J, Van Antwerp DJ, Lujan SM, Merzdorf CS. Roles for Xenopus aquaporin-3b (aqp3.L) during gastrulation: fibrillar fibronectin and tissue boundary establishment in the dorsal margin. Dev Biol. 2017 Nov 4. pii: S0012-1606(17)30026-X. doi: 10.1016/j.ydbio.2017.11.001. [Epub ahead of print].

SDS-PAGE Procedure: Application for Characterization of New Entirely Uncharged Nucleic Acids Analogues

Authors:
Pavlova AS, Dyudeeva ES, Kupryushkin MS, Amirkhanov NV, Pyshnyi DV, Pyshnaya IA
Citation:
Electrophoresis. 2017 Nov 7. doi: 10.1002/elps.201700415. [Epub ahead of print]
Epub:
Yes
Abstract:
SDS-PAGE is considered to be a universal method for size-based separation and analysis of proteins. In this study, we applied...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/elps.201700415/abstract
Citation Extract:
Pavlova AS, Dyudeeva ES, Kupryushkin MS, Amirkhanov NV, Pyshnyi DV, Pyshnaya IA. SDS-PAGE Procedure: Application for Characterization of New Entirely Uncharged Nucleic Acids Analogues. Electrophoresis. 2017 Nov 7. doi: 10.1002/elps.201700415. [Epub ahead of print].

Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish

Authors:
Cheng X-N, Shao M, Li J-T, Wang Y-F, Qi J, Xu Z-G, Shi D-L
Citation:
Nat Comm. 2017;8:1353. doi:10.1038/s41467-017-01552-x
Epub:
Not Epub
Abstract:
Gastrulation is a fundamental morphogenetic event that requires polarised cell behaviours for coordinated asymmetric cell...
Link:
https://www.nature.com/articles/s41467-017-01552-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng X-N, Shao M, Li J-T, Wang Y-F, Qi J, Xu Z-G, Shi D-L. Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish. Nat Comm. 2017;8:1353. doi:10.1038/s41467-017-01552-x.

MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli

Authors:
Daly SM, Sturge CR, Felder-Scott CF, Geller BL, Greenberg DE
Citation:
mBio. 2017;8:e01315-17. doi:10.1128/mBio.01315-17
Epub:
Not Epub
Abstract:
In late 2015, the first example of a transferrable polymyxin resistance mechanism in Gram-negative pathogens, MCR-1, was...
Link:
http://mbio.asm.org/content/8/6/e01315-17.short
Delivery Method:
peptide-linked
Organism or Cell Type:
mice, Escherichia coli
Citation Extract:
Daly SM, Sturge CR, Felder-Scott CF, Geller BL, Greenberg DE. MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli. mBio. 2017;8:e01315-17. doi:10.1128/mBio.01315-17.

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